GRB2 regulation of essential signaling pathways in the endometrium is critical for implantation and decidualization …

Atrial cardiomyocyte-restricted cleavage of gasdermin D promotes atrial arrhythmogenesis …

Objective: Abnormal hemodynamics is thought to play an essential role in the development of cardiovascular diseases. Mouse models are widely used for elucidating the underlying mechanisms; however, their small size and high heart rates make it difficult …

Intraoperative multispectral photoacoustic pathology assessment presents a promising approach to guide biopsy resection. In this study, we developed and validated a novel photoacoustic technique to differentiate between healthy and cancerous tissues. Our …

Gas therapy (GT) and/or phototherapy have been recently employed as immunogenic cell death (ICD) agents for activating immunotherapy, whereas the effective activation of sufficient immune responses remains an enormous challenge in such single therapeutic …

The limitations of current diagnostic imaging techniques and therapies for bladder cancer are associated with and responsible for the recurrence and progression of residual disease, with an impact on social costs and quality of life of patients. This …

Endothelial cell (EC) senescence is an accomplice for vascular aging, which leads to cardiovascular diseases (CVDs). Evidences showed that Hippo-Yes-associated protein (YAP) signaling pathway plays an essential role in aging-associated CVDs. Here, we …

Lnc-RAINY Regulates Genes Involved in Radiation Susceptibility Through DNA:DNA:RNA triplex-forming Interactions and has Tumor Therapeutic Potential in Lung …

Impaired mucociliary transport is a distinguishing sign of cystic fibrosis, but current methods of evaluation are invasive or expose young patients to ionizing radiation. Contrast-enhanced ultrasound imaging may provide a feasible alternative. We …

We present a protocol to generate a liver tumor murine model utilizing orthotopic ultrasound-guided intrahepatic injections of tumor cells and a partial hepatectomy. We describe cell and animal preparation and ultrasound-guided intrahepatic injections. We …