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Inactivation of Plin4 downregulates Plin5 and reduces cardiac lipid accumulation in mice.
American journal of physiology. Endocrinology and metabolism
, Cardiac-specific deletion of the microtubule-binding protein CENP-F causes dilated cardiomyopathy.
Disease models & mechanisms
, Agonist-independent constitutive activity of angiotensin II receptor promotes cardiac remodeling in mice.
Hypertension
, Sustained hemodynamic stress disrupts normal circadian rhythms in calcineurin-dependent signaling and protein phosphorylation in the heart.
Circulation research
, Timing of myocardial trpm7 deletion during cardiogenesis variably disrupts adult ventricular function, conduction, and repolarization.
Circulation
, TBX5 drives Scn5a expression to regulate cardiac conduction system function
Journal of Clinical Investigation
, Ryanodine receptor type 2 is required for the development of pressure overload-induced cardiac hypertrophy.
Hypertension
, Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice.
Circulation
, Cardiomyocyte-specific loss of neurofibromin promotes cardiac hypertrophy and dysfunction.
Circulation research
, Cardiac response to pressure overload in 129S1/SvImJ and C57BL/6J mice: temporal- and background-dependent development of concentric left ventricular hypertrophy
American Journal of Physiology - Heart and Circulatory Physiology
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