Background-—Macrophages and Wnt proteins (Wnts) are independently involved in cardiac development, response to cardiac injury, and repair. However, the role of macrophage-derived Wnts in the healing and repair of myocardial infarction (MI) is unknown. We …

Color Doppler image of the aortic arch in a mouse following transaortic constriction. … … Aortic Arch Following Transaortic Constriction …

The etiology of benign prostatic hyperplasia (BPH) is multifactorial, and chronic inflammation plays a pivotal role in its pathogenesis. Growth hormone-releasing hormone (GHRH) is a hypothalamic neuropeptide that has been shown to act as …

Chronic ventricular pressure overload (PO) results in congestive heart failure (CHF) in which myocardial fibrosis develops in concert with ventricular dysfunction. Caveolin-1 is important in fibrosis in various tissues due to its decreased expression in …

Ultrasonography is a powerful tool to non-invasively monitor in real time the development of the human fetus in utero. Although genetically engineered mice have served as valuable in vivo models to study both embryo implantation and pregnancy progression, …

Background Although cardiac and splenic mononuclear phagocytes (MPs), i.e., monocytes, macro- phages and dendritic cells (DCs), are key contributors to cardiac remodeling after myo- cardial infarction, their role in pressure-overload remodeling is …

Sleep apnea, which is the periodic cessation of breathing during sleep, is a major health problem affecting over 10 million people in the United States and is associated with several sequelae, in- cluding hypertension and stroke. Clinical studies suggest …

4D image of the mouse left ventricle acquired from a parasternal short axis view. A 4D volume was drawn and can be visualized in red. … … 4D Left Ventricular Volume …

High-frequency ultrasound (~20 MHz) techniques were investigated using in vitro and ex vivo models to determine whether alterations in chromatin structure are responsible for ultrasound backscatter changes in biological samples. Acute myeloid leukemia …

The present study focuses on the identification of the gene expression profile of neonatal rat cardiomyocytes (NRVCMs) after dynamic mechanical stretch through microarrays of RNA isolated fromcells stretched for 2, 6 or 24 h. In this analysis,myeloid …