Search
Publication
Very High Resolution Ultrasound Imaging for Real-Time Quantitative Visualization of Vascular Disruption after Spinal Cord Injury
Spinal cord injury (SCI) is characterized by vascular disruption with intramedullary hemorrhage, alterations in blood- spinal cord barrier integrity, and perilesional ischemia. A safe and easily applied imaging technique to quantify evolving intraspinal …
Publication
Preclinical efficacy of bevacizumab with CRLX101, an investigational nanoparticle-drug conjugate, in treatment of metastatic triple-negative breast cancer
VEGF-pathway targeting antiangiogenic drugs, such as bevacizumab, when combined with chemotherapy have changed clinical practice for the treatment of a broad spectrum of human cancers. However, adaptive resistance often develops and one major mechanism is …
Publication
A Robust Design for Cellular Vehicles of Gold Nanorods for Multimodal Imaging
The pursuit of more selectivity in the delivery of plasmonic particles to tumors is critical before their penetration into clinical applications as the photoacoustic imaging and the photothermal ablation of cancer. As their direct infusion into the …
Publication
Strategies for non-invasive imaging of polymeric biomaterial in vascular tissue engineering and regenerative medicine using ultrasound and photoacoustic techniques
The ability of new polymericmaterials to provide excellent biomechanical properties expanded their potential for biomedical applications enormously. The use of non-invasive imaging modalities could provide crucial information to monitor the …
Publication
Photoacoustic imaging of angiogenesis in a subcutaneous islet transplant site in a murine model a subcutaneous islet transplant site in a murine model
Photoacoustic imaging of angiogenesis in a subcutaneous islet transplant site in a murine model a subcutaneous islet transplant site in a murine …
Publication
Gold Nanoparticle Coated Carbon Nanotube Ring with Enhanced Raman Scattering and Photothermal Conversion Property for Theranostic Applications
We report a new type of carbon nanotube ring (CNTR) coated with gold nanoparticles (CNTR@AuNPs) using CNTR as a template and surface attached redox-active polymer as a reducing agent. This nanostructure of CNTR bundle embedded in the gap of closely …
Publication
Gold nanoparticles for photoacoustic imaging.
Photoacoustic (PA) imaging is a biomedical imaging modality that provides functional information regarding the cellular and molecular signatures of tissue by using endogenous and exogenous contrast agents. There has been tremendous effort devoted to the …
Publication
In vitro photoacoustic visualization of myocardial ablation lesions
Background—Radiofrequency (RF) ablation to treat atrial arrhythmia is limited by an inability to reliably assess lesion durability and transmurality. Objective—Determine feasibility of photoacoustic characterization of myocardial ablation lesions in …
Publication
Biomedical photoacoustics beyond thermal expansion using triggered nanodroplet vaporization for contrast-enhanced imaging
Since being discovered by Alexander Bell, photoacoustics may again be seeing major resurgence in biomedical imaging. Photoacoustics is a non-ionizing, functional imaging modality capable of high contrast images of optical absorption at depths …
Publication
Dual In Vivo Photoacoustic and Fluorescence Imaging of Assessment , and Surgical Guidance
Biomarker-specific imaging probes offer ways to improve molecular diagnosis, intraoperative margin assessment, and tumor resection. Fluorescence and photoacoustic imaging probes are of particular interest for clinical applications because the combination …