Background/Objectives: Neuroblastoma (NB) is the most common extracranial solid tumor in children and accounts for 12–15% of pediatric cancer-related deaths. Current multimodal therapies lack specific cellular targets, causing systemic toxicity and drug …

Real or simulated microgravity induces a senescence-like modification of carotid artery in both human and animal observations, with the mechanisms not fully elucidated. Here, we aim to elucidate the role of sterol regulatory element-binding protein 1 …

Solvent osmolarity and viscosity regulate lymph node pharmacokinetics and perinodal dynamics in lymphatic drug delivery …

Cardiovascular disease has become the leading cause of death. It is the common goal for researchers worldwide to develop small-diameter vascular grafts (SDVGs) which could meet clinical needs. In this study, PLGA@PCL core-shell structural fibrous SDVGs …

Treatment of clonal hematopoiesis associated atherosclerosis via vaccine-based clearance of the mutant cells …

Individuals born after intrauterine growth restriction (IUGR) are at increased risk of long-term cardiovascular complications, including elevated blood pressure, endothelial dysfunction, and arterial stiffness. Endothelial progenitor cells (EPCs), …

Magnetic resonance imaging (MRI) techniques are essential for the diagnosis of hepatocellular carcinoma (HCC) and the development of precise treatment strategies. Multifunctional diagnostic agents integrating MRI capabilities have attracted considerable …

Fetal intrauterine growth restriction (IUGR) is a common pregnancy complication that significantly impacts fetal health and long-term outcomes. Prenatal nicotine exposure (PNE) is a major environmental risk factor for IUGR, with abnormal placental …

Malignant serous effusion (MSE), including malignant pleural effusion (MPE) and malignant ascites (MA), is a common and severe complication in advanced malignancies, associated with poor prognosis and high recurrence rates. Currently, no standardized …

Autophagy plays either a suppressing or promoting role during tumor development. Clarifying the role of autophagy in bladder tumorigenesis both in vitro and in vivo is crucial for developing novel therapeutic strategies through manipulating autophagy …