In this parametric map of oxygen saturation in an orthotopic breast tumor, the breathed oxygen concentration is varied from 100% to 5% back to 100% and the resulting changes in sO₂ can be observed in different areas.

Note that the sO₂ in the tumor interior does not change appreciably during the breathed oxygen challenge, indicating impaired function of the vasculature there.

3D rendered coregistered ultrasound (greyscale) and photoacoustic (red) image of the mouse ear.  The photoacoustic signal is derived from the absorption of light by hemoglobin.

Non-linear contrast bolus perfusion into a subcutaneous tumor in a mouse. See Oncology images.

Co-registered 3D rendered ultrasound (greyscale) and color Doppler (red and blue) coronal image of a mouse brain during ligation of the right common carotid artery.  The red and blue color represent blood flow velocity and direction clearly showing impaired blood flow in the right hemisphere.

3D rendered photoacoustic image showing cerebral blood signal in the mouse brain.

3D rendered co-registered ultrasound (greyscale) and photoacoustic (red, white and teal) image showing a parametric map of oxygen saturation with red signals indicating higher sO₂ values.

3D rendered high-resolution ultrasound (greyscale) and spectrally unmixed photoacoustic (red, blue and gold) image of a subcutaneous tumor showing nanoparticle distribution (yellow) as well as oxygenated (red) and deoxygenated (blue) hemoglobin signal.

High-resolution ultrasound (greyscale) and photoacoustic (red, white and blue) image of a long axis view of the left ventricle of the mouse heart. The photoacoustic image is a parametric map of oxygen saturation in the myocardium.