Vascular Biology
Preclinical Ultrasound for Vascular Biology Research
Visualize and Quantify Vascular Function
Ultra-high Frequency (UHF) Vevo imaging systems allow for non-invasive, real-time evaluation of vascular function with resolution down to 30 microns.
With UHF imaging and software, you can:
- Quantify pulse wave velocity and vascular resistance
- Detect aneurysm and plaque formation with 3D reconstruction
- Analyze vessel wall characteristics (i.e. diameter, strain, velocity, stiffness, etc.)
- Quantify blood flow and perfusion
Perfect for Animal Models of:
- Atherosclerosis
- Aneurysm
- Arteriosclerosis
- Vascular Ischemia
Vascular Biology
Right Femoral Artery Bifurcation in a Mouse
Gallery
Abdominal Aorta Used In Strain Analysis
B-mode image of the abdominal aorta with vessel wall velocity vector arrows used in strain analysis.
M-Mode of a Mouse Carotid Artery
M-mode image of mouse left common carotid.
Measurements: wall thickness and vessel diameter in systole and diastole.
Splenic Vasculature in a Mouse
Murine Renal Vasculature in 3D
3D Spleen and Kidney Vasculature
3D Power Doppler rendering of a mouse spleen and kidney, highlighting splenic and renal vasculature.
Blood flow in tumor
3D rendered high-resolution ultrasound (greyscale) and color Doppler (orange and blue) image of a subcutaneous tumor showing blood flow.
Blood flow in tumor
Blood flow in tumor
3D rendered high-resolution ultrasound (greyscale) and color Doppler (orange and blue) image of a subcutaneous tumor showing blood flow.
Publications
PGC1α regulates the mitochondrial metabolism response to cyclic stretch, which inhibits neointimal hyperplasia
Cellular and Molecular Life Sciences
, Histone deacetylase 9-mediated phenotypic transformation of vascular smooth muscle cells is a potential target for treating aortic aneurysm/dissection
Biomedicine and Pharmacotherapy
, Controllable Thrombolysis Using a Nanobubble-Imaging-Guided rtPA Targeted Delivery Strategy
BME Frontiers
, Angiotoxic effects of chlorinated polyfluorinated ether sulfonate, a novel perfluorooctane sulfonate substitute, in vivo and in vitro
Journal of Hazardous Materials
, Adaptor protein HIP-55 promotes macrophage M1 polarization through promoting AP-1 complex activation
Cellular Signalling
, Allograft Model of Aortic Arch Segment Grafting to Abdominal Aorta Through End-to-Side Anastomosis in Mice
Journal of Cardiovascular Translational Research
, Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence
Nature Communications
, Exercise mitigates flow recirculation and activates metabolic transducer SCD1 to catalyze vascular protective metabolites
Sci. Adv
, Distinct cellular microenvironment with cytotypic effects regulates orderly regeneration of vascular tissues
Materials Today Bio
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