Study Tissue Ischemia and Blood Reperfusion in Real Time!

Obtain dynamic measurements of oxygen saturation and vascular reperfusion in your disease model.

Tissue ischemia, as well as blood reperfusion in ischemic organs, can be investigated in vivo and in real-time with the Vevo LAZR-X system. The physiological and biochemical changes induced in the affected tissue or organ hold important clinical relevance in studies of disease and development of therapeutics.

Features include:

• Anatomy-specific oxygen saturation and total hemoglobin measurement
• Detection and quantification of biomarkers (eg. VEGFR2, VCAM)
• Assessing angiogenesis progression
• Quantifying perfusion kinetics
• Blood flow measurements

Acute ischemia induced in mouse hindlimb with a tourniquet showing oxygen saturation during ischemia and post-reperfusion

Mouse hindlimb with tourniquet

Acute ischemia

Post-reperfusion

Use a Vevo System for:

• Femoral Artery Ligation models
• Peripheral Artery Disease assessment
• Ischemic Bowel Disease (Ischaemic Colitis)
• Myocardial infarct 
• Stroke studies
• Wound healing and tissue injury