Vevo News: Issue 9 - September 2015
Multimodality Imaging Using Vevo Technology Offers Complementary Data For Best Possible Answers 
During the month of September we focused on Multimodality Imaging at FUJIFILM VisualSonics. It all started in Honolulu at the World Molecular Imaging Conference (WIMIC) from September 2-5. This meeting brought together the leading imaging scientists from across the world to discuss the latest advances in Molecular Imaging. The full range of imaging modalities were represented in the sessions, posters and exhibits, which included FUJIFILM VisualSonics’ micro-ultrasound (Vevo 3100) and photoacoustics technology (Vevo LAZR). 



At WMIC, numerous presentations included data collected from various imaging techniques, generally in a complementary fashion. The use of ultrasound and photoacoustics played a vital role in many of these studies. By nature, they are inherently complementary, not only with each other but with the other modalities as well. This prompted us to follow-up WMIC with a Multimodality Imaging Webinar  to highlight studies that used ultrasound and photoacoustics in combination with other imaging techniques. In some cases, these studies used the complementary modalities for validation of a particular method, such as Rich et. al that conducted a study validating oxygenation measurements made with photoacoustics with BOLD MRI. Other studies highlighted the complementary aspects where multiple levels of information were obtained using multiple imaging systems. An example is the study from Avan et al. which demonstrated the advantages of the use of ultrasound, MRI and bioluminescence combined in a mouse model of pancreatic carcinoma. During the webinar we also made mention of the fact that the Vevo LAZR platform, in and of itself, is multimodal as it brings together both ultrasound and photoacoustics; two distinct yet related imaging technologies.

For users of the Vevo Imaging Systems, we want to support your use of different techniques to help further your research, because we know that each imaging modality has its strengths. Combining techniques may give the fullest picture and richest data. To help facilitate this, we have recently partnered with inviCRO to develop VisualSonics iPACS, a web-based resource designed for imaging labs sharing and organizing data across multiple imaging modalities.  inviCRO is very much aware of the importance of picking the right imaging solution for the right application. This point is clearly evident in a recent Science article on small animal imaging to which I have contributed. Click here to read. In the final paragraph of the article, Dr. Lihong Wang sums it up nicely with this quote (condensed): “Different imaging methods exploit different contrast mechanisms and thus complement one another. This is why you don’t want to say one technology will replace the rest. I’ve found that never really happens, not in the medical-imaging world.”

-  Andrew Needles, Senior Manager, Product Innovation
Multimodal Imaging And The Newest Cancer Theranostic Agent

Shared by Dr. Peng Huang (the latest winner in our 2015 Vevo Young Investigator awards competition presented at WMIC 2015, Honolulu, Hawaii. See photo below).
From Left to Right: Andrew Heinmiller, Dr. Peng Huang, Daniel Meng, Andrew Needles

Dr. Peng Huang presented his work on the development of a clinically translatable cancer theranostic agent at the World Molecular Imaging Conference in Hawaii. This therapy uses a near-infrared (NIR) cyanine dye and human serum albumin (HSA) conjugate for NIRfluorescence/photoacoustic/thermal multimodality imaging and photothermal tumor ablation. This work was supported by the Intramural Research Program (IRP) of the National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH). Click here to read Dr. Peng Huang's complete bio.


Click here to learn more about theranostic agent development, published in ACS Nano. 
Multimodal Imaging Of Bacterial Infection
Bacterial infection is a major cause of morbidity and mortality, especially in the case of antibiotic-resistant strains of S. aureus.   A small animal model that uses noninvasive imaging provides a valuable system to study pathogenesis, its treatments and diagnostic approaches. Click here to see enlarged image with full story.
NEW! Vevo AppsTalk
Every month in this new segment, one of our own Applications Scientists will share a favorite trick for image acquisition or analysis.
This month, Kristiina explains Left Lateral Decubitus Position:

Although you would originally assume that echocardiography would be easier in rat than in mouse, anyone who has done both will quickly acknowledge that the former is actually more challenging. Despite the larger size of the rat heart, ultrasound scanning is more difficult due to increased skin thickness, increased lung artifact and the increased shifting of lung and heart within the thorax. These challenges are typically worsened for larger rats. Click here to read more. 
Only One More Travel Award Left In 2015!
One more travel award left! Click here to submit your abstracts on cardiovascular research. Deadline, October 12th.

Coming Soon! 2016 Call for Abstracts - Cancer Track!
Miss Our September Webinar On Multimodal Imaging? 
Don't worry if you missed our September webinar. Here's your chance to catch up. Our very own Dieter Fuchs and Andrew Heinmiller gave an engaging presentation on multimodal imaging last week.

UPCOMING WEBINARS:

Clinically Translatable Cancer Research with Ultrasound Guided Photoacoustic Imaging

Oct 14 2015 - 1:00pm Eastern
Speaker:Dr. Srivalleesha Mallidi, Research Fellow. Harvard Medical School, Wellmann Cetner for Photomedicine, Boston
 
Cardiac and Respiratory-Gated 3D Ultrasound Imaging

Nov 18 2015 - 1:00pm Eastern
Speaker:Arvin Soepriatna and Dr. Craig Goergen. Weldon School of Biomedical Engineering, Purdue University, Indiana
Upcoming Events

Oct 11-14, 2015 The 7th EMT (Epithelial-Mesenchymal Transition) International Meeting TEMTIA-VII The Pullman Albert Park Melbourne, Victoria, Australia
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Oct 17-21, 2015 SFN 
McCormick Place Convention Center, Chicago, IL
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Orange County Convention Center, Orlando, FL
FUJIFILM VisualSonics, Inc., 3080 Yonge Str, Suite 6100 Toronto, ON, M4N 3N1, Canada
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