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Publication
The hidden impact of cage position on behavioral phenotyping and reproducibility
The hidden impact of cage position on behavioral phenotyping and reproducibility …
Publication
Nanocatalytic Immunotherapy Targeting Tumor-Resident Intracellular Bacteria for Triple-Negative Breast Cancer Treatment and Metastasis Suppression
Tumor-resident intracellular bacteria (TRIB) are prevalent within triple-negative breast cancer (TNBC). As integral components of the tumor pathological microenvironment, TRIB accelerate TNBC development by regulating cell proliferation, metabolism and …
Publication
High-Resolution Imaging via UHF-US–Based 3D Reconstruction in a 3D In Vivo Tumor Model
The chorioallantoic membrane (CAM) model resembles a preclinical in vivo platform for the engraftment of different tumors and is especially well-suited for the development and evaluation of novel cancer therapies. Due to the CAM′s extensive vascular …
Publication
Baricitinib Attenuates Dermal and Pulmonary Fibrosis in a Bleomycin-Induced Murine Scleroderma Model: A Longitudinal High-Frequency Ultrasonography Study
Background: The bleomycin (BLM)-induced murine model is the most widely used experimental model of systemic sclerosis, yet fibrosis is conventionally verified only at sacrifice. We asked whether high-frequency ultrasonography (HFUS) can track dermal …
Publication
Dual enzyme-powered nanomotors for cascade-amplified sonodynamic therapy of prostate cancer
The clinical application of sonodynamic therapy (SDT) remains limited by the intrinsic hypoxic tumor microenvironment and sonosensitizer accumulation, while starvation therapy suffers from enzymatic activity in vivo . To address these challenges, we …
Publication
EFFECT OF SEVOFLURANE ON MIGRATION AND INVASION OF CERVICAL CANCER CELLS IN RATS BY REGULATING HIPPO-YAP/TAZ SIGNALING
This research set out to explore how sevoflurane anesthesia modulates the migratory and invasive capacities of cervical cancer cells in rats through the regulation of the Hippo-YAP/TAZ signaling pathway, providing experimental evidence for optimizing …
Publication
Porphyrin-based iron-MOF nanoprobe for photoacoustic sensing in a Cu 2+ -Aβ-associated oxidative microenvironment model
The Cu[Formula: see text]-A[Formula: see text] interaction is closely linked to the metal-ion imbalance, peptide aggregation and oxidative stress of Alzheimer’s disease-related microenvironments. Here we report a porphyrin-based iron metal-organic …
Publication
In Vivo Intravesical Photoacoustic Imaging via Catheter-Based Light Delivery: A Porcine Feasibility Study with Gold Nanoconstructs
In Vivo Intravesical Photoacoustic Imaging via Catheter-Based Light Delivery: A Porcine Feasibility Study with Gold Nanoconstructs …
Event
Advancing Preclinical Neuroimaging with Super-Resolution Ultrasound and Ultrafast Doppler
Explore how advanced ultrasound methods are expanding preclinical vascular and brain research. Matthew Lowerison, Ph.D., Research Scientist in Biomedical Engineering at Duke University, will introduce super-resolution ultrasound localization microscopy …
Event
32nd European symposium on Ultrasound Contrast Imaging
ESUCI is designed to share the latest developments on contrast agents in radiology and cardiology, new imaging modalities, drug delivery, tissue targeted imaging, competing technologies and new potential clinical applications. FUJIFILM VisualSonics …