The arteriovenous fistula (AVF) is the lifeline for hemodialysis patients. However, there are currently no effective therapies promoting AVF maturation. AVF dilation by smooth muscle cell relaxation, through increased cyclic guanosine monophosphate …

Photoacoustic imaging can potentially map oxygen saturation (sO 2 ) non-invasively. However, in-vivo human application is challenging due to spectral coloring, which causes a wavelength-dependent fluence attenuation and uncertainty in the estimation of …

Noninvasive cancer imaging significantly improves diagnostics by providing comprehensive structural and functional information about tumors. Herein, we explored palladium nanoparticles loaded hafnium-based metal-organic framework (MOF) (Hf-EDB), i.e., …

Imaging technologies are constantly being developed to improve not only melanoma diagnosis, but also staging, treatment planning, and disease progression. We start with a description of how melanoma is characterized using histology, and then continue by …

Osteocalcin deficiency attenuates neointima formation after vascular injury in rat …

Immune checkpoint blockade (ICB) therapy, represented by anti-PD-1/PD-L1 antibodies, is confronted with difficulties of unsatisfied response rates owing to the prevalence of “cold” immune tumor microenvironment (TME) in most cancers. Blocking …

Background:Arterial stiffness is a key cardiovascular risk factor influenced by conditions like hypertension, obesity and kidney function. Although large arteries have been extensively studied, small conduit arteries remain less investigated. This study …

Background: Children with type 1 diabetes have an increased risk of macrovascular complications. This study used ultra-high frequency ultrasound (UHFUS), enabling differentiation of intima thickness (IT), and media thickness (MT) in peripheral arteries, …

More than 50 ​% of patients undergoing mechanical thrombectomy (MT) for ischemic stroke have a poor functional outcome despite timely and successful angiographic reperfusion, highlighting the need for adjunctive treatments to reperfusion therapy. …

Despite great promise, adoptive cell therapy (ACT) continues to fail at treating a majority of cancers, especially solid tumors. To inform development and expedite the translation of more potent cellular immunotherapies, advanced immunoimaging tools are …