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Altered bone marrow niche forms central innate immune memory driving cardiac dysfunction
We previously showed that heart failure induces innate immune memory in hematopoietic stem and progenitor cells, which contributes to recurrence of heart failure and impaired stress responses in multiple organs. While the bone marrow microenvironment …
Publication
Fibroblast Growth Factor 7 Limits Fibroblast-Driven Matrix Remodeling in Abdominal Aortic Aneurysm
Abdominal aortic aneurysm (AAA) is a chronic vascular disorder characterized by progressive aortic dilation and extracellular matrix remodeling, for which effective pharmacological therapies remain limited. Fibroblast growth factor 7 (FGF7), a paracrine …
Publication
Shear Wave Elasticity Imaging for Monitoring Risk of Skin Breakdown Following Subcutaneous Implantation
Subcutaneous implants are widely used in craniofacial reconstruction to restore structural integrity and aesthetics; however, complications such as skin breakdown and implant exposure remain common and can significantly impact patient outcomes. These …