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Overexpression of the SK3 channel alters vascular remodeling during pregnancy, leading to fetal demise.
American journal of physiology. Endocrinology and metabolism
, Ablation of Nkx2-5 at mid-embryonic stage results in premature lethality and cardiac malformation.
Cardiovascular research
, Fgl2 deficiency causes neonatal death and cardiac dysfunction during embryonic and postnatal development in mice.
Physiological genomics
, Embryonic and neonatal phenotyping of genetically engineered mice.
ILAR journal / National Research Council, Institute of Laboratory Animal Resources
, Tbx20 acts upstream of Wnt signaling to regulate endocardial cushion formation and valve remodeling during mouse cardiogenesis.
Development (Cambridge, England)
, Tafazzin knockdown in mice leads to a developmental cardiomyopathy with early diastolic dysfunction preceding myocardial noncompaction.
Journal of the American Heart Association
, Inactivation of Plin4 downregulates Plin5 and reduces cardiac lipid accumulation in mice.
American journal of physiology. Endocrinology and metabolism
, Cardiac-specific deletion of the microtubule-binding protein CENP-F causes dilated cardiomyopathy.
Disease models & mechanisms
, Agonist-independent constitutive activity of angiotensin II receptor promotes cardiac remodeling in mice.
Hypertension
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