Oncology
Characterize Tumors In Vivo and Non-invasively with Ultra-High Frequency (UHF) Ultrasound
Your powerful, high resolution multi-modal imaging solution for translational cancer research.
Conduct high-throughput screenings for tumor growth and detect and monitor growth and response of tumors to therapy at multiple time points in preclinical disease models all in vivo. In addtion, you can image the tumor microenvironment for changes and you have a powerful multi-modal platform for oncology research.
With the Vevo Imaging Systems you can:
- Non-invasively characterize tumor tissue in vivo
- Screen for very small lesions (resolution down to 30µm); early detection
- Accurately quantify volume of orthotopic and subcutaneous tumors longitudinally
- Perform rapid tumor volume assessments with a dedicated Oncology Measurement Package
- Visualize and quantify angiogenesis, vasculature and perfusion
- Measure hypoxia
- Assess biomarker or drug distribution
- Develop models using ultrasound-guided injections
Explore a Wide Range of Applications
A Comprehensive Solution for Pancreatic Cancer Researchers
VisualSonics offers you a complete imaging solution for orthotopic pancreatic cancer models, from model generation with image-guided injection to characterization of the tumor micro-environment.
Advance Cancer Research Using Molecular Imaging
Explore high-frequency ultrasound and photoacoustics for in vivo molecular imaging of targeted agents, theranostics and nanomedicine.
Vevo 4 Oncology Web Series
Pancreatic and Liver Tumor Imaging
Watch the first episode of the Vevo 4 Oncology Web Series, presented by Prof. Annarosa Arcangeli, and learn more about a powerful, high resolution multi-modal imaging solution for oncology. Now available on-demand!
Gallery
Breast tumor in 3D
Tumor 3D
3D Volume Reconstruction of a Murine Tumor
Nanoparticle distribution in tumor
3D rendered high-resolution ultrasound (greyscale) and spectrally unmixed photoacoustic (red, blue and gold) image of a subcutaneous tumor showing nanoparticle distribution (yellow) as well as oxygenated (red) and deoxygenated (blue) hemoglobin signal.
Mouse whole body with tumor
Whole body image of a mouse with a subcutaneous tumor visible on the flank, imaged with high frequency ultrasound on the Vevo F2 system.
ICG localization in tumor
Oxygen saturation in tumor
Publications
TOP PAPER
Intraluminal gel ultrasound and eco-color doppler: new tools for the study of colorectal cancer in mice.
In vivo (Athens, Greece)
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TOP PAPER
Assessment and Monitoring Tumor Vascularity With Contrast-Enhanced Ultrasound Maximum Intensity Persistence Imaging
Investigative Radiology
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TOP PAPER
Anti-VEGF therapy reduces intestinal inflammation in Endoglin heterozygous mice subjected to experimental colitis
Angiogenesis
, A simple and robust nanosystem for photoacoustic imaging of bladder cancer based on α5β1-targeted gold nanorods
Journal of Nanobiotechnology
, Glucose-responsive enzymatic biomimetic nanodots for H2O2 self-supplied catalytic photothermal/chemodynamic anticancer therapy
Acta Biomaterialia
, Cancer characterization using light backscattering spectroscopy and quantitative ultrasound: an ex vivo study on sarcoma subtypes
Scientific Reports
, Desmoplastic stroma restricts T cell extravasation and mediates immune exclusion and immunosuppression in solid tumors
Nature Communications
, Contrast-enhanced ultrasound imaging for monitoring the efficacy of near-infrared photoimmunotherapy
eBioMedicine
, Tracking adoptive natural killer cells via ultrasound imaging assisted with nanobubbles
Acta Biomaterialia
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