CardiologyQuantify cardiac function and structure non-invasively and in real-time!
Your Best Tool For Mouse Echocardiography
Rapid, Repeatable and Well-Established; Ultra High Frequency ultrasound, using the Vevo Imaging Systems, will have an incredible impact on cardiovascular research in your animal models.
Perform reliable echocardiography in mice and other small animals for translational cardiovascular research with in vivo resolution down to 30 microns. Vevo ultrasound imaging platforms provide the best temporal and spatial resolution compared to MRI, conventional ultrasound and CT.
With the Vevo Imaging Systems you can:
- Perform cardiovascular phenotyping for cardiac structure and function
- Image the heart in 4D!
- Quantify diastolic dysfunction
- Evaluate cardiac strain (synchrony and deformation globally or regionally)
- Perform image-guided cardiac injections
- Monitor full animal physiology while imaging: body temperature, ECG and respiratory rate throughout the imaging session.
- Ideal for stress echo and cardiotoxicity studies.
- Assess myocardial oxygen saturation
Mouse left ventricle imaged with 4D Mode from a parasternal long axis view.
Standard mouse echocardiography. Left Ventricular measurements taken from a B-Mode parasternal long axis image.
Mitral flow visualized from an apical view of the mouse left ventricle to assess diastolic function.
B-Mode ultrasound with myocardial oxygen saturation acquired using photoacoustics (PA EKV Mode), from a parasternal long axis view of the mouse left ventricle.
Use Vevo Echocardiography to Image any Cardiac Disease Model, Including:
- Myocardial Infarction
- Valvular Disease
- Cardiac Hypertrophy
Downloaded or access resources related to Your Best Tool For Mouse Echocardiography
Echocardiographic Strain Analysis for the Early Detection of Left Ventricular Systolic/Diastolic Dysfunction and Dyssynchrony in a Mouse Model of Physiological Aging
AT1 receptor blocker inhibits HMGB1 expression in pressure overload-induced acute cardiac dysfunction by suppressing the MAPK/NF-κB signaling pathway
Mitochondria damage in ambient particulate matter induced cardiotoxicity: Roles of PPAR alpha/PGC-1 alpha signaling
Kanglexin protects against cardiac fibrosis and dysfunction in mice by TGF-β1/ERK1/2 noncanonical pathway
SH2 domain-containing protein tyrosine phosphatase-2 (SHP-2) prevents cardiac remodeling after myocardial infarction through ERK/SMAD signaling pathway
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Why are the values for Fractional Shortening (FS) different between analysis in M-Mode and B-Mode?
Is it possible to do strain analysis on EKV (ECG-gated Kilohertz Visualization) images?
Is it possible to measure diastolic strain?
What type of ECG signal is provided by the Vevo system?
Will AutoLV work without ECG input? Is there a workaround if there is no ECG data available?
Do you have baseline “normal” echo values for various mouse/rat models?
Why am I not able to visualize both E peak and A peak in mitral PW Doppler?
What formulas are used to calculate volume for Ejection fraction and other values in a long axis B-mode LV trace vs. short axis M-mode LV trace? Which formula is best?
Where would I be able to find the formulas used for the calculation of various echo parameters?
Why are values for systolic function different between LV long axis and LV short axis M-mode images? Which image should I use to calculate LV systolic function?
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Watch the full video.
"The Vevo ultra high frequency ultrasound systems and linear array transducers are perfect for fast, high resolution imaging. The Vevo is extremely easy to use and the image quality is fantastic, opening up numerous biomedical applications we are only now beginning to explore."
-Craig J. Goergen, PhD
Leslie A. Geddes Associate Professor of Biomedical Engineering, Weldon School of Biomedical Engineering, Purdue University
Watch this in-depth interview with Dr. Craig Goergen: