Photoacoustic Imaging of Neurovascular Oxygenation in Cardiovascular Disease Models: From Anesthetized to Awake Mice presented by Dr. Pierre Sicard, Plateforme IPAM/Biocampus (IBiSa / France Life Imaging), France
Dr. Pierre Sicard presented photoacoustic and ultrasound for assessing the link between heart and brain as well as for traumatic brain injury models. Big focus was on brain oxygenation in 2D (dynamic, real-time) and 3D (whole brain). He highlighted the advantages of PAUS imaging over traditional methods such as MRI, particularly in cost, resolution, and ability to perform longitudinal studies. His talk included the world’s first data of visualizing brain activity in fully conscious mice using the Vevo platform. He showcased sensitive detection of cerebral blood flow changes, oxygen saturation, and vascular remodeling, highlighting the Vevo for imaging the rodent brain.