DevelopmentalStudying mouse and rat embryos has never been easier
In Vivo Developmental and Pregnancy Research at any Gestational Time Point
From detecting pregnancy to measuring fetal and placental oxygenation and blood flow; the Vevo can do it all!
Vevo micro-ultrasound imaging platforms are ideally suited for developmental and pregnancy research in small animals. The size, structural details and function of the placenta and developing embryo can all be measured over multiple gestational time-points without having to sacrifice your animal.
Repeatable for longitudinal studies over gestation, rapid, and robust and with resolution down to 30 μm, studying mouse and rat embryos has never been easier.
- Detect and date pregnancy with confidence
- Measure size, blood flow and oxygen saturation in the placenta
- Visualize and measure umbilical blood flow
- Visualize and study fetal organ development
- Measure developing heart contractility and blood vessel flow
- Image-guided embryo injection
Mouse Implantation Site at Mid-Gestation
Spiral Arteries with Color Doppler in a Mid-Gestational Mouse Placenta
Mouse Umbilical Artery Flow at Mid-Gestation
Mouse embryo and placenta showing oxygenation, using photoacoustic imaging.
Ideal For Research on:
- Developmental toxicity and drug trials
- Fetal programming
- Pregnancy research and pregnancy complications
Mutation of LRP1 in cardiac neural crest cells causes congenital heart defects by perturbing outflow lengthening
BOLD-MRI demonstrates acute placental and fetal organ hypoperfusion with fetal brain sparing in response to phenylephrine but not ephedrine
Intrauterine exposure to chronic hypoxia in the rat leads to progressive diastolic function and increased aortic stiffness from early postnatal developmental stages
Dermal exposure to the UV filter benzophenone-3 during early pregnancy affects fetal growth and sex ratio of the progeny in mice
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