Ischemia / Reperfusion
Investigate tissue ischemia in vivo and in real time
Study Tissue Ischemia and Blood Reperfusion in Real Time!
Obtain dynamic measurements of oxygen saturation and vascular reperfusion in your disease model.
Tissue ischemia, as well as blood reperfusion in ischemic organs, can be investigated in vivo and in real-time with the Vevo LAZR-X system. The physiological and biochemical changes induced in the affected tissue or organ hold important clinical relevance in studies of disease and development of therapeutics.
Features include:
- Anatomy-specific oxygen saturation and total hemoglobin measurement
- Detection and quantification of biomarkers (eg. VEGFR2, VCAM)
- Assessing angiogenesis progression
- Quantifying perfusion kinetics
- Blood flow measurements
Acute ischemia induced in mouse hindlimb with a tourniquet showing oxygen saturation during ischemia and post-reperfusion



Use a Vevo System for:
- Femoral Artery Ligation models
- Peripheral Artery Disease assessment
- Ischemic Bowel Disease (Ischaemic Colitis)
- Myocardial infarct
- Stroke studies
- Wound healing and tissue injury
Downloaded or access resources related to Study Tissue Ischemia and Blood Reperfusion in Real Time!
Displaying 1 - 5 of 48 results found
Brain-targeted hypoxia-inducible factor stabilization reduces neonatal hypoxic-ischemic brain injury
Chia-Yi Kuan, Hong-Ru Chen, Ning Gao, Yi-Min Kuo, Ching-Wen Chen, Dianer Yang, Melissa M. Kinkaid, Erding Hu, Yu-Yo Sun
Neurobiology of Disease
.2021
;Experimental Myocardial Infarction Elicits Time-Dependent Patterns of Vascular Hypoxia in Peripheral Organs and in the Brain
Hélène David, Aurore Ughetto, Philippe Gaudard, Maëlle Plawecki, Nitchawat Paiyabhroma, Emma Zub, Pascal Colson, Sylvain Richard, Nicola Marchi, Pierre Sicard
Frontiers in Cardiovascular Medicine
.2021
;Hypoxia-induced miR-210 modulates the inflammatory response and fibrosis upon acute ischemia
Zaccagnini Germana, Greco Simona, Longo Marialucia, Maimone Biagina, Voellenkle Christine, Fuschi Paola, Carrara Matteo, Creo Pasquale, Maselli Davide, Tirone Mario, Mazzone Massimiliano, Gaetano Carlo, Spinetti Gaia, Martelli Fabio
Cell Death and Disease
.2021
;Dental Pulp Mesenchymal Stem Cells Attenuate Limb Ischemia via Promoting Capillary Proliferation and Collateral Development in a Preclinical Model
Youfeng Li, Yuning Zhang, Hua Wang, Chengfeng Sun, Dongmei Liu, Hongying Liu, Jia He, Furong Chen, Weiting Wang, Xi Jiang, Chu Tse Wu, Yuefeng Yang
Stem Cells International
.2021
;Evaluation of Hemodynamics in a Murine Hindlimb Ischemia Model Using Spatial Frequency Domain Imaging
Katherine A. Leyba, Sandhya Vasudevan, Thomas D. O'Sullivan, Craig J. Goergen
Lasers in Surgery and Medicine
.2020
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Can I measure tumor hypoxia with the Vevo system?
Yes, oxygen saturation can be easily measured using our Vevo LAZR-X photoacoustics system...
When performing a PA region analysis on a Oxy-Hemo Mode datasets, what is the difference between sO2 Avr and sO2 Avr Total? What is the difference between HbT Avr and HbT?
sO2 Avr measurements represent the...