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Treatment with selumetinib preserves cardiac function and improves survival in cardiomyopathy caused by mutation in the lamin A/C gene.
Cardiovascular research
, Loss of hypoxia-inducible factor prolyl hydroxylase activity in cardiomyocytes phenocopies ischemic cardiomyopathy.
Circulation
, Spontaneous adult-onset pulmonary arterial hypertension attributable to increased endothelial oxidative stress in a murine model of hereditary hemorrhagic telangiectasia.
Arteriosclerosis, thrombosis, and vascular biology
, Adiponectin deficiency: a model of pulmonary hypertension associated with pulmonary vascular disease
American Journal of Physiology-Lung Cellular and Molecular Physiology
, Validation of high-resolution echocardiography and magnetic resonance imaging vs. high-fidelity catheterization in experimental pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology
, Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure.
Circulation
, The critical roles of platelet activation and reduced NO bioavailability in fatal pulmonary arterial hypertension in a murine hemolysis model
Blood
, Dehydroepiandrosterone restores right ventricular structure and function in rats with severe pulmonary arterial hypertension.
American journal of physiology. Heart and circulatory physiology
, Estrogen rescues preexisting severe pulmonary hypertension in rats.
American journal of respiratory and critical care medicine
, Noninvasive assessment of murine pulmonary arterial pressure: validation and application to models of pulmonary hypertension.
Circulation. Cardiovascular imaging
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