Background/objectives: This study was designed to investigate the involvement of sympathetic innervation within perivascular adipose tissue (PVAT) during exercise regulating arterial stiffness in obese rats, and the potential neuro-vascular mechanism. …

Photoacoustic (PA) imaging combines the molecular specificity of optical absorption with the resolution and depth of ultrasound, enabling noninvasive molecular imaging in vivo. However, robust and accurate PA multiplexing is hindered by the broad spectra …

Rapid advances in synthetic biology are driving the development of microbes as therapeutic agents. While the immunosuppressive tumor microenvironment creates a favorable niche for the systematic delivery of bacteria and therapeutic payloads, these can be …

Rejuvenation of corticospinal neurons enhances rehabilitation-associated corticospinal tract axon sprouting and functional recovery post photothrombotic ischemic stroke in …

Random-pattern skin flaps are widely employed in tissue reconstruction, however, their survival is frequently hindered by ischemia, leading to necrosis. Metabolic alterations have been implicated in playing critical roles in angiogenesis during tissue …

Vascular smooth muscle cells (VSMCs) plays an important role in maintaining vascular function by responding to various vasoactive stimuli within blood vessels. Far-infrared (FIR) rays has been shown to possess a variety of physiological effects including …

Pulmonary fibrosis (PF) is a major cause of morbidity and mortality. Although increased oxidative stress and altered metabolism are implicated in PF pathobiology, our knowledge regarding the contribution of the glucose metabolism to the synthesis of …

This proof-of-concept study evaluated the performance of high-frequency ultrasound (HFUS, 40 MHz) for monitoring changes in alveolar bone loss and determining its detection capability and measurement precision. The study aimed to quantify system error, …

Vascular endothelial growth factor receptor-targeting tyrosine kinase inhibitors (VEGFR-TKIs) and anti-PD-1 (aPD-1) combinations are effective in multiple solid tumors, particularly in clear cell renal cell carcinoma (ccRCC), due to its characteristic …