Vevo News: Issue 3 - March 2015
Tackling the Challenges of Translational Research 
By Dr. Minalini Lakshman, Applications Marketing Manager

2015 is pushing the frontiers of disease research in the context of translating discoveries for clinical  utility. Scientists, like you, continue to contribute to this context with over 1000 publications over the last decade. Thank you!

Today’s research demands the study in relevant models that recapitulates human disease with a focus on tissue microenvironment and its remodelling. At VisualSonics, we are motivated to bring the right research tools on the Vevo Imaging Systems to empower you with solutions towards today’s challenges in translational research.  Imaging biological events of translational value demands acquisition and quantitation in multiple dimensions and at depths. Image fusion satisfies this demand. Imaging on the Vevo systems gives you 5 data sets in 3 dimensions from 1 scan. Click here for an illustration.

2015 conference season is in full swing! Meet the VisualSonics team to continue your education on ultrasound and photoacoustic imaging of in vivo models of human diseases and therapy discoveries. Your continuing education is supported by a multitude of digital and traditional programs such as the VSI University Courses, On-site Training support, Workshops and Webinars. VevoNews, Vevo Blog and ‘In the Spotlight’ are your resources to the current news and views within the Vevo Research community.

At this time, we remind you of our support to your career in translational research with the launch of the Young Investigator Award. Learn more about this program to support research on Cardiovascular, Cancer, Neurobiology and Molecular Imaging.

In 2015 and with you, we are Bringing Discoveries to Patients.

Best wishes – Dr. Minalini Lakshman, Applications Marketing Manager

Predicting Tumor Recurrence Using Vevo LAZR 
Submitted by Srivalleesha Mallidi, Ph.D., Research Fellow, Harvard Medical School, Wellman Center for Photomedicine, Boston, MA, USA
The unique feature of obtaining tumor structure and functional properties using the Vevo LAZR system enabled us to monitor therapies such as photodynamic therapy and predict tumor recurrence. By precisely monitoring the change in oxygen saturation within the 3D tumor volume, we could predict regions that did not have sufficient therapeutic effect and hence recurred at later time point. Information on the likelihood of tumor regrowth that normally would have been available only upon actual regrowth (10-30 days post treatment) in xenograft tumor model, was available within 24-hrs of treatment using PAI, thus making early intervention a possibility. We hope to extend this technique  to guide and monitor various cancer targeted therapies. This work is recently published in Theranostics and was chosen for the cover feature.
Vevo LAZR makes the cover of Theranostics
Image of the Month : "In this study we show that mapping the change in blood oxygen saturation (StO2) with photodynamic therapy (PDT) within the 3D tumor volume could act as a surrogate marker to predict the likelihood of PDT success..."
 
Heading to AACR 2015? Visit us at Booth #2012!


We invite you to our Customer Appreciation & Awards Night on Monday,April 20th from 6:30 pm to 9:30pm at the Ritz Carlton. RSVP today to reserve your spot as spaces are limited.
During the conference, we will be hosting two in-booth presentations. Session dates: Monday,April 20th and Tuesday,April 21st at 2pm at Booth #2012.
Please register to attend to be eligible to win a prize giveaway.
TECH TALK: Vevo LAB Software Upgrade Available

Vevo® LAB software offers advanced tools for quantifying and characterizing indicators of disease progression. Our software is the first of its kind available for preclinical researchers and comes pre-packaged for applications in the following areas of research: oncology, cardiovascular, vascular, neurobiology and molecular imaging. Click here to learn more about Vevo LAB.


Vevo® LAB Software Upgrade 1.7.1 is now available. We will be posting this download to our customer website in the near future. If you'd like to download it today, contact us for the download link. 
NEW! Vevo BLOG
Recently we introduced our Vevo Blog now available on the VisualSonics website. Stay informed. Stay connected. Each week, we will share with you industry news, product information and other interesting topics. Check out our very first blog entry by clicking here.
Miss the March webinar? No problem, you can watch it here!

Presented by Dr. Carlton Bates, Professor of Pediatrics at the University of Pittsburgh.

Topics:
  • Kidney cystograms by Contrast enhanced ultrasound to detect vesicoureteral reflux in mice
  • Ultrasound of progressive bladder distension and hydronephrosis in genetic mouse models - a comparison with histology and gross dissection
  • Brief overview on the International Workshop on Developmental Nephrology
Click here to watch the presentation.

International Workshop on Nephrology Development, Registration now open.  Visit: http://iwdn.ipna-online.org/
Upcoming Events 

Live Webinar - On Demand Tutorial: How to Measure Cardiac Wall Strain Date:April 15, 2015
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AACR - American Association for Cancer Research- Booth # 2012
Dates: April 18 - 22, 2015
Pennsylvania Convention Center, Philadelphia, PA

Click here for more information.
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1st Australian Cancer and Metabolism Meeting Dates: April 29 - May 1, 2015 Sydney, Australia Click here for more information.
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