Study Tissue Ischemia and Blood Reperfusion in Real Time
Obtain real-time dynamic measurements of oxygen saturation and vascular reperfusion in your disease model.
Tissue ischemia, as well as blood reperfusion in ischemic organs, can be investigated in vivo and in real-time with the Vevo F2 LAZR-X20 photoacoustic system.
The physiological and biochemical changes induced in the affected tissue or organ hold important clinical relevance in studies of disease and development of therapeutics.
Features include:
- Anatomy-specific oxygen saturation and total hemoglobin measurement
- Detection and quantification of biomarkers (eg. VEGFR2, VCAM)
- Assessing angiogenesis progression
- Quantifying perfusion kinetics
- Blood flow measurements
Use a Vevo System for:
- Femoral Artery Ligation models
- Peripheral Artery Disease assessment
- Ischemic Bowel Disease (Ischaemic Colitis)
- Myocardial infarct
- Stroke studies
- Wound healing and tissue injury
Example Study
B-Mode
Acute ischemia induced in mouse hindlimb with a tourniquet.
During Ischemia
Acute ischemia induced in mouse hindlimb with a tourniquet showing oxygen saturation during ischemia.
Post-reperfusion
Acute ischemia induced in mouse hindlimb with a tourniquet showing oxygen saturation post-reperfusion.
Gallery
Publications
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