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RFImageNet framework for segmentation of ultrasound images with spectra-augmented radiofrequency signals
Computer-aided segmentation of medical ultrasound images assists in medical diagnosis, promoting accuracy and reducing the burden of sonographers. However, the existing ultrasonic intelligent segmentation models are mainly based on B-mode grayscale …
Publication
Exosomal miR-155-5p promote the occurrence of carotid atherosclerosis
Periodontitis is a significant independent risk factor for atherosclerosis. Yet, the exact mechanism of action is still not fully understood. In this study, we investigated the effect of exosomes-miR-155-5p derived from periodontal endothelial cells on …
Publication
Versatile Bi2MoO6/Prussian Blue-Au nanoplatform for oxygen-self-produced and GSH-depleted enhanced sonodynamic efficacy
Deprivation of oxygen and scavenging of reactive oxygen species (ROS) severely restrict the antitumor efficiency of sonodynamic therapy (SDT). To address these challs, we report the Bi2MoO6/Prussian Blue-Au (BMO/PB-Au) nanosystem as piezoelectric …
Publication
High-frequency ultrasound for assessing the renal characteristics of spontaneous type 2 diabetes mellitus db/db mice
High-frequency ultrasound for assessing the renal characteristics of spontaneous type 2 diabetes mellitus db/db mice …
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Tuning the Fe-Gd nanoparticles co-functionalized mesoporous carbon from sphere to nanobowl for advanced bioapplications
Studies on the function-integrated nanocomposites with well-tuned morphologies have received considerable interest. Here, we reported the preparation of mesoporous carbon nanobowl integrated with stoichiometric γ-Fe2O3 and GdPO4 nanoparticles …
Publication
Ultrasound biomicroscopy in dogs suggests postoperative ocular hypertension may be associated with ciliary cleft changes related to cataract surgery
OBJECTIVE To determine whether novel pre- and postsurgical ultrasound biomicroscopy (UBM) measurements of the canine ciliary cleft (CC) are associated with postoperative ocular hypertension (POH) following cataract surgery and to explore the relationship …
Publication
CIDEC/FSP27 exacerbates obesity-related abdominal aortic aneurysm by promoting perivascular adipose tissue inflammation
Abdominal aortic aneurysm (AAA) is strongly correlated with obesity, partially due to the abnormal expansion of abdominal perivascular adipose tissue (PVAT). Cell death-inducing DNA fragmentation factor-like effector C (CIDEC), also known as fat-specific …
Publication
Novel Metal-Free Nanozyme for Targeted Imaging and Inhibition of Atherosclerosis via Macrophage Autophagy Activation to Prevent Vulnerable Plaque Formation and Rupture
Atherosclerosis is a primary cause of cardiovascular and cerebrovascular diseases, with the unpredictable rupture of vulnerable atherosclerotic plaques enriched with lipid-laden macrophages being able to lead to heart attacks and strokes. Activating …
Publication
Application of small animal ultrasound imaging technology for identification of polycystic ovary syndrome in a mouse model
Background and Aims: Polycystic ovary syndrome (PCOS) is a hormonal disorder common among women of reproductive age, characterized by irregular menstrual periods, elevated levels of androgens, and polycystic ovaries, leading to various symptoms and …
Publication
Physics-Informed Graph Neural Networks to solve 1-D equations of blood flow
Background and Objective: Computational models of hemodynamics can contribute to optimizing surgical plans, and improve our understanding of cardiovascular diseases. Recently, machine learning methods have become essential to reduce the computational cost …