3D rendered power Doppler image of the mouse hindlimb showing blood flow. Application of a tourniquet made of tubing was used to restrict blood flow into the distal part of the limb, then relieved to allow reperfusion . …

Ultrasound (left) and photoacoustic (right) coronal images of a mouse brain post ischemia/hypoxia. The red, white and blue color represents a parametric map of oxygen saturation.  The right hemisphere does not fully recover sO 2 levels post- reperfusion …

Plot of oxygen saturation (sO 2 ) over time in the left (pink) and right (orange) cortical and subcortical hemisphere ROIs  while restoring breathed oxygen to 100% from 7.5% post ischemia/hypoxia for stroke induction.  Ultrasound (top) and photoacoustic …

3D rendered coregistered ultrasound (greyscale) and photoacoustic (red) image of the mouse ear.  The photoacoustic signal is derived from the absorption of light by …

3D rendered spectrally unmixed photoacoustic image of a stem-cell injected, ischemic (right) and control (left) mouse hindlimb. Oxyhemoglobin (red), deoxyhemoglobin (blue) and dye-labelled stem cells (green) are …

Submitted by Craig Goergen, Frederick W. Damen and Arvin H. Soepriatna of Purdue University. Through our collaboration with VisualSonics, we have developed a new protocol for collecting in vivo ECG and respiratory-gated 3D ultrasound volumes in mice in …

Currently, the only major treatment for heart failure is transplantation. However, it is estimated that less than 30% of patients survive long enough to receive their new hearts. The local cell death following myocardial infarction plays a major role in …

Submitted by Elizabeth Huynh, Dr. Zheng Lab, University of Toronto Converting nanoparticles or monomeric compounds into larger supramolecular structures by endogenous or external stimuli is increasingly popular because these materials are useful for …

Submitted by Terri A. Swanson, Senior Scientist, Comparative Medicine, Pfizer Inc. and Theresa Tuthill, Head of Cardiovascular, Metabolic, and Musculoskeletal Imaging for the Clinical and Translational Imaging group at Pfizer Inc. Terri Swanson, Theresa …

Submitted by Dr. Carlton Bates Dr. Carlton Bates heads an NIH funded research program at the University of Pittsburgh which also benefits from his clinical service as the Chief of Pediatric Nephrology. Many of the mouse models Dr. Bates has generated …