This study tested the hypothesis that entresto therapy effectively protected heart and lung against cardio- pulmonary syndrome (CPS) caused by transverse aortic constriction (TAC) in rat. Adult-Male SD rats (n = 36) were equally categorized into group 1 …

Background Heated tobacco products (also called ‘heat-not-burn’ products) heat tobacco at temperatures below that of combustion, causing nicotine and other compounds to aerosolise. One such product, IQOS from Philip Morris International, is being marketed …

As photoacoustic (PA) imaging makes its way into the clinic, accuracy of PA-based metrics becomes increasingly important. To address this need, a method combining finite- element-based local fluence correction (LFC) with signal-to-noise- ratio (SNR) …

Acute myocardial infarction (MI) is a leading cause of morbidity and mortality in the world. Traditional method to induce MI by left coronary artery (LCA) ligation is typi- cally performed by an invasive approach that requires ventilation and thoracotomy, …

The purpose of this study was to investigate the use of photoacoustic imaging for quantifying fingertip oxygenation as an approach to diagnosing and monitoring Raynaud's phenomenon. After 30 min of acclimation to room temperature, 22 patients (7 patients …

Platelet bio-nanobubbles as microvascular recanalization nanoformulation for acute ischemic stroke lesion theranostics …

Hemodynamic collapse and myocardial dysfunction are among the major causes of death in severe sepsis. The purpose of this study was to assess the role played by TLR4 and by the NLRP3 inflammasome in the cardiac dysfunction that occurs after high-grade …

Mitochondrial damage is involved in the pathogenesis of post-infarction cardiac injury. However, the upstream regulators of mitochondrial damage have not yet been identified. The aim of our study is to explore the role of Sirt3 in post-infarction cardiac …

OBJECTIVE: We investigate the effect of long non-coding RNA H19 in acute myo- cardial infarction (AMI) and the underlying mech- anism. MATERIALS AND METHODS: C57BL/6 mice were subjected to AMI and injected with lenti- virus pcDNA-H19. After AMI procedures …

Omega-3 polyunsaturated fatty acid (n-3 PUFA) supplementation is a recommended preventive approach against cardiovascular diseases, but its mechanism of protection against myocardial infarction (MI) injury is not fully understood. Eicosanoid metabolomics …