Can I measure pulse wave velocity (pulse propagation velocity) using your system?

Yes, pulse propagation velocity (PPV) can be measured using our Vevo Vasc software. There is also a more manual approach to measuring PPV using a B-Mode image of a vessel and PW Doppler samples from either end of the vessel. Details on the more automated Vevo Vasc approach can be found in our Vevo Vasc User Guide.

For PPV measurements using the manual transit time method, you will need to acquire 3 sets of images. 2 PW Doppler clips of the vessel, one at a proximal location, and another at a distal location. These will be used for the time measurements. You will also need 1 B-mode image of the vessel, encompassing the two spots where the PW Doppler data was acquired. This will be used to measure the distance between the two locations (see diagram below).

Further information and details on the manual approach can be found in several publications1.

1. Williams, R., Needles, A., Cherin, E., Zhou, Y.-Q., Henkelman, R. M., Adamson, S. L., & Foster, F. S. (2007). Noninvasive ultrasonic measurement of regional and local pulse-wave velocity in mice. Ultrasound in Medicine & Biology, 33(9), 1368–75. http://doi.org/10.1016/j.ultrasmedbio.2007.03.012