In vivo high-resolution ultrasound (left) and photoacoustic (right) image of an E14 embryo and its associated placenta (on left of each image). The photoacoustic signal represents a parametric map of oxygen saturation with red values representing higher …

In vivo co-registered high-resolution ultrasound (greyscale) and photoacoustic (red, white and blue) image of an E14 embryo and its associated placenta (on left of each image). The photoacoustic signal represents a parametric map of oxygen saturation with …

3D rendered photoacoustic image of the mouse hindlimb showing a parametric map of oxygen saturation with red denoting higher sO 2 values.  Application of a tourniquet made of tubing was used to restrict blood flow into the distal part of the limb. Much …

3D rendered photoacoustic image of the mouse hindlimb showing a parametric map of oxygen saturation with red denoting higher sO 2 values.  Application of a tourniquet made of tubing was used to restrict blood flow into the distal part of the limb, then …

3D rendered power Doppler image of the mouse hindlimb showing blood flow. Application of a tourniquet made of tubing was used to restrict blood flow into the distal part of the limb, then relieved to allow reperfusion . …

Ultrasound (left) and photoacoustic (right) coronal images of a mouse brain post ischemia/hypoxia. The red, white and blue color represents a parametric map of oxygen saturation.  The right hemisphere does not fully recover sO 2 levels post- reperfusion …

Plot of oxygen saturation (sO 2 ) over time in the left (pink) and right (orange) cortical and subcortical hemisphere ROIs  while restoring breathed oxygen to 100% from 7.5% post ischemia/hypoxia for stroke induction.  Ultrasound (top) and photoacoustic …

3D rendered coregistered ultrasound (greyscale) and photoacoustic (red) image of the mouse ear.  The photoacoustic signal is derived from the absorption of light by …

3D rendered spectrally unmixed photoacoustic image of a stem-cell injected, ischemic (right) and control (left) mouse hindlimb. Oxyhemoglobin (red), deoxyhemoglobin (blue) and dye-labelled stem cells (green) are …

Submitted by Craig Goergen, Frederick W. Damen and Arvin H. Soepriatna of Purdue University. Through our collaboration with VisualSonics, we have developed a new protocol for collecting in vivo ECG and respiratory-gated 3D ultrasound volumes in mice in …