Implantation is a sensitive window in reproductive development during which disruptions may increase the risk of adverse pregnancy outcomes including intrauterine growth restriction. Ozone exposure during implantation in rats reduces fetal weight near the …

Recently, our group demonstrated that immobilized VEGF can capture flowing endothelial cells (ECs) fromthebloodin vitroandpromoteendothelializationandpatencyof acellular tissue–engineeredvessels (A-TEVs) into the arterial systemof an ovine animal model. …

Mast cells (MCs) have been implicated in the pathogenesis of cardiometabolic diseases by releasing pro-inflammatory mediators. Patients and animals with diabetic cardiomyopathy (DCM) also show inflammatory cell accumulation in the heart. Here we detected …

BACKGROUND Interleukin-37 (IL-37) is a new discovered member of the interleukin family and plays anti-inflammatory effect in some inflammatory disease. A recent study found that IL-37 elevated significantly in peripheral blood of patients with acute …

BACKGROUND Interleukin-37 (IL-37) is a new discovered member of the interleukin family and plays anti-inflammatory effect in some inflammatory disease. A recent study found that IL-37 elevated significantly in peripheral blood of patients with acute …

Group III Pulmonary hypertension is observed in patients chronic lung diseases such as Chronic Obstructive Pulmonary Disease (COPD) or Idiopathic Pulmonary Fibrosis (IPF). Pulmonary Hypertension (PH) develops as a result of extensive pulmonary vascular …

The presence of disseminated tumour cells (DTCs) in bone marrow is predictive of poor metastasis-free survival of patients with breast cancer with localized disease. DTCs persist in distant tissues despite systemic administration of adjuvant che- …

Gold nanoparticles have been thoroughly used in designing thermal ablative therapies and photoacoustic imaging for cancer owing to their unique and tunable plasmonic properties. While plasmonic properties highly depend on size and structure, controllable …

In the earliest phase of inflammation, histamine and other agonists rapidly mobilize P-selectin to the apical membranes of endothelial cells, where it initiates rolling adhesion of flowing neutrophils. Clustering of P-selectin in clathrin-coated pits …

Aims: This study investigated the mechanism through which fibroblast growth factor 21 (FGF21) protects against angiotensin II (Ang Ⅱ)-induced cardiac hypertrophy and dysfunction. Methods: Male silent information regulator 1 (SIRT1) flox/flox and …