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Multi-Wavelength Photoacoustic Visualization of High Intensity Focused Ultrasound Lesions
High intensity focused ultrasound (HIFU) thermal therapies are limited by deficiencies in existing image-guidance techniques. Previous studies using single-wavelength photoacoustic (PA) imaging have demonstrated that HIFU lesions generate contrast with …
Publication
Multi-stimuli responsive Cu 2 S nanocrystals as trimodal imaging and synergistic chemo-photothermal therapy agents
A size and shape tuned, multifunctional metal chalcogenide, Cu2S-based nanotheranostic agent is deve- loped for trimodal imaging and multimodal therapeutics against brain cancer cells. This theranostic agent was highly efficient in optical, photoacoustic …
Publication
Photoacoustic Imaging for Medical Diagnostics
Photoacoustic Imaging for Medical Diagnostics …
Publication
Graphene Meets Microbubbles: A Superior Contrast Agent for Photoacoustic Imaging
Coupling graphene with a soft polymer surface offers the possibility to build hybrid constructs with new electrical, optical, and mechanical properties. However, the low reactivity of graphene is a hurdle in the synthesis of such systems which is often …
Publication
In situ conversion of porphyrin microbubbles to nanoparticles for multimodality imaging
Converting nanoparticles or monomeric compounds into larger supramolecular structures by endogenous1,2 or external3,4 stimuli is increasingly popular because these materials are useful for imaging and treating diseases. However, conversion of …
Publication
Linear-array-based photoacoustic imaging of human microcirculation with a range of high frequency transducer probes
Photoacoustic imaging (PAI) with a linear-array-based probe can provide a convenient means of im- aging the human microcirculation within its native structural context and adds functional information. PAI using a multielement linear transducer array …
Publication
Semiconducting polymer nanoparticles as photoacoustic molecular imaging probes in living mice
Photoacoustic (PA) imaging holds great promise for the visualization of physiology and pathology at the molecular level with deep tissue penetration and fine spatial resolution. To fully utilize this potential, PA molecular imaging probes have to be …
Publication
Non-invasive Monitoring of Ultrasound-Stimulated Microbubble Radiation Enhancement Using Photoacoustic Imaging
Modulation of the tumour microvasculature has been demonstrated to affect the effectiveness of radiation, stimulating the search for anti-angiogenic and vascular-disrupting treatment modalities. Microbubbles stimulated by ultrasound have recently been …
Publication
Non-invasive multimodal functional imaging of the intestine with frozen micellar naphthalocyanines
There is a need for safer and improved methods for non-invasive imaging of the gastrointestinal tract. Modalities based on X-ray radiation, magnetic resonance and ultrasound suffer from limitations with respect to safety, accessibility or lack of adequate …
Publication
Folding Up of Gold Nanoparticle Strings into Plasmonic Vesicles for Enhanced Photoacoustic Imaging
The stepwise self-assembly of hollow plasmonic vesicles with vesicular membranes containing strings of gold nanoparticles (NPs) is reported. The formation of chain vesicles can be controlled by tuning the density of the polymer ligands on the surface of …