OBJECTIVE: Abdominal aortic aneurysms (AAA) are an age-related vascular disease and an important cause of morbidity and mortality. In this study, we sought to determine whether the catalytic component of telomerase, telomerase reverse transcriptase …

In our previous study, we showed that treatment with an anti-interleukin (IL)-12/23p40 antibody inhibits acute cardiac allograft rejection via inhibiting production of interferon (IFN)-γ and IL-17a. However, the impact of this antagonistic anti-p40 …

In vivo 3D rendered high-resolution ultrasound image of an E14 embryo and its associated placenta (on left). … … E14 mouse embryo …

In vivo 3D rendered co-registered high-resolution ultrasound (greyscale) and photoacoustic (red) image of an E14 embryo and its associated placenta (on left). The photoacoustic signal was acquired at 750nm and represents signal from mostly deoxygenated …

In vivo 3D rendered co-registered high-resolution ultrasound (greyscale) and photoacoustic (red, white and blue) image of an E14 embryo and its associated placenta (on left). The photoacoustic signal represents a parametric map of oxygen saturation with …

In vivo 3D rendered co-registered high-resolution ultrasound (greyscale) and photoacoustic (red, white and blue) image of an E14 embryo and its associated placenta (on left). The photoacoustic signal represents a parametric map of oxygen saturation with …

In vivo high-resolution ultrasound (left) and photoacoustic (right) image of an E14 embryo and its associated placenta (on left of each image). The photoacoustic signal represents a parametric map of oxygen saturation with red values representing higher …

In vivo co-registered high-resolution ultrasound (greyscale) and photoacoustic (red, white and blue) image of an E14 embryo and its associated placenta (on left of each image). The photoacoustic signal represents a parametric map of oxygen saturation with …

3D rendered high-resolution ultrasound image of the mouse hindlimb showing a depression in the skin from a tourniquet made of tubing being used to restrict blood flow into the distal part of the limb. … … Mouse hindlimb with …

3D rendered photoacoustic image of the mouse hindlimb showing a parametric map of oxygen saturation with red denoting higher sO 2 values.  Application of a tourniquet made of tubing was used to restrict blood flow into the distal part of the limb. Much …