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Chronic creatine kinase deficiency eventually leads to congestive heart failure, but severity is dependent on genetic background, gender and age.
Basic research in cardiology
, Ginseng Inhibits Cardiomyocyte Hypertrophy and Heart Failure via NHE-1 Inhibition and Attenuation of Calcineurin Activation
Circulation: Heart Failure
, NF-kappaB activation is required for adaptive cardiac hypertrophy.
Cardiovascular research
, Alpha B-crystallin suppresses pressure overload cardiac hypertrophy.
Circulation research
, Effects of nicotine administration in a mouse model of familial hypertrophic cardiomyopathy, α-tropomyosin D175N.
American journal of physiology. Heart and circulatory physiology
, Impact of high-fat diet on antioxidant status, vascular wall thickening and cardiac function in adult female LDLR<sup>–/–</sup> mice
World Journal of Cardiovascular Diseases
, Endothelial expression of hypoxia-inducible factor 1 protects the murine heart and aorta from pressure overload by suppression of TGF-β signaling.
Proceedings of the National Academy of Sciences of the United States of America
, Locally applied leptin induces regional aortic wall degeneration preceding aneurysm formation in apolipoprotein E-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology
, APPL1 transgenic mice are protected from high-fat diet-induced cardiac dysfunction.
American journal of physiology. Endocrinology and metabolism
, Cardiac sympathetic neurons provide trophic signal to the heart via 2-adrenoceptor-dependent regulation of proteolysis
Cardiovascular Research
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