Tissue Ischemia / Reperfusion
Investigate tissue ischemia in vivo and in real time
Study Tissue Ischemia and Blood Reperfusion in Real Time!
Obtain dynamic measurements of oxygen saturation and vascular reperfusion in your disease model.
Tissue ischemia, as well as blood reperfusion in ischemic organs, can be investigated in vivo and in real-time with the Vevo LAZR-X system. The physiological and biochemical changes induced in the affected tissue or organ hold important clinical relevance in studies of disease and development of therapeutics.
Features include:
- Anatomy-specific oxygen saturation and total hemoglobin measurement
- Detection and quantification of biomarkers (eg. VEGFR2, VCAM)
- Assessing angiogenesis progression
- Quantifying perfusion kinetics
- Blood flow measurements
Acute ischemia induced in mouse hindlimb with a tourniquet showing oxygen saturation during ischemia and post-reperfusion
Use a Vevo System for:
- Femoral Artery Ligation models
- Peripheral Artery Disease assessment
- Ischemic Bowel Disease (Ischaemic Colitis)
- Myocardial infarct
- Stroke studies
- Wound healing and tissue injury
Displaying 1 - 5 of 42 results found
Impact of Age on Disease Progression and Microenvironment in Oral Cancer
V.K. Vincent-Chong, H. DeJong, L.J. Rich, A. Patti, M. Merzianu, P.A. Hershberger, M Seshadri
Journal of Dental Research
.2018
;Remote Ischemic Postconditioning Protects against Myocardial Ischemia-Reperfusion Injury by Inhibition of the RAGE-HMGB1 Pathway
Xiangming Wang, Junhong Wang, Tiantian Tu, Zakaria Iyan, Deeraj Mungun, Zhijian Yang, Yan Guo
2018
;PAFR-deficiency alleviates myocardial ischemia/reperfusion injury in mice via suppressing inflammation, oxidative stress and apoptosis
En wei Wang, Yang yang Han, Xu sheng Jia
Biochemical and Biophysical Research Communications
.2018
;Honokiol Ameliorates Myocardial Ischemia/Reperfusion Injury in Type 1 Diabetic Rats by Reducing Oxidative Stress and Apoptosis through Activating the SIRT1-Nrf2 Signaling Pathway
Bin Zhang, Mengen Zhai, Buying Li, Zhenhua Liu, Kaifeng Li, Liqing Jiang, Meng Zhang, Wei Yi, Jian Yang, Dinghua Yi, Hongliang Liang, Zhenxiao Jin, Weixun Duan, Shiqiang Yu
Oxidative Medicine and Cellular Longevity
.2018
;EphrinA1-Fc attenuates myocardial ischemia/reperfusion injury in mice
Augustin DuSablon, Justin Parks, K’Shylah Whitehurst, Heather Estes, Robert Chase, Eleftherios Vlahos, Uma Sharma, David Wert, Jitka Virag
PLOS ONE
.2017
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