Vascular Biology
Preclinical Ultrasound for Vascular Biology Research
Visualize and Quantify Vascular Function
Ultra-high Frequency (UHF) Vevo imaging systems allow for non-invasive, real-time evaluation of vascular function with resolution down to 30 microns.
With UHF imaging and software, you can:
- Quantify pulse wave velocity and vascular resistance
- Detect aneurysm and plaque formation with 3D reconstruction
- Analyze vessel wall characteristics (i.e. diameter, strain, velocity, stiffness, etc.)
- Quantify blood flow and perfusion
Perfect for Animal Models of:
- Atherosclerosis
- Aneurysm
- Arteriosclerosis
- Vascular Ischemia
Vascular Biology
Right Femoral Artery Bifurcation in a Mouse
Gallery
Abdominal Aorta Used In Strain Analysis
B-mode image of the abdominal aorta with vessel wall velocity vector arrows used in strain analysis.
M-Mode of a Mouse Carotid Artery
M-mode image of mouse left common carotid.
Measurements: wall thickness and vessel diameter in systole and diastole.
Splenic Vasculature in a Mouse
Murine Renal Vasculature in 3D
3D Spleen and Kidney Vasculature
3D Power Doppler rendering of a mouse spleen and kidney, highlighting splenic and renal vasculature.
Blood flow in tumor
3D rendered high-resolution ultrasound (greyscale) and color Doppler (orange and blue) image of a subcutaneous tumor showing blood flow.
Blood flow in tumor
Blood flow in tumor
3D rendered high-resolution ultrasound (greyscale) and color Doppler (orange and blue) image of a subcutaneous tumor showing blood flow.
Publications
Thermoresponsive polymer encapsulated HT1080 exosomes lyse localized blood clot: A preclinical evaluation in rat carotid artery thrombosis model
Journal of Drug Delivery Science and Technology
, Glutamine Protects against Mouse Abdominal Aortic Aneurysm through Modulating VSMC Apoptosis and M1 Macrophage Activation
International Journal of Medical Sciences
, Pentamethylquercetin attenuates angiotensin II-induced abdominal aortic aneurysm formation by blocking nuclear translocation of C/EBPβ at Lys253
Biochimica et Biophysica Acta - Molecular Basis of Disease
, Exploring the role of myeloperoxidase in the atherosclerotic process in hypoxic mice based on the MAPK signaling pathway
Biochemical Pharmacology
, Neutrophil extracellular traps formation may be involved in the association of propranolol with the development of portal vein thrombosis
Thrombosis Research
, Transformation of metallo-elastomer grafts in a carotid artery interposition model over a year
Biomaterials
, Urotensin II receptor deficiency ameliorates ligation-induced carotid intimal hyperplasia partially through the RhoA-YAP1 pathway
Biochimica et Biophysica Acta - Molecular Basis of Disease
, Reduced fetal cerebral blood flow predicts perinatal mortality in a mouse model of prenatal alcohol and cannabinoid exposure
BMC Pregnancy and Childbirth
, Mitochondrial targeted catalase improves muscle strength following arteriovenous fistula creation in mice with chronic kidney disease
Scientific Reports
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