PDL1 blockade therapy holds great promise in cancer immunotherapy. Ultrasound imaging of PDL1 expression in the tumor is of great importance in predicting the therapeutic efficacy. As a proof-of-concept study, a novel ultrasound contrast agent has been …

Prenatal development of autonomic innervation of sinus venosus-related structures might be related to atrial arrhythmias later in life. Most of the pioneering studies providing embryological background are conducted in animal models. To date, a detailed …

Hypertrophic cardiomyopathy (HCM) caused by autosomal-dominant mutations in genes coding for structural sarcomeric proteins, is the most common inherited heart disease. HCM is associated with myocardial hypertrophy, fibrosis and ventricular dysfunction. …

Tumor Hypoxia Assessment: In Vivo 3D Oxygen Imaging Through Electron Paramagnetic Resonance …

Corked Microcapsules Enabling Controlled Ultrasound-Mediated Protein Delivery …

GRB2 regulation of essential signaling pathways in the endometrium is critical for implantation and decidualization …

Ultrasound localization microscopy (ULM) represents a significant advancement over traditional ultra-sound (US) imaging, enabling super-resolution (SR) imaging of microvascular structures with unprecedented detail, by using microbubbles (MBs) as highly …

Atrial cardiomyocyte-restricted cleavage of gasdermin D promotes atrial arrhythmogenesis …

Cytochrome P450 family 2 subfamily E member 1 (CYP2E1) is a member of the cytochrome P450 enzyme family and catalyzes the metabolism of various substrates. CYP2E1 is upregulated in multiple heart diseases and causes damage mainly via the production of …

AIMS: Mammalian models have been instrumental in investigating adult heart function and human disease. However, electrophysiological differences with human hearts and high costs motivate the need for non-mammalian models. The zebrafish is a …