Developmental
Studying mouse and rat embryos has never been easier
In Vivo Developmental and Pregnancy Research at any Gestational Time Point
From detecting pregnancy to measuring fetal and placental oxygenation and blood flow; the Vevo can do it all!
Vevo micro-ultrasound imaging platforms are ideally suited for developmental and pregnancy research in small animals. The size, structural details and function of the placenta and developing embryo can all be measured over multiple gestational time-points without having to sacrifice your animal.
Repeatable for longitudinal studies over gestation, rapid, and robust and with resolution down to 30 μm, studying mouse and rat embryos has never been easier.
- Detect and date pregnancy with confidence
- Measure size, blood flow and oxygen saturation in the placenta
- Visualize and measure umbilical blood flow
- Visualize and study fetal organ development
- Measure developing heart contractility and blood vessel flow
- Image-guided embryo injection

Mouse Implantation Site at Mid-Gestation

Spiral Arteries with Color Doppler in a Mid-Gestational Mouse Placenta

Mouse Umbilical Artery Flow at Mid-Gestation

Mouse embryo and placenta showing oxygenation, using photoacoustic imaging.
Ideal For Research on:
- Developmental toxicity and drug trials
- Fetal programming
- Pregnancy research and pregnancy complications
Displaying 1 - 5 of 182 results found
Top Paper
A Protocol for Evaluating Vital Signs and Maternal-Fetal Parameters Using High-Resolution Ultrasound in Pregnant Mice
Jose Galaz, Roberto Romero, Marcia Arenas-Hernandez, Bogdan Panaitescu, Valeria Garcia-Flores, Nardhy Gomez-Lopez
STAR Protocols
.2021
;Top Paper
Placenta-specific drug delivery by trophoblast-targeted nanoparticles in mice
Baozhen Zhang, Lunbo Tan, Yan Yu, Baobei Wang, Zhilong Chen, Jinyu Han, Mengxia Li
Theranostics
.2018
;Maternal B cell signaling orchestrates fetal development in mice
Mandy Busse, Stefanie Langwisch, Kerry Tedford, Klaus-Dieter Fischer, Ana Claudia Zenclussen
Development
.2022
;Echocardiographic assessment of fetal cardiac function in the uterine artery ligation rat model of IUGR
Yichen Dai, Dan Zhao, Ching Kit Chen, Choon Hwai Yap
Pediatric Research
.2021
;Adverse maternal and fetal outcomes in a novel experimental model of pregnancy after recovery from renal ischemia-reperfusion injury
Ellen E. Gillis, Michael W. Brands, Jennifer C. Sullivan
Journal of the American Society of Nephrology
.2021
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Can uterine spiral arteries be visualized and measured in the mouse?
Yes! This is an advanced technique...
What is the best way to find the uterine artery for PW Doppler measurements?
The uterine artery can be located...
Can embryo staging be performed using the Vevo ultrasound system? What’s the earliest you can see embryos in a mouse using ultrasound?
Yes, embryo staging can be done throughout pregnancy and the pregnancy can be detected as early as gd 0.5...