Generation of Pancreatic Organoid-Derived Isografts

Sabrina D’Agosto, Francesca Lupo, Vincenzo Corbo
STAR Protocols2020
This protocol is a procedure for generating orthotopic isografts using mouse pancreatic cancer organoids. These isografts can be used to track the evolution of pancreatic ductal adenocarcinoma (PDA) from a preinvasive lesion to a met- astatic disease and therefore represent a suitable model for identification of de- terminants of PDA progression.

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