Cardiology
Rapid, Repeatable Echocardiography for Small to Larger Animals
Ultra-high frequency (UHF) ultrasound provides superior resolution and will have an incredible impact on cardiovascular research in your animal models.
Perform reliable echocardiography in mice and other small animals for translational cardiovascular research with in vivo resolution down to 30 microns.
Vevo ultrasound imaging platforms provide the best temporal and spatial resolution compared to MRI, conventional ultrasound and CT.
With the Vevo imaging systems you can:
- Perform cardiovascular phenotyping for cardiac structure and function, ideal for stress echo and cardiotoxicity studies
- Image the heart in 4D!
- Quantify diastolic dysfunction
- Evaluate cardiac strain (global or regional synchrony and deformation)
- Perform image-guided cardiac injections
- Monitor full animal physiology while imaging, including body temperature, ECG and respiratory rate
- Assess myocardial oxygen saturation
Cardiac 4D Imaging
Quantify ejection fraction and fractional shortening with more accuracy than traditional echocardiography, and faster than cardiac MRI!
Cardiovascular Workshop
The Heart of the Matter
If you missed this advanced workshop on COVID-19 and other preclinical cardiac disease models, here's your chance to catch up.
Gallery
Color Doppler of Mouse Aortic Arch
Color Doppler image of an aortic arch in a female mouse, acquired using a UHF57x transducer on the Vevo F2.
Murine Carotid Artery
Murine Apical Color Doppler
Murine apical color Doppler scanned using a UHF46x transducer.
Publications
TOP PAPER
Quantification of murine myocardial infarct size using 2-D and 4-D high-frequency ultrasound
American Journal of Physiology-Heart and Circulatory Physiology
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TOP PAPER
Improving characterization of hypertrophy-induced murine cardiac dysfunction using four-dimensional ultrasound derived strain mapping
American Journal of Physiology-Heart and Circulatory Physiology
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TOP PAPER
Machine learning driven contouring of high-frequency four-dimensional cardiac ultrasound data
Applied Sciences (Switzerland)
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TOP PAPER
Echocardiographic speckle-tracking based strain imaging for rapid cardiovascular phenotyping in mice
Circulation Research
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TOP PAPER
Induced pluripotent stem cell intervention rescues ventricular wall motion disparity, achieving biological cardiac resynchronization post-infarction
Journal of Physiology
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TOP PAPER
Uncoupling DNA damage from chromatin damage to detoxify doxorubicin
Proceedings of the National Academy of Sciences
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TOP PAPER
Novel insights into the genetic landscape of congenital heart disease with systems genetics
Progress in Pediatric Cardiology
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TOP PAPER
Toward standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function
Cardiovascular Research
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