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CardiologyQuantify cardiac function and structure non-invasively and in real-time!
Your Best Tool For Mouse Echocardiography
Rapid, Repeatable and Well-Established; Ultra High Frequency ultrasound, using the Vevo Imaging Systems, will have an incredible impact on cardiovascular research in your animal models.
Perform reliable echocardiography in mice and other small animals for translational cardiovascular research with in vivo resolution down to 30 microns. Vevo ultrasound imaging platforms provide the best temporal and spatial resolution compared to MRI, conventional ultrasound and CT.
With the Vevo Imaging Systems you can:
- Perform cardiovascular phenotyping for cardiac structure and function
- Image the heart in 4D!
- Quantify diastolic dysfunction
- Evaluate cardiac strain (synchrony and deformation globally or regionally)
- Perform image-guided cardiac injections
- Monitor full animal physiology while imaging: body temperature, ECG and respiratory rate throughout the imaging session.
- Ideal for stress echo and cardiotoxicity studies.
- Assess myocardial oxygen saturation
Mouse left ventricle imaged with 4D Mode from a parasternal long axis view.
Standard mouse echocardiography. Left Ventricular measurements taken from a B-Mode parasternal long axis image.
Mitral flow visualized from an apical view of the mouse left ventricle to assess diastolic function.
B-Mode ultrasound with myocardial oxygen saturation acquired using photoacoustics (PA EKV Mode), from a parasternal long axis view of the mouse left ventricle.
Use Vevo Echocardiography to Image any Cardiac Disease Model, Including:
- Myocardial Infarction
- Valvular Disease
- Cardiac Hypertrophy
Downloaded or access resources related to Your Best Tool For Mouse Echocardiography
Caveolin-1 deficiency exacerbates cardiac dysfunction and reduces survival in mice with myocardial infarction.
PITX2c is expressed in the adult left atrium, and reducing Pitx2c expression promotes atrial fibrillation inducibility and complex changes in gene expression.
CC chemokine receptor 5 deletion impairs macrophage activation and induces adverse remodeling following myocardial infarction
Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice.
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Watch the full video.
"The Vevo ultra high frequency ultrasound systems and linear array transducers are perfect for fast, high resolution imaging. The Vevo is extremely easy to use and the image quality is fantastic, opening up numerous biomedical applications we are only now beginning to explore."
-Craig J. Goergen, PhD
Leslie A. Geddes Associate Professor of Biomedical Engineering, Weldon School of Biomedical Engineering, Purdue University
Watch this in-depth interview with Dr. Craig Goergen: