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Publication
Translational therapeutics in genetically engineered mouse models of cancer.
Advances in knowledge of the molecular alterations of human cancers, refinements in technologies for the generation of genetically engineered mouse models (GEMMs), and the development of cancer therapies have accelerated in recent years. Progress in these …
Publication
A Polymeric Nanoparticle Encapsulated Small-Molecule Inhibitor of Hedgehog Signaling (NanoHHI) Bypasses Secondary Mutational Resistance to Smoothened Antagonists
Aberrant activation of the hedgehog (Hh) signaling pathway is one of the most prevalent abnormalities in human cancer. Tumors with cell autonomous Hh activation (e.g., medulloblastomas) can acquire secondary mutations at the Smoothened (Smo) antagonist …
Publication
CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer.
Pancreatic ductal adenocarcinoma (PDA) is characterized by abundant desmoplasia and poor tissue perfusion. These features are proposed to limit the access of therapies to neoplastic cells and blunt treatment efficacy. Indeed, several agents that target …
Product application
Cardiovascular Biology
Perform rapid, repeatable echocardiography in small to large animals in vivo with resolution down to 30 μm. Vevo ultrasound imaging platforms provide the best temporal and spatial resolution compared to MRI, conventional ultrasound and CT. The Vevo F2xc …
Product
Vevo 3100
This product has now entered the retirement phase. Our latest platform, the Vevo F2xc Imaging System, employs technological advances in a broad range of areas that help transcend many barriers. The Vevo F2xc provides both ultra-high and low frequency …
Product
Vevo 2100
IMPORTANT! Dear Valued Customer, At FUJIFILM VisualSonics Inc. (FF-VSI), we are committed to providing the highest quality products and services to our customers. The Vevo 2100 Imaging System is now discontinued. All technology products eventually reach …
Product
Vevo 770
Uptrade to a Vevo F2 The Vevo 770 High-Resolution In Vivo Micro-Imaging System is no longer offered for sale as of December 31, 2013. Please contact us to find out about Vevo 770 customer loyalty discount opportunities towards a new system. With an …
Product
Vevo CQ Software
Vevo CQ is a post-processing tool which can be used on numerous tissues, organs and tumor models, including subcutaneous tumors, abdominal organs and hind limb muscles. The Vevo CQ software allows users to study contrast uptake kinetics as well as late …
Product
Vevo Vasc Software
Vevo Vasc Analysis Software is a vascular strain analysis package that utilizes advanced speckle tracking algorithms on high-resolution ultrasound data to quantify vascular pathologies non-invasively and in vivo. It is the first software of its kind …
Product
Nanoparticles
Seeing molecules with nanoparticle contrast using photoacoustics Nano-scale materials are increasingly used as molecular imaging agents for photoacoustics due to their very high absorption of light in the NIR range and their customizeability in terms of …