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Photoacoustic Technology

Photoacoustics is a ground-breaking, real-time imaging modality for visualizing small animal anatomy and analyzing function in vivo and non-invasively. It is the future of preclinical imaging in real-time.

Applications of Photoacoustic Imaging include:

 

           
Cancer   Neurobiology   Nanoparticle Detection & Quantification   Developmental Biology   Stroke & Diabetes (Ischemia)

Photoacoustics Features:

  • Inherent co-registration of photoacoustic signal to 2D/3D anatomical target
  • Sensitive, specific molecular data for tumor microenvironment studies
  • Real-time, in vivo imaging of deep tissue
  • Resolution down to 45 µm allows detailed anatomical analysis
  • 3D imaging with respiration gating
  • Longitudinal tumor imaging for therapeutic/drug studies
  • In vivo nanoparticle imaging
         
Transcranial mouse cerebral vasculature   Oxygen saturation map of mouse embryo showing head and heart   3D visualization of a subcutaneous 3D tumor in a mouse hindlimb at 800 nm

The Vevo® LAZR Photoacoustic Imaging System inherently co-registers structural and functional data, simultaneously collecting and displaying high-resolution micro-ultrasound and photoacoustic signals for unrivalled small animal imaging.

Anatomical, functional, physiological, and molecular data acquisition.
One system.

Applications include:

  • Quantification of oxygen saturation and hemoglobin content
  • Microvascular hemodynamics in real-time
  • Molecular and cellular imaging
  • 3D volumetric acquisition
  • Vevo Multiplexer tool to detect signal from multiple sources and co-register to
    anatomy
  • Longitudinal monitoring for therapeutic interventions in the same animal over time
  • High sensitivity, high specificity, real-time 3D imaging
  • Spectro functionality for characterization of photoacoustic signal throughout the 680 – 970 nm range
  • 3D Thresholding for optimized signal intensity during data analysis
  • Vevo Color for differentiating various anatomical targets
 
The Vevo LAZR Photoacoustic Imaging System. Explore the newest small animal imaging modality, offering 3D visualization, tumor imaging, hemoglobin quantification and oxygen saturation.