Neurobiology
Functional real-time brain imaging
See the Whole Mouse Brain in Vivo and in Real-time with Neuroimaging
Visualize anatomy and functional processes for your small animal neuroscience research including stroke, cancer and in vivo delivery of drugs, stem cells, or other agents.
There are many neuroimaging techniques for preclinical studies, however these can suffer from limitations in resolution, insufficient depth, the use of ionizing radiation or expense. High frequency ultrasound and photoacoustic imaging circumvents these limitations by offering a non-invasive, real-time high resolution technique which is capable of assessing many neurologically relevant parameters in 2D and 3D such as:
- Blood flow
- Perfusion
- Oxygen saturation
- Total Hemoglobin
- Contrast agents (dyes, nanoparticles)
In addition, the Vevo BRAIN stereotactic frame and neuroanatomical atlas facilitates mouse brain imaging for increased ease-of-use and reproducibility.
See Resources tab to view webinars on ultrasound and photoacoustic imaging of the mouse brain and explore neurobiology applications such as:
- Stroke
- Brain cancer
- Contrast agent imaging
- Ultrasound-guided intracranial injections
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A cerebellar window for intravital imaging of normal and disease states in mice
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Use of high-frequency ultrasound to study the prenatal development of cranial neural tube defects and hydrocephalus in Gldc -deficient mice
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Drew Heinmiller discusses Photoacoustics at SFN 2017: