Applications - Adult Cardiology
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Human mesenchymal stromal cells improve scar thickness without enhancing cardiac function in a chronic ischaemic heart failure model
Victor Dayan1, Gustavo Yannarelli1, Paola Filomeno1 and Armand Keating1,2 Interactive Cardiovascular and Thoracic Surgery. 2012 May;14(5):516-20. Epub 2012 Feb 22 |
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Functional Impairment of Human Resident Cardiac Stem Cells by the Cardiotoxic Antineoplastic Agent Trastuzumab
Andreas S. Barth1, Yiqiang Zhang2, Taosheng Li2, Rachel R. Smith2, Isotta Chimenti2, Ioannis Terrovitis2, Darryl R. Davis2, Eddy Kizana2, Alice S. Ho3, Brian O\'Rourke1, Antonio C. Wolff4, Gary Gerstenblith1 and Eduardo Marbán2 Stem Cells Translational Medicine. 2012 Apr 12; |
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Endothelial expression of hypoxia-inducible factor 1 protects the murine heart and aorta from pressure overload by suppression of TGF-ß signaling
Hong Wei1,2, Djahida Bedja3, Norimichi Koitabashi4, Dongmei Xing5, Jasper Chen1,2, Karen Fox-Talbot6, Rosanne Rouf4, Shaoping Chen1,2, Charles Steenbergen6, John W. Harmon5, Harry C. Dietz2,7, Kathleen L. Gabrielson3, David A. Kass4, and Gregg L. Semenza1,2,4,7,8,9,10 Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2012 Apr 3;109(14):E841-50. Epub 2012 Mar 8 |
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Agonist-Independent Constitutive Activity of Angiotensin II Receptor Promotes Cardiac Remodeling in Mice
Noritaka Yasuda, Hiroshi Akazawa, Kaoru Ito, Ippei Shimizu, Yoko Kudo-Sakamoto, Chizuru Yabumoto, Masamichi Yano, Rie Yamamoto, Yukako Ozasa, Tohru Minamino, Atsuhiko T. Naito, Toru Oka, Ichiro Shiojima, Kouichi Tamura, Satoshi Umemura, Mona Nemer, Issei Komuro Hypertension. 2012 Mar;59(3):627-33. Epub 2012 Jan 30 |
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Mitochondrial oxidative stress in aortic stiffening with age: the role of smooth muscle cell function
Rui-Hai Zhou, Aleksandr E. Vendrov, Igor Tchivilev, Xi-Lin Niu, Kimberly C. Molnar, Mauricio Rojas, Jacqueline D. Carter, Haiyan Tong, George A. Stouffer, Nageswara R. Madamanchi, Marschall S. Runge Arteriosclerosis, Thrombosis, and Vascular Biology. 2012 Mar;32(3):745-55. Epub 2011 Dec 22 |
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Spontaneous Ventricular Fibrillation in Right Ventricular Failure Secondary to Chronic Pulmonary Hypertension
Soban Umar, MD, PhD, Jong-Hwan Lee, MD, PhD, Enno de Lange, PhD, Andrea Iorga, BSc, Rod Partow-Navid, BSc, Aneesh Bapat, BSc, Arnoud van der Laarse, PhD, Rajeev Saggar, MD, Rajan Saggar, MD, Dirk L. Ypey, PhD, Hrayr S. Karagueuzian, PhD, FACC and Mansoureh Eghbali, PhD Circulation: Arrhythmia and Electrophysiology 2012 Feb 1;5(1):181-90. Epub 2011 Dec 22 |
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Platelet TGF-ß1 contributions to plasma TGF-ß1, cardiac fibrosis, and systolic dysfunction in a mouse model of pressure overload
Alexander Meyer1, Wei Wang1, Jiaxiang Qu2, Lori Croft3, Jay L. Degen4, Barry S. Coller1, and Jasimuddin Ahamed1 Blood. 2012 Jan 26;119(4):1064-74. Epub 2011 Dec 1 |
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Glycogen synthase kinase-3a limits ischemic injury, cardiac rupture, post-myocardial infarction remodeling and death
Hind Lal, PhD; Jibin Zhou, MD, PhD; Firdos Ahmad, PhD; Raihana Zaka, PhD; Ronald J. Vagnozzi, BS; Morgan DeCaul, BS; James Woodgett, PhD; Erhe Gao, MD, PhD; Thomas Force, MD Circulation. 2012 Jan 3;125(1):65-75. Epub 2011 Nov 15 |
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Chronic Low-Level Arsenite Exposure through Drinking Water Increases Blood Pressure and Promotes Concentric Left Ventricular Hypertrophy in Female Mice
Pablo Sanchez-Soria1, Derrick Broka1, Sarah L. Monks1, Todd D. Camenisch1,2,3,4 Toxicologic Pathology. 2012 Jan 3. [Epub ahead of print] |
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Cardiac Hypertrophy Is Positively Regulated by MicroRNA miR-23a
Kun Wang, Zhi-Qiang Lin, Bo Long, Jian-Hui Li, Jing Zhou and Pei-Feng Li The Journal of Biological Chemistry. 2012 Jan 2;287(1):589-99. Epub 2011 Nov 14 |
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Role of uncoupled endothelial nitric oxide synthase in abdominal aortic aneurysm formation: treatment with folic Acid
Ling Gao, Kin L. Siu, Karel Chalupsky, Andrew Nguyen, Peng Chen, Neal L. Weintraub, Zorina Galis, Hua Cai Hypertension. 2012 Jan;59(1):158-66. Epub 2011 Nov 14 |
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Relationship of glucose and oleate metabolism to cardiac function in lipin-1 deficient (fld) mice
Bernard P. C. Kok1, Petra C. Kienesberger2,3, Jason R. B. Dyck2,3, and David N. Brindley1,3 Journal of Liped Research. 2012 Jan;53(1):105-18. Epub 2011 Nov 5 |
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Nerve Growth Factor Gene Therapy Using Adeno-Associated Viral Vectors Prevents Cardiomyopathy in Type 1 Diabetic Mice
Marco Meloni1, Betty Descamps1, Andrea Caporali1, Lorena Zentilin2, Ilaria Floris1, Mauro Giacca2 and Costanza Emanueli1 Diabetes. 2012 Jan;61(1):229-40 |
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Cardiac dysfunction and impaired compensatory response to pressure overload in mice deficient in stem cell antigen-1
Nathalie Rosenblatt-Velin1, Sandy Ogay1, Allison Felley2, William L. Stanford3 and Thierry Pedrazzini1 The FASEB Journal. 2012 Jan;26(1):229-39. Epub 2011 Sep 28 |
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Beneficial Effects of Long-Term Administration of an Oral Formulation of Angiotensin-(1–7) in Infarcted Rats
Fúlvia D. Marques,1,2 Marcos B. Melo,1 Leandro E. Souza,1 Maria Claúdia C. Irigoyen,1 Rúben D. Sinisterra,1,3 Frederico B. de Sousa,1 SÃlvia Q. Savergnini,1,2 VinÃcius B. A. Braga,4 Anderson J. Ferreira,1,4 and Robson A. S. Santos1,2 International Journal of Hypertension. 2012 Jan; |
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Mice With Cardiac Overexpression of Peroxisome Proliferator–Activated Receptor γ Have Impaired Repolarization and Spontaneous Fatal Ventricular Arrhythmias
John P. Morrow, MD; Alexander Katchman, PhD; Ni-Huiping Son, MD; Chad M. Trent, BS; Raffay Khan, MD; Takayuki Shiomi, MD; Haiyan Huang, MD, PhD; Vaibhav Amin, BS; Joshua M. Lader, MD; Carolina Vasquez, PhD; Gregory E. Morley, PhD; Jeanine D\'Armiento, MD, PhD; Shunichi Homma, MD; Ira J. Goldberg, MD; Steven O. Marx, MD Circulation. 2011 Dec 20;124(25):2812-21. Epub 2011 Nov 28 |
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Doxycycline reduces fibril formation in a transgenic mouse model of AL amyloidosis
Jennifer Ellis Ward1,2, Ruiyi Ren1,3, Gianluca Toraldo2, Pam SooHoo1,4, Jian Guan1,2, Carl O\'Hara1,4, Ravi Jasuja2, Vickery Trinkaus-Randall1,3, Ronglih Liao5, Lawreen H. Connors1,3, and David C. Seldin1,2 Blood. 2011 Dec 15;118(25):6610-7. Epub 2011 Oct 12 |
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Bioengineered human vascular networks transplanted into secondary mice reconnect with the host vasculature and re-establish perfusion
Kyu-Tae Kang1, Patrick Allen1,2, and Joyce Bischoff1 Blood. 2011 Dec 15;118(25):6718-21. Epub 2011 Oct 28 |
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Acute myocardial infarction activates progenitor cells and increases Wnt signalling in the bone marrow
Birgit Assmus1, Masayoshi Iwasaki2, Volker Schächinger1, Tino Roexe2, Masamichi Koyanagi2, Kazuma Iekushi2, Quanfu Xu2, Torsten Tonn3, Erhard Seifried3, Stefan Liebner4, Wolfgang Tilman Kranert5, Frank Grünwald5, Stefanie Dimmeler2 and Andreas M. Zeiher1 European Heart Journal. 2011 Dec 15. [Epub ahead of print] |
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Pathogenesis of lethal cardiac arrhythmias in mecp2 mutant mice: implication for therapy in rett syndrome
Mark D. McCauley1,2, Tiannan Wang1, Elise Mike1, Jose Herrera3, David L. Beavers1,2, Teng-Wei Huang4, Christopher S. Ward5, Steven Skinner6, Alan K. Percy7, Daniel G. Glaze8, Xander H. T. Wehrens1,2,3, and Jeffrey L. Neul1,3,4,5,9,10 Science Translational Medicine. 2011 Dec 14;3(113):113ra125 |
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Treatment with selumetinib preserves cardiac function and improves survival in cardiomyopathy caused by mutation in the lamin A/C gene
Antoine Muchir1,2, Sarah A. Reilly1,2,3, Wei Wu1,2, Shinichi Iwata1, Shunichi Homma1, Gisèle Bonne4,5,6 and Howard J. Worman1,2 Cardiovascular Research. 2011 Dec 7. [Epub ahead of print] |
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The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse
Eleonora Mezzaroma1,2,3, Stefano Toldo1,2, Daniela Farkas2, Ignacio M. Seropian1,2,3, Benjamin W. Van Tassell2,3, Fadi N. Salloum1, Harsha R. Kannan1,2, Angela C. Menna1,2, Norbert F. Voelkel1,2, and Antonio Abbate1,2 Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2011 Dec 6;108(49):19725-30. Epub 2011 Nov 21 |
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Heart failure mice exhibit decreased gastric emptying and intestinal absorption
Anteneh Addisu1,3, William R Gower Jr1,2,3,4, Maria Serrano5, Daniel Villarreal6 and John R Dietz1,3 Experimental Biology and Medicine. 2011 Dec 1;236(12):1454-60. Epub 2011 Oct 13 |
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Lipocalin-2 induces cardiomyocyte apoptosis by increasing intracellular iron accumulation
Guoxiong Xu1, JinHee Ahn1, SoYoung Chang1, Megumi Eguchi1,6, Arnaud Ogier2, SungJun Han3, YoungSam Park3, ChiYoung Shim4, YangSoo Jang4, Bo Yang5, Aimin Xu5, Yu Wang5 and Gary Sweeney1,6 The Journal of Biological Chemistry. 2011 Nov 22. [Epub ahead of print] |
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Regression of cardiac hypertrophy by granulocyte colony-stimulating factor-stimulated interleukin-1ß synthesis
Sebastian Szardien1, Holger M. Nef1,2, Sandra Voss3, Christian Troidl3, Christoph Liebetrau1,2, Jedrzej Hoffmann3, Maximilian Rauch3, Katharina Mayer3, Kathrin Kimmich3, Andreas Rolf1,2, Johannes Rixe1,2, Kerstin Troidl4, Baktybek Kojonazarov5, Ralph T. Schermuly5, Sawa Kostin4, Albrecht Elsässer6, Christian W. Hamm1,2 and Helge Möllmann1,2 European Heart Journal. 2011 Nov 21. [Epub ahead of print] |
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Oxygen cycling in conjunction with stem cell transplantation induces NOS3 expression leading to attenuation of fibrosis and improved cardiac function
Mahmood Khan1, Sarath Meduru1, Rajan Gogna1, Esha Madan1, Lucas Citro1, Muthulakshmi L. Kuppusamy1, Muzzammil Sayyid1, Mahmoud Mostafa1, Robert L. Hamlin2 and Periannan Kuppusamy1 Cardiovascular Research. 2011 Nov 21. [Epub ahead of print] |
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Dehydroepiandrosterone inhibits the Src/STAT3 constitutive activation in pulmonary arterial hypertension
Roxane Paulin1, Jolyane Meloche1, Maria Helena Jacob1, Malik Bisserier2, Audrey Courboulin1, and Sébastien Bonnet1 American Journal of Physiology. Heart and Circulatory Physiology. 2011 Nov;301(5):H1798-809. Epub 2011 Sep 2 |
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Fatty Acid Synthase Modulates Homeostatic Responses to Myocardial Stress
Babak Razani1,2, Haixia Zhang3, P. Christian Schulze5, Joel D. Schilling2, John Verbsky3, Irfan J. Lodhi1, Veli K. Topkara2, Chu Feng1, Trey Coleman1, Attila Kovacs2, Daniel P. Kelly6, Jeffrey E. Saffitz7, Gerald W. Dorn II4, Colin G. Nichols3 and Clay F. Semenkovich1,3 The Journal of Biological Chemistry. 2011 Sep 2;286(35):30949-61. Epub 2011 Jul 8 |
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Mitochondrial-targeted Signal Transducer and Activator of Transcription 3 (STAT3) Protects against Ischemia-induced Changes in the Electron Transport Chain and the Generation of Reactive Oxygen Species
Karol Szczepanek1,2,3, Qun Chen2, Marta Derecka1,4, Fadi N. Salloum2, Qifang Zhang1, Magdalena Szelag1,3, Joanna Cichy4, Rakesh C. Kukreja2, Jozef Dulak3, Edward J. Lesnefsky1,2,5 and Andrew C. Larner1,2 The Journal of Biological Chemistry. 2011 Aug 26;286(34):29610-20. Epub 2011 Jun 29 |
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A critical role for macrophages in neovessel formation and the development of stenosis in tissue-engineered vascular grafts
Narutoshi Hibino, Tai Yi, Daniel R. Duncan, Animesh Rathore, Ethan Dean, Yuji Naito, Alan Dardik, Themis Kyriakides, Joseph Madri, Jordan S. Pober, Toshiharu Shinoka and Christopher K. Breuer The Journal of the Federation of American Societies for Experimental Biology (FASEB). 2011 Aug 24. [Epub ahead of print] |
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Granulocyte colony-stimulating factor treatment plus dipeptidylpeptidase-IV inhibition augments myocardial regeneration in mice expressing cyclin D2 in adult cardiomyocytes
Marc-Michael Zaruba1,2, Wuqiang Zhu2, Mark H. Soonpaa2,3, Sean Reuter2, Wolfgang-Michael Franz1 and Loren J. Field2,3 European Heart Journal. 2011 Aug 17. [Epub ahead of print] |
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Dimethylarginine Dimethylaminohydrolase-1 Is the Critical Enzyme for Degrading the Cardiovascular Risk Factor Asymmetrical Dimethylarginine
Xinli Hu, Dorothee Atzler, Xin Xu, Ping Zhang, Haipeng Guo, Zhongbing Lu, John Fassett, Edzard Schwedhelm, Rainer H. Böger, Robert J. Bache, Yingjie Chen Arteriosclerosis, Thrombosis and Vascular Biology. 2011 Jul;31(7):1540-6. Epub 2011 Apr 14 |
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IQGAP1 regulates ERK1/2 and AKT signalling in the heart and sustains functional remodelling upon pressure overload
Mauro Sbroggiò1, Daniela Carnevale2, Alessandro Bertero1, Giuseppe Cifelli2, Emanuele De Blasio1, Giada Mascio2, Emilio Hirsch1, Wadie F. Bahou3, Emilia Turco1, Lorenzo Silengo1, Mara Brancaccio1, Giuseppe Lembo2,4 and Guido Tarone1 Cardiovascular Research. 2011 Jun 17. [Epub ahead of print] |
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Mitofusin 2 Inhibits Angiotensin II-Induced Myocardial Hypertrophy
Haiyi Yu, MD, Yanhong Guo, MD, PhD, Lin Mi, Xueying Wang, MD, Lei Li, MD, and Wei Gao, MD Journal of Cardiovascular Pharmacology and Therapeutics. 2011 Jun;16(2):205-11. Epub 2010 Nov 24 |
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Disrupting the EMMPRIN (CD147)–Cyclophilin A Interaction Reduces Infarct Size and Preserves Systolic Function After Myocardial Ischemia and Reperfusion
Peter Seizer; Carmen Ochmann; Tanja Schönberger; Sebastian Zach; Melanie Rose; Oliver Borst; Karin Klingel; Reinhard Kandolf; H. Robson MacDonald; Romana A. Nowak; Stefan Engelhardt; Florian Lang; Meinrad Gawaz; Andreas E. May Arteriosclerosis, Thrombosis and Vascular Biology. 2011 Jun;31(6):1377-86. Epub 2011 Mar 24 |
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Mitigation of the progression of heart failure with sildenafil involves inhibition of RhoA/Rho-kinase pathway
Vinh Q. Chau, Fadi N. Salloum, Nicholas N. Hoke, Antonio Abbate, and Rakesh C. Kukreja American Journal of Physiology. Heart and Circulatory Physiology. 2011 Jun;300(6):H2272-9. Epub 2011 Mar 11 |
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Effects of a synthetic PEG-ylated Tie-2 agonist peptide on endotoxemic lung injury and mortality
Sascha David1, Chandra C. Ghosh1, Philipp Kümpers2, Nelli Shushakova3, Paul Van Slyke4, Eliyahu V. Khankin5, S. Ananth Karumanchi5, Dan Dumont4, and Samir M. Parikh1 American journal of physiology. Lung cellular and molecular physiology. 2011 Jun;300(6):L851-62. Epub 2011 Mar 18 |
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Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules
Naohiro Yamaguchi1, Asima Chakraborty1, Daniel A. Pasek1, Jeffery D. Molkentin2, and Gerhard Meissner1 American Journal of Physiology. Heart and Circulatory Physiology. 2011 Jun;300(6):H2187-95. Epub 2011 Mar 18 |
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Therapeutic efficacy of TBC3711 in monocrotaline-induced pulmonary hypertension
Djuro Kosanovic1, Baktybek Kojonazarov1, Himal Luitel1, Bhola K Dahal1, Akylbek Sydykov1, Teodora Cornitescu1, Wiebke Janssen2, Ralf P Brandes3, Neil Davie4, Hossein A Ghofrani1, Norbert Weissmann1, Friedrich Grimminger1, Werner Seeger1,2 and Ralph T Schermuly1,2 Respiratory Research. 2011 Jun 23;12:87 |
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Calcific Aortic Valve Stenosis: Methods, Models, and Mechanisms
Jordan D. Miller, Robert M. Weiss, Donald D. Heistad Circulation Research. 2011 May 27;108(11):1392-412 |
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Endothelium-Derived Neuregulin Protects the Heart Against Ischemic Injury
Nadia Hedhli, PhD; Qunhua Huang, PhD; April Kalinowski, MS; Monica Palmeri, MS; Xiaoyue Hu, MD; Raymond R. Russell, MD, PhD; Kerry S. Russell, MD, PhD Circulation. 2011 May 24;123(20):2254-62. Epub 2011 May 9 |
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Intravenous Gene Therapy With PIM-1 Via a Cardiotropic Viral Vector Halts the Progression of Diabetic Cardiomyopathy Through Promotion of Prosurvival Signaling
Rajesh Katare, Andrea Caporali, Lorena Zentilin, Elisa Avolio, Graciela Sala-Newby, Atsuhiko Oikawa, Daniela Cesselli, Antonio Paolo Beltrami, Mauro Giacca, Costanza Emanueli, Paolo Madeddu Circulation Research. 2011 May 13;108(10):1238-51. Epub 2011 Apr 7 |
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p53 Gene deficiency promotes hypoxia-induced pulmonary hypertension and vascular remodeling in mice
Shiro Mizuno1,2, Herman J. Bogaard2, Donatas Kraskauskas2, Aysar Alhussaini2, Jose Gomez-Arroyo2, Norbert F. Voelkel2, and Takeshi Ishizaki3 American journal of physiology. Lung cellular and molecular physiology. 2011 May;300(5):L753-61. Epub 2011 Feb 18 |
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Angiotensin type I receptor blockade in conjunction with enhanced Akt activation restores coronary collateral growth in the metabolic syndrome
Rashmi Jadhav1, Tracy Dodd1, Erika Smith1, Erin Bailey2, Angelo L. DeLucia2, James C. Russell3, Rowan Madison4, Barry Potter4, Kenneth Walsh5, Hanjoong Jo6, and Petra Rocic1 American Journal of Physiology. Heart and Circulatory Physiology. 2011 May;300(5):H1938-49. Epub 2011 Feb 18 |
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Mammalian enabled (Mena) is a critical regulator of cardiac function
Frédérick Aguilar1, Stephen L. Belmonte1, Rashmi Ram1, Sami F. Noujaim2, Olga Dunaevsky1, Tricia L. Protack1, Jose Jalife2, H. Todd Massey3, Frank B. Gertler4, and Burns C. Blaxall1 American Journal of Physiology. Heart and Circulatory Physiology. 2011 May;300(5):H1841-52. Epub 2011 Feb 18 |
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Vascular rhexis in mice subjected to non-sustained myocardial ischemia and its therapeutic implications
A K M Tarikuz Zaman1, Christopher J French1, Jeffrey L Spees1, Azan S Binbrek2 and Burton E Sobel1 Experimental Biology and Medicine. 2011 May 1;236(5):598-603. Epub 2011 Apr 26 |
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Dietary Nitrate Supplementation Protects Against Doxorubicin-Induced Cardiomyopathy by Improving Mitochondrial Function
Shu-Guang Zhu, MD, PhD1, Rakesh C. Kukreja, PhD1, Anindita Das, PhD1, Qun Chen, MD, PhD1, Edward J. Lesnefsky, MD1,2, and Lei Xi, MD1 Journal of the American College of Cardiology. 2011 May; 57 (21), pg. 2181-2189 |
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c-Jun N-terminal Kinase (JNK-1) Confers Protection against Brief but Not Extended Ischemia during Acute Myocardial Infarction
Jianqin Wei, Weiwen Wang, Ines Chopra, Hui Fang Li, Christopher J. Dougherty, Jennipher Adi, Nikhil Adi, Huilan Wang and Keith A. Webster The Journal of Biological Chemistry. 2011 Apr 22;286(16):13995-4006. Epub 2011 Feb 15. |
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Echocardiographic Speckle-Tracking–Based Strain Imaging for Rapid Cardiovascular Phenotyping in Mice
Michael Bauer, Susan Cheng, Mohit Jain, Soeun Ngoy, Catherine Theodoropoulos, Anna Trujillo, Fen-Chiung Lin Ronglih Liao Circulation Research. 2011 Apr 15;108(8):908-16. Epub 2011 Mar 3. |
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A Central Role for CD68(+) Macrophages in Hepatopulmonary Syndrome: Reversal by Macrophage Depletion
Thenappan Thenappan1, Ankush Goel1, Glenn Marsboom1, Yong-Hu Fang1, Peter T Toth1, Hannah J Zhang1, Hidemi Kajimoto2, Zhigang Hong1, Jonathan Paul1, Christian Wietholt1, Jennifer Pogoriler1, Lin Piao1, Jalees Rehman1, and Stephen L Archer1 American Journal of Respiratory and Creitical Care Medicine. 2011 Apr 15;183(8):1080-91. Epub 2010 Dec 10 |
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DGAT1 deficiency decreases PPAR expression and does not lead to lipotoxicity in cardiac and skeletal muscle
Li Liu1, Shuiqing Yu1, Raffay S. Khan1, Gene P. Ables1, Kalyani G. Bharadwaj1, Yunying Hu1, Lesley A. Huggins1, Jan W. Eriksson2,3, Linda K. Buckett4, Andrew V. Turnbull4, Henry N. Ginsberg1, William S. Blaner1, Li-Shin Huang1 and Ira J. Goldberg1 Journal of Lipid Research. 2011 Apr;52(4):732-44. Epub 2011 Jan 3. |
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Caveolin-1 deficiency exacerbates cardiac dysfunction and reduces survival in mice with myocardial infarction
Jean-François Jasmin1,2, Giuseppe Rengo3,4, Anastasios Lymperopoulos3,5, Ratika Gupta1, Gregory J. Eaton1, Kevin Quann1, Donna M. Gonzales1, Isabelle Mercier1,2, Walter J. Koch3, and Michael P. Lisanti1,2,6,7 Heart and Circulatory Physiology. 2011 Apr;300(4):H1274-81. Epub 2011 Feb 4. |
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CC chemokine receptor 5 deletion impairs macrophage activation and induces adverse remodeling following myocardial infarction
Rogelio Zamilpa1, Rushit Kanakia2, Joaquin Cigarroa IV2, Qiuxia Dai1, G. Patricia Escobar2, Hernan Martinez3, Fabio Jimenez3, Seema S. Ahuja3, and Merry L. Lindsey1 Heart and Circulatory Physiology. 2011 Apr;300(4):H1418-26. Epub 2011 Feb 4. |
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Impaired Phosphatidylcholine Biosynthesis Reduces Atherosclerosis and Prevents Lipotoxic Cardiac Dysfunction in ApoE–/– Mice
Laura K. Cole, Vernon W. Dolinsky, Jason R.B. Dyck, Dennis E. Vance Circulation Research. 2011 Mar 18;108(6):686-94. Epub 2011 Jan 27. |
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Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice
Shende P, Plaisance I, Morandi C, Pellieux C, Berthonneche C, Zorzato F, Krishnan J, Lerch R, Hall MN, Rüegg MA, Pedrazzini T, Brink M. Circulation. 2011 Mar 15;123(10):1073-82. Epub 2011 Feb 28. |
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Eph-B4 prevents venous adaptive remodeling in the adult arterial environment
Akihito Muto1,2, Tai Yi2, Kenneth D. Harrison2, Alberto Dávalos2, Tiffany T. Fancher3, Kenneth R. Ziegler1,2, Amanda Feigel1,2, Yuka Kondo1,2, Toshiya Nishibe4, William C. Sessa2, and Alan Dardik1,2,5 The Journal of General Physiology. 2011 Mar 14;208(3):561-75. Epub 2011 Feb 21. |
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miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes
Li Qian1,2,3, Linda W. Van Laake1,2,3,5, Yu Huang1,2,3, Siyuan Liu4, Michael F. Wendland4, and Deepak Srivastava1 The Journal of Experiemental Medicine. 2011 Mar 14;208(3):549-60. Epub 2011 Mar 7. |
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Disrupted Junctional Membrane Complexes and Hyperactive Ryanodine Receptors After Acute Junctophilin Knockdown in Mice
Ralph J. van Oort, PhD; Alejandro Garbino, PhD; Wei Wang, PhD; Sayali S. Dixit, PhD; Andrew P. Landstrom, BS; Namit Gaur, MS; Angela C. De Almeida, MS; Darlene G. Skapura, BS; Yoram Rudy, PhD; Alan R. Burns, PhD; Michael J. Ackerman, MD, PhD; Xander H.T. Wehrens, MD, PhD Circulation. 2011 Mar 8;123(9):979-88. Epub 2011 Feb 21. |
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Mitofusin-2 Maintains Mitochondrial Structure And Contributes To Stress-Induced Permeability Transition in Cardiac Myocytes
Kyriakos N. Papanicolaou, Ramzi J. Khairallah, Gladys Ngoh, Aristide Chikando, Ivan Luptak, Karen O\'Shea, Dushon D. Riley, Jesse J. Lugus, Wilson S. Colucci, W. Jonathan Lederer, William C. Stanley, and Kenneth Walsh Molecular and Cellular Biology. 2011 Mar;31(6):1309-28. Epub 2011 Jan 18 |
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An Oral Formulation of Angiotensin-(1-7) Produces Cardioprotective Effects in Infarcted and Isoproterenol-Treated Rats
Fúlvia D. Marques; Anderson J. Ferreira; Rubén D.M. Sinisterra; Bruno A. Jacoby; Frederico B. Sousa; Marcelo V. Caliari; Gerluza A.B. Silva; Marcos B. Melo; Ana P. Nadu; Leandro E. Souza; Maria C.C. Irigoyen; Alvair P. Almeida; Robson A.S. Santos Hypertension. 2011 Mar;57(3):477-83. Epub 2011 Jan 31. |
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Notch1 in Bone Marrow–Derived Cells Mediates Cardiac Repair After Myocardial Infarction
Yuxin Li, MD, PhD; Yukio Hiroi, MD, PhD; Soeun Ngoy, BS; Ryuji Okamoto, MD, PhD; Kensuke Noma, MD, PhD; Chao-Yung Wang, MD; Hong-Wei Wang, MD, PhD; Qian Zhou, MD; Freddy Radtke, PhD; Ronglih Liao, PhD; James K. Liao, MD Circulation Molecular Cardiology. 2011 Mar 1;123(8):866-76. Epub 2011 Feb 14. |
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Estrogen Receptor-ß Signals Left Ventricular Hypertrophy Sex Differences in Normotensive Deoxycorticosterone Acetate-Salt Mice
Dennis Gürgen; Björn Hegner; Angelika Kusch; Rusan Catar; Lyubov Chaykovska; Uwe Hoff; Volkmar Gross; Torsten Slowinski; Andrey C. da Costa Goncalves; Ulrich Kintscher; Jan-Åke Gustafsson; Friedrich C. Luft; Duska Dragun Hypertension. 2011 Mar;57(3):648-54. Epub 2011 Feb 7. |
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Losartan Decreases Cardiac Muscle Fibrosis and Improves Cardiac Function in Dystrophin-Deficient Mdx Mice
Christopher F. Spurney, MD, Arpana Sali, MS, Alfredo D. Guerron, MD, Micaela Iantorno, MD, Qing Yu, MD, PhD, Heather Gordish-Dressman, PhD, Sree Rayavarapu, DVM, Jack van der Meulen, PhD, Eric P. Hoffman, PhD, Kanneboyina Nagaraju, DVM, PhD Journal of Cardiovascular Pharmacology and Therapeutics. 2011 Mar;16(1):87-95. |
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Hepatocyte growth factor mobilizes non-bone marrow-derived circulating mesoangioblasts
Masayoshi Iwasaki1, Masamichi Koyanagi1, Hans Kossmann1, Nadejda Monsefi2, Stefan Rupp1,3, Janina Trauth1,3, Patrick Paulus4, Rebekka Goetz1,3, Stefan Momma5, Marc Tjwa1, Kisho Ohtani1, Reinhard Henschler6, Dietmar Schranz3, Giulio Cossu7, Kai Zacharowski4, Sven Martens2, Andreas M. Zeiher8 and Stefanie Dimmeler1 European Heart Journal. 2011 Mar;32(5):627-36. Epub 2010 Dec 29 |
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Enhanced expression of DYRK1A in cardiomyocytes inhibits acute NFAT activation but does not prevent hypertrophy in vivo
Cornelia Grebe1, Theda-Maria Klingebiel1, Simon Philipp Grau1, Karl Toischer1, Michael Didié2, Claudius Jacobshagen1, Christian Dullin3, Gerd Hasenfuss1 and Tim Seidler1 Cardiovascular Research. 2011 Feb 20. [Epub ahead of print] |
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Sustained Hemodynamic Stress Disrupts Normal Circadian Rhythms in Calcineurin-Dependent Signaling and Protein Phosphorylation in the Heart
Nita Sachan, Asim Dey, David Rotter, D. Bennett Grinsfelder, Pavan K. Battiprolu, Devanjan Sikder, Victoria Copeland, Misook Oh, Erik Bush, John M. Shelton, James A. Bibb, Joseph A. Hill, Beverly A. Rothermel Circulation Research. 2011 Feb 18;108(4):437-45. Epub 2011 Jan 13. |
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Non- invasive in vivo analysis of a murine aortic graft using high resolution ultrasound microimaging
Rowinska Z, Zander S, Zernecke A, Jacobs M, Langer S, Weber C, Merx MW, Koeppel TA European Journal of Radiology. 2011 Feb 17. [Epub ahead of print] |
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Electrical remodelling precedes heart failure in an endothelin-1-induced model of cardiomyopathy
Erin E. Mueller1, Abdul Momen2, Stéphane Massé2, Yu-Qing Zhou3, Jie Liu4, Peter H. Backx4,5, R. Mark Henkelman3,6, Kumaraswamy Nanthakumar2,7, Duncan J. Stewart1,7,8 and Mansoor Husain1,2,4,5,7 Cardiovascular Research. 2011 Feb 15;89(3):623-33. Epub 2010 Nov 9 |
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Load-Reducing Therapy Prevents Development of Arrhythmogenic Right Ventricular Cardiomyopathy in Plakoglobin-Deficient Mice
Larissa Fabritz, MD1, Mark G. Hoogendijk, MD2, Brendon P. Scicluna, MSc2, Shirley C.M. van Amersfoorth, MSc2, Lisa Fortmueller, DVM1, Susanne Wolf, DVM1, Sandra Laakmann, DVM1, Nina Kreienkamp1, Ilaria Piccini, PhD1, Günter Breithardt, MD1, Patricia Ruiz Noppinger, PhD3, Henning Witt, PhD3, Klaus Ebnet, PhD4, Thomas Wichter, MD4, Bodo Levkau, MD6, Werner W. Franke, PhD7, Sebastian Pieperhoff, PhD7, Jacques M.T. de Bakker, PhD2,8, Ruben Coronel, MD, PhD2 and Paulus Kirchhof, MD1 Journal of the American College of Cardiology. 2011 Feb 8;57(6):740-50. |
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Suppression of Histone Deacetylases Worsens Right Ventricular Dysfunction after Pulmonary Artery Banding in Rats
Harm J Bogaard1, Shiro Mizuno2, Ayser A Al Hussaini2, Stefano Toldo3, Antonio Abbate3, Donatas Kraskauskas2, Michael Kasper4, Ramesh Natarajan2, and Norbert F Voelkel2 Respiratory and Critical Care Medicine. 2011 Feb 4. [Epub ahead of print] |
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Distinct Effects of Leukocyte and Cardiac Phosphoinositide 3-Kinase Activity in Pressure Overload–Induced Cardiac Failure
Federico Damilano, PhD*; Irene Franco, BSc*; Cinzia Perrino, MD,, PhD; Katrin Schaefer, MD; Ornella Azzolino, BSc; Daniela Carnevale, PhD; Giuseppe Cifelli, BSc; Pierluigi Carullo, BSc; Riccardo Ragona, PhD; Alessandra Ghigo, BSc; Alessia Perino, BSc; Giuseppe Lembo, MD, PhD; Emilio Hirsch, PhD Circulation Heart Failure. 2011 Feb 1;123(4):391-9. Epub 2011 Jan 17. |
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Glycogen-branching enzyme deficiency leads to abnormal cardiac development: novel insights into glycogen storage disease IV
Yi-Ching Lee1,2, Chia-Jung Chang1, Deeksha Bali3, Yuan-Tsong Chen1,4 and Yu-Ting Yan1 Oxford Journals. Human Molecular Genetice. 2011 Feb 1;20(3):455-65. Epub 2010 Nov 12. |
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Temporal Effects of Catalase Overexpression on Healing After Myocardial Infarction
Karl D. Pendergrass, PhD, Susan T. Varghese, MD, MBA, Kathryn Maiellaro-Rafferty, PhD, Milton E. Brown, BS, W. Robert Taylor, MD, PhD and Michael E. Davis, PhD Circulation: Heart Failure. 2011 Jan 1;4(1):98-106. Epub 2010 Oct 22 |
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A comparison of retrospectively self-gated magnetic resonance imaging and high-frequency echocardiography for characterization of left ventricular function in mice
Brage Høyem Amundsen 1,2,3, Madelene Ericsson 1, John Georg Seland 1,4, Tina Pavlin 1, Øyvind Ellingsen 1,2 and Christian Brekken 1 Laboratory Animals. 2011 Jan;45(1):31-7. Epub 2010 Nov 3 |
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Ginseng inhibits cardiomyocyte hypertrophy and heart failure via NHE-1 inhibition and attenuation of calcineurin activation
Juan Guo, PhD, Xiaohong Tracey Gan, MSc, James V Haist, BSc, Venkatesh Rajapurohitam, PhD, Asad Zeidan, PhD, Nazo Said Faruq and Morris Karmazyn, PhD Circulation: Heart Failure. 2011 Jan 1;4(1):79-88. Epub 2010 Oct 22 |
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Removal of the calpain 3 protease reverses the myopathology in a mouse model for titinopathies
Karine Charton1, Nathalie Danièle1, Anna Vihola2, Carinne Roudaut1, Evelyne Gicquel1, François Monjaret1, Anne Tarrade3, Jaakko Sarparanta2, Bjarne Udd2,4,5 and Isabelle Richard1 Human Molecular Genetics. 2010 Dec 1;19(23):4608-24. Epub 2010 Sep 20 |
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Cardiac-specific overexpression of dominant-negative CREB leads to increased mortality and mitochondrial dysfunction in female mice
Peter A. Watson1,2, Nicholas Birdsey1,2, Gordon S. Huggins3, Eric Svensson4, Daniel Heppe1, and Leslie Knaub1,2 American Journal of Physiology. Heart and Cirulatory Physiology. 2010 Dec;299(6):H2056-68. Epub 2010 Oct 8. |
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Exercise training before cardiac-specific Serca2 disruption attenuates the decline in cardiac function in mice
Madelene Ericsson1, Cecilie Sjåland2,3, Kristin B. Andersson2,3, Ivar Sjaastad2,3, Geir Christensen2,3, Ole M. Sejersted2,3, and Øyvind Ellingsen1,4 American Phsiological Society. Journal of Applied Physiology. 2010 Dec;109(6):1749-55. Epub 2010 Sep 23. |
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The Na+/Ca2+ exchanger-1 mediates left ventricular dysfunction in mice with chronic intermittent hypoxia
Ling Chen1,2, Jin Zhang2, Xuejiao Hu3, Kenneth D. Philipson4, and Steven M. Scharf1 American Phsiological Society. Journal of Applied Physiology. 2010 Dec;109(6):1675-85. Epub 2010 Oct 14. |
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Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability
Andreas Blana1, MD, Sven Kaese1, BS, Lisa Fortmüller2,4, VetD, Sandra Laakmann2,4, VetD, Dierk Damke1, MD, Kelly van Bragt3, BS, Jens Eckstein3, MD, Ilaria Piccini1, PhD, Uwe Kirchhefer4,6, MD, Stanley Nattel5, MD, FHRS, Günter Breithardt1, MD, FHRS, Peter Carmeliet7, MD, Edward Carmeliet7, PhD, Ulrich Schotten3, MD, PhD, Sander Verheule3, PhD, Paulus Kirchhof1,4, MD, FHRS, Larissa Fabritz1,4, MD HeartRhythm. 2010 Dec;7(12):1862-9. Epub 2010 Aug 19 |
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A ZASP Missense Mutation, S196L, Leads to Cytoskeletal and Electrical Abnormalities in a Mouse Model of Cardiomyopathy
Zhaohui Li, MD, PhD, Tomohiko Ai, MD, PhD, Kaveh Samani, MD, Yutao Xi, PhD, Huei-Ping Tzeng, PhD, Mingxing Xie, MD, Shan Wu, MD, Shuping Ge, MD, Michael D. Taylor, MD, PhD, Jian-Wen Dong, MD, PhD, Jie Cheng, MD, PhD, Michael J. Ackerman, MD, PhD, Akinori Kimura, MD, Gianfranco Sinagra, MD, Luca Brunelli, MD, PhD, Georgine Faulkner, PhD and Matteo Vatta, PhD Circulation: Arrhythmia and Electrophysiology. 2010 Dec 1;3(6):646-56. Epub 2010 Sep 18 |
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Ryanodine Receptor Phosphorylation by Calcium/Calmodulin-Dependent Protein Kinase II Promotes Life-Threatening Ventricular Arrhythmias in Mice With Heart Failure
Ralph J. van Oort, PhD; Mark D. McCauley, MD; Sayali S. Dixit, PhD; Laetitia Pereira, PhD; Yi Yang, MD; Jonathan L. Respress, BS; Qiongling Wang, PhD; Angela C. De Almeida, MS; Darlene G. Skapura, BS; Mark E. Anderson, MD, PhD; Donald M. Bers, PhD; Xander H.T. Wehrens, MD, PhD Circulation. 2010 Dec 21;122(25):2669-79. Epub 2010 Nov 15. |
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A Critical Function of Th17 Proinflammatory Cells in the Development of Atherosclerotic Plaque in Mice
Qi Gao1, Yang Jiang1, Tian Ma1, Faliang Zhu1, Fei Gao2, Pin Zhang3, Chun Guo1, Qun Wang1, Xiaoyan Wang1, Chunhong Ma1, Yun Zhang2, Wanjun Chen3 and Lining Zhang1 The Journal of Immunology. 2010 Nov 15;185(10):5820-7. Epub 2010 Oct 15 |
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Nox2 NADPH Oxidase Promotes Pathologic Cardiac Remodeling Associated with Doxorubicin Chemotherapy
Youyou Zhao1, Declan McLaughlin1, Emma Robinson1, Adam P. Harvey1, Michelle B. Hookham1, Ajay M. Shah2, Barbara J. McDermott1, and David J. Grieve1 Cancer Research. 2010 Nov 15;70(22):9287-97. Epub 2010 Sep 30. |
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Sildenafil reverses cardiac dysfunction in the mdx mouse model of Duchenne muscular dystrophy
Candace M. Adamo1, Dao-Fu Dai2, Justin M. Percival3, Elina Minami4, Monte S. Willis5, Enrico Patrucco1, Stanley C. Froehner3, and Joseph A. Beavo1 Proceedings of the National Academy of Sciences of the United States of America. 2010 Nov 2;107(44):19079-83. Epub 2010 Oct 18 |
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Cre-loxP DNA recombination is possible with only minimal unspecific transcriptional changes and without cardiomyopathy in Tg(αMHC-MerCreMer) mice
Karina Hougen1,2, Jan Magnus Aronsen1,2, Mathis K. Stokke1,2, Ulla Enger1,2, Stle Nygrd1,2,3, Kristin B. Andersson1,2, Geir Christensen1,2, Ole M. Sejersted1,2, and Ivar Sjaastad1,2,4 American Journal of Physiology. Heart and Circulatory Physiology. 2010 Nov;299(5):H1671-8. Epub 2010 Aug 27 |
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Posterior lymph heart function in two species of anurans: analysis based on both in vivo pressure–volume relationships by conductance manometry and ultrasound
Dane A. Crossley, II and Stanley S. Hillman The Journal of Experimental Biology. 2010 Nov 1;213(Pt 21):3710-6 |
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Molecular Imaging of Vasa Vasorum Neovascularization via DEspR-targeted Contrast-enhanced Ultrasound Micro-imaging in Transgenic Atherosclerosis Rat Model
Julius L. Decano, Anne Marie Moran, Nelson Ruiz-Opazo, Victoria L. M. Herrera Molecular Imaging and Biology. 2010 Oct 23. [Epub ahead of print] |
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Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction
Anindita Das1, David Durrant1, Clint Mitchell2, Eric Mayton1, Nicholas N. Hoke1, Fadi N. Salloum1, Margaret A. Park2, Ian Qureshi1, Ray Lee2, Paul Dent2, and Rakesh C. Kukreja1 Proceedings of the National Academy of Sciences of the United States of America. 2010 Oct 19;107(42):18202-7. Epub 2010 Sep 30 |
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Early heart failure in the SMNΔ7 model of spinal muscular atrophy and correction by postnatal scAAV9-SMN delivery
Adam K. Bevan1,3, Kirk R. Hutchinson2,5, Kevin D. Foust1, Lyndsey Braun1, Vicki L. McGovern4, Leah Schmelzer1, Jennifer G. Ward6, Jeffrey C. Petruska7,8, Pamela A. Lucchesi2, Arthur H.M. Burghes3,4 and Brian K. Kaspar1,3,4 Human Molecular Genetics. 2010 Oct 15;19(20):3895-905. Epub 2010 Jul 16 |
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Arrhythmia and cardiac defects are a feature of spinal muscular atrophy model mice
Christopher R. Heier1,2, Rosalba Satta1,2, Cathleen Lutz3 and Christine J. DiDonato1,2 Human Molecular Genetics. 2010 Oct 15;19(20):3906-18. Epub 2010 Aug 6 |
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Intracellular or extracellular heat shock protein 70 differentially regulates cardiac remodelling in pressure overload mice
Wen-Feng Cai, Xiao-Wei Zhang, Hui-Min Yan, Yong-Gang Ma, Xiao-Xing Wang, Jun Yan, Bing-Mu Xin, Xiao-Xi Lv, Qing-Qing Wang, Zi-Yan Wang, Hong-Zhen Yang and Zhuo-Wei Hu Cardiovascular Research. 2010 Oct 1;88(1):140-9. Epub 2010 Jun 10 |
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The Effects of Acarbose Treatment on Intimal Hyperplasia in a Rat Carotid Endarterectomy Model of Diet-Induced Insulin Resistance
John O. Nyalala, PhD1, Shaoke Luo, MD1, Danielle N. Campbell, MD1, Aliza T. Brown, PhD2, Mohammed M. Moursi, MD3 Vascular and Endovascular Surgery. 2010 Oct;44(7):560-567. Epub 2010 Jul 30 |
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Early activation of matrix metalloproteinases underlies the exacerbated systolic and diastolic dysfunction in mice lacking TIMP3 following myocardial infarction
Vijay Kandalam,1,4, Ratnadeep Basu,1,4, Thomas Abraham,5 Xiuhua Wang,1,4 Ahmed Awad,1,4 Wei Wang,3,4 Gary D. Lopaschuk,3,4 Nobuyo Maeda,6 Gavin Y. Oudit,2,4 and Zamaneh Kassiri1,4 American Journal of Physiology. Heart and Circulatory Physiology. 2010 Oct;299(4):H1012-23. Epub 2010 Jul 30 |
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Ventricular Dilation Is Associated With Improved Cardiovascular Performance and Survival in Sepsis
Sergio L. Zanotti Cavazzoni, MD, Massimiliano Guglielmi, MD, Joseph E. Parrillo, MD, FCCP, Tracy Walker, MD, R. Phillip Dellinger, MD and Steven M. Hollenberg, MD, FCCP Chest. 2010 Oct; vol.138 no.4, 848-855 |
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Curcumin prevents cardiac remodeling secondary to chronic renal failure through deactivation of hypertrophic signaling in rats
Siddhartha S. Ghosh, Fadi N. Salloum, Antonio Abbate, Richard Krieg, Domenic A. Sica, Todd W. Gehr, and Rakesh C. Kukreja American Journal of Physiology. Heart and Circulatory Physiology. 2010 Oct;299(4):H975-84. Epub 2010 Jul 2 |
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Cardiac Restricted Overexpression of Membrane Type-1 Matrix Metalloproteinase Causes Adverse Myocardial Remodeling following Myocardial Infarction
Francis G. Spinale1,2, Rupak Mukherjee1, Juozas A. Zavadzkas1, Christine N. Koval1, Shenikqua Bouges1, Robert E. Stroud1, Lawrence W. Dobrucki3 and Albert J. Sinusas3 The Journal of Biological Chemistry. 2010 Sep 24;285(39):30316-27. Epub 2010 Jul 19 |
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Lack of EP4 receptors on bone marrow-derived cells enhances inflammation in atherosclerotic lesions
Eva H.C. Tang1,2, Koichi Shimizu1, Thomas Christen1, Viviane Z. Rocha1, Eugenia Shvartz1, Yevgenia Tesmenitsky1, Galina Sukhova1, Guo-Ping Shi1 and Peter Libby1 Cardiovascular Research. 2010 Sep 21. [Epub ahead of print] |
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Attenuation of cardiac dysfunction by HSPA12B in endotoxin-induced sepsis in mice through a PI3K-dependent mechanism
Hongmei Zhou1, Jin Qian1, Chuanfu Li2, Jingjin Li3, Xiaojin Zhang1, Zhengnian Ding3, Xiang Gao4, Zhihua Han5, Yunlin Cheng1, and Li Liu1 Cardiovascular Research. 2010 Sep 16. [Epub ahead of print] |
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Matrix Metalloproteinases 2 and 9 Dysfunction Underlie Vascular Stiffness in Circadian Clock–Mutant Mice
Ciprian B. Anea ; M. Irfan Ali ; Jessica M. Osmond ; Jennifer C. Sullivan ; David W. Stepp ; Ana M. Merloiu ; and R. Daniel Rudic Arteriosclerosis, Thrombosis, and Vascular Biology. 2010 Sep 9. [Epub ahead of print] |
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Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy
Javid Moslehi MD, Yoji Andrew Minamishima MD, PhD, Jianru Shi PhD, Donna Neuberg DSc, David M. Charytan MD, Robert F. Padera MD, PhD, Sabina Signoretti MD, Ronglih Liao PhD, and William G. Kaelin Jr MD Circulation. 2010 Sep 7;122(10):1004-16. Epub 2010 Aug 23 |
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The critical roles of platelet activation and reduced NO bioavailability in fatal pulmonary arterial hypertension in a murine hemolysis model
Weiguo Hu1,2, Richard Jin1, Jinyan Zhang2,3, Tao You2,4, Zhihai Peng3, Xiaowen Ge2, Roderick T. Bronson5, Jose A. Halperin1,2, Joseph Loscalzo1, and Xuebin Qin1,2 Blood. 2010 Sep 2;116(9):1613-22. Epub 2010 May 28 |
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Validation of High-Resolution Echocardiography and Magnetic Resonance Imaging Versus High-Fidelity Catheterization in Experimental Pulmonary Hypertension
Dalia Urboniene,1 Idith Haber,1 Yong-Hu Fang,1 Thenappan Thenappan,1 and Stephen L. Archer1 American journal of physiology. Lung cellular and molecular physiology. 2010 Sep;299(3):L401-12. Epub 2010 Jun 25 |
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Ultrasound dynamic micro-elastography applied to the viscoelastic characterization of soft tissues and arterial walls
Cédric Schmitt1,2, Anis Hadj Henni1 and Guy Cloutier1,2,3 Ultrasound in Medicine & Biology. 2010 Sep;36(9):1492-503 |
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Expansion of human cardiac stem cells in physiological oxygen improves cell production efficiency and potency for myocardial repair
Tao-Sheng Li, Ke Cheng, Konstantinos Malliaras, Noriko Matsushita, Baiming Sun, Linda Marbán, Yiqiang Zhang and Eduardo Marbán Cardiovascular Research. 2010 Aug 21. [Epub ahead of print] |
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Novel role of C terminus of Hsc70-interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction via regulating ERK5-mediated degradation of inducible cAMP early repressor
Chang-Hoon Woo, Nhat-Tu Le, Tetsuro Shishido, Eugene Chang, Hakjoo Lee, Kyung-Sun Heo, Deanne M. Mickelsen, Yan Lu, Carolyn McClain, Thomas Spangenberg, Chen Yan, Carlos A. Molina, Jay Yang, Cam Patterson, and Jun-ichi Abe The FASEB Journal. 2010 Aug 19. [Epub ahead of print] |
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Protease-Activated Receptor 2 Deficiency Reduces Cardiac Ischemia/Reperfusion Injury
Silvio Antoniak ; Mauricio Rojas ; Denise Spring ; Tara Bullard ; Edvard Verrier ; Burns Blaxall ; Nigel Mackman ; and Rafal Pawlinski Arteriosclerosis, Thrombosis, and Vascular Biology. 2010 Aug 19. [Epub ahead of print] |
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Calorie Restriction Prevents Hypertension and Cardiac Hypertrophy in the Spontaneously Hypertensive Rat
Vernon W. Dolinsky; Jude S. Morton; Tatsujiro Oka; Isabelle Robillard-Frayne; Mariel Bagdan; Gary D. Lopaschuk; Christine Des Rosiers; Kenneth Walsh; Sandra T. Davidge; and Jason R.B. Dyck Hypertension. 2010 Aug 9. [Epub ahead of print] |
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Protective Role of Peroxisome Proliferator-Activated Receptor-β/δ in Septic Shoc
Amar Kapoor1, Yasunori Shintani1, Massimo Collino2, Marcin F. Osuchowski3, Daniel Busch3, Nimesh S.A. Patel1, Bruno Sepodes4, Sara Castiglia2, Roberto Fantozzi2, David Bishop-Bailey1, Helder Mota-Filipe5, Muhammad M Yaqoob1, Ken Suzuki1, Soheyl Bahrami3, Beatrice Désvergne6, Jane A. Mitchell7 and Christoph Thiemermann1 American Journal of Respiratory and Critical Care Medicine. 2010 Aug 6. [Epub ahead of print] |
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Foxp1 coordinates cardiomyocyte proliferation through both cell-autonomous and nonautonomous mechanisms
Yuzhen Zhang1,2, Shanru Li1,2, Lijun Yuan1,2,3, Ying Tian1,2, Joel Weidenfeld1,2, Jifu Yang1,2, Feiyan Liu1,2, Ann L. Chokas1,2 and Edward E. Morrisey1,2,4,5 Genes & Development. 2010 Aug 6. [Epub ahead of print] |
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Angiotensin-Converting Enzyme 2 Suppresses Pathological Hypertrophy, Myocardial Fibrosis, and Cardiac Dysfunction
JiuChang Zhong MD, Ratnadeep Basu MD, Danny Guo BSc, Fung L. Chow MSc, Simon Byrns BSc, Manfred Schuster PhD, Hans Loibner PhD, Xiu-hua Wang PhD, Josef M. Penninger MD, Zamaneh Kassiri PhD, and Gavin Y. Oudit MD, PhD Circulation. 2010 Aug 2. [Epub ahead of print] |
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The importance of elastin to aortic development in mice
Jessica E. Wagenseil,1 Christopher H. Ciliberto,2 Russell H. Knutsen,2 Marilyn A. Levy,2 Attila Kovacs,3 and Robert P. Mecham2 American Journal of Physiology. Heart and Circulatory Physiology. 2010 Aug;299(2):H257-64. Epub 2010 May 21 |
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Enhanced basal contractility but reduced excitation-contraction coupling efficiency and ß-adrenergic reserve of hearts with increased Cav1.2 activity
Mingxin Tang,1 Xiaoying Zhang,1 Yingxin Li,1 Yinzheng Guan,1 Xiaojie Ai,1,4 Christopher Szeto,1 Hiroyuki Nakayama,2 Hongyu Zhang,1 Shuping Ge,3 Jeffery D. Molkentin,2 Steven R. Houser,1 and Xiongwen Chen1 American Journal of Physiology. Heart and Circulatory Physiology. 2010 Aug;299(2):H519-28. Epub 2010 Jun 11 |
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Guided Cardiopoiesis Enhances Therapeutic Benefit of Bone Marrow Human Mesenchymal Stem Cells in Chronic Myocardial Infarction
Atta Behfar, MD, PhD1, Satsuki Yamada, MD, PhD1, Ruben Crespo-Diaz, BS1, Jonathan J. Nesbitt, BS1, Lois A. Rowe, ASCP1, Carmen Perez-Terzic, MD, PhD1,2, Vinciane Gaussin, PhD3, Christian Homsy, MD3, Jozef Bartunek, MD, PhD4 and Andre Terzic, MD, PhD1 Journal of the American College of Cardiology (JACC). 2010 Aug. [Epub ahead of print] |
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Murine echocardiography and ultrasound imaging
A Pistner, S Belmonte, T Coulthard, and B Blaxall Journal of Visualized Experiments : JoVE 2010 Aug 8;(42). pii: 2100 |
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High-Throughput Doppler Toolbox for Preclinical Drug Development
Karim Azer1, Michael C. Desiderio1, Christopher Tong2, Michelle Bunzel3, Barry R. Campbell3, Diane Shevell4, Matthew Walker III3 Journal of the Association for Laboratory Automation (JALA). 2010 Aug; vol.15 issue 4, 287-296 |
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Sphingosine-1-Phosphate–Dependent Activation of p38 MAPK Maintains Elevated Peripheral Resistance in Heart Failure Through Increased Myogenic Vasoconstriction
Judith Hoefer ; M. Ali Azam ; Jeffrey T.E. Kroetsch ; Howard Leong Poi ; M. Abdul Momen ; Julia Voigtlaender-Bolz ; Elias Q. Scherer ; Anja Meissner ; Steffen-Sebastian Bolz ; and Mansoor Husain Circulation Research. 2010 Jul 29. [Epub ahead of print] |
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Intracardiac Injection of AdGRK5-NT Reduces Left Ventricular Hypertrophy by Inhibiting NF-κB–Dependent Hypertrophic Gene Expression
Daniela Sorriento; Gaetano Santulli; Anna Fusco; Antonio Anastasio; Bruno Trimarco; and Guido Iaccarino Hypertension. 2010 Jul 26. [Epub ahead of print] |
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Small Molecule Disruption of Gβγ Signaling Inhibits the Progression of Heart Failure
Liam M. Casey ; Andrew R. Pistner ; Stephen L. Belmonte ; Dmitriy Migdalovich ; Olga Stolpnik ; Frances E. Nwakanma ; Gabriel Vorobiof ; Olga Dunaevsky ; Alessandra Matavel ; Coeli M.B. Lopes ; Alan V. Smrcka ; and Burns C. Blaxall Circulation Research. 2010 Jun 24. [Epub ahead of print] |
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Acute Humanin Therapy Attenuates Myocardial Ischemia and Reperfusion Injury in Mice
Radhika H. Muzumdar ; Derek M. Huffman ; John W. Calvert ; Saurabh Jha ; Yoni Weinberg ; Lingguang Cui ; Anjana Nemkal ; Gil Atzmon ; Laura Klein ; Susheel Gundewar ; Sang Yong Ji ; Madhav Lavu ; Benjamin L. Predmore ; and David J. Lefer Arteriosclerosis, Thrombosis, and Vascular Biology. 2010 Jul 22. [Epub ahead of print] |
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The murine angiotensin II-induced abdominal aortic aneurysm model: rupture risk and inflammatory progression patterns
Richard Y . Cao 1, Tim St. Amand 1, Matthew D . Ford 1, Ugo Piomelli 1 and Colin D. Funk 1 Frontiers in Pharmacotherapy of Inflammation. 2010 Jul 14. [Epub ahead of print] |
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Treatment with Docosahexaenoic Acid, but Not Eicosapentaenoic Acid, Delays Ca2+-Induced Mitochondria Permeability Transition in Normal and Hypertrophied Myocardium
Ramzi J. Khairallah, Karen M. O\'Shea, Bethany H. Brown, Nishanth Khanna, Christine Des Rosiers and William C. Stanley The journal of pharmacology and experimental therapeutics. 2010 Jul 12. [Epub ahead of print] |
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Genetic inhibition of PKA phosphorylation of RyR2 prevents dystrophic cardiomyopathy
Satyam Sarma1,2, Na Li1, Ralph J. van Oort1, Corey Reynolds1, Darlene G. Skapura1, and Xander H. T. Wehrens1,2 Proceedings of the National Academy of Sciences of the United States of America. 2010 Jul 6. [Epub ahead of print] |
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Myocardial knockdown of mRNA-stabilizing protein HuR attenuates post-MI inflammatory response and left ventricular dysfunction in IL-10-null mice
Prasanna Krishnamurthy, Erin Lambers, Suresh Verma, Tina Thorne, Gangjian Qin, Douglas W. Losordo, and Raj Kishore The FASEB Journal. 2010 Jul;24(7):2484-94. Epub 2010 Mar 10 |
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An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria
Brandon S.J. Davies1, Richard H. Barnes, II1, Yiping Tu1, Shuxun Ren2, Douglas A. Andres4, H. Peter Spielmann4, Jan Lammerding5, Yibin Wang1,2, Stephen G. Young1,3 and Loren G. Fong1 Human Molecular Genetics. 2010 Jul 1;19(13):2682-94. Epub 2010 Apr 26 |
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Alterations in membrane type-1 matrix metalloproteinase abundance after the induction of thoracic aortic aneurysm in a murine model
Jeffrey A. Jones,1,2 Jean Marie Ruddy,1 Shenikqua Bouges,1 Juozas A. Zavadzkas,1 Theresa A. Brinsa,1 Robert E. Stroud,1 Rupak Mukherjee,1 Francis G. Spinale,1,2 and John S. Ikonomidis1 American Journal of Physiology. Heart and Circulatory Physiology. 2010 Jul;299(1):H114-24. Epub 2010 Apr 23 |
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CXCR4 blockade augments bone marrow progenitor cell recruitment to the neovasculature and reduces mortality after myocardial infarction
Kentaro Jujo1, Hiromichi Hamada1, Atsushi Iwakura1, Tina Thorne1, Haruki Sekiguchi1, Trevor Clarke1, Aiko Ito1, Sol Misener1, Toshikazu Tanaka1, Ekaterina Klyachko1, Koichi Kobayashi1, Jörn Tongers1,2, Jérôme Roncalli1, Yukio Tsurumi3, Nobuhisa Hagiwara3, and Douglas W. Losordo1 Proceedings of the National Academy of Sciences of the United States of America. 2010 Jun 15;107(24):11008-13. Epub 2010 Jun 1 |
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Erythropoietin Activates Mitochondrial Biogenesis and Couples Red Cell Mass to Mitochondrial Mass in the Heart
Martha S. Carraway ; Hagir B. Suliman ; W. Schuyler Jones ; Chien-Wen Chen ; Abdelwahid Babiker ; and Claude A. Piantadosi Circulation Research. 2010 Jun 11;106(11):1722-30. Epub 2010 Apr 15 |
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Silencing Nox4 in the Paraventricular Nucleus Improves Myocardial Infarction–Induced Cardiac Dysfunction by Attenuating Sympathoexcitation and Periinfarct Apoptosis
David W. Infanger ; Xian Cao ; Scott D. Butler ; Melissa A. Burmeister ; Yi Zhou ; John A. Stupinski ; Ram V. Sharma ; and Robin L. Davisson Circulation Research. 2010 Jun 11;106(11):1763-74. Epub 2010 Apr 22 |
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Long-Acting Phosphodiesterase-5 Inhibitor Tadalafil Attenuates Doxorubicin-Induced Cardiomyopathy without Interfering with Chemotherapeutic Effect
Saisudha Koka, Anindita Das, Shu-Guang Zhu, David Durrant, Lei Xi and Rakesh C. Kukreja The journal of pharmacology and experimental therapeutics. 2010 Jun 11. [Epub ahead of print] |
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Alterations of L-Type Calcium Current and Cardiac Function in CaMKIIδ Knockout Mice
Lin Xu ; Dongwu Lai ; Jun Cheng ; Hyun Joung Lim ; Thitima Keskanokwong ; Johannes Backs ; Eric N. Olson ; and Yanggan Wang Circulation Research. 2010 Jun 10. [Epub ahead of print] |
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Pharmacogenomic, Physiological, and Biochemical Investigations on Safety and Efficacy Biomarkers Associated with the Peroxisome Proliferator-Activated Receptor-? Activator Rosiglitazone in Rodents: A Translational Medicine Investigation
Xinkang Wang, Xiaorong Liu, Yutian Zhan, Edward R. LaVallie, Liz DiBlasio-Smith, Lisa Collins-Racie, William M. Mounts, J. Lynn Rutkowski, Xin Xu, Ilia Goltsman, Zaid Abassi, Joseph Winaver and Giora Z. Feuerstein The journal of pharmacology and experimental therapeutics. 2010 Jun 2. [Epub ahead of print] |
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Heterogeneous ventricular sympathetic innervation, altered β adrenergic receptor expression, and rhythm instability in mice lacking p75 neurotrophin receptor
Christina U. Lorentz1, Eric N Alston2, J Todd Belcik2, Jonathan R. Lindner1, George D Giraud, and Beth A. Habecker2 American Journal of Physiology. Heart and Circulatory Physiology. 2010 Jun;298(6):H1652-60. Epub 2010 Feb 26 |
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Weight Loss in Obese C57BL/6 Mice Limits Adventitial Expansion of Established Angiotensin II-induced Abdominal Aortic Aneurysms
Sara B Police1, Kelly Putnam1, Sean E Thatcher2, Frederique Batifoulier-Yiannikouris1, Alan Daugherty1 and Lisa A Cassis1 American Journal of Physiology, Heart and Circulatory Physiology. 2010 Jun;298(6):H1932-8. Epub 2010 Mar 19 |
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Adrenal GRK2 lowering is an underlying mechanism for the beneficial sympathetic effects of exercise training in heart failure
Giuseppe Rengo1, Dario Leosco2, Carmela Zincarelli3, Massimo marchese3, Graziamaria Corbi4, Daniela Liccardo3, Amelia Filippelli5, Nicola Ferrara4, Michael P. Lisanti6, Walter J. Koch6 and Anastasios Lymperopoulos7 American Journal of Physiology, Heart and Circulatory Physiology. 2010 Jun;298(6):H2032-8. Epub 2010 Mar 19 |
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Involvement of Reductive Stress in the Cardiomyopathy in Transgenic Mice With Cardiac-Specific Overexpression of Heat Shock Protein 27
Xia Zhang; Xiaoyan Min; Chuanfu Li; Ivor J. Benjamin; Bo Qian; Xiaojin Zhang; Zhengnian Ding; Xiang Gao; Yuzhen Yao; Yujie Ma; Yunling Cheng; and Li Liu Hypertension. 2010 Jun;55(6):1412-7. Epub 2010 May 3 |
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Treatment of Heart Failure by a Methanocarba Derivative of Adenosine Monophosphate: Implication for a Role of Cardiac Purinergic P2X Receptors
Si-Yuan Zhou, Mohammed Mamdani, Khaled Qanud, Jian-Bing Shen, Achilles J. Pappano, T. Santhosh Kumar, Kenneth A. Jacobson, Thomas Hintze, Fabio A. Recchia, and Bruce T. Liang The journal of pharmacology and experimental therapeutics. 2010 Jun;333(3):920-8. Epub 2010 Mar 3 |
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Effects of cardiac-restricted overexpression of the A2A adenosine receptor on adriamycin-induced cardiotoxicity
Eman A. Hamad, Xue Li, Jianliang Song, Xue-Qian Zhang, Valerie Myers, Hajime Funakoshi, Jin Zhang, JuFang Wang, Jifen Li, David Swope, Ashley Madonick, John Farber, Glenn L. Radice, Joseph Y. Cheung, Tung O. Chan, and Arthur M. Feldman American Journal of Physiology. Heart and Circulatory Physiology. 2010 Jun;298(6):H1738-47. Epub 2010 Apr 2 |
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A causal relationship between shear stress and atherosclerotic lesions in apolipoprotein E knockout mice assessed by ultrasound biomicroscopy
Shi Fang Ding1,2, Mei Ni1, Xiao Ling Liu1, Li Hang Qi1, Mei Zhang1, Chun Xi Liu1, Ying Wang1, Hui Xia Lv1, and Yun Zhang1 American Journal of Physiology. Heart and Circulatory Physiology. 2010 Jun;298(6):H2121-9. Epub 2010 Apr 9 |
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Facilitation of murine cardiac L-type Cav1.2 channel is modulated by Calmodulin kinase II–dependent phosphorylation of S1512 and S1570
Anne Blaich1, Andrea Welling1,2, Stefanie Fischer1, Jörg Werner Wegener1, Katharina Köstner1, Franz Hofmann1,2,3, and Sven Moosmang1,2 Proceedings of the National Academy of Sciences of the United States of America. 2010 Jun 1;107(22):10285-9. Epub 2010 May 17 |
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Role of CaMKIIδ phosphorylation of the cardiac ryanodine receptor in the force frequency relationship and heart failure
Alexander Kushnir1, Jian Shan1, Matthew J. Betzenhauser1, Steven Reiken1, and Andrew R. Marks1,2 Proceedings of the National Academy of Sciences of the United States of America. 2010 Jun 1;107(22):10274-9. Epub 2010 May 17 |
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Effects of adiponectin deficiency on structural and metabolic remodeling in mice subjected to pressure overload
Karen M. O'Shea,1,2 David J. Chess,2 Ramzi J. Khairallah,2 Sharad Rastogi,3 Peter A. Hecker,2 Hani N. Sabbah,3 Kenneth Walsh,4 and William C. Stanley1,2 American Journal of Physiology. Heart and Circulatory Physiology. 2010 Jun;298(6):H1639-45. Epub 2010 Mar 26 |
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The bHLH transcription factor CHF1/Hey2 regulates susceptibility to apoptosis and heart failure after pressure overload
Yonggang Liu, Man Yu, Ling Wu, and Michael T. Chin American Journal of Physiology. Heart and Circulatory Physiology. 2010 Jun;298(6):H2082-92. Epub 2010 Apr 9 |
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Magnetic Targeting Enhances Engraftment and Functional Benefit of Iron-Labeled Cardiosphere-Derived Cells in Myocardial Infarction
Ke Cheng ; Tao-Sheng Li ; Konstantinos Malliaras ; Darryl Davis ; Yiqiang Zhang ; and Eduardo Marbán Circulation Research. 2010 May 28;106(10):1570-81. Epub 2010 Apr 8 |
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Interleukin-17A Is Dispensable for Myocarditis but Essential for the Progression to Dilated Cardiomyopathy
G. Christian Baldeviano ; Jobert G. Barin ; Monica V. Talor ; Sachin Srinivasan ; Djahida Bedja ; Donfeng Zheng ; Kathleen Gabrielson ; Yoichiro Iwakura ; Noel R. Rose ; and Daniela Cihakova Circulation Research. 2010 May 28;106(10):1646-55. Epub 2010 Apr 8 |
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Adrenergic Receptor Blockade Reverses Right Heart Remodeling and Dysfunction in Pulmonary Hypertensive Rats
Harm J Bogaard, Ramesh Natarajan, Shiro Mizuno, Antonio Abbate1, Philip J. Chang, Vinh Q Chau1, Nicholas N Hoke1, Donatas Kraskauskas, Michael Kasper2, Fadi N Salloum1, Norbert F Voelkel American Journal of Respiratory and Critical Care Medicine. 2010 May 27. [Epub ahead of print] |
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Mechanism of Improved Cardiac Function After Bone Marrow Mononuclear Cell Therapy. Role of Cardiovascular Lineage Commitment
Chang-Hwan Yoon MD, Masamichi Koyanagi MD, PhD, Kazuma Iekushi MD, Florian Seeger MD, Carmen Urbich PhD, Andreas M. Zeiher MD, and Stefanie Dimmeler PhD Circulation. 2010 May 11;121(18):2001-11. Epub 2010 Apr 26 |
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Elevated myocardial Na+/H+ exchanger isoform 1 activity elicits gene expression that leads to cardiac hypertrophy
Jin Xue 1, Fatima Mraiche 3, Dan Zhou 1, Morris Karmazyn 4, Tatsujiro Oka 3, Larry Fliegel 3, and Gabriel G. Haddad 1,2,5 Physiological Genomics. 2010 May 11. [Epub ahead of print] |
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Exercise Training Prevents the Exaggerated Exercise Pressor Reflex in Rats with Chronic Heart Failure
Han-Jun Wang1, Yan-Xia Pan1, Wei-Zhong Wang2, Lie Gao3, Matthew C. Zimmerman1, Irving H. Zucker1, and Wei Wang1 Journal of Applied Physiology. 2010 May;108(5):1365-75. Epub 2010 Feb 25 |
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Trimetazidine, Administered at the Onset of Reperfusion, Ameliorates Myocardial Dysfunction and Injury by Activation of p38 Mitogen-Activated Protein Kinase and Akt Signaling
Mahmood Khan, Sarath Meduru, Mahmoud Mostafa, Saniya Khan, Kà lmà n Hideg and Periannan Kuppusamy The journal of pharmacology and experimental therapeutics. 2010 May;333(2):421-9. Epub 2010 Feb 18 |
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miR-9 and NFATc3 regulate myocardin in cardiac hypertrophy
Kun Wang, Bo Long, Jing Zhou and Pei-Feng Li The Journal of Biological Chemistry. 2010 Apr 16;285(16):11903-12. Epub 2010 Feb 21 |
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Elevated Cytosolic Na+ Increases Mitochondrial Formation of Reactive Oxygen Species in Failing Cardiac Myocytes
Michael Kohlhaas, PhD; Ting Liu, PhD; Andreas Knopp, PhD; Tanja Zeller, PhD; Mei Fang Ong, PhD; Michael Böhm, MD; Brian O'Rourke, PhD; Christoph Maack, MD Circulation. 2010 Apr 13;121(14):1606-13. Epub 2010 Mar 29 |
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Klf15 Deficiency Is a Molecular Link Between Heart Failure and Aortic Aneurysm Formation
Saptarsi M. Haldar1, Yuan Lu1, Darwin Jeyaraj1, Daiji Kawanami1, Yingjie Cui1, Sam J. Eapen1, Caili Hao1, Yan Li2, Yong-Qiu Doughman3, Michiko Watanabe3, Koichi Shimizu4, Helena Kuivaniemi5, Junichi Sadoshima6, Kenneth B. Margulies2, Thomas P. Cappola2 and Mukesh K. Jain1 Science Translational Medicine. 2010 Apr 7;2(26):26ra26 |
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Oxidative Stress Regulates Left Ventricular PDE5 Expression in the Failing Heart
Zhongbing Lu PhD, Xin Xu MD, PhD, Xinli Hu PhD, Sangjin Lee MD, Jay H. Traverse MD, Guangshuo Zhu MD, John Fassett PhD, Yi Tao BS, Ping Zhang PhD, Cris dos Remedios PhD, Marc Pritzker MD, Jennifer L. Hall PhD, Daniel J. Garry MD, PhD, and Yingjie Chen MD, PhD Circulation. 2010 Apr 6;121(13):1474-83. Epub 2010 Mar 22 |
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Pkd1 transgenic mice: adult model of polycystic kidney disease with extrarenal and renal phenotypes
Almira Kurbegovic1, Olivier Côté1, Martin Couillard1, Christopher J. Ward2, Peter C. Harris2 and Marie Trudel1 Human Molecular Genetics. 2010 Apr 1;19(7):1174-89. Epub 2010 Jan 6 |
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Accelerated Development of Pressure Overload–Induced Cardiac Hypertrophy and Dysfunction in an RyR2-R176Q Knockin Mouse Model
Ralph J. van Oort; Jonathan L. Respress; Na Li; Corey Reynolds; Angela C. De Almeida; Darlene G. Skapura; Leon J. De Windt; and Xander H.T. Wehrens Hypertension. 2010 Apr;55(4):932-8. Epub 2010 Feb 15 |
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Detection of Left Ventricular Hypertrophy in Rats Administered a Peroxisome Proliferator–Activated Receptor α/β Dual Agonist Using Natriuretic Peptides and Imaging
Steven K. Engle1, Philip F. Solter2, Kelly M. Credille1, Christopher M. Bull1, Stephanie Adams1, Michael J. Berna1, Albert E. Schultze1, Emily C. Rothstein1, Michael D. Cockman1, Michael L. Pritt1, Hong Liu1, Yuefeng Lu1, Alan Y. Chiang1 and David E. Watson1 Toxicological Sciences. 2010 Apr;114(2):183-92. Epub 2009 Dec 31 |
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Alterations of pre- and postsynaptic noradrenergic signaling in a rat model of adriamycin-induced cardiotoxicity
Miran Kenk1, 2, James T. Thackeray1, 2, Stephanie L. Thorn1, 2, Karan Dhami3, Benjamin J. Chow1, Kathy J. Ascah4, Jean N. DaSilva1, 2 and Rob S. Beanlands1, 2 Journal of Nuclear Cardiology. 2010 Apr;17(2):254-63. Epub 2010 Feb 25 |
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Macrophage Adiponectin Expression Improves Insulin Sensitivity and Protects Against Inflammation and Atherosclerosis
Nanlan Luo1, Jian Liu1, B. Hong Chung1, Qinglin Yang1, Richard L. Klein2, W. Timothy Garvey1,3 and Yuchang Fu1 Diabetes. 2010 Apr;59(4):791-9 |
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Interleukin-1ß modulation using a genetically engineered antibody prevents adverse cardiac remodelling following acute myocardial infarction in the mouse
Antonio Abbate1,2, Benjamin W. Van Tassell1,2,3, Ignacio M. Seropian1,2,3, Stefano Toldo1,2, Roshanak Robati1, Amit Varma1, Fadi N. Salloum1, Lisa Smithson2 and Charles A. Dinarello4 European Journal of Heart Failure. 2010 Apr;12(4):319-22 |
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Echocardiographic Assessment of Cardiac Morphology and Function in Xenopus
Heather L Bartlett,1 Robert B Escalera,II1 Sonali S Patel,1 Elesa W Wedemeyer,1 Kenneth A Volk,1 Jamie L Lohr,2 and Benjamin E Reinking1 Comparative Medicine. 2010;60(2):107-113 |
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Cardiac hypertrophy is not amplified by deletion of cGMP-dependent protein kinase I in cardiomyocytes
Robert Lukowski1,2,3, Sergei D. Rybalkin1,4,5, Florian Loga1,4, Veronika Leiss1,4, Joseph A. Beavo1,4,5, and Franz Hofmann1,4 Proceedings of the National Academy of Sciences of the United States of America. 2010 Mar 23;107(12):5646-51. Epub 2010 Mar 8 |
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Metformin attenuates cardiac fibrosis by inhibiting the TGFß1–Smad3 signalling pathway
Han Xiao1,4, Xiaowei Ma1,4, Wei Feng1,4, Yongnan Fu1,4, Zhizhen Lu1,4, Ming Xu1,4, Qiang Shen3,4, Yi Zhu2,4 and Youyi Zhang1,4 Cardiovascular Research. 2010 Mar 23. [Epub ahead of print] |
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Aortic Regurgitation Dramatically Alters the Distribution of Atherosclerotic Lesions and Enhances Atherogenesis in Mice
Yu-Qing Zhou ; Su-Ning Zhu ; F. Stuart Foster ; Myron I. Cybulsky ; and R. Mark Henkelman Arteriosclerosis, Thrombosis, and Vascular Biology. 2010 Jun;30(6):1181-8. Epub 2010 Mar 18 |
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Plasminogen activator inhibitor-1 (PAI-1) is cardioprotective in mice by maintaining microvascular integrity and cardiac architecture
Zhi Xu1,2, Francis J. Castellino1,2, and Victoria A. Ploplis1,2 Blood. 2010 Mar 11;115(10):2038-47. Epub 2009 Dec 15 |
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Involvement of Phosphoinositide 3-Kinase γ in Angiogenesis and Healing of Experimental Myocardial Infarction in Mice
Mauro Siragusa ; Rajesh Katare ; Marco Meloni ; Federico Damilano ; Emilio Hirsch ; Costanza Emanueli ; and Paolo Madeddu Circulation Research. 2010 Mar 5;106(4):757-68. Epub 2010 Jan 7 |
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TIMP2 Deficiency Accelerates Adverse Post–Myocardial Infarction Remodeling Because of Enhanced MT1-MMP Activity Despite Lack of MMP2 Activation
Vijay Kandalam ; Ratnadeep Basu ; Thomas Abraham ; Xiuhua Wang ; Paul D. Soloway ; Diane M. Jaworski ; Gavin Y. Oudit ; and Zamaneh Kassiri Circulation Research. 2010 Mar 5;106(4):796-808. Epub 2010 Jan 7 |
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Preconditioning by toll-like receptor 2 agonist Pam3CSK4 reduces CXCL1-dependent leukocyte recruitment in murine myocardial ischemia/reperfusion injury
Mersmann, Jan MD; Berkels, Reinhard PhD; Zacharowski, Paula PhD; Tran, Nguyen PhD; Koch, Alexander MD; Iekushi, Kazuma MD; Dimmeler, Stefanie PhD; Granja, Tiago F. MA; Boehm, Olaf MD; Claycomb, William C. PhD; Zacharowski, Kai MD, PhD, FRCA Critical Care Medicine. 2010 Mar;38(3):903-909 |
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Left-sided cardiac valvulitis in tristetraprolin-deficient mice: the role of tumor necrosis factor α
Sanjukta Ghosh1, Mark J. Hoenerhoff2, Natasha Clayton2, Page Myers3, Deborah J. Stumpo1, Robert R. Maronpot2 and Perry J. Blackshear1,4 The American Journal of Pathology. 2010 Mar;176(3):1484-93. Epub 2010 Jan 21 |
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Noninvasive Assessment of Murine Pulmonary Arterial Pressure: Validation and Application to Models of Pulmonary Hypertension
Hélène B. Thibault, MD, PhD; Baptiste Kurtz, MD; Michael J. Raher, BS; Rahamthulla S. Shaik, MS; Aaron Waxman, MD, PhD; Geneviève Derumeaux, MD, PhD; Elkan F. Halpern, PhD; Kenneth D. Bloch, MD and Marielle Scherrer-Crosbie, MD, PhD Circulation: Cardiovascular Imaging. 2010 Mar;3(2):157-63. Epub 2009 Dec 31 |
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Functional recovery of diabetic mouse hearts by glutaredoxin-1 gene therapy: role of Akt-FoxO-signaling network
I Lekli1,2, S Mukherjee1, D Ray1, N Gurusamy1, YH Kim1,3, A Tosaki2, RM Engelman1, Y-S Ho4 and DK Das1 Gene Therapy. 2010 Feb 25. [Epub ahead of print] |
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High-intensity exercise training in mice with cardiomyocyte-specific disruption of Serca2
Madelene Ericsson1, Kristin B. Andersson2, Brage H. Amundsen3, Sverre H. Torp3, Ivar Sjaastad4, Geir Christensen5, Ole M. Sejersted6, and Oyvind Ellingsen3 Journal of Applied Physiology. 2010 Feb 18. [Epub ahead of print] |
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In Vivo Assessment of the Effects of Ginsenoside Rb1 on Intimal Hyperplasia in ApoE Knockout Mice
Hong Chai M.D., Ph.D., Geoff Schultz M.D., Kamran Aghaie M.D. and Wei Zhou M.D. Journal of Surgical Research. 2010 Feb 11. [Epub ahead of print] |
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Reduced expression of Cx43 attenuates ventricular remodeling after myocardial infarction via impaired TGF-ß signaling
Yan Zhang1,2, Hongtao Wang3, Attila Kovacs1,2, Evelyn M. Kanter1,2, and Kathryn A. Yamada1,2 American Journal of Physiology, Heart and Circulatory Physiology. 2010 Feb;298(2):H477-87. Epub 2009 Dec 4 |
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Molecular Imaging of Myocardial and Vascular Disorders With Ultrasound
Jonathan R. Lindner, MD JACC. Cardiovascular Imaging. 2010 Feb;3(2):204-211 |
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Cardiomyocyte PDGFR-ß signaling is an essential component of the mouse cardiac response to load-induced stress
Vishnu Chintalgattu,1 Di Ai,1 Robert R. Langley,2 Jianhu Zhang,1 James A. Bankson,3 Tiffany L. Shih,1 Anilkumar K. Reddy,4 Kevin R. Coombes,5 Iyad N. Daher,1 Shibani Pati,6 Shalin S. Patel,1 Jennifer S. Pocius,4 George E. Taffet,4 L. Maximillian Buja,7 Mark L. Entman,4 and Aarif Y. Khakoo1 The Journal of Clinical Investigation. 2010 Feb 1;120(2):472-84. Epub 2010 Jan 11 |
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High-Frequency Ultrasound Assessment of the Murine Heart From Embryo Through to Juvenile
Niamh Corrigan1, Derek P. Brazil2, and Fionnuala M. Auliffe3 Reproductive Sciences. 2010 Feb;17(2):147-57. Epub 2009 Oct 20 |
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Exogenous NAD Blocks Cardiac Hypertrophic Response via Activation of the SIRT3-LKB1-AMP-activated Kinase Pathway
Vinodkumar B. Pillai1, Nagalingam R. Sundaresan1, Gene Kim2, Madhu Gupta4, Senthilkumar B. Rajamohan1, Jyothish B. Pillai1, Sadhana Samant1, P. V. Ravindra1, Ayman Isbatan1, and Mahesh P. Gupta1,3 The Journal of Biological Chemistry. 2010 Jan 29; 285(5):3133-3144 |
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Direct Regulation of Myocardial Triglyceride Metabolism by the Cardiomyocyte Circadian Clock
Ju-Yun Tsai1, Petra C. Kienesberger2, Thomas Pulinilkunnil2, Mary H. Sailors1, David J. Durgan3, Carolina Villegas-Montoya1, Anil Jahoor1, Raquel Gonzalez1, Merissa E. Garvey1, Brandon Boland1, Zachary Blasier1, Tracy A. McElfresh5, Vijayalakshmi Nannegari1, Chi-Wing Chow6, William C. Heird1, Margaret P. Chandler5, Jason R. B. Dyck2, Molly S. Bray4, and Martin E. Young3 The Journal of Biological Chemistry. 2010 Jan 29; 285(5):2918-2929 |
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Ventricular Rotation Is Independent of Cardiac Looping: A Study in Mice With Situs Inversus Totalis Using Speckle-Tracking Echocardiography
Lowell H. Frank MDa,c, Qing Yu MDa, Richard Francis PhDa, Xin Tian PhDb, Rajeev Samtania, David J. Sahn MDd, Linda Leatherbury MDa,c and Cecilia W. Lo PhDa,e Journal of the American Society of Echocardiography. 2010 Jan 22. [Epub ahead of print] |
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Relative Roles of Direct Regeneration Versus Paracrine Effects of Human Cardiosphere-Derived Cells Transplanted Into Infarcted Mice
Isotta Chimenti ; Rachel Ruckdeschel Smith ; Tao-Sheng Li ; Gary Gerstenblith ; Elisa Messina ; Alessandro Giacomello ; and Eduardo Marbán Circulation Research. 2010 Jan 20. [Epub ahead of print] |
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Peroxisome Proliferator-Activated Receptor δ Is an Essential Transcriptional Regulator for Mitochondrial Protection and Biogenesis in Adult Heart.
Peiyong Wang ; Jian Liu ; Yuquan Li ; Sijie Wu ; Jinwen Luo ; Huan Yang ; Ramasamy Subbiah ; John Chatham ; Olga Zhelyabovska ; and Qinglin Yang Circulation Research. 2010 Jan 14. [Epub ahead of print] |
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Cardioprotective effects of growth hormone-releasing hormone agonist after myocardial infarction
Rosemeire M. Kanashiro-Takeuchi1, Konstantinos Tziomalos1, Lauro M. Takeuchi1, Adriana V. Treuer1, Guillaume Lamirault1, Raul Dulce1, Michael Hurtado1, Yun Song1, Norman L. Block2,3,4, Ferenc Rick2,3, Anna Klukovits2,3, Qinghua Hu1, Jozsef L. Varga2,4, Andrew V. Schally2,3,4, and Joshua M. Hare1,5 Proceedings of the National Academy of Sciences of the United States of America 2010 Feb 9;107(6):2604-9. Epub 2010 Jan 21 |
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Heart-specific overexpression of CUGBP1 reproduces functional and molecular abnormalities of myotonic dystrophy type 1
Misha Koshelev1, Satyam Sarma2,3, Roger E. Price5, Xander H.T. Wehrens2,3 and Thomas A. Cooper1,4 Human Molecular Genetics. 2010 Jan 8. [Epub ahead of print] |
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Altered Cardiac Function and Ventricular Septal Defect in Avian Embryos Exposed to Low-Dose Trichloroethylene
Echoleah S. Rufer1,2, Timothy A. Hacker3, George R. Flentke2, Victoria J. Drake4, Matthew J. Brody1,2, John Lough5 and Susan M. Smith1,2 Toxicological Sciences. 2010 [Epub ahead of print] 2009 Nov 12. |
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Spontaneous Adult-Onset Pulmonary Arterial Hypertension Attributable to Increased Endothelial Oxidative Stress in a Murine Model of Hereditary Hemorrhagic Telangiectasia
Mourad Toporsian ; Mirjana Jerkic ; Yu-Qing Zhou ; Mohammed G. Kabir ; Lisa X. Yu ; Brendan A. S. McIntyre ; Adrienne Davis ; Yu Jing Wang ; Duncan J. Stewart ; Jaques Belik ; Mansoor Husain ; Mark Henkelman ; and Michelle Letarte Arteriosclerosis, Thrombosis, and Vascular Biology. 2010 Mar;30(3):509-17. Epub 2009 Dec 30 |
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MEF2 transcriptional activity maintains mitochondrial adaptation in cardiac pressure overload
Hamid el Azzouzi1,2, Ralph J. van Oort2, Roel van der Nagel2, Wim Sluiter3, Martin W. Bergmann4 and Leon J. De Windt1,2 European Journal of Heart Failure. 2010 Jan;12(1):4-12 |
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Oral Glutamine Protects against Acute Doxorubicin-Induced Cardiotoxicity of Tumor-Bearing Rats
Valentina K. Todorova1, Yihong Kaufmann3, Leah Hennings2, and V. Suzanne Klimberg1,2 The Journal of Nutrition. 2010 Jan;140(1):44-48. Epub 2009 Nov 4 |
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Nitrite Potently Inhibits Hypoxic and Inflammatory Pulmonary Arterial Hypertension and Smooth Muscle Proliferation via Xanthine Oxidoreductase–Dependent Nitric Oxide Generation
Brian S. Zuckerbraun MD, Sruti Shiva PhD, Emeka Ifedigbo BA, Michael A. Mathier MD, Kevin P. Mollen MD, Jayashree Rao BS, Philip M. Bauer PhD, Justin J.W. Choi , Erin Curtis BA, Augustine M.K. Choi MD, and Mark T. Gladwin MD Circulation. 2010 Jan 5;121(1):98-109. Epub 2009 Dec 21 |
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Anti-Fas Gene Therapy Prevents Doxorubicin-Induced Acute Cardiotoxicity through Mechanisms Independent of Apoptosis
Shusaku Miyata1, Genzou Takemura1, Ken-ichiro Kosai2, Tomoyuki Takahashi3, Masayasu Esaki1, Longhu Li1, Hiromitsu Kanamori1, Rumi Maruyama1, Kazuko Goto1, Akiko Tsujimoto1, Toshiaki Takeyama1, Tomonori Kawaguchi1, Takamasa Ohno4, Kazuhiko Nishigaki1, Takako Fujiwara5, Hisayoshi Fujiwara1 and Shinya Minatoguchi1 The American Journal of Pathology. 2010 [Epub ahead of print] 2009 Dec 24. |
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The effects of VEGF-R1 and VEGF-R2 ligands on angiogenic responses and left ventricular function in mice
Jenni Huusko1, Mari Merentie1, Marike H. Dijkstra1, Minttu-Maria Ryhänen1, Henna Karvinen1, Tuomas T. Rissanen1, Maarten Vanwildemeersch2,3, Marja Hedman4, Jukka Lipponen5, Suvi E. Heinonen1, Ulf Eriksson2,3, Masabumi Shibuya6 and Seppo Ylä-Herttuala1,7 Cardiovascular Research. 2010 [Epub ahead of print] 2009 Dec 28 |
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Cardiac-specific Deletion of LKB1 Leads to Hypertrophy and Dysfunction
Yasumasa Ikeda1, Kaori Sato1, David R. Pimentel2, Flora Sam3, Reuben J. Shaw4, Jason R. B. Dyck5, and Kenneth Walsh1 The Journal of Biological Chemistry. 2009 Dec 18;284(51):35839-35849 |
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Combination therapy with albumin and pentoxifylline protects against acute kidney injury during endotoxemic shock in mice
Bansal, Shweta; Wang, Wei; Falk, Sandor; Schrier, Robert Renal Failure. 2009;31(9):848-54 |
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Dynamic Correction for Parallel Conductance, GP, and Gain Factor, α, in Invasive Murine Left Ventricular Volume Measurements
John E. Porterfield1, Anil T.G. Kottam1, Karthik Raghavan1, Daniel Escobedo2, James T. Jenkins3, Erik R. Larson4, Rodolfo Javier Trevino5, Jonathan W. Valvano1, John A. Pearce1, and Marc D. Feldman3 The Journal of Applied Physiology. 2009 Dec;107(6):1693-703. Epub 2009 Aug 20 |
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Dysferlin Deficiency and the Development of Cardiomyopathy in a Mouse Model of Limb-Girdle Muscular Dystrophy 2B
Thomas H. Chase, Gregory A. Cox, Lisa Burzenski, Oded Foreman and Leonard D. Shultz The American Journal of Pathology. 2009 Dec;175(6):2299-308. Epub 2009 Oct 29 |
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PKC inhibition ameliorates the cardiac phenotype in a mouse model of myotonic dystrophy type 1
Guey-Shin Wang,1 Muge N. Kuyumcu-Martinez,1 Satyam Sarma,2,3 Nitin Mathur,2,3 Xander H.T. Wehrens,2,3 and Thomas A. Cooper1,4 The Journal of Clinical Investigation. 2009 Dec;119(12):3797-806. Epub 2009 Nov 9 |
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Changes in left ventricular function and remodeling after myocardial infarction in hypothyroid rats
Yue-Feng Chen1, Rebecca A Redetzke1, Suleman Said, April J Beyer1, and A Martin Gerdes1 American Journal of Physiology. Heart and Circulatory Physiology. 2010 Jan;298(1):H259-62. Epub 2009 Nov 20 |
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Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms
Giulia Mearini1, Christina Gedicke1, Saskia Schlossarek1, Christian C. Witt2, Elisabeth Krämer1, Peirang Cao3, Marcelo D. Gomes4, Stewart H. Lecker3, Siegfried Labeit2, Monte S. Willis5, Thomas Eschenhagen1 and Lucie Carrier1,6,7 Cardiovascular Research. 2010 Jan 15;85(2):357-66. Epub 2009 Oct 22 |
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Chronic Pulmonary Artery Pressure Elevation Is Insufficient to Explain Right Heart Failure
Harm J. Bogaard, MD, PhD; Ramesh Natarajan, PhD; Scott C. Henderson, PhD; Carlin S. Long, MD; Donatas Kraskauskas, DVM; Lisa Smithson, BSc; Ramzi Ockaili, PhD; Joe M. McCord, PhD; Norbert F. Voelkel, MD Circulation. 2009 Nov 17;120(20):1951-60. Epub 2009 Nov 2 |
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Vascular Endothelial-Specific Dimethylarginine Dimethylaminohydrolase-1-Deficient Mice Reveal That Vascular Endothelium Plays an Important Role in Removing Asymmetric Dimethylarginine
Xinli Hu PhD, Xin Xu MD, PhD, Guangshuo Zhu MD, Dorothee Atzler MS, Masumi Kimoto PhD, Ju Chen PhD, Edzard Schwedhelm PhD, Nicole Lüneburg PhD, Rainer H. Böger MD, Ping Zhang PhD, and Yingjie Chen MD, PhD Circulation. 2009 Dec 1;120(22):2222-9. Epub 2009 Nov 16 |
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Adiponectin. An Indispensable Molecule in Rosiglitazone Cardioprotection Following Myocardial Infarction
Ling Tao; Yajing Wang; Erhe Gao; Hangxiang Zhang; Yuexing Yuan; Wayne B. Lau; Lawrence Chan; Walter J. Koch; and Xin L. Ma Circulation Research. 2009 Nov 16. [Epub ahead of print] |
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c-Jun DNAzymes Inhibit Myocardial Inflammation, ROS Generation, Infarct Size, and Improve Cardiac Function After Ischemia-Reperfusion Injury
Xiao Luo ; Hong Cai ; Jun Ni ; Ravinay Bhindi ; Harry C. Lowe ; and Colin N. Chesterman Arteriosclerosis, Thrombosis, and Vascular Biology. 2009 Nov;29(11):1836-42. Epub 2009 Jul 10 |
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Bone marrow-derived cells do not repair endothelium in a mouse model of chronic endothelial cell dysfunction
Tashera E. Perry1, Minjung Song1, Daryl J. Despres2, Soo Mi Kim3, Hong San4, Zu-Xi Yu5, Nalini Raghavachari6, Jurgen Schnermann3, Richard O. Cannon, III1 and Donald Orlic1 Cardiovascular Research. 2009 Nov 1;84(2):317-25. Epub 2009 Jul 3 |
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Endothelium-specific overexpression of human IC53 downregulates endothelial nitric oxide synthase activity and elevates systolic blood pressure in mice
Ming-Lei Zhuo1, Yue Huang1, Jing-Zhou Chen2, Li-Hong Sun1, Rui-Feng Yang1, Hou-Zao Chen1, Xiang Lv1, Hong-Liang Li1, Yu-Sheng Wei1, Guang Liu1, Ran Zhang1, Tie-Min Ma3, Hua Cai4,5, Ru-Tai Hui2, De-Pei Liu1, and Chih-Chuan Liang1 Cardiovascular Research. 2009 Nov 1;84(2):292-9. Epub 2009 Jun 18 |
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Periostin Is a Novel Factor in Cardiac Remodeling After Experimental and Clinical Unloading of the Failing Heart
William E. Stansfield, MD1, Nancy M. Andersen, MD1, Ru-Hang Tang, PhD1, Craig H. Selzman, MD1,2 The annals of thoracic surgery. 2009 Dec;88(6):1916-21 |
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Stimulation of Coronary Collateral Growth by Granulocyte Stimulating Factor. Role of Reactive Oxygen Species
Ana Catarina R. Carrão ; William M. Chilian; June Yun ; Christopher Kolz ; Petra Rocic ; Kerstin Lehmann ; Jeroen P.H.M. van den Wijngaard ; Pepijn van Horssen ; Jos A.E. Spaan ; Vahagn Ohanyan ; Yuh Fen Pung ; and Ivo Buschmann Arteriosclerosis, Thrombosis, and Vascular Biology. 2009 Nov;29(11):1817-22. Epub 2009 Jun 18 |
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Antioxidant Amelioration of Dilated Cardiomyopathy Caused by Conditional Deletion of NEMO/IKK{gamma} in Cardiomyocytes
P. Kratsios ; M. Huth ; L. Temmerman ; E. Salimova ; M. Al Banchaabouchi ; A. Sgoifo ; M. Manghi ; K. Suzuki ; N. Rosenthal; and F. Mourkioti Circulation Research. 2010 Jan 8;106(1):133-44. Epub 2009 Oct 22 |
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Adiponectin Deficiency, Diastolic Dysfunction, and Diastolic Heart Failure
Flora Sam, Toni-Ann S. Duhaney, Kaori Sato, Richard M. Wilson, Koji Ohashi, Saki Sono-Romanelli, Akiko Higuchi, Deepa S. De Silva, Fuzhong Qin, Kenneth Walsh, and Noriyuki Ouchi Endocrinology. 2010 Jan;151(1):322-31. Epub 2009 Oct 22 |
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Myocardin is required for cardiomyocyte survival and maintenance of heart function
Jianhe Huang1, Min Min Lu1, Lan Cheng1, Li-Jun Yuan1,2, Xiaoquing Zhu1, Andrea L. Stout1,3, Mary Chen1, Jian Li1, and Michael S. Parmacek1,4 Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2009 Nov 3;106(44):18734-9. Epub 2009 Oct 22 |
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Noninvasive Quantification and Optimization of Acute Cell Retention by In Vivo Positron Emission Tomography After Intramyocardial Cardiac-Derived Stem Cell Delivery
John Terrovitis, MD1, Riikka Lautamäki, MD, PhD4, Michael Bonios, MD2, James Fox, BS5, James M. Engles, MS, MBA4, Jianhua Yu, BS5, Michelle K. Leppo, BS2, Martin G. Pomper, MD, PhD5, Richard L. Wahl, MD4, Jurgen Seidel, PhD3, Benjamin M. Tsui, PhD5, Frank M. Bengel, MD4, M. Roselle Abraham, MD2 and Eduardo Marbán, MD, PhD1 Journal of the American College of Cardiology (JACC). 2009 Oct 20; 54(17):1619-1626 |
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Feasibility of Functional Cardiac MR Imaging in Mice Using A Clinical 3 Tesla Whole Body Scanner
Alexander C Bunck, Markus A Engelen, Bernhard Schnackenburg, Juliane Furkert, Christoph Bremer, Walter Heindel, Jorg Stypmann, and David Maintz Investigative Radiology. 2009 Oct 15. [Epub ahead of print] |
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Molecular Imaging of the Initial Inflammatory Response in Atherosclerosis. Implications for Early Detection of Disease
Beat A. Kaufmann ; Chad L. Carr ; J. Todd Belcik ; Aris Xie ; Qi Yue ; Scott Chadderdon ; Evan S. Caplan ; Jaspreet Khangura ; Sherry Bullens ; Stuart Bunting ; and Jonathan R. Lindner Arteriosclerosis, Thrombosis, and Vascular Biology. 2010 Jan;30(1):54-9. Epub 2009 Oct 15 |
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IL-18 binding protein-expressing mesenchymal stem cells improve myocardial protection after ischemia or infarction
Meijing Wang1, Jiangning Tan1, Yue Wang1, Kirstan K. Meldrum2, Charles A. Dinarello3 and Daniel R. Meldrum1,4,5 Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2009 Oct 13;106(41):17499-504. Epub 2009 Sep 25 |
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Mice Overexpressing Both Human Angiotensinogen and Human Renin as a Model of Superimposed Preeclampsia on Chronic Hypertension
Stéphanie Falcao, Ekatherina Stoyanova, Guy Cloutier, Roch L. Maurice, Jolanta Gutkowska, and Julie L. Lavoie Hypertension. 2009 Dec;54(6):1401-7. Epub 2009 Oct 12 |
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Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function
Ratnadeep Basu1,2, Gavin Y. Oudit2,3, Xiuhua Wang1,2, Liyan Zhang2,4, John R. Ussher2,4, Gary D. Lopaschuk2,4 and Zamaneh Kassiri1,2 American Journal of Physiology. Heart and Circulatory Physiology. 2009 Dec;297(6):H2096-108. Epub 2009 Oct 2 |
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Analysis of In Situ and Ex Vivo Vascular Endothelial Growth Factor Receptor Expression During Experimental Aortic Aneurysm Progression
Maureen M. Tedesco ; Masahiro Terashima ; Francis G. Blankenberg ; Zoia Levashova ; Joshua M. Spin ; Marina V. Backer ; Joseph M. Backer ; Mien Sho ; Eiketsu Sho ; Michael V. McConnell ; and Ronald L. Dalman Arteriosclerosis, Thrombosis, and Vascular Biology. 2009 Oct;29(10):1452-7. Epub 2009 Jul 2 |
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β1-Adrenergic Receptors Stimulate Cardiac Contractility and CaMKII Activation In Vivo and Enhance Cardiac Dysfunction Following Myocardial Infarction
ByungSu Yoo1, Anthony Lemaire2, Supachoke Mangmool2, Matthew J Wolf2, Antonio Curcio, Lan Mao2, and Howard A. Rockman2 American Journal of Physiology. Heart and Circulatory Physiology. 2009 Oct;297(4):H1377-86. Epub 2009 Jul 24 |
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ATP-Sensitive K+ Channel Knockout Induces Cardiac Proteome Remodeling Predictive of Heart Disease Susceptibility
D Kent Arrell, Jelena Zlatkovic, Garvan C Kane, Satsuki Yamada, and Andre Terzic Journal of Proteome Research. 2009 Oct;8(10):4823-34 |
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Postinfarction gene therapy with adenoviral vector expressing decorin mitigates cardiac remodeling and dysfunction
Longhu Li, Hideshi Okada, Genzou Takemura1, Ken-ichiro Kosai2, Hiromitsu Kanamori, Masayasu Esaki, Tomoyuki Takahashi2, Kazuko Goto, Akiko Tsujimoto, Rumi Maruyama, Itta Kawamura, Tomonori Kawaguchi, Toshiaki Takeyama, Takako Fujiwara, Hisayoshi Fujiwara3, and Shinya Minatoguchi American Journal of Physiology, Heart and Circulatory Physiology. 2009 Oct;297(4):H1504-13. Epub 2009 Aug 14 |
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Partial carotid ligation is a model of acutely induced disturbed flow, leading to rapid endothelial dysfunction and atherosclerosis
Douglas Nam1, Chih-Wen Ni2, Amir Rezvan1, Jin Suo3, Klaudia Budzyn, Alexander Llanos, David G Harrison4, Don Giddens5, and Hanjoong Jo1 American Journal of Physiology, Heart and Circulatory Physiology. 2009 Oct;297(4):H1535-43. Epub 2009 Aug 14 |
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Impaired Exercise Tolerance And Skeletal Muscle Myopathy In Sulfonylurea Receptor-2 Mutant Mice
Douglas A Stoller1, Peter Pytel1, Sophie Katz1, Judy U Earley1, Keith Collins1, Jamie Metcalfe1, Roberto M. Lang1, and Elizabeth M McNally1 American Journal of Physiology, Regulatory, Integrative and Comparative Physiology. 2009 Oct;297(4):R1144-53. Epub 2009 Aug 12 |
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Developmental Regulation Of Cardiovascular Function Is Dependent On Both Genotype And Environment
Brian S Knight, Nana Sunn, Craig E Pennell, S. Lee Adamson1, and Stephen J Lye2 American Journal of Physiology. Heart and Circulatory Physiology. 2009 Dec;297(6):H2234-41. Epub 2009 Sep 25 |
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iPS Programmed Without c-MYC Yield Proficient Cardiogenesis for Functional Heart Chimerism
Almudena Martinez-Fernandez ; Timothy J. Nelson ; Satsuki Yamada ; Santiago Reyes ; Alexey E. Alekseev ; Carmen Perez-Terzic ; Yasuhiro Ikeda ; and Andre Terzic Circulation Research. 2009 Sep 25;105(7):648-56. Epub 2009 Aug 20 |
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Absence of Akt1 Reduces Vascular Smooth Muscle Cell Migration and Survival and Induces Features of Plaque Vulnerability and Cardiac Dysfunction During Atherosclerosis
Carlos Fernández-Hernando ; Levente József ; Deborah Jenkins ; Annarita Di Lorenzo ; and William C. Sessa Arteriosclerosis, Thrombosis, and Vascular Biology. 2009 Dec;29(12):2033-40. Epub 2009 Sep 17 |
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A High Fat Diet Increases Adiposity but Maintains Mitochondrial Oxidative Enzymes without Affecting Development of Heart Failure with Pressure Overload
David J Chess1, Ramzi J Khairallah, Karen M O'Shea, Wenhong Xu, and William C. Stanley2 American Journal of Physiology. Heart and Circulatory Physiology. 2009 Nov;297(5):H1585-93. Epub 2009 Sep 18 |
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Induction of the CXC Chemokine Interferon-γ-Inducible Protein 10 Regulates the Reparative Response Following Myocardial Infarction
Marcin Bujak ; Marcin Dobaczewski ; Carlos Gonzalez-Quesada ; Ying Xia ; Thorsten Leucker ; Pawel Zymek ; Vikas Veeranna ; Andrew M. Tager ; Andrew D. Luster ; and Nikolaos G. Frangogiannis Circulation Research. 2009 Nov 6;105(10):973-83. Epub 2009 Sep 24 |
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Nitrite Therapy After Cardiac Arrest Reduces Reactive Oxygen Species Generation, Improves Cardiac and Neurological Function, and Enhances Survival via Reversible Inhibition of Mitochondrial Complex I
Cameron Dezfulian MD, Sruti Shiva PhD, Aleksey Alekseyenko BS, Akshay Pendyal BS, D. G. Beiser MD, Jeeva P. Munasinghe PhD, Stasia A. Anderson PhD, Christopher F. Chesley , T. L. Vanden Hoek MD, and Mark T. Gladwin MD Circulation. 2009 Sep 8;120(10):897-905. Epub 2009 Aug 24 |
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Novel Small Interfering RNA–Containing Solution Protecting Donor Organs in Heart Transplantation
Xiufen Zheng PhD, Dameng Lian MD, Arthur Wong BS, Michael Bygrave MS, Thomas E. Ichim PhD, Mahdieh Khoshniat PhD, Xusheng Zhang MD, Hongtao Sun MD, Tobias De Zordo MD, James C. Lacefield PhD, Bertha Garcia MD, Anthony M. Jevnikar MD, and Wei-Ping Min MD, PhD Circulation. 2009 Sep 22;120(12):1099-107, 1 p following 1107. Epub 2009 Sep 8 |
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Myeloid Differentiation Factor-88/Interleukin-1 Signaling Controls Cardiac Fibrosis and Heart Failure Progression in Inflammatory Dilated Cardiomyopathy
Przemyslaw Blyszczuk ; Gabriela Kania ; Thomas Dieterle ; Rene R. Marty ; Alan Valaperti ; Corinne Berthonneche ; Thierry Pedrazzini ; Christoph T. Berger ; Stephan Dirnhofer ; Christian M. Matter ; Josef M. Penninger ; Thomas F. Lüscher ; and Urs Eriksson Circulation Research. 2009 Oct 23;105(9):912-20. Epub 2009 Sep 17 |
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Cardiotoxic effects, or lack thereof, of anti-ErbB2 immunoagents
Gennaro Riccio, Giovanni Esposito, Emanuela Leoncini, Riccardo Contu, Gianluigi Condorelli, Massimo Chiariello, Paolo Laccetti, Silvana Hrelia, Giuseppe D'Alessio, and Claudia De Lorenzo The FASEB Journal. 2009 Sep;23(9):3171-8. Epub 2009 May 5 |
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Low-level laser irradiation inhibits abdominal aortic aneurysm progression in apolipoprotein E-deficient mice
Lilach Gavish1, Chen Rubinstein2, Atilla Bulut3, Yacov Berlatzky2, Ronen Beeri3, Dan Gilon3, Leah Gavish1, Mickey Harlev4, Petachia Reissman5 and S. David Gertz1 Cardiovascular Research. 2009 Sep 1;83(4):785-92. Epub 2009 May 14 |
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β-adrenoceptor stimulation of alveolar fluid clearance is increased in rats with heart failure
Michael B. Maron1, Daniel J Luther1, Charles F pilati1, Vahagn Ohanyan1, Tianbo Li1, Shyny Koshy1, Walter I Horne1, J. Gary Meszaros1, Jon M Walro1, and Hans G Folkesson1 American journal of physiology. Lung cellular and molecular physiology. 2009 Sep;297(3):L487-95. Epub 2009 Jul 10 |
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cGMP-hydrolytic activity and its inhibition by sildenafil in normal and failing human and mouse myocardium
Fabrice Vandeput 1, Judith Krall 1, Ramzi Ockaili 2, Fadi N Salloum 2, Vincent Florio 3, Jackie D. Corbin 4, Sharron H Francis 5, Rakesh C. Kukreja 2, Matthew A. Movsesian 1 The journal of pharmacology and experimental therapeutics. 2009 Sep;330(3):884-91. Epub 2009 Jun 22 |
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Chronic intermittent hypoxia increases left ventricular contractility in C57BL/6J mice
Jahan Naghshin1, Kenneth R. McGaffin1, William G. Witham1, Michael A. Mathier1, Lia C. Romano1, Steven H. Smith1, Andrzej M. Janczewski1, Jonathan A. Kirk1, Sanjeev G. Shroff1, and Christopher P. O'Donnell1 Journal of Applied Physiology. 2009 Sep;107(3):787-93. Epub 2009 Jul 9 |
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Chronic central versus systemic blockade of AT1 receptors and LV dysfunction in rats post myocardial infarction
Bing S Huang1, Monir Ahmad1, Junhui Tan1, and Frans HH Leenen1 American Journal of Physiology. Heart and Circulatory Physiology. 2009 Sep;297(3):H968-75. Epub 2009 Jul 17 |
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Calpain inhibition preserves myocardial structure and function following myocardial infarction
Santhosh K Mani, Sundaravadivel Balasubramanian, Juozas A Zavadzkas1, Laura B Jeffords1, William T. Rivers1, Michael R. Zile1, Rupak Mukherjee2, Francis G. Spinale1, and Dhandapani Kuppuswamy1 American Journal of Physiology, Heart and Circulatory Physiology. 2009 Nov;297(5):H1744-51. Epub 2009 Sep 4 |
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Effects of Fixed-Dose Isosorbide Dinitrate/Hydralazine on Diastolic Function and Exercise Capacity in Hypertension-Induced Diastolic Heart Failure
Richard M. Wilson; Deepa S. De Silva; Kaori Sato; Yasuhiro Izumiya; and Flora Sam Hypertension. 2009 Sep;54(3):583-90. Epub 2009 Jul 20 |
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Adiponectin deficiency: a model of pulmonary hypertension associated with pulmonary vascular disease
Ross S Summer1, Christopher A Fiack1, Yasumasa Ikeda1, Kaori Sato1, Daniel Dwyer1, Noriyuki Ouchi1, Alan Fine2, Harrison W. Farber2, and Kenneth Walsh2 American journal of physiology. Lung cellular and molecular physiology. 2009 Sep;297(3):L432-8. Epub 2009 Jun 26 |
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Parent-of-origin effects on cardiac response to pressure overload in mice
Cordelia J Barrick1, Anping Dong, Rebekah Waike1, Drew Corn1, Fanmuyi Yang, David W Threadgill, and Susan S Smyth2 American Journal of Physiology. Heart and Circulatory Physiology. 2009 Sep;297(3):H1003-9. Epub 2009 Jun 26 |
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Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease
Tatiana V. Tkatchenko1, Ricardo A. Moreno-Rodriguez2, Simon J. Conway3, Jeffery D Molkentin4, Roger R. Markwald2, and Andrei V. Tkatchenko1 Physiological genomics. 2009 Nov 6;39(3):160-8. Epub 2009 Sep 1 |
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Folate rescues lithium-, homocysteine- and Wnt3A-induced vertebrate cardiac anomalies
Mingda Han1, Maria C. Serrano1, Rosana Lastra-Vicente1, Pilar Brinez1, Ganesh Acharya2, James C. Huhta1, Ren Chen3 and Kersti K. Linask1 Disease models & mechanisms. 2009 Sep-Oct;2(9-10):467-78. Epub 2009 Jul 28 |
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Phosphodiesterase-5 Inhibitor, Tadalafil, Protects Against Myocardial Ischemia/Reperfusion Through Protein-Kinase G–Dependent Generation of Hydrogen Sulfide
Fadi N. Salloum, PhD; Vinh Q. Chau, BS; Nicholas N. Hoke, BS; Antonio Abbate, MD; Amit Varma, MD; Ramzi A. Ockaili, PhD; Stefano Toldo, MS; Rakesh C. Kukreja, PhD Circulation. 2009 Sep 15;120(11 Suppl):S31-6 |
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A Feedback Loop Involving the Phd3 Prolyl Hydroxylase Tunes the Mammalian Hypoxic Response In Vivo
Yoji Andrew Minamishima, Javid Moslehi, Robert F. Padera, Roderick T. Bronson, Ronglih Liao, and William G. Kaelin Jr. Molecular and cell biology. 2009 Nov;29(21):5729-41. Epub 2009 Aug 31 |
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Genetic Inhibition Of Calcineurin Induces Diastolic Dysfunction In Mice With Chronic Pressure Overload
Ricardo J. Gelpi1, Shumin Gao2, Peiyong Zhai3, Lin Yan2, Chull Hong, Lauren M.A. Danridge1, Hui Ge2, Yasuhiro Maejima1, Martin Donato4, Mitsuhiro Yokota5, Jeffery D Molkentin6, Dorothy E. Vatner2, Stephen F. Vatner2, and Junichi Sadoshima2 American Journal of Physiology, Heart and Circulatory Physiology. 2009 Nov;297(5):H1814-9. Epub 2009 Aug 28 |
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Impact of type 1 diabetes on cardiac fibroblast activation: enhanced cell cycle progression and reduced myofibroblast content in the diabetic myocardium
Patricia E Shamhart1, Daniel J Luther1, Ben R. Hodson1, John C. Koshy1, Vahagn Ohanyan1, and J. Gary Meszaros1 American Journal of Physiology. Endocrinology and Metabolism. 2009 Aug 25. [Epub ahead of print] |
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Metabolic Adaptations to Interrupted Glycosaminoglycan Recycling
Josh C. Woloszynek1,2, Atilla Kovacs1, Kevin K. Ohlemiller3, Marie Roberts1, and Mark S. Sands1,2 The Journal of Biological Chemistry. 2009 Oct 23;284(43):29684-91. Epub 2009 Aug 21 |
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Circulating Transforming Growth Factor-β in Marfan Syndrome
Peter Matt MD, Florian Schoenhoff MD, Jennifer Habashi MD, Tammy Holm MD, Christel Van Erp PhD, David Loch PhD, Olga D. Carlson PhD, Benjamin F. Griswold BSc, Qin Fu PhD, Julie De Backer MD, PhD, Bart Loeys MD, PhD, David L. Huso DVM, PhD, Nazli B. McDonnell MD, PhD, Jennifer E. Van Eyk PhD, Harry C. Dietz MD, the GenTAC Consortium Circulation. 2009 Aug 11;120(6):526-32. Epub 2009 Jul 27 |
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Repair of Acute Myocardial Infarction With Induced Pluripotent Stem Cells Induced by Human Stemness Factors
Timothy J. Nelson MD, PhD, Almudena Martinez-Fernandez PharmD, Satsuki Yamada MD, PhD, Carmen Perez-Terzic MD, PhD, Yasuhiro Ikeda DVM, PhD, and Andre Terzic MD, PhD Circulation. 2009 Aug 4;120(5):408-16. Epub 2009 Jul 20 |
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Myocyte necrosis underlies progressive myocardial dystrophy in mouse dsg2-related arrhythmogenic right ventricular cardiomyopathy
Kalliopi Pilichou1,3, Carol Ann Remme3, Cristina Basso1, Maria E. Campian3, Stefania Rizzo1, Phil Barnett3, Brendon P. Scicluna3, Barbara Bauce2, Maurice J.B. van den Hoff3, Jacques M.T. de Bakker3, Hanno L. Tan3, Marialuisa Valente1, Andrea Nava2, Arthur A.M. Wilde3, Antoon F.M. Moorman3, Gaetano Thiene1, and Connie R. Bezzina3 The Journal of Experimental Medicine. 2009 Aug 3;206(8):1787-802. Epub 2009 Jul 27 |
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Growth Arrest Specific Protein 6 Participates in DOCA-Induced Target-Organ Damage
Joon-Keun Park; Stefanie Theuer; Torsten Kirsch; Carsten Lindschau; Uwe Klinge; Arnd Heuser; Ralph Plehm; Mihai Todiras; Peter Carmeliet; Hermann Haller; Friedrich C. Luft; Dominik N. Muller; and Anette Fiebeler Hypertension. 2009 Aug;54(2):359-64. Epub 2009 Jun 29 |
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Long-Lived Ames Dwarf Mice Are Resistant to Chemical Stressors
Alex F. Bokov1,2, Merry L. Lindsey1,3, Christina Khodr4, Marian R. Sabia1,5 and Arlan Richardson1,2,5,6 The Journals of Gerontology Series A: Biological Sciences and Medical Sciences Advance Access. 2009 Aug;64(8):819-27. Epub 2009 May 4 |
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PARP inhibition delays transition of hypertensive cardiopathy to heart failure in spontaneously hypertensive rats.
Eva Bartha1,2, Izabella Solti2, Laszlo Kereskai3, Janos Lantos4, Eniko Plozer1, Klara Magyar1, Eszter Szabados1, Tamás Kálai5, Kálmán Hideg5, Robert Halmosi1, Balazs Sumegi2 and Kalman Toth1 Cardiovascular research. 2009 Aug 1;83(3):501-10. Epub 2009 May 14 |
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Adenosine Regulation of Microtubule Dynamics in Cardiac Hypertrophy
John Tollen Fassett1, Xin Xu1, Xinli Hu, Guangshuo Zhu, Joel P French2, Yingjie Chen1, and Robert J. Bache1 American Journal of Physiology, Heart and Circulatory Physiology. 2009 Aug;297(2):H523-32. Epub 2009 Jun 12 |
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Insulin-Stimulated Cardiac Glucose Oxidation Is Increased in High-Fat Diet–Induced Obese Mice Lacking Malonyl CoA Decarboxylase
John R. Ussher1, Timothy R. Koves2, Jagdip S. Jaswal1, Liyan Zhang1, Olga Ilkayeva2, Jason R.B. Dyck1, Deborah M. Muoio2 and Gary D. Lopaschuk1 Diabetes. 2009 Aug;58(8):1766-75. Epub 2009 May 28 |
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Cardiomyocyte-Specific Loss of Neurofibromin Promotes Cardiac Hypertrophy and Dysfunction
Junwang Xu ; Fraz A. Ismat ; Tao Wang ; Min Min Lu ; Nicole Antonucci ; and Jonathan A. Epstein Circulation Research. 2009 Jul 31;105(3):304-11. Epub 2009 Jul 2 |
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miR-23a functions downstream of NFATc3 to regulate cardiac hypertrophy
Zhiqiang Lin1, Iram Murtaza1, Kun Wang1, Jianqin Jiao1, Jie Gao1 and Pei-Feng Li1,2 Proceedings of the National Academy of Sciences of the United States of America. 2009 Jul 21;106(29):12103-8. Epub 2009 Jul 2 |
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In Vivo Metabolic Phenotyping of Myocardial Substrate Metabolism in Rodents. Differential Efficacy of Metformin and Rosiglitazone Monotherapy
Kooresh I. Shoghi, PhD; Brian N. Finck, PhD; Kenneth B. Schechtman, PhD; Terry Sharp; Pilar Herrero, MS; Robert J. Gropler, MD and Michael J. Welch, PhD Circulation: Cardiovascular Imaging. 2009 Sep;2(5):373-81. Epub 2009 Jul 21 |
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Control of heart rate by cAMP sensitivity of HCN channels
Jacqueline Alig1, Laurine Marger2, Pietro Mesirca2, Heimo Ehmke3, Matteo E. Mangoni2 and Dirk Isbrandt1 Proceedings of the National Academy of Sciences. 2009 Jul 21;106(29):12189-94. Epub 2009 Jul 1 |
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NF-κB activation is required for adaptive cardiac hypertrophy
Laura Zelarayan1,2, Anke Renger1,2, Claudia Noack1,2, Maria-Patapia Zafiriou1,2, Christina Gehrke1,2, Roel van der Nagel3, Rainer Dietz1,2, Leon de Windt3 and Martin W. Bergmann1,2 Cardiovascular Research. 2009 Dec 1;84(3):416-24. Epub 2009 Jul 20 |
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Endothelial deletion of hypoxia inducible factor-2alpha (HIF-2α) alters vascular function and tumor angiogenesis
Nicolas Skuli, Liping Liu, Anja Runge, Tao Wang, Lijun Yuan, Sunny Patel, Luisa Iruela-Arispe, M. Celeste Simon, and Brian Keith Blood. 2009 Jul 9;114(2):469-77. Epub 2009 May 13 |
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Cardiac 12/15 lipoxygenase–induced inflammation is involved in heart failure
Yosuke Kayama1,4, Tohru Minamino1,2, Haruhiro Toko1, Masaya Sakamoto3, Ippei Shimizu1, Hidehisa Takahashi1, Sho Okada1, Kaoru Tateno1, Junji Moriya1, Masataka Yokoyama1, Aika Nojima1, Michihiro Yoshimura4, Kensuke Egashira5, Hiroyuki Aburatani6, and Issei Komuro1 The journal of experimental medicine. 2009 Jul 6;206(7):1565-74. Epub 2009 Jun 22 |
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Cardiac Muscle Ring Finger-1 Increases Susceptibility to Heart Failure In Vivo
Monte S. Willis ; Jonathan C. Schisler ; Luge Li ; Jessica E. Rodríguez ; Eleanor G. Hilliard ; Peter C. Charles ; and Cam Patterson Circulation Research. 2009 Jul 2;105(1):80-8. Epub 2009 Jun 4 |
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IL-18 induction of Osteopontin mediates Cardiac Fibrosis and Diastolic Dysfunction in Mice
Qianli Yu1, Randy Vazquez1, Elham Vali Khojeini1, Chirag Patel1, Rajagopalan Venkataramani1, and Douglas F. Larson2 American Journal of Physiology, Heart and Circulatory Physiology. 2009 Jul;297(1):H76-85. Epub 2009 May 8 |
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Reduced EGFR causes abnormal valvular differentiation leading to calcific aortic stenosis and left ventricular hypertrophy in C57BL/6J but not 129S1/SvImJ mice
Cordelia J. Barrick1, Reade B Roberts1, Mauricio Rojas1, Nalini M. Rajamannan2, Carolyn B Suitt1, Kevin D. O'Brien3, Susan S Smyth4, and David W Threadgill5 American Journal of Physiology, Heart and Circulatory Physiology. 2009 Jul;297(1):H65-75. Epub 2009 May 15 |
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Developmental programming resulting from maternal obesity in mice: effects on myocardial ischaemia–reperfusion injury
John W. Calvert1, David J. Lefer1, Susheel Gundewar1, Lucilla Poston2 and William A. Coetzee3 Experimental Physiology. 2009 Jul;94(7):805-14. Epub 2009 Apr 24 |
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Overexpression of CYP2J2 Provides Protection against Doxorubicin Induced Cardiotoxicity
Yungfang Zhang1, Haitham El-Sikhry1, Ketul Chaudhary1, Sri Nagarjun Batchu1, Anooshirvan Shayeganpour1, Taibeh Orujy Jukar1, J. Alyce Bradbury, Joan P. Graves2, Laura M DeGraff, Page H Myers3, Douglas Clay Rouse3, Julie Foley2, Abraham Nyska4, Darryl C. Zeldin5, and John M Seubert1 American Journal of Physiology, Heart and Circulatory Physiology. 2009 Jul;297(1):H37-46. Epub 2009 May 8 |
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A new mouse model of metabolic syndrome and associated complications
Yun Wang, Yue Zheng, Patsy M Nishina and Jürgen K Naggert Journal of Endocrinology. 2009 Jul;202(1):17-28. Epub 2009 Apr 27 |
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Cardiac-Restricted Overexpression of Membrane Type-1 Matrix Metalloproteinase in Mice: Effects on Myocardial Remodeling With Aging
Francis G. Spinale, MD, PhD; G. Patricia Escobar, DVM; Rupak Mukherjee, PhD; Juozas A. Zavadzkas, MD; Stuart M. Saunders, MD; Laura B. Jeffords, BS; Allyson M. Leone, BS; Christy Beck, BS; Shenikqua Bouges, BS and Robert E. Stroud, MS Circulation: Heart Failure. 2009 Jul;2(4):351-60. Epub 2009 May 8 |
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Doppler flow velocity waveforms in the embryonic chicken heart at developmental stages corresponding to 5-8 weeks of human gestation
A. M. Oosterbaan 1, N. T. C. Ursem 1, P. C. Struijk 1, J. G. Bosch 2, A. F. W. van der Steen 2, E. A. P. Steegers 1 Ultrasound in Obstetrics & Gynecology. 2009 Jun;33(6):638-44 |
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PDK1 coordinates survival pathways and ß-adrenergic response in the heart
Kaoru Ito1, Hiroshi Akazawa1, Masaji Tamagawa2, Kensuke Furukawa3, Wataru Ogawa3, Noritaka Yasuda1, Yoko Kudo1, Chien-hui Liao1, Rie Yamamoto1, Toshiaki Sato2, Jeffery D. Molkentin4, Masato Kasuga3, Tetsuo Noda5, Haruaki Nakaya2 and Issei Komuro1 Proceedings of the National Academy of Sciences. 2009 May 26;106(21):8689-94. Epub 2009 May 8 |
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Hypoxic Preconditioning Enhances the Benefit of Cardiac Progenitor Cell Therapy for Treatment of Myocardial Infarction by Inducing CXCR4 Expression
Yao Liang Tang ; Wuqiang Zhu ; Min Cheng ; Lijuan Chen ; John Zhang ; Tao Sun ; Raj Kishore ; M. Ian Phillips ; Douglas W. Losordo ; and Gangjian Qin Circulation Research. 2009 May 22;104(10):1209-16. Epub 2009 Apr 30 |
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Reduced Vessel Elasticity Alters Cardiovascular Structure and Function in Newborn Mice
Jessica E. Wagenseil; Chris H. Ciliberto ; Russell H. Knutsen ; Marilyn A. Levy ; Attila Kovacs ; and Robert P. Mecham Circulation Research. 2009 May 22;104(10):1217-24. Epub 2009 Apr 16 |
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IL-6 Loss Causes Ventricular Dysfunction, Fibrosis, Reduced Capillary Density and Dramatically Alters the Cell Populations of the Developing and Adult Heart
Indroneal Banerjee, John W. Fuseler, Arti R. Intwala, and Troy A Baudino American Journal of Physiology: Heart and Circulatory Physiology. 2009 May;296(5):H1694-704. Epub 2009 Feb 20 |
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Systemic Injection of Planktonic Forms of Mammalian-derived Nanoparticles Alters Arterial Response to Injury in Rabbits
Maria K Schwartz1, John C. Lieske1, Larry W. Hunter1, and Virginia M. Miller1 American Journal of Physiology. Heart and Circulatory Physiology. 2009 May;296(5):H1434-41. Epub 2009 Mar 13 |
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Atherosclerotic Plaque Disruption Induced by Stress and Lipopolysaccharide in Apolipoprotein E Knockout Mice
Mei Ni1, Yan Wang2, Mei Zhang3, Peng-Fei Zhang, Shi-Fang Ding, Chun Xi Liu4, Xiao Ling Liu, Yu Xia Zhao2, and Yun Zhang5 American Journal of Physiology. Heart and Circulatory Physiology. 2009 May;296(5):H1598-606. Epub 2009 Mar 13 |
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Single histidine button in cardiac troponin I sustains heart performance in response to severe hypercapnic respiratory acidosis in vivo
Nathan J. Palpant, Louis G. D’Alecy, and Joseph M. Metzger The FASEB Journal 2009 May;23(5):1529-40. Epub 2009 Jan 13 |
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A novel 3-dimensional micro-ultrasound approach to automated measurement of carotid arterial plaque volume as a biomarker for experimental atherosclerosis
Matthew Walker III, Barry R. Campbell, Karim Azer, Christopher Tong, Kaijie Fang, Jacquelynn J. Cook, Michael J. Forrest, Kimberly Kempadoo, Samuel D.Wright, Jeffrey S. Saltzman, Euan MacIntyre, Richard Hargreaves Atherosclerosis 2009 May;204(1):55-65. Epub 2008 Sep 19 |
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Functional Significance and Morphological Characterization of Starvation-Induced Autophagy in the Adult Heart
Hiromitsu Kanamori12, Genzou Takemura1, Rumi Maruyama1, Kazuko Goto1, Akiko Tsujimoto1, Atsushi Ogino1, Longhu Li1, Itta Kawamura1, Toshiaki Takeyama1, Tomonori Kawaguchi1, Kenshi Nagashima1, Takako Fujiwara3, Hisayoshi Fujiwara1, Mitsuru Seishima2 and Shinya Minatoguchi1 The American Journal of Pathology. 2009 May;174(5):1705-14. Epub 2009 Mar 26 |
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The Role of NADPH Oxidase in Chronic Intermittent Hypoxia-induced Pulmonary Hypertension in Mice
Rachel E. Nisbet, Anitra S. Graves, Dean J. Kleinhenz, Heidi L. Rupnow, Alana L. Reed, Tai-Hwang M. Fan, Patrick Oliver Mitchell, Roy L. Sutliff, and C. Michael Hart American Journal of Respiratory Cell and Molecular Biology. 2009 May;40(5):601-9. Epub 2008 Oct 23 |
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Apelin Prevents Aortic Aneurysm Formation by Inhibiting Macrophage Inflammation
Nicholas J Leeper1, Maureen M Tedesco1, Yoko Kojima1, Geoffrey M Schultz1, Ramendra K. Kundu1, Euan A Ashley1, Philip S. Tsao2, Ronald L Dalman, and Thomas Quertermous1 American Journal of Physiology. Heart and Circulatory Physiology. 2009 May;296(5):H1329-35. Epub 2009 Mar 20 |
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Thyroid analogue 3,5-diiodothyropropionic acid (DITPA) promotes healthy vasculature in adult myocardium independent of thyroid effects on cardiac function
Yingheng Liu1, Dajun Wang1, Rebecca A Redetzke1, Benjamin A Sherer1, and Anthony Martin Gerdes1 American Journal of Physiology. Heart and Circulatory Physiology. 2009 May;296(5):H1551-7. Epub 2009 Mar 13 |
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A Novel Role for Tumor Necrosis Factor–Like Weak Inducer of Apoptosis (TWEAK) in the Development of Cardiac Dysfunction and Failure
Mohit Jain MD, PhD, Aniela Jakubowski MS, Lei Cui MD, Jianru Shi PhD, Lihe Su PhD, Michael Bauer MD, Jian Guan MD, Chee Chew Lim PhD, Yoshiro Naito MD, PhD, Jeffrey S. Thompson BS, Flora Sam MD, Christine Ambrose PhD, Michael Parr PhD, Thomas Crowell BS, John M. Lincecum PhD, Monica Z. Wang BS, Yen-Ming Hsu PhD, Timothy S. Zheng PhD, Jennifer S. Michaelson PhD, Ronglih Liao PhD*, and Linda C. Burkly PhD Circulation. 2009 Apr 21;119(15):2058-68. Epub 2009 Apr 6 |
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Endogenous S-nitrosothiols protect against myocardial injury
Brian Limaa,1, Gregory K. W. Lamb,1, Liang Xieb, Diana L. Diesenb, Nestor Villamizara, Jeffrey Nienabera, Emily Messinaa, Dawn Bowlesa, Christopher D. Kontosb, Joshua M. Harec, Jonathan S. Stamlerb and Howard A. Rockmanb,2 Proceedings of the National Academy of Sciences of the United States of America. 2009 Apr 14;106(15):6297-302. Epub 2009 Mar 26 |
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Hypoxia induces dilated cardiomyopathy in the chick embryo: mechanism, intervention, and long-term consequences
Andrei Tintu1,2, Ellen Rouwet3, Stefan Verlohren1,4, Joep Brinkmann1, Shakil Ahmad5, Fatima Crispi6, Marc van Bilsen7, Peter Carmeliet8, Anne Cathrine Staff9, Marc Tjwa10, Irene Cetin11, Eduard Gratacos6, Edgar Hernandez-Andrade6, Leo Hofstra12, Michael Jacobs2, Wouter H. Lamers13, Ingo Morano14, Erdal Safak15, Asif Ahmed5, Ferdinand le Noble1 PloS One. 2009;4(4):e5155. Epub 2009 Apr 9 |
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The magnitude and temporal dependence of apoptosis early after myocardial ischemia with or without reperfusion
Christopher J. French, Jeffrey L. Spees, A. K. M. Tarikuz Zaman, Douglas J. Taatjes, and Burton E. Sobel FASEB Journal. 2009 Apr;23(4):1177-85. Epub 2008 Dec 18 |
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Echocardiographic assessment of global left ventricular function in mice
Jörg Stypmann 1 2 3 , Markus A Engelen 1 4, Clemens Troatz 3 5, Markus Rothenburger 6, Lars Eckardt 1 and Klaus Tiemann 3 5 Laboratory Animals. 2009 Apr;43(2):127-37. Epub 2009 Feb 23 |
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Diastolic dysfunction in familial hypertrophic cardiomyopathy transgenic model mice
Theodore P. Abraham, Michelle Jones, Katarzyna Kazmierczak, Hsin-Yueh Liang, Aurelio C. Pinheiro, Cory S. Wagg, Gary D. Lopaschuk and Danuta Szczesna-Cordary Cardiovascular Research. 2009 Apr 1;82(1):84-92. Epub 2009 Jan 15 |
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Muscle Ring Finger-1 (MuRF1) Mediates Cardiac Atrophy in vivo
Monte S Willis, Mauricio Rojas, Luge Li, Craig H Selzman, Ru-Hang Tang, William E. Stansfield, Jessica E Rodriguez, David Glass, and Cam Patterson American Journal of Physiology: Heart and Circulatory Physiology. 2009 Apr;296(4):H997-H1006. Epub 2009 Jan 23 |
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Effect of in vitro maturation of mouse oocytes on the health and lifespan of adult offspring
J.J. Eppig, M.J. O’Brien, K. Wigglesworth, A. Nicholson, W. Zhang, and B.A. King Human Reproduction. 2009 Apr;24(4):922-8. Epub 2009 Jan 16 |
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microRNA-1 negatively regulates expression of the hypertrophy-associated genes calmodulin and Mef2a
Sadakatsu Ikeda, Aibin He, Sek Won Kong, Jun Lu, Rafael Bejar, Natalya Bodyak, Kyu-Ho Lee, Qing Ma, Peter M. Kang, Todd R. Golub, and William T. Pu Molecular and Cell Biology 2009 Apr;29(8):2193-204. Epub 2009 Feb 2 |
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Reversal of Cardiac Myocyte Dysfunction as a Unique Mechanism of Rescue by P2X4 Receptors in Cardiomyopathy
Jian-Bing Shen, Robin H. Shutt, Mariela Agosto, Achilles J. Pappano, and Bruce T. Liang American Journal of Physiology : Heart and Circulatory Physiology 2009 Apr;296(4):H1089-95. Epub 2009 Feb 6 |
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Resveratrol Prevents the Prohypertrophic Effects of Oxidative Stress on LKB1
Vernon W. Dolinsky PhD, Anita Y.M. Chan BSc, Isabelle Robillard Frayne MSc, Peter E. Light PhD, Christine Des Rosiers PhD, and Jason R.B. Dyck PhD Circulation. 2009 Mar 31;119(12):1643-52. Epub 2009 Mar 16 |
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Bosentan Enhances Viral Load via Endothelin-1 Receptor Type-A-Mediated p38 Mitogen-Activated Protein Kinase Activation While Improving Cardiac Function During Coxsackievirus-Induced Myocarditis
David Marchant, Ying Dou, Honglin Luo, Farshid S. Garmaroudi, John E. McDonough, Xiaoning Si, Elizabeth Walker, Zongshu Luo, Anders Arner, Richard G. Hegele, Ismail Laher, and Bruce M. McManus Circulation Research. 2009 Mar 27;104(6):813-21. Epub 2009 Feb 12 |
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CXCL10 Inhibits Viral Replication Through Recruitment of Natural Killer Cells in Coxsackievirus B3-Induced Myocarditis
Ji Yuan; Zhen Liu; Travis Lim; Huifang Zhang; Jianqing He; Elizabeth Walker; Courtney Shier; Yinjing Wang; Yue Su; Alhousseynou Sall; Bruce McManus; and Decheng Yang Circulation Research. 2009 Mar 13;104(5):628-38. Epub 2009 Jan 22 |
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Early-Life Sodium Exposure Unmasks Susceptibility to Stroke in Hyperlipidemic, Hypertensive Heterozygous Tg25 Rats Transgenic for Human Cholesteryl Ester Transfer Protein
Julius L. Decano MD, Jason C. Viereck MD, PhD, Ann C. McKee MD, James A. Hamilton PhD, Nelson Ruiz-Opazo PhD, and Victoria L.M. Herrera MD Circulation. 2009 Mar 24;119(11):1501-9. Epub 2009 Mar 9 |
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Pheochromocytoma-Induced Cardiomyopathy is Modulated by the Synergistic Effects of Cell-Secreted Factors
Hector R. Mobine, PhD; Aaron B. Baker, PhD; Libin Wang, MD, PhD; Hiroko Wakimoto, MD, PhD; Kurt C. Jacobsen, MS; Christine E. Seidman, MD; J.G. Seidman, PhD and Elazer R. Edelman, MD, PhD Circulation: Heart Failure. 2009 Mar;2(2):121-8. Epub 2009 Feb 10 |
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Effects of hypoxia-induced intrauterine growth restriction on cardiopulmonary structure and function during adulthood
Christian F. Rueda-Clausen, Jude S. Morton and Sandra T. Davidge Cardiovascular Research. 2009 Mar 1;81(4):713-22. Epub 2008 Dec 16 |
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A profibrotic effect of plasminogen activator inhibitor type-1 (PAI-1) in the heart
AKM Tarikuz Zaman, Christopher J. French, David J. Schneider, and Burton E. Sobel Experimental biology and medicine (Maywood, N.J.). 2009 Mar; 234(3):246-54. Epub 2009 Jan 14 |
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Central infusion of aldosterone synthase inhibitor attenuates left ventricular dysfunction and remodelling in rats after myocardial infarction
Bing S. Huang, Roselyn A. White, Monir Ahmad, Junhui Tan, Arco Y. Jeng, and Frans H.H. Leenen Cardiovascular Research. 2009 Feb 15;81(3):574-81. Epub 2008 Aug 8 |
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Activation of AMP-Activated Protein Kinase by Metformin Improves Left Ventricular Function and Survival in Heart Failure
Susheel Gundewar, John W. Calvert, Saurabh Jha, Iris Toedt-Pingel, Sang Yong Ji, Denise Nunez, Arun Ramachandran, Mauricio Anaya-Cisneros, Rong Tian, David J. Lefer Circulation Research. 2009 Feb 13;104(3):403-11. Epub 2008 Dec 18 |
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Fish oil, but not flaxseed oil, decreases inflammation and prevents pressure overload-induced cardiac dysfunction
Monika K. Duda, Karen M. O’Shea, Anselm Tintinu, Wenhong Xu, Ramzi J. Khairallah, Brian R. Barrows, David J. Chess, Agnes M. Azimzadeh, William S. Harris, Victor G. Sharov, Hani N. Sabbah, and William C. Stanley Cardiovascular Research. 2009 Feb 1;81(2):319-27. Epub 2008 Nov 17 |
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Effects of Cyclooxygenase-2 Gene Inactivation on Cardiac Autonomic and Left Ventricular Function in Experimental Diabetes
Aaron P. Kellogg, Kimber Converso, Tim Wiggin, Martin Stevens and Rodica Pop-Busui American journal of physiology. Heart and circulatory physiology. 2009 Feb;296(2):H453-61. Epub 2008 Dec 5 |
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IL-10 Inhibits Inflammation and Attenuates Left Ventricular Remodeling After Myocardial Infarction via Activation of STAT3 and Suppression of HuR
Prasanna Krishnamurthy, Johnson Rajasingh, Erin Lambers, Gangjian Qin, Douglas W. Losordo, Raj Kishore Circulation Research. 2009 Jan 30;104(2):e9-18. Epub 2008 Dec 18 |
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Disruption of Striated Preferentially Expressed Gene Locus Leads to Dilated Cardiomyopathy in Mice
Xiaoli Liu, MD, PhD; Tripurasundari Ramjiganesh, PhD; Yen-Hsu Chen, MD, PhD; Su Wol Chung, PhD; Sean R. Hall, PhD; Scott L. Schissel, MD, PhD; Robert F. Padera, Jr, MD, PhD; Ronglih Liao, PhD; Kate G. Ackerman, MD; Jan Kajstura, PhD; Annarosa Leri, MD; Piero Anversa, MD; Shaw-Fang Yet, PhD; Matthew D. Layne, PhD; Mark A. Perrella, MD Circulation. 2009 Jan 20;119(2):261-8. Epub 2008 Dec 31 |
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Combined therapy with cardioprotective cytokine administration and antiapoptotic gene transfer in postinfarction heart failure
Hideshi Okada, Genzou Takemura, Ken-ichiro Kosai, Akiko Tsujimoto, Masayasu Esaki, Tomoyuki Takahashi, Satoshi Nagano, Hiromitsu Kanamori, Shusaku Miyata, Yiwen Li, Takamasa Ohno, Rumi Maruyama, Atsushi Ogino, Longhu Li, Munehiro Nakagawa, Kenshi Nagashima, Takako Fujiwara, Hisayoshi Fujiwara, and Shinya Minatoguchi American Journal of Physiology: Heart and Circulatory Physiology. 2009 Mar;296(3):H616-26. Epub 2009 Jan 16 |
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Inhibition of extracellular signal-regulated kinase signaling to prevent cardiomyopathy caused by mutation in the gene encoding A-type lamins
Antoine Muchir, Jian Shan, Gisèle Bonne, Stephan E. Lehnart and Howard J. Worman Human Molecular Genetics. 2009 Jan 15;18(2):241-7 |
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Acute Doxorubicin Cardiotoxicity Is Associated With p53-Induced Inhibition of the Mammalian Target of Rapamycin Pathway
Wuqiang Zhu, MD, PhD; Mark H. Soonpaa, PhD; Hanying Chen, MD; Weihua Shen, PhD; R. Mark Payne, MD; Edward A. Liechty, MD; Randall L. Caldwell, MD; Weinian Shou, PhD; Loren J. Field, PhD Circulation 2009 Jan 6;119(1):99-106. Epub 2008 Dec 22 |
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Smad7 Is Required for the Development and Function of the Heart
Qian Chen, Hanying Chen, Dawei Zheng, Chenzhong Kuang, Hong Fangi, Bingyu Zou, Wuqiang Zhu, Guixue Bu, Ting Jin, Zhenzhen Wang, Xin Zhang, Ju Chen, Loren J. Field, Michael Rubart, Weinian Shou, and Yan Chen The Journal of Biological Chemistry. 2009 Jan 2;284(1):292-300. Epub 2008 Oct 24 |
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IFATS Collection: Human Adipose Tissue-Derived Stem Cells Induce Angiogenesis and Nerve Sprouting Following Myocardial Infarction, in Conjunction with Potent Preservation of Cardiac Function
Liying Cai, Brian H. Johnstone, Todd G. Cook, Jian Tan, Michael C. Fishbein, Peng-Sheng Chen, Keith L. March Stem Cells. 2009 Jan; Vol. 27 No. 1, pp. 230 -237; Epub 2008 Sep 4 |
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Scavenging Superoxide Selectively in Mouse Forebrain is Associated with Improved Cardiac Function and Survival Following Myocardial Infarction
Timothy E. Lindley, David W. Infanger, Mark Rishniw, Yi Zhou, Marc F. Doobay, Ram V. Sharma, and Robin L. Davisson American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 2009 Jan;296(1):R1-8. Epub 2008 Oct 29 |
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Regression of pressure-induced left ventricular hypertrophy is characterized by a distinct gene expression profile
William E. Stansfield, MD, Peter C. Charles, PhD, Ru-hang Tang, PhD, Mauricio Rojas, MD, Rajendra Bhati, MD, Nancy C. Moss, MD, Cam Patterson, MD, Craig H. Selzman, MD The Journal of Thoracic and Cardiovascular Surgery. 2009 Jan;137(1):232-8, 238e1-8 |
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Embryonic caffeine exposure induces adverse effects in adulthood
Christopher C. Wendler, Melissa Busovsky-McNeal, Satish Ghatpande, April Kalinowski, Kerry S. Russell, and Scott A. Rivkees The FASEB Journal. 2009 Apr;23(4):1272-8. Epub 2008 Dec 16 |
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Unchanged {beta}-Adrenergic Stimulation of Cardiac L-type Calcium Channels in Cav1.2 Phosphorylation Site S1928A Mutant Mice
Toni Lemke, Andrea Welling, Carl Johannes Christel, Anne Blaich, Dominik Bernhard, Peter Lenhardt, Franz Hofmann, and Sven Moosmang The Journal of Biological Chemistry. 2008 Dec 12;283(50):34738-44. Epub 2008 Sep 30 |
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Angiotensin II Type 2 Receptor Stimulation: A Novel Option of Therapeutic Interference With the Renin-Angiotensin System in Myocardial Infarction?
Elena Kaschina, MD; Aleksandra Grzesiak, MD; Jun Li, MD; Anna Foryst-Ludwig, PhD; Melanie Timm, MTA; Franziska Rompe, MSc; Manuela Sommerfeld, MTA; U. Rudolf Kemnitz, MTA; Caterina Curato, MSc; Pawel Namsolleck, MSc; Carsten Tschöpe, MD, PhD; Anders Hallberg, PhD; Mathias Alterman, PhD; Thomas Hucko, MD; Ingo Paetsch, MD, PhD; Thore Dietrich, PhD; Bernhard Schnackenburg, PhD; Kristof Graf, MD, PhD; Björn Dahlöf, MD, PhD; Ulrich Kintscher, MD, PhD; Thomas Unger, MD, PhD; U. Muscha Steckelings, MD Circulation. 2008 Dec 9;118(24):2523-32. Epub 2008 Nov 24 |
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Homozygous Missense N629D hERG (KCNH2) Potassium Channel Mutation Causes Developmental Defects in the Right Ventricle and Its Outflow Tract and Embryonic Lethality
Guo Qi Teng, Xian Zhao, James P. Lees-Miller, F. Russell Quinn, Pin Li, Derrick E. Rancourt, Barry London, James C. Cross, Henry J. Duff Circulation Research. 2008 Dec 5;103(12):1483-91. Epub 2008 Oct 23 |
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{alpha}B-Crystallin Suppresses Pressure Overload Cardiac Hypertrophy
Asangi R.K. Kumarapeli, Huabo Su, Wei Huang, Mingxin Tang, Hanqiao Zheng, Kathleen M. Horak, Manxiang Li, Xuejun Wang Circulation Research. 2008 Dec 5;103(12):1473-82. Epub 2008 Oct 30 |
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Phosphatase inhibitor-1-deficient mice are protected from catecholamine-induced arrhythmias and myocardial hypertrophy
El-Armouche A, Wittköpper K, Degenhardt F, Weinberger F, Didié M, Melnychenko I, Grimm M, Peeck M, Zimmermann WH, Unsöld B, Hasenfuss G, Dobrev D, Eschenhagen T. Cardiovascular Research. 2008 Dec 1;80(3):396-406. |
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The antioxidant tempol attenuates pressure overload-induced cardiac hypertrophy and contractile dysfunction in mice fed a high-fructose diet
David J. Chess, Wenhong Xu, Ramzi Khairallah, Karen M. O’Shea, Willem J. Kop, Agnes M. Azimzadeh, and William C. Stanley Am J Physiol Heart Circ Physiol. 2008 Dec;295(6):H2223-30. Epub 2008 Oct 17 |
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Heme Oxygenase-1 Regulates Cardiac Mitochondrial Biogenesis via Nrf2-Mediated Transcriptional Control of Nuclear Respiratory Factor-1
Claude A. Piantadosi, Martha Sue Carraway, Abdelwahid Babiker, Hagir B. Suliman Circular Research. 2008 Nov 21;103(11):1191-3 |
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Essential Role of Developmentally Activated Hypoxia-Inducible Factor 1{alpha} for Cardiac Morphogenesis and Function
Jaya Krishnan, Preeti Ahuja, Sereina Bodenmann, Don Knapik, Evelyne Perriard, Wilhelm Krek, Jean-Claude Perriard. Circulation Research. 2008 Nov 7;103(10):1139-46. Epub 2008 Oct 10 |
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Effects of rosuvastatin on cardiovascular morphology and function in an ApoE-knockout mouse model of atherosclerosis
Grönros J, Wikström J, Brandt-Eliasson U, Forsberg GB, Behrendt M, Hansson GI, Gan LM. American Journal of Physiology, Heart and Circulatory Physiology. 2008 Nov;295(5):H2046-53. |
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Single histidine-substituted cardiac troponin I confers protection from age-related systolic and diastolic dysfunction
Nathan J. Palpant, Sharlene M. Day, Todd J. Herron, Kimber L. Converso and Joseph M. Metzger Cardiovascular Research. 2008 Nov 1;80(2):209-18. |
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Acceleration of crossbridge kinetics by protein kinase A phosphorylation of cardiac myosin binding protein C modulates cardiac function
Tong CW, Stelzer JE, Greaser ML, Powers PA, Moss RL. Circulation Research. 2008 Oct 24;103(9):974-82. Epub 2008 Sep 18 |
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Overexpression of Vascular Endothelial Growth Factor-B in Mouse Heart Alters Cardiac Lipid Metabolism and Induces Myocardial Hypertrophy
Terhi Karpanen, Maija Bry, Hanna M. Ollila, Tuulikki Seppänen-Laakso, Erkki Liimatta, Hanna Leskinen, Riikka Kivelä, Teemu Helkamaa, Mari Merentie, Michael Jeltsch, Karri Paavonen, Leif C. Andersson, Eero Mervaala, Ilmo E. Hassinen, Seppo Ylä-Herttuala, Matej Oreši?, Kari Alitalo Circulation Research. 2008 Oct 24;103(9):1018-26. Epub 2008 Aug 28 |
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Adenosine A3 receptor deficiency exerts unanticipated protective effects on the pressure-overloaded left ventricle
Zhongbing Lu, John Fassett, Xin Xu, Xinli Hu, Guangshuo Zhu, Joel French, Ping Zhang, Jurgen Schnermann, Robert J. Bache, Yingjie Chen Circulation Research. 2008 Oct 21;118(17):1713-21. |
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Echocardiography in translational research: of mice and men
Scherrer-Crosbie M, Thibault HB Journal of the American Society of Echocardiography. 2008 Oct;21(10):1083-92. |
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Cardiac-restricted overexpression of extracellular matrix metalloproteinase inducer causes myocardial remodeling and dysfunction in aging mice
Juozas A. Zavadzkas, Rebecca A. Plyler, Shenikqua Bouges, Christine N. Koval, William T. Rivers, Christy U. Beck, Eileen I. Chang, Robert E. Stroud, Rupak Mukherjee, and Francis G. Spinale American Journal of Physiology. Heart and Circulatory Physiology. 2008 Oct;295(4):H1394-402. Epub 2008 Aug 8 |
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Role of the Multidomain Protein Spinophilin in Blood Pressure and Cardiac Function Regulation
Andrey C. da Costa-Goncalves, Jens Tank, Ralph Plehm, Andre Diedrich, Mihail Todiras, Maik Gollasch, Arnd Heuser, Maren Wellner, Michael Bader, Jens Jordan, Friedrich C. Luft, Volkmar Gross Hypertension. 2008 Oct;52(4):702-7 |
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Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer
Bo Wu, Hong M. Moulton, Patrick L. Iversen, Jiangang Jiang, Juan Li, Jianbin Li, Christopher F. Spurney, Arpana Sali, Alfredo D. Guerron, Kanneboyina Nagaraju, Timothy Doran, Peijuan Lu, Xiao Xiao, and Qi Long Lu PNAS. 2008 Sept 30; vol. 105 no. 39 14814-14819 |
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Cardiac Metabolic Compensation to Hypertension Requires Lipoprotein Lipase
Yamashita H, Bharadwaj KG, Ikeda S, Park TS, Goldberg IJ. American Journal of Physiology, Endocrinology and Metabolism. 2008 Sep;295(3):E705-13. Epub 2008 Jul 22 |
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Role of P2X Purinergic Receptors in the Rescue of Ischemic Heart Failure
Sonin D, Zhou SY, Cronin C, Sonina T, Wu J, Jacobson KA, Pappano A, Liang BT. American Journal of Physiology, Heart and Circulatory Physiology. 2008 Sep;295(3):H1191-H1197. Epub 2008 Jul 18 |
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ECHO parameters of diastolic dysfunction
A Schumacher, EV Khojeini, DF Larson Perfusion. 2008 Sep; Vol.23, No.5, 291-296 |
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Effect of clenbuterol administration on the healthy murine heart
D Moore, M Anderson, DF Larson Perfusion. 2008 Sep; Vol. 23, No. 5, 297-302 |
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Prevention and Treatment of Functional and Structural Radiation Injury in the Rat Heart by Pentoxifylline and Alpha-Tocopherol
Marjan Boerma, Ph.D.1, Kerrey A. Roberto, B.S.1, Martin Hauer-Jensen, M.D., Ph.D.2 International Journal of Radiation Oncology, Biology, Physics. 2008 Sep 1;72(1):170-7. Epub 2008 Jul 14 |
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Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes
Jeffrey S. Martini, Philip Raake, Leif E. Vinge, Brent R. DeGeorge, Jr., J. Kurt Chuprun, David M. Harris, Erhe Gao, Andrea D. Eckhart, Julie A. Pitcher, and Walter J. Koch Proceedings of the National Academy of Sciences of the United States of America. 2008 Aug 26;105(34):12457-62. Epub 2008 Aug 18 |
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High-resolution magnetic resonance histology of the embryonic and neonatal mouse: A 4D atlas and morphologic database
Alexandra E. Petiet, Matthew H. Kaufman, Matthew M. Goddeeris, Jeffrey Brandenburg, Susan A. Elmore, and G. Allan Johnson Proceedings of the National Academy of Sciences of the United States of America. 2008 Aug 26;105(34):12331-6 |
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Blunted hypoxic pulmonary vasoconstriction in experimental neonatal chronic lung disease
Rey-Parra GJ, Archer SL, Bland RD, Albertine KH, Carlton DP, Cho SC, Kirby B, Haromy A, Eaton F, Wu X, Thébaud B. American Journal of Respiratory and Critical Care Medicine. 2008 Aug 15;178(4):399-406. |
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Cardiac ErbB-1/ErbB-2 mutant expression in young adult mice leads to cardiac dysfunction
Rajagopalan V, Zucker IH, Jones JA, Carlson M, Ma YJ American Journal of Physiology, Heart and Circulatory Physiology. 2008 Aug;295(2):H543-54. |
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Substrate Uptake and Metabolism are Preserved in Hypertrophic Caveolin-3 Knockout Hearts
Augustus AS, Buchanan J, Addya S, Rengo G, Pestell RG, Fortina P, Koch WJ, Bensadoun A, Abel ED, Lisanti MP. American Journal of Physiology, Heart and Circulatory Physiology. 2008 Aug;295(2):H657-66. Epub 2008 Jun 13 |
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Time Course of Alterations in Myocardial Glucose Utilization in the Zucker Diabetic Fatty Rat with Correlation to Gene Expression of Glucose Transporters: A Small-Animal PET Investigation
Shoghi KI, Gropler RJ, Sharp T, Herrero P, Fettig N, Su Y, Mitra MS, Kovacs A, Finck BN, Welch MJ Journal of Nuclear Medicine. 2008 Aug;49(8):1320-7. |
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Transcriptional coactivators PGC-1{alpha} and PGC-1{beta} control overlapping programs required for perinatal maturation of the heart
Ling Lai, Teresa C. Leone, Christoph Zechner, Paul J. Schaeffer, Sean M. Kelly, Daniel P. Flanagan, Denis M. Medeiros, Attila Kovacs, and Daniel P. Kelly Genes & Development. 2008 Jul 15;22(14):1948-61 |
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The effect of daily administration of IL-18 on cardiac structure and function
A Platis, Q Yu, D Moore, EV Khojeini, P Tsau, DF Larson Perfusion. 2008 Jul; Vol. 23, No. 4, 237-242 |
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Comparison of isoproterenol and dobutamine in the induction of cardiac hypertrophy and fibrosis
M Anderson, D Moore, DF Larson Perfusion. 2008 Jul; Vol. 23, No. 4, 231-235 |
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Intracellular calcium leak due to FKBP12.6 deficiency in mice facilitates the inducibility of atrial fibrillation
Subeena Sood, PhD1, Mihail G. Chelu, MD, PhD1, Ralph J. van Oort, PhD1, Darlene Skapura, BSc1, Marco Santonastasi, MEng1, Dobromir Dobrev, MD2, Xander H.T. Wehrens, MD, PhD, FESC1,3 Heart Rhythm. 2008 Jul;5(7):1047-1054 |
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Bacillus Calmette-Guerin and TLR4 agonist prevent cardiovascular hypertrophy and fibrosis by regulating immune microenvironment
Liu YY, Cai WF, Yang HZ, Cui B, Chen ZR, Liu HZ, Yan J, Jin W, Yan HM, Xin BM, Yuan B, Hua F, Hu ZW Journal of Immunology. 2008 Jun 1;180(11):7349-57. |
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A novel mouse model of X-linked cardiac hypertrophy
Leatherbury L, Yu Q, Chatterjee B, Walker DL, Yu Z, Tian X, Lo CW American Journal of Physiology, Heart and Circulatory Physiology. 2008 Jun;294(6):H2701-11. |
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Impaired relaxation is the main manifestation in transgenic mice expressing a restrictive cardiomyopathy mutation, R193H, in cardiac TnI
Jianfeng Du, Jing Liu, Han-Zhong Feng, M. M. Hossain, Nariman Gobara, Chi Zhang, Yuejin Li, Pierre-Yves Jean-Charles, Jian-Ping Jin, and Xu-Pei Huang American Journal of Physiology, Heart and Circulatory Physiology. 2008 April 11; 294: H2604-H2613 |
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Mouse heart valve structure and function: echocardiographic and morphometric analyses from the fetus through the aged adult
Robert B. Hinton, Jr., Christina M. Alfieri, Sandra A. Witt, Betty J. Glascock, Philip R. Khoury, D. Woodrow Benson, and Katherine E. Yutzey American Journal of Physiology, Heart and Circulatory Physiology. 2008 April 4;294: H2480-H2488 |
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Relationship between retention of a vascular endothelial growth factor receptor 2 (VEGFR2)-targeted ultrasonographic contrast agent and the level of VEGFR2 expression in an in vivo breast cancer model
Lee DJ, Lyshchik A, Huamani J, Hallahan DE, Fleischer AC Journal of Ultrasound in Medicine. 2008 Jun;27(6):855-66. |
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Cardiomyocyte expression of a polyglutamine preamyloid oligomer causes heart failure
Pattison JS, Sanbe A, Maloyan A, Osinska H, Klevitsky R, Robbins J. Circulation. 2008 May 27;117(21):2743-51. |
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S100A8 and S100A9 Mediate Endotoxin-Induced Cardiomyocyte Dysfunction via the Receptor for Advanced Glycation End Products
John H. Boyd, Bernard Kan, Haley Roberts, Yingjin Wang, Keith R. Walley Circulation Research. 2008;102:1239-1246. |
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Anakinra, a Recombinant Human Interleukin-1 Receptor Antagonist, Inhibits Apoptosis in Experimental Acute Myocardial Infarction
Antonio Abbate MD*, Fadi N. Salloum PhD, Elena Vecile PhD, Anindita Das PhD, Nicholas N. Hoke BS, Stefania Straino BS, Giuseppe G.L. Biondi-Zoccai MD, Jon-Erik Houser MD, Ian Z. Qureshi PhD, Evan D. Ownby MD, Edoardo Gustini PhD, Luigi M. Biasucci MD, Anna Severino PhD, Maurizio C. Capogrossi MD, George W. Vetrovec MD, Filippo Crea MD, Alfonso Baldi MD, Rakesh C. Kukreja PhD, and Aldo Dobrina MD Circulation. 2008 May 20;117(20):2670-83. |
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Cardiac restricted overexpression of kinase-dead mammalian target of rapamycin (mTOR) mutant impairs the mTOR-mediated signaling and cardiac function
Shen WH, Chen Z, Shi S, Chen H, Zhu W, Penner A, Bu G, Li W, Boyle DW, Rubart M, Field LJ, Abraham R, Liechty EA, Shou W. The Journal of Biological Chemistry. 2008 May 16;283(20):13842-9. |
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Interleukin-13 protects against experimental autoimmune myocarditis by regulating macrophage differentiation
Daniela Cihakova, Jobert G. Barin, Marina Afanasyeva, Miho Kimura, DeLisa Fairweather, Michael Berg, Monica V. Talor, G. Christian Baldeviano, Sylvia Frisancho, Kathleen Gabrielson||, Djahida Bedja| and Noel R. Rose American Journal of Pathology. 2008 May;172(5):1195-208. Epub 2008 Apr 10 |
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Adrenergic regulation of cardiac contractility does not involve phosphorylation of the cardiac ryanodine receptor at serine 2808
Scott M. MacDonnell, Gerardo García-Rivas, Joseph A. Scherman, Hajime Kubo, Xiongwen Chen, Héctor Valdivia, Steven R. Houser Circulation Research. 2008 Apr 25 (recent version);102:e65-e72. Epub 2008 Apr 3 |
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Imaging of VEGF receptor in a rat myocardial infarction model using PET
Rodriguez-Porcel M, Cai W, Gheysens O, Willmann JK, Chen K, Wang H, Chen IY, He L, Wu JC, Li ZB, Mohamedali KA, Kim S, Rosenblum MG, Chen X, Gambhir SS Journal of Nuclear Medicine. 2008 Apr;49(4):667-73. |
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Rgs5 targeting leads to chronic low blood pressure and a lean body habitus
Hyeseon Cho,Chung Park, Il-Young Hwang,Sang-Bae Han, Dan Schimel, Daryl Despres, and John H. Kehrl Molecular and Cellular Biology. 2008 April;28(8): 2590-2597. |
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Ablation of matrix metalloproteinase-9 increases severity of viral myocarditis in mice
Caroline Cheung, David Marchant, Elizabeth K.-Y. Walker, Zongshu Luo, Jingchun Zhang, Bobby Yanagawa, Maziar Rahmani, Jennifer Cox, Christopher Overall, Robert M. Senior, Honglin Luo, Bruce M. McManus Circulation. 2008 Mar 25;117(12):1574-82. Epub 2008 Mar 10 |
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Deletion of Ptpn11 (Shp2) in cardiomyocytes causes dilated cardiomyopathy via effects on the extracellular signal-regulated kinase/mitogen-activated protein kinase and RhoA signaling pathways
Kontaridis MI, Yang W, Bence KK, Cullen D, Wang B, Bodyak N, Ke Q, Hinek A, Kang PM, Liao R, Neel BG Circulation. 2008 Mar 18;117(11):1423-35. |
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Role of sulfonylurea receptor type 1 subunits of ATP-sensitive potassium channels in myocardial ischemia/reperfusion injury
John W. Elrod, Maddison Harrell, Thomas P. Flagg, Susheel Gundewar, Mark A. Magnuson, Colin G. Nichols, William A. Coetzee, David J. Lefer Circulation. 2008 Mar 18;117(11):1405-13. Epub 2008 Mar 3 |
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Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure
Minamishima YA, Moslehi J, Bardeesy N, Cullen D, Bronson RT, Kaelin WG Jr. Blood. 2008 Mar 15;111(6):3236-44. |
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Acute Metformin Therapy Confers Cardioprotection Against Myocardial Infarction Via AMPK-eNOS-Mediated Signaling
John W. Calvert, Susheel Gundewar, Saurabh Jha, James J.M. Greer, William H. Bestermann, Rong Tian, and David J. Lefer Diabetes. 2008 Mar;57(3):696-705. Epub 2007 Dec 14 |
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Innovations in imaging for chronic total occlusions: a glimpse into the future of angiography's blind-spot
Brian K. Courtney, Nigel R. Munce, Kevan J. Anderson, Amandeep S. Thind, General Leung, Perry E. Radau, F. Stuart Foster, I. Alex Vitkin, Robert S. Schwartz, Alexander J. Dick, Graham A. Wright and Bradley H. Strauss European Heart Journal. 2008 Mar;29(5):583-93 |
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Sildenafil (Viagra) Attenuates Ischemic Cardiomyopathy and Improves Left Ventricular Function in Mice
Salloum FN, Abbate A, Das A, Houser JE, Mudrick CA, Qureshi IZ, Hoke NN, Roy SK, Brown WR, Prabhakar S, Kukreja RC. American Journal of Physiological Health. 2008 Mar;294(3):H1398-406. Epub 2008 Jan 25 |
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The butyrylcholinesterase knockout mouse as a model for human butyrylcholinesterase deficiency
Li B, Duysen EG, Carlson M, Lockridge O The Journal of Pharmacology and Experimental Therapeutics. 2008 Mar;324(3):1146-54. |
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Serum thyroid hormone levels may not accurately reflect thyroid tissue levels and cardiac function in mild hypothyroidism
Yingheng Liu, Rebecca A. Redetzke, Suleman Said, James V. Pottala, Gabriella Morreale de Escobar, and A. Martin Gerdes American Journal of Physiology, Heart and Circulatory Physiology. 2008 Feb 29; 294: H2137-H2143. |
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Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure
Jian-Fu Chen, Elizabeth P. Murchison, Ruhang Tang, Thomas E. Callis, Mariko Tatsuguchi, Zhongliang Deng, Mauricio Rojas , Scott M. Hammond, Michael D. Schneider, Craig H. Selzman, Gerhard Meissner, Cam Patterson , Gregory J. Hannon, and Da-Zhi Wang Proceedings of the National Academy of Sciences. 2008 February 12;105(6): 2111-2116. |
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In Vivo Measurement of Flow-Mediated Vasodilation in Living Rats using High-Resolution Ultrasound
Christian Heiss1, Richard E. Sievers2, Nicolas Amabile1, Tony Y Momma3, Qiumei Chen2, Shobha Natarajan1, Yerem Yeghiazarians1, and Matthew L. Springer1* Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H1086-93. Epub 2007 Nov 30 |
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Proteasome inhibition promotes regression of left ventricular hypertrophy
William E. Stansfield1, Ruhang Tang1, Nancy C Moss1, Albert S Baldwin2, Monte S Willis3, and Craig H Selzman1 American Journal of Physiology, Heart and Circulatory Physiology. 2008 Feb;294(2):H645-50. Epub 2007 Nov 21 |
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Treatment with an adenoviral vector encoding hepatocyte growth factor mitigates established cardiac dysfunction in doxorubicin-induced cardiomyopathy
Masayasu Esaki, Genzou Takemura, Ken-ichiro Kosai, Tomoyuki Takahashi, Shusaku Miyata, Longhu Li, Kazuko Goto, Rumi Maruyama, Hideshi Okada, Hiromitsu Kanamori, Atsushi Ogino, Hiroaki Ushikoshi, Shinya Minatoguchi, Takako Fujiwara, and Hisayoshi Fujiwara American Journal of Physiology, Heart and Circulatory Physiology. 2008 Feb;294(2):H1048-57. Epub 2007 Dec 14 |
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Extracellular superoxide dismutase deficiency exacerbates pressure overload-induced left ventricular hypertrophy and dysfunction
Lu Z, Xu X, Hu X, Zhu G, Zhang P, van Deel ED, French JP, Fassett JT, Oury TD, Bache RJ, Chen Y Hypertension. 2008 Jan;51(1):19-25. |
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Co-expression of skeletal and cardiac troponin T decreases mouse cardiac function
Qi-Quan Huang, Hanzhong Feng, Jing Liu, Jianfeng Du, Linda B. Stull, Christine Moravec, Xupei Huang, and J.-P. Jin American Journal of Physiology, Cell Physiology. 2008 Jan;294(1):C213-22. Epub 2007 Oct 24 |
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Secoisolariciresinol diglucoside induces neovascularization-mediated cardioprotection against ischemia–reperfusion injury in hypercholesterolemic myocardium
Suresh Varma Penumathsa, Srikanth Koneru, Lijun Zhan, Saji John, Venogopal P. Menon , Kailash Prasad, Nilanjana Maulik J Mol Cell Cardiol.2008 Jan;44(1):170-9. Epub 2007 Oct 4 |
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Introduction to rodent cardiac imaging
Johnson K. Institute for Laboratory Animal Research Journal. 2008 Jan;49(1):27-34. |
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Leptin signalling reduces the severity of cardiac dysfunction and remodelling after chronic ischaemic injury
McGaffin KR, Sun CK, Rager JJ, Romano LC, Zou B, Mathier MA, O'Doherty RM, McTiernan CF, O'Donnell CP Cardiovascular Research. 2008 Jan;77(1):54-63. |
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Direct effects of volatile anesthetics on cardiac functiona
S Gentry-Smetana, D Redford, D Moore and DF Larson Perfusion. 2008 Jan;23(1):43-7 |
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Synergetic Antioxidant and Vasodilatory Action of Carbon Monoxide in Angiotensin II–Induced Cardiac Hypertrophy
Atsushi Kobayashi; Kazunobu Ishikawa; Hayato Matsumoto; Satoshi Kimura; Yoshiyuki Kamiyama; Yukio Maruyama Hypertension. 2007 Dec;50(6):1040-8. Epub 2007 Oct 8 |
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CD36 Expression Contributes to Age-Induced Cardiomyopathy in Mice
Koonen DP, Febbraio M, Bonnet S, Nagendran J, Young ME, Michelakis ED, Dyck JR. Circulation. 2007 Nov 6;116(19):2139-47. Epub 2007 Oct 22. |
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Vascular smooth muscle Gq signaling is involved in high blood pressure in both induced renal and genetic vascular smooth muscle-derived models of hypertension
David M. Harris, Heather I. Cohn, Stéphanie Pesant, Rui-Hai Zhou, and Andrea D. Eckhart American journal of physiology. Heart and circulatory physiology. 2007 Nov;293(5):H3072-9. Epub 2007 Sep 14 |
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Decreased L-Type Ca2+ Current in Cardiac Myocytes of Type 1 Diabetic Akita Mice Due to Reduced Phosphatidylinositol 3-Kinase Signaling
Zhongju Lu1, Ya-Ping Jiang2, Xin-Hua Xu3, Lisa M. Ballou2, Ira S. Cohen1, and Richard Z. Lin1,2,4 Diabetes. 2007 Nov;56(11):2780-9. Epub 2007 Jul 31 |
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Left Ventricular Functional Assessment in Mice: Feasibility of High Spatial and Temporal Resolution ECG-gated Blood Pool SPECT
Bennett B. Chin, MD, Scott D. Metzler, PhD, Anthony Lemaire, MD, Antonio Curcio, MD, Sreekanth Vemulapalli, BS, Kim L. Greer, CNMT, Neil A. Petry, MS, Timothy G. Turkington, PhD, R. Edward Coleman, MD, Howard Rockman, MD, and Ronald J. Jaszczak, PhD Radiology. 2007 Nov;245(2):440-8 |
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Improved Myocardial Motion Tracking in Mouse Echocardiography using Large-Diameter Microbubbles
Yinbo Li, Christopher D. Garson, Yaqin Xu, Brent A. French and John A. Hossack Ultrasonics Symposium, 2007. IEEE. 2007 Oct 28-31; PP. 892 - 895 |
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Comparative Study of High-resolution Microimaging with 30-MHz Scanner for Evaluating Cardiac Function in Mice
Okajima K, Abe Y, Fujimoto K, Fujikura K, Girard EE, Asai T, Kwon SH, Jin Z, Nakamura Y, Yoshiyama M, Homma S. J Am Soc Echocardiogr. 2007 Oct;20(10):1203-10. Epub 2007 Jun 25 |
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Dystrophin-deficiency increases the susceptibility to doxorubicin-induced cardiotoxicity
Deng S, Kulle B, Hosseini M, Schlüter G, Hasenfuss G, Wojnowski L, Schmidt A. Eur J Heart Fail.2007 Oct; Vol 9, Issue 10, Pages 986-994; Epub 2007 Sep 19 |
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Cytoprotective effects of N,N,N-trimethylsphingosine during ischemia- reperfusion injury are lost in the setting of obesity and diabetes
Susheel Gundewar, John W. Calvert, John W. Elrod, and David J. Lefer Am J Physiol Heart Circ Physiol.2007 Oct;293(4):H2462-71. Epub 2007 Jul 13 |
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Characterization of a Model to Independently Study Regression of Ventricular Hypertrophy
William E. Stansfield, Mauricio Rojas, Drew Corn, Monte Willis, Cam Patterson, Susan S. Smyth and Craig H. Selzman Journal of Surgical Research,2007 Oct;142(2):387-93. Epub 2007 Jun 14 |
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Amlodipine inhibits granulation tissue cell apoptosis through reducing calcineurin activity to attenuate postinfarction cardiac remodeling
Atsushi Ogino,1 Genzou Takemura,1 Hiromitsu Kanamori,1 Hideshi Okada,1 Rumi Maruyama,1 Shusaku Miyata,1 Masayasu Esaki,1 Munehiro Nakagawa,1 Takuma Aoyama,1 Hiroaki Ushikoshi,1 Masanori Kawasaki,1 Shinya Minatoguchi,1 Takako Fujiwara,2 and Hisayoshi Fujiwara1 American journal of physiology. Heart and circulatory physiology. 2007 Oct;293(4):H2271-80. Epub 2007 Jul 20 |
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Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function
John W. Elrod*, John W. Calvert*, Joanna Morrison , Jeannette E. Doeller , David W. Kraus , Ling Tao , Xiangying Jiao , Rosario Scalia¶, Levente Kiss||, Csaba Szabo||, Hideo Kimura**, Chi-Wing Chow, and David J. Lefer PNAS,2007 Sept 25; Vol.104, No.39, Pg 15560-15565 |
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Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection
Noma T, Lemaire A, Naga Prasad SV, Barki-Harrington L, Tilley DG, Chen J, Le Corvoisier P, Violin JD, Wei H, Lefkowitz RJ, Rockman HA. J Clin Invest. 2007 Sep 4;117(9):2445-58 |
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Cardiac Specific Haploin sufficiency of ß-Catenin Attenuates Cardiac Hypertrophy But Enhances Fetal Gene Expression in Response to Aortic Constriction
Jiaxiang Qu1, Jibin Zhou1, Xian Ping Yi1,2, Baojun Dong1, Hanqiao Zheng1, Lisa M. Miller1, Xuejun Wang1, Michael D. Schneider4, Faqian Li1 Journal of Molecular and Cellular Cardiology. 2007 Sept; 43(3): 319-326; Epub 2007 Jun 21 |
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Differential Roles of Cardiac Myosin-Binding Protein C and Cardiac Troponin I in the Myofibrillar Force Responses to Protein Kinase A Phosphorylation
Julian E. Stelzer, Jitandrakumar R. Patel, Jeffery W. Walker, Richard L. Moss Circulation research. 2007 Aug 31;101(5):503-11. Epub 2007 Jul 19 |
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A PRKAG2 mutation causes biphasic changes in myocardial AMPK activity and does not protect against ischemia
Sanjay K. Banerjee, Ravi Ramani, Samir Saba, Jennifer Rager, Rong Tian, Michael A. Mathier and Ferhaan Ahmad Biochemical and Biophysical Research Communications, 2007 Aug 24;360(2):381-7. Epub 2007 Jun 19 |
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Gi{alpha}1-Mediated Cardiac Electrophysiological Remodeling and Arrhythmia in Hypertrophic Cardiomyopathy
Hongmei Ruan, Scherise Mitchell, Monika Vainoriene, Qing Lou, Lai-Hua Xie; Shuxun Ren, Joshua I. Goldhaber, Yibin Wang Circulation. 2007 Aug 7;116 (6): 596-605; Epub 2007 July 23 |
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Deleterious effects of lack of cardiac PAI-1 after coronary occlusion in mice and their pathophysiologic determinants
Zaman AK, Fujii S, Schneider DJ, Taatjes DJ, Lijnen HR, Sobel BE. Histochem Cell Biol. 2007 Aug;128(2):135-45. Epub 2007 Jun 19 |
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Myocardial Elastography At Both High Temporal And Spatial Resolution For The Detection Of Infarcts
Jianwen Luo,* Kana Fujikura,* Shunichi Homma,† and Elisa E. Konofagou*‡ Ultrasound in Med.2007 Aug;33(8):1206-23. Epub 2007 Jun 13 |
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Cardiac repolarization is prolonged in CD4C/HIV transgenic mice
Judith Brouillettea,b, Scott A. Grandya,b, Paul Jolicoeurc, Céline Fiseta,b J Mol Cell Cardiol.2007 Aug;43(2):159-67. Epub 2007 May 18 |
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Interferon-{gamma} Induces Chronic Active Myocarditis and Cardiomyopathy in Transgenic Mice
Kurt Reifenberg*@, Hans-Anton Lehr , Michael Torzewski , Gisela Steige*, Elena Wiese*, Ines Küpper*, Christoph Becker , Sibylle Ott¶, Petra Nusser¶, Ken-Ichi Yamamura||, Gerd Rechtsteinerd**, Tobias Warger**, Nadine Graf , Hartmut Kleinert , Albrecht Schmidt , Burkert Pieske , Philip Wenzel , Thomas Münzel , and Jürgen Löhler¶¶ American Journal of Pathology. 2007 Aug 1; 171(2): 463-472 |
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Progressive troponin I loss impairs cardiac relaxation and causes heart failure in mice
Jing Liu,1 Jianfeng Du,1 Chi Zhang,1 Jeffery W. Walker,2 and Xupei Huang1 American journal of physiology. Heart and circulatory physiology. 2007 Aug;293(2):H1273-81. Epub 2007 May 25 |
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Gene Therapy to Inhibit the Calcium Channel {beta} Subunit: Physiological Consequences and Pathophysiological Effects in Models of Cardiac Hypertrophy
Eugenio Cingolani, Genaro A. Ramirez Correa, Eddy Kizana, Mitsushige Murata, Hee Cheol Cho, Eduardo Marbán Circulation Research. 2007 Jul 20;101(2):166-75. Epub 2007 Jun 7 |
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ECG-Gated, Mechanical And Electromechanical Wave Imaging Of Cardiovascular Tissues In Vivo
MATHIEU PERNOT,* KANA FUJIKURA,* SIMON D. FUNG-KEE-FUNG,* and ELISA E. KONOFAGOU*† Ultrasound in Med. & Biol.,2007 Jul;33(7):1075-85. Epub 2007 May 15 |
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Proteasome Inhibition Attenuates Infarct Size and Preserves Cardiac Function in a Murine Model of Myocardial Ischemia-Reperfusion Injury
William E. Stansfield, Nancy C. Moss, Monte S. Willis, Ruhang Tang and Craig H. Selzman The Annals of Thoracic Surgery,2007 Jul;84(1):120-125 |
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Phenylbutyrate, a histone deacetylase inhibitor, protects against Adriamycin-induced cardiac injury
Chotiros Daosukhoab, Yumin Chena, Teresa Noela, Pradoldej Sompola, Ramaneeya Nithipongvanitchc, Joyce M. Veleza, Terry D. Oberleyc and Daret K. St. Claira Free Radical Biology and Medicine,2007 Jun 15;42(12):1818-25. Epub 2007 Mar 12 |
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Quantification and mri validation of regional contractile dysfunction in mice post myocardial infarction using high resolution ultrasound
Li Y, Garson CD, Xu Y, Beyers RJ, Epstein FH, French BA, Hossack JA. Ultrasound Med Biol. 2007 Jun;33(6):894-904. Epub 2007 Apr 16 |
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Morphological and functional evaluation of murine heterotopic cardiac grafts using ultrasound biomicroscopy
Zhou YQ, Bishay R, Feintuch A, Tao K, Golding F, Zhu W, West LJ, Henkelman RM. Ultrasound Med Biol. 2007 Jun;33(6):870-9. Epub 2007 Apr 16 |
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Finite element modeling of blood flow-induced mechanical forces in the outflow tract of chick embryonic hearts
Aiping Liu, Sandra Rugonyi, Jeffrey O. Pentecost, Kent L. Thornburg Computers and Structures. 2007 Jun-Jul; 85(11-14):727–738 |
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{beta}-Catenin Downregulation Is Required for Adaptive Cardiac Remodeling
Anthony Baurand, Laura Zelarayan, Russell Betney, Christina Gehrke, Sandra Dunger, Claudia Noack, Andreas Busjahn, Joerg Huelsken, Makoto Mark Taketo, Walter Birchmeier, Rainer Dietz, Martin W. Bergmann Circulation Research,2007 May 11;100(9):1353-62. Epub 2007 Apr 5 |
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Pulse doppler and M-mode to assess viability of cardiac allografts using heterotopic femoral heart transplantation in rats
Gordon CR, Lefebvre DR, Matthews MS, Strande LF, Marra SW, Guglielmi M, Skaf J, Hollenberg SM, Hewitt CW. Microsurgery. 2007 May 9; 27(4):240-4 |
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Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca release channel
Naohiro Yamaguchi1, Nobuyuki Takahashi2, Le Xu1, Oliver Smithies2 and Gerhard Meissner1 J. Clin. Invest. 2007 May;117(5):1344-53. Epub 2007 Apr 12 |
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Cardiac response to pressure overload in 129S1/SvImJ and C57BL/6J mice: temporal- and background-dependent development of concentric left ventricular hypertrophy
Barrick CJ, Rojas M, Schoonhoven R, Smyth SS, Threadgill DW. Am J Physiol Heart Circ Physiol. 2007 May;292(5):H2119-30. Epub 2006 Dec 15. |
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Inhibition of Fas-associated apoptosis in granulation tissue cells accompanies attenuation of postinfarction left ventricular remodeling by olmesartan
Hiromitsu Kanamori, Genzou Takemura, Yiwen Li, Hideshi Okada, Rumi Maruyama, Takuma Aoyama, Shusaku Miyata, Masayasu Esaki, Atsushi Ogino, Munehiro Nakagawa, Hiroaki Ushikoshi, Masanori Kawasaki, Shinya Minatoguchi, and Hisayoshi Fujiwara American journal of physiology. Heart and circulatory physiology. 2007 May;292(5):H2184-94. Epub 2007 Jan 5 |
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Kruppel-like factor 15 is a regulator of cardiomyocyte hypertrophy
Sudeshna Fisch*, Susan Gray*, Stephane Heymans†, Saptarsi M. Haldar‡, Baiqiu Wang‡, Otmar Pfister, Lei Cui, Ajay Kumar*, Zhiyong Lin‡, Sucharita Sen-Banerjee*, Hiranmoy Das‡, Christine A. Petersen, Ulrike Mende*, Barbara A. Burleigh, Yan Zhu_, Yigal Pinto†, Ronglih Liao, and Mukesh K. Jain‡* PNAS,2007 Apr 24;104(17):7074-9. Epub 2007 Apr 16 |
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Dysregulation of Cardiogenesis, Cardiac Conduction, and Cell Cycle in Mice Lacking miRNA-1-2
Yong Zhao, Joshua F. Ransom, Ankang Li, Vasanth Vedantham, Morgan von Drehl, Alecia N. Muth, Takatoshi Tsuchihashi, Michael T. McManus, Robert J. Schwartz and Deepak Srivastava Cell,2007 Apr 20;129(2):303-17. Epub 2007 Mar 29 |
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Automated contour tracking for myocardial elastography in vivo
Jianwen Luo; Fujikura, K.; Homma, S.; Konofagou, E.E. 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro. 2007 Apr 12-15: PP 952-5 |
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The host immune response is essential for the beneficial effect of adult stem cells after myocardial ischemia
Tolar J, Wang X, Braunlin E, McElmurry RT, Nakamura Y, Bell S, Xia L, Zhang J, Hu Q, Panoskaltsis-Mortari A, Zhang J, Blazar BR. Exp Hematol. 2007 Apr; Vol 35, Issue 4, PP 682-690 |
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Myostatin does not regulate cardiac hypertrophy or fibrosis
Cohn RD, Liang HY, Shetty R, Abraham T, Wagner KR. Neuromuscul Disord. 2007 Apr;17(4):290-6. Epub 2007 Mar 2 |
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Myocardial infarct size measurement in the mouse chronic infarction model: comparison of area- and length-based approaches
Junya Takagawa1, Yan Zhang1, Maelene L. Wong1, Richard E. Sievers1, Neel K. Kapasi1, Yan Wang2, Yerem Yeghiazarians1, Randall J. Lee1, William Grossman1, and Matthew L. Springer1 J Appl Physiol2007 Mar 8; 102: 2104-2111 |
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Muscle Ring Finger 1, but not Muscle Ring Finger 2, Regulates Cardiac Hypertrophy In Vivo
Monte S. Willis, Christopher Ike, Luge Li, Da-Zhi Wang, David J. Glass, Cam Patterson. Circulation Research. 2007 Mar 2; In Press; Epub 2007 Feb 1 |
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Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity
Trivedi CM, Luo Y, Yin Z, Zhang M, Zhu W, Wang T, Floss T, Goettlicher M, Noppinger PR, Wurst W, Ferrari VA, Abrams CS, Gruber PJ, Epstein JA. Nat Med. 2007 Mar;13(3):324-31. Epub 2007 Feb 18. |
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Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy
Michael H. Radke*, Jun Peng , Yiming Wu , Mark McNabb , O. Lynne Nelson , Henk Granzier , and Michael Gotthardt PNAS,2007 Feb 27;104(9):3444-9. Epub 2007 Feb 20 |
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Heat Shock Protein 90 and ErbB2 in the Cardiac Response to Doxorubicin Injury
Kathleen Gabrielson, Djahida Bedja, Scott Pin, Allison Tsao, Lucio Gama, Bibo Yuan and Nicole Muratore Cancer Research. 2007 Feb 15;67(4):1436-41 |
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Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens
Smith RR, Barile L, Cho HC, Leppo MK, Hare JM, Messina E, Giacomello A, Abraham MR, Marban E. Circulation. 2007 Feb 20;115(7):896-908. Epub 2007 Feb 5 |
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Validation of the wall motion score and myocardial performance indexes as novel techniques to assess cardiac function in mice after myocardial infarction
Zhang Y, Takagawa J, Sievers R, Khan MF, Viswanathan M, Springer ML, Foster E, Yeghiazarians Y. Am J Physiol Heart Circ Physiol. 2007 Feb;292(2):H1187-92. Epub 2006 Oct 6 |
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Hemodynamics in the Mouse Aortic Arch as Assessed by MRI, Ultrasound and, Numerical Modeling
Feintuch A, Ruengsakulrach P, Lin A, Zhang J, Zhou Y, Bishop J, Davidson L, Courtman D, Foster FS, Steinman D, Henkelman RM, Ethier CR. Am J Physiol Heart Circ Physiol. 2007 Feb;292(2):H884-92. Epub 2006 Sep 29 |
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High-Resolution Myocardial Perfusion Imaging in Mice with High-Frequency Echocardiographic Detection of a Depot Contrast Agent
Beat A. Kaufmann, MDab, Miles Lankford, BSb, Carolyn Z. Behm, MDb, Brent A. French, PhDb, Alexander L. Klibanov, PhDb, Yaqin Xu, MD, PhDb, Jonathan R. Lindner. J of Am Society of Echo. 2007 Feb; Vol 20, Issue 2, PP. 136-143 |
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Secoisolariciresinol Diglucoside: Relevance to Angiogenesis and Cardioprotection against Ischemia-Reperfusion Injury
Suresh Varma Penumathsa, Srikanth Koneru, Mahesh Thirunavukkarasu, Lijun Zhan, Kailash Prasad, and Nilanjana Maulik The Journal of Pharmacology and experimental therapeutics. 2007 Feb;320(2):951-9. Epub 2006 Nov 28 |
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Doppler ultrasound in mice
Stypmann J. Echocardiography. 2007 Jan;24(1):97-112. |
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Upregulation of {gamma}-catenin compensates for the loss of beta-catenin in adult cardiomyocytes
Jibin Zhou, Jiaxiang Qu, Xian Ping Yi, Kelly Graber, Lu Huber, Xuejun Wang, A. Martin Gerdes, and Faqian Li Am J Physiol Heart Circ Physiol. 2007 Jan;292(1):H270-6. Epub 2006 Aug 25. |
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A point mutation (R192H) in the C-terminus of human cardiac troponin I causes diastolic dysfunction in transgenic mice
Du J, Zhang C, Liu J, Sidky C, Huang XP. Arch Biochem Biophys. 2006 Dec 15;456(2):143-50. Epub 2006 Sep 5 |
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[High-resolution ultrasound imaging of the mouse]
G Renault, P Bonnin, C Marchiol-Fournigault, JM Gregoire, S Serrière, B Richard, D Fradelizi Éditions Françaises de Radiologie. 2006 Dec; Vol 87 - N° 12-C2 |
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Toll-like receptor stimulation in cardiomyoctes decreases contractility and initiates an NF-{kappa}B dependent inflammatory response
John H. Boyd, Sumeet Mathur, Yingjin Wang, Ryon M. Bateman, Keith R. Walley Cardiovascular Research. 2006 Dec 1;72(3):384-93. Epub 2006 Sep 23 |
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Techniques et applications de l’échographie haute résolution non invasive (Techniques and applications of non-invasive high-resolution ultrasound imaging)
J-M Grégoire, S Serrière, G Georgesco, F Jamet, A Bleuzen, F Ossant, F Levassort, F Tranquart, F Patat Éditions Françaises de Radiologie, 2006 Dec; Vol 87 - N° 12-C2 |
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Integrin-linked kinase expression is elevated in human cardiac hypertrophy and induces hypertrophy in transgenic mice
Lu H, Fedak PW, Dai X, Du C, Zhou YQ, Henkelman M, Mongroo PS, Lau A, Yamabi H, Hinek A, Husain M, Hannigan G, Coles JG. Circulation. 2006 Nov 21;114(21):2271-9. Epub 2006 Nov 6. |
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Improved Cardiac Function in Infarcted Mice After Treatment With Pluripotent Embryonic Stem Cells
TIMOTHY J. NELSON, ZHI-DONG GE, JORDAN VAN ORMAN, MATTHEW BARRON,DIANE RUDY-REIL, TIMOTHYA. HACKER, RAVI MISRA, STEPHEN A. DUNCAN, JOHN A. AUCHAMPACH, AND JOHN W. LOUGH The Anatomical Record Part A, Discoveries in molecular, cellular, and evolutionary biology. 2006 Nov;288(11):1216-24 |
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Competitive displacement of phosphoinositide 3-kinase from beta-adrenergic receptor kinase-1 improves postinfarction adverse myocardial remodeling
Curcio A, Noma T, Naga Prasad SV, Wolf MJ, Lemaire A, Perrino C, Mao L, Rockman HA. Am J Physiol Heart Circ Physiol. 2006 Oct;291(4):H1754-60. Epub 2006 May 12 |
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Overexpression of Bone Morphogenetic Protein 10 in Myocardium Disrupts Cardiac Postnatal Hypertrophic Growth
Hanying Chen, Weidong Yong, Shuxun Ren , Weihua Shen , Yongzheng He , Karen A. Cox¶, Wuqiang Zhu , Wei Li , Mark Soonpaa , R. Mark Payne , Diego Franco||, Loren J. Field , Vicki Rosen¶, Yibin Wang , and Weinian Shou J. Biol. Chem.,2006 Sep 15;281(37):27481-91. Epub 2006 Jun 23 |
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Insulin resistance increases PAI-1 in the heart
Burton E. Sobel *, David J. Schneider, Yong-Ho Lee, Richard E. Pratley Biochemical and Biophysical Research Communications 346. 2006 Jul 21;346(1):102-7. Epub 2006 May 22 |
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Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction
Perrino C, Prasad SV, Mao L, Noma T, Yan Z, Kim HS, Smithies O, Rockman HA. J Clin Invest. 2006 Jun;116(6):1547-60. |
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Ultrahigh frame rate retrospective ultrasound microimaging and blood flow visualization in mice in vivo.
Emmanuel Chérin, Ross Williams, Andrew Needles, Godwin Liu, Christopher White, Allison S. Brown, Yu-Qing Zhou and F. Stuart Foster Ultrasound in Medicine & Biology. 2006 May; Vol 32, Issue 5, PP. 683-691 |
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Phospholipase C-{delta}1 Is a Critical Target for Tumor Necrosis Factor Receptor-Mediated Protection against Adriamycin-Induced Cardiac Injury
Lien YC, Noel T, Liu H, Stromberg AJ, Chen KC, St Clair DK. Cancer Res. 2006 Apr 15;66(8):4329-38. |
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Emerging imaging techniques
McVeigh ER. Circ Res. 2006 Apr 14;98(7):879-86. |
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Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome
Jennifer P. Habashi,1 Daniel P. Judge,2 Tammy M. Holm,1 Ronald D. Cohn,1 Bart L. Loeys,1 Timothy K. Cooper,1,3 Loretha Myers,1 Erin C. Klein,1 Guosheng Liu,3 Carla Calvi,2 Megan Podowski,2 Enid R. Neptune,2 Marc K. Halushka,4 Djahida Bedja,3 Kathleen Gabrielson,3 Daniel B. Rifkin,5 Luca Carta,6 Francesco Ramirez,6 David L. Huso,3 Harry C. Dietz1,2 Science. 2006 Apr 7;312(5770):117-21. |
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Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts
Zimmermann WH, Melnychenko I, Wasmeier G, Didie M, Naito H, Nixdorff U, Hess A, Budinsky L, Brune K, Michaelis B, Dhein S, Schwoerer A, Ehmke H, Eschenhagen T. Nat Med. 2006 Apr;12(4):452-8. Epub 2006 Apr 2 |
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Neurogenic Mechanisms Contribute to Hypertension in Mice With Disruption of the K-Cl Cotransporter KCC3
Rust MB, Faulhaber J, Budack MK, Pfeffer C, Maritzen T, Didie M, Beck FX, Boettger T, Schubert R, Ehmke H, Jentsch TJ, Hubner CA. Circ Res,2006 Mar 3;98(4):549-56. Epub 2006 Jan 19 |
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Evaluation of an Algorithm for Semiautomated Segmentation of Thin Tissue Layers in High-Frequency Ultrasound Images
Qiang Qiu, Joy Dunmore-Buyze, Derek R. Boughner, and James C. Lacefield IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 2006 Feb;vol.53, no.2, pg 324-34 |
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Detection of murine infarcts using myocardial elastography at both high temporal and spatial resolution
Jianwen Luo, Kana Fujikura, Konofagou, E.E. Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2006 Jan;1:1552-5 |
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The administration of human ghrelin attenuates development of cardiac cachexia in rats with heart failure
Y Akashi1, J Springer1, S Palus1, R Datta2, H Halem2, J Dong2, M Culler2, S Anker1 Akt Ernähr Med. 2006 Jan; 31 |
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NAD(P)H Oxidase and Multidrug Resistance Protein Genetic Polymorphisms Are Associated With Doxorubicin-Induced Cardiotoxicity
Leszek Wojnowski, MD; Bettina Kulle, PhD; Markus Schirmer, MD; Gregor Schlüter, MD; Albrecht Schmidt, MD; Albert Rosenberger, PhD; Stefan Vonhof, MD; Heike Bickeböller, PhD; Mohammad Reza Toliat, PhD; Eun-Kyung Suk, PhD; Mladen Tzvetkov, PhD; Anke Kruger, PhD; Silvia Seifert, MSc; Marita Kloess, PhD; Heidi Hahn, MD; Markus Loeffler, MD; Peter Nürnberg, PhD; Michael Pfreundschuh, MD; Lorenz Trümper, MD; Jürgen Brockmöller, MD; Gerd Hasenfuss, MD Circulation. 2005 Dec 13;112(24):3754-62. Epub 2005 Dec 5 |
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S100A1 Gene Therapy Preserves in Vivo Cardiac Function after Myocardial Infarction
Sven T. Pleger1,2, Andrew Remppis1, Beatrix Heidt1, Mirko Völkers1, J. Kurt Chuprun2, Matthew Kuhn2, Rui-Hai Zhou2, Erhe Gao2, Gabor Szabo3, Dieter Weichenhan1, Oliver J. Müller1, Andrea D. Eckhart2, Hugo A. Katus1, Walter J. Koch2 and Patrick Most1,2 Molecular Therapy. 2005 Dec;12(6):1120-9. Epub 2005 Sep 15 |
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Image-Guided Cardiac Cell Delivery Using High-Resolution Small-Animal Ultrasound
Rodriguez-Porcel M, Gheysens O, Chen IY, Wu JC, Sam Gambhir S. Molecular Therapy. 2005 Dec;12(6):1142-7. Epub 2005 Aug 18 |
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A novel transgenic mouse model reveals deregulation of the ubiquitin-proteasome system in the heart by doxorubicin
Asangi R. K. Kumarapeli, Kathleen M. Horak, Joseph W. Glasford, Jie Li, Quanhai Chen, Jinbao Liu, Hanqiao Zheng, and Xuejun Wang The FASEB Journal. 2005 Dec;19(14):2051-3. Epub 2005 Sep 27 |
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Low thyroid function leads to cardiac atrophy with chamber dilatation, impaired myocardial blood flow, loss of arterioles, and severe systolic dysfunction
Jennifer L. Lucitti*, Kimimasa Tobita and Bradley B. Keller The Journal of Experimental Biology, 2005 Nov 15;112(20):3122-30. Epub 2005 Nov 7 |
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Comparison of Two Approaches to Volume Quantification for Free-Hand Ultrasound Scanning of Mouse Hearts
C. Garson, Y. Li, and J. Hossack IEEE Ultrasonics Symposium. 2005 Sept 18-21; Vol 1, PP. 491 - 494 |
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Electromechanical imaging of the myocardium at normal and pathological states
Mathieu Pernot and Elisa E. Konofagou IEEE Ultrasonics Symposium. 2005 Sept 18-21; Vol 2, Page(s): 1091 - 1094 |
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Developmental structure-function insights from Tbx5del/+ mouse model of Holt-Oram syndrome
Keller, BB. Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H975-6. |
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Abnormal cardiac inflow patterns during postnatal development in a mouse model of Holt-Oram syndrome
Zhou YQ, Zhu Y, Bishop J, Davidson L, Henkelman RM, Bruneau BG, and Foster FS. Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H992-H1001. Epub 2005 Apr 22 |
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Closed-Chest Cell Injections into Mouse Myocardium Guided by High-Resolution Echocardiography
Springer ML, Sievers RE, Viswanathan MN, Yee MS, Foster E, Grossman W, Yeghiazarians Y. American Journal of Physiology - Heart Circ Physiol. 2005 Sep;289(3):H1307-14. Epub 2005 May 20 |
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Molecular and functional signature of heart hypertrophy during pregnancy
Eghbali M, Deva R, Alioua A, Minosyan TY, Ruan H, Wang Y, Toro L, Stefani E. Circ Res. 2005 Jun 10;96(11):1208-16. Epub 2005 May 19. |
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Imaging the Cardiovascular System: Seeing Is Believing
Thomas K. Borg,, James A. Stewart, Jr., and Michael A. Sutton Microscopy and Microanalysis2005 Jun;11(3):189-99 |
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Introducing the German Mouse Clinic: open access platform for standardized phenotyping
Gailus-Durner V, Fuchs H, Becker L, Bolle I, Brielmeier M, Calzada-Wack J, Elvert R, Ehrhardt N, Dalke C, Franz TJ, Grundner-Culemann E, Hammelbacher S, Holter SM, Holzlwimmer G, Horsch M, Javaheri A, Kalaydjiev SV, Klempt M, Kling E, Kunder S, Lengger C, Lisse T, Mijalski T, Naton B, Pedersen V, Prehn C, Przemeck G, Racz I, Reinhard C, Reitmeir P, Schneider I, Schrewe A, Steinkamp R, Zybill C, Adamski J, Beckers J, Behrendt H, Favor J, Graw J, Heldmaier G, Hofler H, Ivandic B, Katus H, Kirchhof P, Klingenspor M, Klopstock T, Lengeling A, Muller W, Ohl F, Ollert M, Quintanilla-Martinez L, Schmidt J, Schulz H, Wolf E, Wurst W, Zimmer A, Busch DH, de Angelis MH. Nat Methods. 2005 Jun;2(6):403-4. |
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CHIP, a cochaperone/ubiquitin ligase that regulates protein quality control, is required for maximal cardioprotection after myocardial infarction in mice
Chunlian Zhang,1 Zhelong Xu,1,2 Xiao-Rui He,1 Lloyd H. Michael,4 and Cam Patterson1,3 American journal of physiology. Heart and circulatory physiology. 2005 Jun;288(6):H2836-42. Epub 2005 Jan 21 |
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Current mouse models for studying cardiac dysfunctions: technical and imaging aspects
Laurent Monassier*, Catherine Theodoropoulos**, Andre Constantinesco*** Drug Discovery Today: Disease Models. 2004 Dec 17; Vol 1, Issue 3, PP 235-241 |
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TGF-beta-dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome
Connie M. Ng, Alan Cheng, Loretha A. Myers, Francisco Martinez-Murillo, Chunfa Jie, Djahida Bedja, Kathleen L. Gabrielson, Jennifer M.W. Hausladen, Robert P. Mecham, Daniel P. Judge, Harry C. Dietz Journal of Clinical Investigation. 2004 Dec 1 ; 114(11): 1586-1592 |
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Atrogin-1/muscle atrophy F-box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complex
Hui-Hua Li,1 Vishram Kedar,1 Chunlian Zhang,1 Holly McDonough,1 Ranjana Arya,1 Da-Zhi Wang,1,2 and Cam Patterson1,2,3,4 J Clin Invest. 2004 October 15; 114(8): 1058–1071. |
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Comprehensive transthoracic cardiac imaging in mice using ultrasound biomicroscopy with anatomical confirmation by magnetic resonance imaging
Yu-Qing Zhou, F. Stuart Foster, Brian J Nieman, Lorinda Davidson, X. Josette Chen, and R. Mark Henkelman Physiological Genomics. 2004 Jul 8;18(2):232-44 |
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Transgenic rescue of neurogenic atrophy in the nmd mouse reveals a role for Ighmbp2 in dilated cardiomyopathy
Terry P. Maddatu, Sean M. Garvey, David G. Schroeder, Thomas G. Hampton and Gregory A. Cox Human Molecular Genetics2004 Jun 1;13(11):1105-15. Epub 2004 Apr 6 |
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Ultrasound-guided left-ventricular catheterization: a novel method of whole mouse perfusion for microimaging
Zhou YQ, Davidson L, Henkelman RM, Nieman BJ, Foster FS, Yu LX, Chen XJ. Nature Biotechnology; Lab Invest. 2004 Mar;84(3):385-9. |
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Ultrasound biomicroscopy-Doppler in mouse cardiovascular development
Colin K. L. Phoon and Daniel H. Turnbull Physiological Genomics. 2003 Jun 24;14(1):3-15 |
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Maternal cardiovascular changes during pregnancy and postpartum in mice
Alan Y. H. Wong1,2,3, Shathiyah Kulandavelu1,2,3, Kathie J. Whiteley1, Dawei Qu1, B. Lowell Langille1,2,4, and S. Lee Adamson1,2,3 American journal of physiology. Heart and circulatory physiology. 2002 Mar; 282: H918-H925 |
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Constitutive glycogen synthase kinase-3a/� activity protects against chronic �-adrenergic remodelling of the heart
Ian G. Webb1, Yasuhiro Nishino1, James E. Clark1, Colin Murdoch1, Simon J. Walker1, Marcus R. Makowski2, Rene M. Botnar2, Simon R. Redwood1, Ajay M. Shah1 and Michael S. Marber1 Cardiovascular Research. 2010 Mar 18. [Epub ahead of print] |
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Applications - Neonatal Imaging
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Absence of Myocardial Thyroid Hormone Inactivating Deiodinase Results in Restrictive Cardiomyopathy in Mice
Cintia B. Ueta, Behzad N. Oskouei, Emerson L. Olivares, Jose R. Pinto, Mayrin M. Correa, Gordana Simovic, Warner S. Simonides, Joshua M. Hare and Antonio C. Bianco Molecular Endocrinology. 2012 Mar 8. [Epub ahead of print] |
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Abnormal heart development and lung remodeling in mice lacking the hypoxia-inducible factor-related basic helix-loop-helix PAS protein NEPAS
Yamashita T, Ohneda O, Nagano M, Iemitsu M, Makino Y, Tanaka H, Miyauchi T, Goto K, Ohneda K, Fujii-Kuriyama Y, Poellinger L, Yamamoto M. Molecular and Cellular Biology. 2008 Feb;28(4):1285-97. |
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Noninvasive Ultrasonic Measurement Of Regional And Local Pulse-Wave Velocity In Mice
Ross Williams, Andrew Needles, Emmanuel Cherin, Yu-Qing Zhou, R. Mark Henkelman, S. Lee Adamson, And F. Stuart Foster Ultrasound in Med. & Biol. 2007 Sep;33(9):1368-75. Epub 2007 Jun 11 |
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Progressive troponin I loss impairs cardiac relaxation and causes heart failure in mice
Jing Liu,1 Jianfeng Du,1 Chi Zhang,1 Jeffery W. Walker,2 and Xupei Huang1 American journal of physiology. Heart and circulatory physiology. 2007 Aug;293(2):H1273-81. Epub 2007 May 25 |
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Fgl2 deficiency causes neonatal death and cardiac dysfunction during embryonic and postnatal development in mice
Junwu Mu, Dawei Qu, Agata Bartczak, M. James Phillips, Justin Manuel, Wei He, Cheryl Koscik, Michael Mendicino, Li Zhang, David A. Clark, David R. Grant, Peter H. Backx, Gary A. Levy, and S. Lee Adamson Physiol. Genomics. 2007 Sept; 31(1): 53-62, Epub 2007 Jun 5 |
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Initial Experience with High Frequency Ultrasound for the Newborn C57BL Mouse
Alok K. Bose, M.D.*, James W. Mathewson, M.D.*, Brent E. Anderson, B.S.†, Allyson M. Andrews, B.A.*, A. Martin Gerdes, Ph.D.†, M. Benjamin Perryman, Ph.D.† and Paul D. Grossfeld, M.D.* Echocardiography. 2007 Apr; Vol 24, Issue 4, PP. 412-419 |
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Overexpression of Bone Morphogenetic Protein 10 in Myocardium Disrupts Cardiac Postnatal Hypertrophic Growth
Hanying Chen, Weidong Yong, Shuxun Ren , Weihua Shen , Yongzheng He , Karen A. Cox¶, Wuqiang Zhu , Wei Li , Mark Soonpaa , R. Mark Payne , Diego Franco||, Loren J. Field , Vicki Rosen¶, Yibin Wang , and Weinian Shou J. Biol. Chem.,2006 Sep 15;281(37):27481-91. Epub 2006 Jun 23 |
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Abnormal cardiac inflow patterns during postnatal development in a mouse model of Holt-Oram syndrome
Zhou YQ, Zhu Y, Bishop J, Davidson L, Henkelman RM, Bruneau BG, and Foster FS. Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H992-H1001. Epub 2005 Apr 22 |
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Applications - Diabetes
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Trimodal Gadolinium-Gold Microcapsules Containing Pancreatic Islet Cells Restore Normoglycemia in Diabetic Mice and Can Be Tracked by Using US, CT, and Positive-Contrast MR Imaging
Dian R. Arifin, PhD, Christopher M. Long, PhD, Assaf A. Gilad, PhD, Christophe Alric, PhD, Stéphane Roux, PhD, Olivier Tillement, PhD, Thomas W. Link, MS, Aravind Arepally, MD and Jeff W. M. Bulte, PhD Radiology.2011 Jul 6. [Epub ahead of print] |
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Substrate Uptake and Metabolism are Preserved in Hypertrophic Caveolin-3 Knockout Hearts
Augustus AS, Buchanan J, Addya S, Rengo G, Pestell RG, Fortina P, Koch WJ, Bensadoun A, Abel ED, Lisanti MP. American Journal of Physiology, Heart and Circulatory Physiology. 2008 Aug;295(2):H657-66. Epub 2008 Jun 13 |
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Time Course of Alterations in Myocardial Glucose Utilization in the Zucker Diabetic Fatty Rat with Correlation to Gene Expression of Glucose Transporters: A Small-Animal PET Investigation
Shoghi KI, Gropler RJ, Sharp T, Herrero P, Fettig N, Su Y, Mitra MS, Kovacs A, Finck BN, Welch MJ Journal of Nuclear Medicine. 2008 Aug;49(8):1320-7. |
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Acute Metformin Therapy Confers Cardioprotection Against Myocardial Infarction Via AMPK-eNOS-Mediated Signaling
John W. Calvert, Susheel Gundewar, Saurabh Jha, James J.M. Greer, William H. Bestermann, Rong Tian, and David J. Lefer Diabetes. 2008 Mar;57(3):696-705. Epub 2007 Dec 14 |
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Cytoprotective effects of N,N,N-trimethylsphingosine during ischemia- reperfusion injury are lost in the setting of obesity and diabetes
Susheel Gundewar, John W. Calvert, John W. Elrod, and David J. Lefer Am J Physiol Heart Circ Physiol.2007 Oct;293(4):H2462-71. Epub 2007 Jul 13 |
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Insulin resistance increases PAI-1 in the heart
Burton E. Sobel *, David J. Schneider, Yong-Ho Lee, Richard E. Pratley Biochemical and Biophysical Research Communications 346. 2006 Jul 21;346(1):102-7. Epub 2006 May 22 |
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Applications - Liver & Kidney
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A Missense Mutation in the Sodium Phosphate Co-transporter Slc34a1 Impairs Phosphate Homeostasis
Iwaki T, Sandoval-Cooper MJ, Tenenhouse HS, Castellino FJ Journal of the American Society of Nephrology. 2008 Sep;19(9):1753-62. Epub 2008 Jun 11 |
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Uraemic hyperparathyroidism causes a reversible inflammatory process of aortic valve calcification in rats
Shuvy M, Abedat S, Beeri R, Danenberg HD, Planer D, Ben-Dov IZ, Meir K, Sosna J, Lotan C. Cardiovascular Research. 2008 Aug 1;79(3):492-9. |
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Imaging Hypoxia in Orthotopic Rat Liver Tumors with Iodine 124-labeled Iodoazomycin Galactopyranoside PET
Christopher C. Riedl,MD; Peter Brader,MD; Pat B. Zanzonico, PhD; Yun Shin Chun,MD; Yanghee Woo, MD; Paramjeet Singh, MD; Sean Carlin, PhD; Bixiu Wen,MD; C. Clifton Ling, PhD; Hedvig Hricak,MD; Yuman Fong, MD Radiology. 2008 Aug;248(2):561-70 |
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Targeting Notch signaling in autoimmune and lymphoproliferative disease
David T Teachey, Alix E Seif, Valerie I. Brown, Marlo Bruno, Ralph M Bunte, Yueh J Chang, John K Choi, Jonathan D Fish, Junior Hall, Gregor S Reid, Theresa Ryan, Cecilia Sheen, Patrick Zweidler-McKay, and Stephan A. Grupp Blood. 2008 Jan 15;111(2):705-14. |
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Monitoring kidney safety in drug development: Emerging technologies and their implications
Frank Dieterle1, Estelle Marrer1, Eiko Suzuki2, Olivier Grenet3,Andre Cordier1 & Jacky Vonderscher1 Current Opinion in Drug Discovery & Development. 2008 Jan;11(1):60-71 |
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Ultrasound biomicroscopy permits in vivo characterization of zebrafish liver tumors
Goessling W, North TE, Zon LI. Nat Methods. 2007 Jul;4(7):551-3. Epub 2007 Jun 17 |
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Imaging kidney in conscious rats with high-frequency ultrasound and detection of two cases of unilateral congenital hydronephrosis
Wang YX, Betton G, Floettmann E, Fantham E, Ridgwell G. Ultrasound Med Biol. 2007 Mar;33(3):483-6; Epub 2006 Dec 21 |
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Oncolytic Viral Therapy By Bladder Instillation Using An E1a, E1b Double-Restricted Adenovirus In An Orthotopic Bladder Cancer Model
Hua Wang, Makoto Satoh, Hisashi Abe, Makoto Sunamura, Takuya Moriya, Shigeto Ishidoya, Seiichi Saito, Hirofumi Hamada, And Yoichi Arai Urology, 2006 Sep;68(3):674-81. Epub 2006 Sep 18 |
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Volume measurement variability in three-dimensional high-frequency ultrasound images of murine liver metastases
Wirtzfeld LA, Graham KC, Groom AC, Macdonald IC, Chambers AF, Fenster A, Lacefield JC. Phys Med Biol. 2006 May 21;51(10):2367-81. Epub 2006 Apr 26. |
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Three-dimensional High-Frequency Ultrasound Imaging for Longitudinal Evaluation of Liver Metastases in Preclinical Models
Graham KC, Wirtzfeld LA, Mackenzie LT, Postenka CO, Groom AC, Macdonald IC, Fenster A, Lacefield JC, Chambers AF. Cancer Research. 2005 Jun 15;65(12):5231-7. |
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High-frequency ultrasound for monitoring changes in liver tissue during preservation
Vlad RM, Czarnota GJ, Giles A, Sherar MD, Hunt JW, Kolios MC. Physics in Medicine & Biology. 2005 Jan 21;50(2):197-213. |
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A functional floxed allele of Pkd1 that can be conditionally inactivated in vivo
Piontek KB, Huso DL, Grinberg A, Liu L, Bedja D, Zhao H, Gabrielson K, Qian F, Mei C, Westphal H, Germino GG. Journal of the American Society of Nephrology. 2004 Dec;15(12):3035-43. |
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Applications - Zebrafish Imaging
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Ultrasound biomicroscopy permits in vivo characterization of zebrafish liver tumors
Goessling W, North TE, Zon LI. Nat Methods. 2007 Jul;4(7):551-3. Epub 2007 Jun 17 |
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Applications - Chick Imaging
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Tendon adhesion measured by a video-assisted gliding test in a chicken model
S.-C. Fu, L.-K. Hung, Y.-W. Lee, T.-Y. Mok, K.-M. Chan The Journal of Hand Surgery (European Volume). 2011 Jan;36(1):40-7. Epub 2010 Sep 3 |
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Two-photon microscopy-guided femtosecond-laser photoablation of avian cardiogenesis: noninvasive creation of localized heart defects
Huseyin C. Yalcin, Akshay Shekhar, Nozomi Nishimura, Ajinkya A. Rane, Chris B. Schaffer, and Jonathan T. Butcher American Journal of Physiology. Heart and Circulatory Physiology. 2010 Nov;299(5):H1728-35. Epub 2010 Aug 13 |
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Doppler flow velocity waveforms in the embryonic chicken heart at developmental stages corresponding to 5-8 weeks of human gestation
A. M. Oosterbaan 1, N. T. C. Ursem 1, P. C. Struijk 1, J. G. Bosch 2, A. F. W. van der Steen 2, E. A. P. Steegers 1 Ultrasound in Obstetrics & Gynecology. 2009 Jun;33(6):638-44 |
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High-frequency ultrasonographic imaging of avian cardiovascular development
Tim C. McQuinn1 2Momka Bratoeva1, Angela DeAlmeida1, Mathieu Remond1, Robert P. Thompson1, David Sedmera1 3 4 Developmental Dynamics2007 Dec;236(12):3503-13 |
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Finite element modeling of blood flow-induced mechanical forces in the outflow tract of chick embryonic hearts
Aiping Liu, Sandra Rugonyi, Jeffrey O. Pentecost, Kent L. Thornburg Computers and Structures. 2007 Jun-Jul; 85(11-14):727–738 |
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Transitions in Early Embryonic Atrioventricular Valvular Function Correspond With Changes in Cushion Biomechanics That Are Predictable by Tissue Composition
Jonathan T. Butcher, Tim C. McQuinn, David Sedmera, Debi Turner, Roger R. Markwald Circulation Research. 2007 May 25;100(10):1503-11. Epub 2007 May 3 |
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Applications - Contrast and Molecular Imaging
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Novel Genetic Approach for In Vivo Vascular Imaging in Mice
Benjamin B. Bartelle, César A. BerrÃos-Otero, Joe J. Rodriguez, Anne E. Friedland, Orlando Aristizábal, Daniel H. Turnbull Circulation Research. 2012 Mar 30;110(7):938-47. Epub 2012 Feb 28 |
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Quantification and Monitoring of Inflammation in Murine Inflammatory Bowel Disease with Targeted Contrast-enhanced US
Nirupama Deshpande, PhD, Amelie M. Lutz, MD, Ying Ren, MD, Kira Foygel, PhD, Lu Tian, PhD, Michel Schneider, PhD, Reetesh Pai, MD, Pankaj J. Pasricha, MD and Jürgen K. Willmann, MD Radiology. 2012 Jan;262(1):172-80. Epub 2011 Nov 4 |
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Dual Inhibition of the PI3K/mTOR Pathway Increases Tumor Radiosensitivity by Normalizing Tumor Vasculature
Emmanouil Fokas1, Jae Hong Im1, Sally Hill1, Sabira Yameen1, Michael Stratford1, John Beech1, Wolfgang Hackl2, Sauveur-Michel Maira2, Eric J. Bernhard1, W. Gillies McKenna1, and Ruth J. Muschel1 Cancer Research. 2012 Jan 1;72(1):239-48. Epub 2011 Nov 22 |
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Relationship of glucose and oleate metabolism to cardiac function in lipin-1 deficient (fld) mice
Bernard P. C. Kok1, Petra C. Kienesberger2,3, Jason R. B. Dyck2,3, and David N. Brindley1,3 Journal of Liped Research. 2012 Jan;53(1):105-18. Epub 2011 Nov 5 |
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Mice With Cardiac Overexpression of Peroxisome Proliferator–Activated Receptor γ Have Impaired Repolarization and Spontaneous Fatal Ventricular Arrhythmias
John P. Morrow, MD; Alexander Katchman, PhD; Ni-Huiping Son, MD; Chad M. Trent, BS; Raffay Khan, MD; Takayuki Shiomi, MD; Haiyan Huang, MD, PhD; Vaibhav Amin, BS; Joshua M. Lader, MD; Carolina Vasquez, PhD; Gregory E. Morley, PhD; Jeanine D\'Armiento, MD, PhD; Shunichi Homma, MD; Ira J. Goldberg, MD; Steven O. Marx, MD Circulation. 2011 Dec 20;124(25):2812-21. Epub 2011 Nov 28 |
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Bioengineered human vascular networks transplanted into secondary mice reconnect with the host vasculature and re-establish perfusion
Kyu-Tae Kang1, Patrick Allen1,2, and Joyce Bischoff1 Blood. 2011 Dec 15;118(25):6718-21. Epub 2011 Oct 28 |
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Doxycycline reduces fibril formation in a transgenic mouse model of AL amyloidosis
Jennifer Ellis Ward1,2, Ruiyi Ren1,3, Gianluca Toraldo2, Pam SooHoo1,4, Jian Guan1,2, Carl O\'Hara1,4, Ravi Jasuja2, Vickery Trinkaus-Randall1,3, Ronglih Liao5, Lawreen H. Connors1,3, and David C. Seldin1,2 Blood. 2011 Dec 15;118(25):6610-7. Epub 2011 Oct 12 |
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Acute myocardial infarction activates progenitor cells and increases Wnt signalling in the bone marrow
Birgit Assmus1, Masayoshi Iwasaki2, Volker Schächinger1, Tino Roexe2, Masamichi Koyanagi2, Kazuma Iekushi2, Quanfu Xu2, Torsten Tonn3, Erhard Seifried3, Stefan Liebner4, Wolfgang Tilman Kranert5, Frank Grünwald5, Stefanie Dimmeler2 and Andreas M. Zeiher1 European Heart Journal. 2011 Dec 15. [Epub ahead of print] |
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Pathogenesis of lethal cardiac arrhythmias in mecp2 mutant mice: implication for therapy in rett syndrome
Mark D. McCauley1,2, Tiannan Wang1, Elise Mike1, Jose Herrera3, David L. Beavers1,2, Teng-Wei Huang4, Christopher S. Ward5, Steven Skinner6, Alan K. Percy7, Daniel G. Glaze8, Xander H. T. Wehrens1,2,3, and Jeffrey L. Neul1,3,4,5,9,10 Science Translational Medicine. 2011 Dec 14;3(113):113ra125 |
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Proangiogenic Factor PlGF Programs CD11b+ Myelomonocytes in Breast Cancer during Differentiation of Their Hematopoietic Progenitors
Julien Laurent1, Eveline Faes-van\'t Hull1, Cedric Touvrey1, François Kuonen1, Qiang Lan1,5, Girieca Lorusso1,5, Marie-Agnès Doucey1, Laura Ciarloni1, Natsuko Imaizumi1, Gian Carlo Alghisi1, Ernesta Fagiani7, Khalil Zaman2, Roger Stupp4, Masabumi Shibuya8, Jean-François Delaloye3, Gerhard Christofori5,7, and Curzio Ruegg1,5,6 Cancer Research. 2011 Jun 1;71(11):3781-3791. Epub 2011 Apr 20 |
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Assessing vesicoureteral reflux in live inbred mice via ultrasound with a microbubble contrast agent
Jose Paredes1, Sunder Sims-Lucas1, Hang Wang2, Weining Lu2, Brian Coley3, George K. Gittes1,4, and Carlton M. Bates1,5 American Journal of Physiology. Renal Physiology. 2011 May;300(5):F1262-5. Epub 2011 Feb 16 |
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Spontaneous Pregnancy Loss Mediated by Abnormal Maternal Inflammation in Rats Is Linked to Deficient Uteroplacental Perfusion
Stephen J. Renaud, Tiziana Cotechini, Jill S. Quirt, Shannyn K. Macdonald-Goodfellow, Maha Othman and Charles H. Graham The Journal of Immunology. 2011 Feb 1;186(3):1799-808. Epub 2010 Dec 27 |
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Nonlinear contrast imaging with an array-based micro-ultrasound system
Needles A, Arditi M, Rognin NG, Mehi J, Coulthard T, Bilan-Tracey C, Gaud E, Frinking P, Hirson D, Foster FS Ultrasound in Medicine and Biology. 2010 Dec;36(12):2097-106. |
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Molecular Imaging of Vasa Vasorum Neovascularization via DEspR-targeted Contrast-enhanced Ultrasound Micro-imaging in Transgenic Atherosclerosis Rat Model
Julius L. Decano, Anne Marie Moran, Nelson Ruiz-Opazo, Victoria L. M. Herrera Molecular Imaging and Biology. 2010 Oct 23. [Epub ahead of print] |
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Anti–αv Integrin Monoclonal Antibody Intetumumab Enhances the Efficacy of Radiation Therapy and Reduces Metastasis of Human Cancer Xenografts in Nude Rats
Shoucheng Ning1, Junqiang Tian1, Deborah J. Marshall2, and Susan J. Knox1 Cancer Research. 2010 Oct 1;70(19):7591-9. Epub 2010 Sep 14 |
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A Statistical Model for the Quantification of Microbubbles in Destructive Imaging
Monica Siepmann, Michael Reinhardt and Georg Schmitz, PhD Investigative Radiology. 2010 Aug 20. [Epub ahead of print] |
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Alterations in membrane type-1 matrix metalloproteinase abundance after the induction of thoracic aortic aneurysm in a murine model
Jeffrey A. Jones,1,2 Jean Marie Ruddy,1 Shenikqua Bouges,1 Juozas A. Zavadzkas,1 Theresa A. Brinsa,1 Robert E. Stroud,1 Rupak Mukherjee,1 Francis G. Spinale,1,2 and John S. Ikonomidis1 American Journal of Physiology. Heart and Circulatory Physiology. 2010 Jul;299(1):H114-24. Epub 2010 Apr 23 |
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Molecular ultrasound imaging: current status and future directions
N. Deshpande 1, A.Needles 2, J.K.Willmann 1 Clinical Radiology. 2010 Jul;65(7):567-81 |
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Effect of microbubble size on fundamental mode high frequency ultrasound imaging in mice
Shashank Sirsi1, Jameel Feshitan1, James Kwan1, Shunichi Homma2 and Mark Borden1 Ultrasound in Medicine & Biology. 2010 Jun;36(6):935-48. Epub 2010 May 5 |
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Antiangiogenic Cancer Therapy: Monitoring with Molecular US and a Clinically Translatable Contrast Agent (BR55)
Marybeth A. Pysz, PhD, Kira Foygel, PhD, Jarrett Rosenberg, PhD, Sanjiv S. Gambhir, MD, PhD, Michel Schneider, PhD and Jürgen K. Willmann, MD Radiology. 2010 Jun 1. [Epub ahead of print] |
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Correlation of Quantified Contrast-Enhanced Sonography With In Vivo Tumor Response
Misun Hwang, BS, Ghazal Hariri, MS, Andrej Lyshchik, MD, PhD, Dennis E. Hallahan, MD and Arthur C. Fleischer, MD Journal of Ultrasound in Medicine. 2010 Apr;29(4):597-607 |
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Targeted Contrast-Enhanced Ultrasound Imaging of Tumor Angiogenesis with Contrast Microbubbles Conjugated to Integrin-Binding Knottin Peptides
Jürgen K. Willmann 1, Richard H. Kimura 2, Nirupama Deshpande 1, Amelie M. Lutz 1, Jennifer R. Cochran 3, and Sanjiv S. Gambhir 2 The Journal of Nuclear Medicine. 2010 Mar;51(3):433-40. Epub 2010 Feb 11 |
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IFN-ß Restricts Tumor Growth and Sensitizes Alveolar Rhabdomyosarcoma to Ionizing Radiation
Thomas L. Sims1,4, Mackenzie McGee1, Regan F. Williams1,4, Adrianne L. Myers1,4, Lorraine Tracey1, J. Blair Hamner1,4, Catherine Ng1, Jianrong Wu2, M. Waleed Gaber5, Beth McCarville3, Amit C. Nathwani6 and Andrew M. Davidoff1,4 Molecular Cancer Therapeutics. 2010 Mar;9(3):761-71. Epub 2010 Mar 2 |
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Molecular Imaging of Myocardial and Vascular Disorders With Ultrasound
Jonathan R. Lindner, MD JACC. Cardiovascular Imaging. 2010 Feb;3(2):204-211 |
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Cardiomyocyte PDGFR-ß signaling is an essential component of the mouse cardiac response to load-induced stress
Vishnu Chintalgattu,1 Di Ai,1 Robert R. Langley,2 Jianhu Zhang,1 James A. Bankson,3 Tiffany L. Shih,1 Anilkumar K. Reddy,4 Kevin R. Coombes,5 Iyad N. Daher,1 Shibani Pati,6 Shalin S. Patel,1 Jennifer S. Pocius,4 George E. Taffet,4 L. Maximillian Buja,7 Mark L. Entman,4 and Aarif Y. Khakoo1 The Journal of Clinical Investigation. 2010 Feb 1;120(2):472-84. Epub 2010 Jan 11 |
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Mature dendritic cells use endocytic receptors to capture and present antigens
Craig D. Platt1,2,3, Jessica K. Ma1,3, Cécile Chalouni3, Melanie Ebersold1, Hani Bou-Reslan3, Richard A. D. Carano3, Ira Mellman3, and Lélia Delamarre3 Proceedings of the National Academy of Sciences of the United States of America. 2010 Jan 11. [Epub ahead of print] |
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A method for differentiating targeted microbubbles in real time using subharmonic micro-ultrasound and interframe filtering
A. Needles, O. Couture and F.S. Foster Ultrasound in Medicine & Biology. 2009 Sep;35(9):1564-73. Epub 2009 Jul 25 |
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Coregistration of ultrasonography and magnetic resonance imaging with a preliminary investigation of the spatial colocalization of vascular endothelial growth factor receptor 2 expression and tumor perfusion in a murine tumor model
Mary E. Loveless, Jennifer G. Whisenant, Kevin Wilson, Andrej Lyshchik, Tuhin K. Sinha, John C. Gore, Thomas E. Yankeelov Molecular Imaging. 2009 Jul-Aug;8(4):187-98 |
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Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer
Kenneth P. Olive 1, Michael A. Jacobetz 1, Christian J. Davidson 2, Aarthi Gopinathan 3, Dominick McIntyre 1, Davina Honess 1, Basetti Madhu 1, Mae A. Goldgraben 1, Meredith E. Caldwell 1, David Allard 1, Kristopher K. Frese 1, Gina DeNicola 3, Christine Feig 1, Chelsea Combs 2, Stephen P. Winter 1, Heather Ireland 1, Stefanie Reichelt 1, William J. Howat 1, Alex Chang 4, Mousumi Dhara 4, Lifu Wang 5, Felix Rückert 6, Robert Grützmann 6, Christian Pilarsky 6, Kamel Izeradjene 7, Sunil R. Hingorani 7, Pearl Huang 8, Susan E. Davies 9, William Plunkett 10, Merrill Egorin 11, Ralph H. Hruban 4, Nigel Whitebread 12, Karen McGovern 12, Julian Adams 12, Christine Iacobuzio-Donahue 4, John Griffiths 1, David A. Tuveson 1 Sciencexpress. 2009 Jun 12;324(5933):1457-61. Epub 2009 May 21 |
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Novel Use of Ultrasound to Examine Regional Blood Flow in the Mouse Kidney
Jennifer C. Sullivan1, Bin Wang1, Erika I Boesen1, Gerard D'Angelo2, Jennifer S. Pollock1, and David M. Pollock1 American Journal of Physiology, Renal Physiology. 2009 Jul;297(1):F228-35. Epub 2009 May 6 |
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Sunitinib and PF-562,271 (FAK/Pyk2 inhibitor) effectively block growth and recovery of human hepatocellular carcinoma in a rat xenograft model
Cedo M. Bagi,1 James Christensen,2 Darrel P. Cohen,2 Walter G. Roberts,3 Dean Wilkie,4 Terri Swanson,1 Theresa Tuthill5 and Catharine J. Andresen1 Cancer Biology & Therapy. 2009 May;8(9):856-65 |
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Real-Time Quantitation of Renal Ischemia Using Targeted Microbubbles: In-vivo Measurement of P-selectin Expression
Sero Andonian, Tonya Coulthard, Arthur D Smith, Pravin S Singhal, and Benjamin R Lee Journal of endourology. 2009 Mar;23(3):373-8 |
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Acoustic and Kinetic Behaviour of Definity in Mice Exposed to High Frequency Ultrasound
Shawn Stapleton1,2, Heather Goodman2, Yu-Qing Zhou3, Emmanuel Cherin2, R. Mark Henkelman1,3, Peter N. Burns1,2, F. Stuart Foster1,2,3 Ultrasound in Medicine & Biology. 2009 Feb;35(2):296-307. Epub 2008 Oct 31 |
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Targeted Microbubbles for Imaging Tumor Angiogenesis: Assessment of Whole-Body Biodistribution with Dynamic Micro-PET in Mice
Jürgen K. Willmann, MD; Zhen Cheng, PhD; Corrine Davis, DVM, PhD; Amelie M. Lutz, MD; Meike L. Schipper, MD; Carsten H. Nielsen, BS; Sanjiv S. Gambhir, MD, PhD Radiology. 2008 Oct; 249(1): 212-9 |
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Dual-targeted Contrast Agent for US Assessment of Tumor Angiogenesis in Vivo
Jürgen K. Willmann, MD; Amelie M. Lutz, MD; Ramasamy Paulmurugan, PhD; Manishkumar R. Patel, PhD; Pauline Chu, BA; Jarrett Rosenberg, PhD; Sanjiv S. Gambhir, MD, PhD Radiology. 2008 Sep;248(3):936-44 |
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High-frequency subharmonic pulsed-wave Doppler and color flow imaging of microbubble contrast agents
Needles A, Goertz DE, Karshafian R, Cherin E, Brown AS, Burns PN, Foster FS Ultrasound in Medicine and Biology. 2008 Jul;34(7):1139-51. |
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Relationship between retention of a vascular endothelial growth factor receptor 2 (VEGFR2)-targeted ultrasonographic contrast agent and the level of VEGFR2 expression in an in vivo breast cancer model
Lee DJ, Lyshchik A, Huamani J, Hallahan DE, Fleischer AC Journal of Ultrasound in Medicine. 2008 Jun;27(6):855-66. |
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Volumetric high-frequency Doppler ultrasound enables the assessment of early antiangiogenic therapy effects on tumor xenografts in nude mice
Jugold M, Palmowski M, Huppert J, Woenne EC, Mueller MM, Semmler W, Kiessling F. Eur Radiol. 2008 Apr;18(4):753-8. Epub 2007 Dec 15 |
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US Imaging of Tumor Angiogenesis with Microbubbles Targeted to Vascular Endothelial Growth Factor Receptor Type 2 in Mice
Jürgen K. Willmann, MD; Ramasamy Paulmurugan, PhD; Kai Chen, PhD; Olivier Gheysens, MD; Martin Rodriguez-Porcel, MD; Amelie M. Lutz, MD; Ian Y. Chen, MSE; Xiaoyuan Chen, PhD; Sanjiv S. Gambhir, MD, PhD Radiology. 2008 Feb; 246(2):508-18. Epub 2008 Jan 7 |
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Molecular Imaging Of Vascular Endothelial Growth Factor Receptor 2 Expression Using Targeted Contrast-Enhanced High-Frequency Ultrasonography
Lyshchik A, Fleischer AC, Huamani J, Hallahan DE, Brissova M, Gore JC J Ultrasound Med. 2007 Nov;26(11):1575-86. |
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Improved Myocardial Motion Tracking in Mouse Echocardiography using Large-Diameter Microbubbles
Yinbo Li, Christopher D. Garson, Yaqin Xu, Brent A. French and John A. Hossack Ultrasonics Symposium, 2007. IEEE. 2007 Oct 28-31; PP. 892 - 895 |
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Microultrasound Molecular Imaging of Vascular Endothelial Growth Factor Receptor 2 in a Mouse Model of Tumor Angiogenesis
Joshua J. Rychak, James Graba, Alison M.Y. Cheung, Bina S. Mystry, Jonathan R. Lindner, Robert S. Kerbel, and F. Stuart Foster Molecular Imaging. 2007 Sep-Oct; 6(5): PP. 289–296 |
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Biodegradable nanoparticles for targeted ultrasound imaging of breast cancer cells in vitro
Jun Liu, Jie Li, Thomas J Rosol, Xueliang Pan and Jeffrey L Voorhees PHYSICS IN MEDICINE AND BIOLOGY,2007 Aug 21;52(16):4739-47. Epub 2007 Jul 24 |
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Molecular Imaging of Inflammation in Atherosclerosis With Targeted Ultrasound Detection of Vascular Cell Adhesion Molecule-1
Beat A. Kaufmann, MD; John M. Sanders, BS; Christopher Davis, MD; Aris Xie, MS; Patrick Aldred, MS; Ian J. Sarembock, MB, ChB; Jonathan R. Lindner, MD Circulation. 2007 Jul 17;116(3):276-84. Epub 2007 Jun 25 |
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Ultrasound biomicroscopy permits in vivo characterization of zebrafish liver tumors
Goessling W, North TE, Zon LI. Nat Methods. 2007 Jul;4(7):551-3. Epub 2007 Jun 17 |
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Properties of an entropy-based signal receiver with an application to ultrasonic molecular imaging
M. S. Hughes, J. E. McCarthy , J. N. Marsh, J. M. Arbeit, R. G. Neumann, R. W. Fuhrhop, K. D. Wallace, and D. R. Znidersic, B. N. Maurizi , S. L. Baldwin, G. M. Lanza, and S. A. Wickline The Journal of the Acoustical Society of America,2007 Jun;121(6):3542-57 |
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High-Resolution Myocardial Perfusion Imaging in Mice with High-Frequency Echocardiographic Detection of a Depot Contrast Agent
Beat A. Kaufmann, MDab, Miles Lankford, BSb, Carolyn Z. Behm, MDb, Brent A. French, PhDb, Alexander L. Klibanov, PhDb, Yaqin Xu, MD, PhDb, Jonathan R. Lindner. J of Am Society of Echo. 2007 Feb; Vol 20, Issue 2, PP. 136-143 |
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Excitation of polymer-shelled contrast agents with high-frequency ultrasound
Ketterling JA, Mamou J, Allen JS 3rd, Aristizábal O, Williamson RG, Turnbull DH. J Acoust Soc Am. 2007 Jan;121(1):EL48-53. |
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Nanoparticles as image enhancing agents for ultrasonography
Liu J, Levine AL, Mattoon JS, Yamaguchi M, Lee RJ, Pan X, Rosol TJ. Phys Med Biol. 2006 May 7;51(9):2179-89. Epub 2006 Apr 10 |
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Investigating perfluorohexane particles with high-frequency ultrasound
Couture O, Bevan PD, Cherin E, Cheung K, Burns PN, Foster FS. Ultrasound Med Biol. 2006 Jan;32(1):73-82. |
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Ultrasonic Molecular Imaging of Primordial Angiogenic Vessels in Rabbit and Mouse Models With v3-integrin Targeted Nanoparticles Using Information-Theoretic Signal Detection: Results at High Frequency and in the Clinical Diagnostic Frequency Range
M. Hughes, J. N. Marsh, Jeffrey Arbeit, Robert Neumann,R. W. Fuhrhop, G. M. Lanza, and S. A. Wickline IEEE Ultrasonics Symposium. 2005 Sept 18-21; Vol: 1, PP. 617- 620 |
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High-frequency, nonlinear flow imaging of microbubble contrast agents
Goertz DE, Needles A, Burns PN, Foster FS. IEEE Trans Ultrason Ferroelectr Freq Control. 2005 Mar;52(3):495-502. |
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High Frequency Nonlinear B-Scan Imaging of Microbubble Contrast Agents
David E. Goertz, Emmanuel Cherin, Andrew Needles, Raffi Karshafian, Allison S. Brown, Peter N. Burns, and F. Stuart Foster IEEE Ultrasonics, Ferroelectrics, And Frequency Control Society. 2005 Jan; Vol. 52, Issue 1 |
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The role of ultrasound in molecular imaging
Liang HD, Blomley MJ. British Journal of Radiology. 2003 Dec;76 Spec No 2:S140-50. |
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Applications - Vascular Biology
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A Central Role for CD68(+) Macrophages in Hepatopulmonary Syndrome: Reversal by Macrophage Depletion
Thenappan Thenappan1, Ankush Goel1, Glenn Marsboom1, Yong-Hu Fang1, Peter T Toth1, Hannah J Zhang1, Hidemi Kajimoto2, Zhigang Hong1, Jonathan Paul1, Christian Wietholt1, Jennifer Pogoriler1, Lin Piao1, Jalees Rehman1, and Stephen L Archer1 American Journal of Respiratory and Creitical Care Medicine. 2011 Apr 15;183(8):1080-91. Epub 2010 Dec 10 |
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Haploinsufficiency of the murine Col3a1 locus causes aortic dissection: a novel model of the vascular type of Ehlers–Danlos syndrome
Lee B. Smith1, Patrick W.F. Hadoke2, Emma Dyer1, Martin A. Denvir2, David Brownstein2, Eileen Miller2, Nancy Nelson1, Sara Wells3, Michael Cheeseman3,4 and Andy Greenfield4 Cardiovascular Research. 2011 Apr 1;90(1):182-90. Epub 2010 Nov 10 |
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p190 RhoGTPase-Activating Protein Links the ß1 Integrin/Caveolin-1 Mechanosignaling Complex to RhoA and Actin Remodeling
Baohua Yang; Chris Radel; Dalton Hughes; Sheri Kelemen; Victor Rizzo Arteriosclerosis, Thrombosis and Vascular Biology. 2011 Feb;31(2):376-83. Epub 2010 Nov 4 |
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Matrix Metalloproteinase 2 and 9 Dysfunction Underlie Vascular Stiffness in Circadian Clock Mutant Mice
Ciprian B. Anea; M. Irfan Ali; Jessica M. Osmond; Jennifer C. Sullivan; David W. Stepp; Ana M. Merloiu; R. Daniel Rudic Arteriosclerosis, Thrombosis, and Vascular Biology2010 Dec;30(12):2535-43. Epub 2010 Sep 9 |
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Temporal Characterization of the Functional Density of the Vasa Vasorum by Contrast-Enhanced Ultrasonography Maximum Intensity Projection Imaging
Sang Chol Lee, MD1,2, Chad L. Carr, MD1, Brian P. Davidson, MD1, Dilantha Ellegala, MD1, Aris Xie, MS1, Azzdine Ammi, PhD1, Todd Belcik, BS, RDCS1, Jonathan R. Lindner, MD1 The American College of Cardiology Foundation JACC Cardiovascular Imaging. 2010 Dec;3(12):1265-72 |
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A ZASP Missense Mutation, S196L, Leads to Cytoskeletal and Electrical Abnormalities in a Mouse Model of Cardiomyopathy
Zhaohui Li, MD, PhD, Tomohiko Ai, MD, PhD, Kaveh Samani, MD, Yutao Xi, PhD, Huei-Ping Tzeng, PhD, Mingxing Xie, MD, Shan Wu, MD, Shuping Ge, MD, Michael D. Taylor, MD, PhD, Jian-Wen Dong, MD, PhD, Jie Cheng, MD, PhD, Michael J. Ackerman, MD, PhD, Akinori Kimura, MD, Gianfranco Sinagra, MD, Luca Brunelli, MD, PhD, Georgine Faulkner, PhD and Matteo Vatta, PhD Circulation: Arrhythmia and Electrophysiology. 2010 Dec 1;3(6):646-56. Epub 2010 Sep 18 |
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Molecular Imaging of Vasa Vasorum Neovascularization via DEspR-targeted Contrast-enhanced Ultrasound Micro-imaging in Transgenic Atherosclerosis Rat Model
Julius L. Decano, Anne Marie Moran, Nelson Ruiz-Opazo, Victoria L. M. Herrera Molecular Imaging and Biology. 2010 Oct 23. [Epub ahead of print] |
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Transcutaneous very-high-resolution ultrasound to quantify arterial wall layers of muscular and elastic arteries: validation of a method
Taisto Sarkola1, Andrew Redington1,2, Fred Keeley2, Timothy Bradley1, Edgar Jaeggi1,2 Atherosclerosis. 2010 Oct;212(2):516-23. Epub 2010 Jul 7 |
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High-resolution ultrasound showing increased intima and media thickness of the radial artery in patients with end-stage renal disease
Mats Johansson1,2, Anna Myredal1,2, Peter Friberg2, Li Ming Gan2 Atherosclerosis. 2010 Feb 1. [Epub ahead of print] |
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In vivo characterization of the aortic wall stress–strain relationship
Asawinee Danpinida,b, Jianwen Luob, Jonathan Vappoub, Pradit Terdtoona and Elisa E. Konofagoub Ultrasonics. 2010 Jan 13. [Epub ahead of print] |
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Mature dendritic cells use endocytic receptors to capture and present antigens
Craig D. Platt1,2,3, Jessica K. Ma1,3, Cécile Chalouni3, Melanie Ebersold1, Hani Bou-Reslan3, Richard A. D. Carano3, Ira Mellman3, and Lélia Delamarre3 Proceedings of the National Academy of Sciences of the United States of America. 2010 Jan 11. [Epub ahead of print] |
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Spontaneous Adult-Onset Pulmonary Arterial Hypertension Attributable to Increased Endothelial Oxidative Stress in a Murine Model of Hereditary Hemorrhagic Telangiectasia
Mourad Toporsian ; Mirjana Jerkic ; Yu-Qing Zhou ; Mohammed G. Kabir ; Lisa X. Yu ; Brendan A. S. McIntyre ; Adrienne Davis ; Yu Jing Wang ; Duncan J. Stewart ; Jaques Belik ; Mansoor Husain ; Mark Henkelman ; and Michelle Letarte Arteriosclerosis, Thrombosis, and Vascular Biology. 2010 Mar;30(3):509-17. Epub 2009 Dec 30 |
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Torcetrapib Produces Endothelial Dysfunction Independent of CETP Inhibition
Connelly, Margery A PhD; Parry, Tom J PhD; Giardino, Edward C BS; Huang, Zhihong BS; Cheung, Wai-man BS; Chen, Cailin PhD; Cools, Frank BS; Van der Linde, Henk BS; Gallacher, David J PhD; Kuo, Gee-Hong PhD; Sarich, Troy C PhD; Demarest, Keith T PhD; Damiano, Bruce P PhD Journal of Cardiovascular Pharmacology. 2010 [Epub ahead of print] 2009 Dec 31. |
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Effects of fasudil on early atherosclerotic plaque formation and established lesion progression in apolipoprotein E-knockout mice
Duo-Jiao Wu1, Jian-Zhong Xu1, Yong-JieWu1, Lafarge Jean-Charles2, Bing Xiao1, Ping-Jin Gao1,3, Ding-Liang Zhu1,2 Atherosclerosis. 2009 Nov;207(1):68-73. Epub 2009 Apr 24 |
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Molecular Imaging of the Initial Inflammatory Response in Atherosclerosis. Implications for Early Detection of Disease
Beat A. Kaufmann ; Chad L. Carr ; J. Todd Belcik ; Aris Xie ; Qi Yue ; Scott Chadderdon ; Evan S. Caplan ; Jaspreet Khangura ; Sherry Bullens ; Stuart Bunting ; and Jonathan R. Lindner Arteriosclerosis, Thrombosis, and Vascular Biology. 2010 Jan;30(1):54-9. Epub 2009 Oct 15 |
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In vivo, Noninvasive, Label-Free Detection and Eradication of Circulating Metastatic Melanoma Cells Using Two-Color Photoacoustic Flow Cytometry with a Diode Laser
Ekaterina I. Galanzha 1, 2, Evgeny V. Shashkov 1, Paul M. Spring 2, James Y. Suen 2, and Vladimir P. Zharov 1, 2 Cancer Research. 2009 Oct 15;69(20):7926-34. Epub 2009 Oct 13 |
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Blood velocity measurement in the posterior segment of the rabbit eye using combined spectral Doppler and power Doppler ultrasound
Walid Abdallah1, Amani Fawzi1,2, Hitenkumar Patel3, Grant Dagliyan3, Naoki Matsuoka1, Edward Grant4 and Mark Humayun1, 2, 5, 6 Graefe's Archive for Clinical and Experimental Opthalmology. 2010 Jan;248(1):93-101. Epub 2009 Oct 3 |
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Increased intima thickness of the radial artery in patients with coronary heart disease
Anna Myredal1, Walter Osika2, Li Ming Gan2, Peter Friberg2, and Mats Johansson1 Vascular Medicine. 2010 Feb;15(1):33-7. Epub 2009 Sep 25 |
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Outflow tract cushions perform a critical valve-like function in the early embryonic heart requiring BMPRIA-mediated signaling in cardiac neural crest
Aya Nomura-Kitabayashi1, Colin K.L. Phoon2, Satoshi Kishigami1, Julie Rosenthal3, Yasutaka Yamauchi4, Kuniya Abe4, Ken-ichi Yamamura4, Rajeev Samtani3, Cecilia W. Lo5, and Yuji Mishina6 American Journal of Physiology, Heart and Circulatory Physiology. 2009 Nov;297(5):H1617-28. Epub 2009 Aug 28 |
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Detectability of small blood vessels with high-frequency power Doppler and selection of wall filter cut-off velocity for microvascular imaging
Stephen Z. Pinter, James C. Lacefield Ultrasound in Medicine & Biology. 2009 Jul;35(7):1217-28. Epub 2009 Apr 25 |
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Intravascular Ultrasound (IVUS): A Potential Arthroscopic Tool for Quantitative Assessment of Articular Cartilage
Yan-Ping Huang1 and Yong-Ping Zheng1,2 The open biomedical engineering journal. 2009 Jun 26;3:13-20 |
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S100A12 Mediates Aortic Wall Remodeling and Aortic Aneurysm
Marion Hofmann Bowman, Jeannine Wilk, Ahlke Heydemann, Gene Kim, Jalees Rehman, Joseph A. Lodato, Jai Raman, Elizabeth M. McNally Circulation Research. 2010 Jan 8;106(1):145-54. Epub 2009 Oct 29 |
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Ultrasound and Doppler micro-imaging in a model of rheumatoid arthritis in mice
Gaëlle Clavel 1, Carmen Marchiol-Founigault 2, Gilles Renault 2, Marie-Christophe Boissier 2, Didier Fradelizi 2 and Natacha Bessis 2* Annals of the Rheumatic Diseases. 2008 Dec; 67: 1765 - 1772 |
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In vitro and in vivo evidence for shear-induced activation of latent transforming growth factor-{beta}1
Ahamed J, Burg N, Yoshinaga K, Janczak CA, Rifkin DB, Coller BS. Blood. 2008 Nov 1;112(9):3650-60. |
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Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice
Murphy PA, Lam MT, Wu X, Kim TN, Vartanian SM, Bollen AW, Carlson TR, Wang RA Proceedings of the National Academy of Sciences. 2008 Aug 5;105(31):10901-6. |
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Fetal growth restriction triggered by polycyclic aromatic hydrocarbons is associated with altered placental vasculature and AhR-dependent changes in cell death
Detmar J, Rennie MY, Whiteley KJ, Qu D, Taniuchi Y, Shang X, Casper RF, Adamson SL, Sled JG, Jurisicova A. American Journal of Physiology, Endocrinology and Metabolism. 2008 Aug;295(2):E519-30. |
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Noninvasive real-time imaging of intima thickness after rat carotid artery balloon injury using ultrasound biomicroscopy
Razuvaev A, Lund K, Roy J, Hedin U, Caidahl K. Atherosclerosis. 2008 Aug;199(2):310-6. |
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Increased shear rate resistance and fastest kinetics of erythrocyte aggregation in diabetes measured with ultrasound
Guy Cloutier, Audrey Zimmer, François T.H. Yu, and Jean-Louis Chiasson Diabetes Care. 2008 Jul;31(7):1400-2 |
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Rgs5 targeting leads to chronic low blood pressure and a lean body habitus
Hyeseon Cho,Chung Park, Il-Young Hwang,Sang-Bae Han, Dan Schimel, Daryl Despres, and John H. Kehrl Molecular and Cellular Biology. 2008 April;28(8): 2590-2597. |
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Urocortin2 inhibits tumor growth via effects on vascularization and cell proliferation
Zhengrong Hao, Yan Huang, Jake Cleman, Ion S. Jovin, Wylie W. Vale, Tracy L. Bale, and Frank J. Giordano Proceedings of the National Academy of Sciences. 2008 March 11;105(10): 3939-3944 |
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Micro-ultrasound imaging assessment of carotid plaque characteristics in apolipoprotein-E knockout mice
Ni M, Zhang M, Ding SF, Chen WQ, Zhang Y. Atherosclerosis. 2008 Mar;197(1):64-71. Epub 2007 Sep 17 |
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Innovations in imaging for chronic total occlusions: a glimpse into the future of angiography's blind-spot
Brian K. Courtney, Nigel R. Munce, Kevan J. Anderson, Amandeep S. Thind, General Leung, Perry E. Radau, F. Stuart Foster, I. Alex Vitkin, Robert S. Schwartz, Alexander J. Dick, Graham A. Wright and Bradley H. Strauss European Heart Journal. 2008 Mar;29(5):583-93 |
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{alpha}2{beta}1 integrin expression in the tumor microenvironment enhances tumor angiogenesis in a tumor cell-specific manner
Zhang Z, Ramirez NE, Yankeelov TE, Li Z, Ford LE, Qi Y, Pozzi A, Zutter MM Blood. 2008 Feb 15;111(4):1980-8. |
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3D-Micro-Ultrasound Documents Diltiazem Mediated Changes in Central Aortic Hemodynamics
Michelle M Bunzel, Barry Campbell, Karim Azer, Christopher Tong, Sharmilee Ramcharan, Kavita Saini, Craig Fancourt, Shubing Wang and Matthew Walker Journal of the Federation of American Societies for Experimental Biology. 2008 Feb; 22:587.2 |
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In Vivo Measurement of Flow-Mediated Vasodilation in Living Rats using High-Resolution Ultrasound
Christian Heiss1, Richard E. Sievers2, Nicolas Amabile1, Tony Y Momma3, Qiumei Chen2, Shobha Natarajan1, Yerem Yeghiazarians1, and Matthew L. Springer1* Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H1086-93. Epub 2007 Nov 30 |
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Proteasome inhibition promotes regression of left ventricular hypertrophy
William E. Stansfield1, Ruhang Tang1, Nancy C Moss1, Albert S Baldwin2, Monte S Willis3, and Craig H Selzman1 American Journal of Physiology, Heart and Circulatory Physiology. 2008 Feb;294(2):H645-50. Epub 2007 Nov 21 |
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In vivo measurement of flow-mediated vasodilation in living rats using high-resolution ultrasound
Christian Heiss, Richard E. Sievers, Nicolas Amabile, Tony Y. Momma, Qiumei Chen, Shobha Natarajan, Yerem Yeghiazarians, and Matthew L. Springer American Journal of Physiology, Heart and Circulatory Physiology2008 Feb;294(2):H1086-93. Epub 2007 Nov 30 |
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The netrin receptor UNC5B promotes angiogenesis in specific vascular beds
Navankasattusas S, Whitehead KJ, Suli A, Sorensen LK, Lim AH, Zhao J, Park KW, Wythe JD, Thomas KR, Chien CB, Li DY Development. 2008 Feb;135(4):659-67. |
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Uterine vascular function in a transgenic preeclampsia rat model
Verlohren S, Niehoff M, Hering L, Geusens N, Herse F, Tintu AN, Plagemann A, LeNoble F, Pijnenborg R, Muller DN, Luft FC, Dudenhausen JW, Gollasch M, Dechend R. Hypertension. 2008 Feb;51(2):547-53. |
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Secoisolariciresinol diglucoside induces neovascularization-mediated cardioprotection against ischemia–reperfusion injury in hypercholesterolemic myocardium
Suresh Varma Penumathsa, Srikanth Koneru, Lijun Zhan, Saji John, Venogopal P. Menon , Kailash Prasad, Nilanjana Maulik J Mol Cell Cardiol.2008 Jan;44(1):170-9. Epub 2007 Oct 4 |
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Inhibition of N-Ethylmaleimide-Sensitive Factor Protects Against Myocardial Ischemia/Reperfusion Injury
John W. Calvert, Susheel Gundewar, Munekazu Yamakuchi, Pierce C. Park, William M. Baldwin III, David J. Lefer, Charles J. Lowenstein Circ Res. 2007 Dec 7;101(12):1247-54; Epub 2007 Oct 11 |
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CD36 Expression Contributes to Age-Induced Cardiomyopathy in Mice
Koonen DP, Febbraio M, Bonnet S, Nagendran J, Young ME, Michelakis ED, Dyck JR. Circulation. 2007 Nov 6;116(19):2139-47. Epub 2007 Oct 22. |
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Pulsed-high intensity focused ultrasound enhanced tPA mediated thrombolysis in a novel in vivo clot model, a pilot study
Michael J. Stone a,d, Victor Frenkel a, Sergio Dromi a, Peter Thomas b, Ryan P. Lewis a, King C.P. Li a, McDonald Horne III c, Bradford J. Wood a Thrombosis Research2007 Nov;121(2):193-202. Epub 2007 May 4 |
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Sensitive ultrasonic delineation of steroid treatment in living dystrophic mice with energy-based and entropy-based radio frequency signal processing
Wallace KD, Marsh JN, Baldwin SL, Connolly AM, Keeling R, Lanza GM, Wickline SA, Hughes MS. IEEE Trans Ultrason Ferroelectr Freq Control. 2007 Nov;54(11):2291-9. |
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Measurements of Aneurysm Morphology Determined by 3-D Micro-Ultrasound Imaging as Potential Quantitative Biomarkers in a Mouse Aneurysm Model
Alyse Goldberg, Pria Pakkiri, Erbin Dai, Alexandra Lucas and Aaron Fenster Ultrasound Med Biol.2007 Oct;33(10):1552-60 |
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Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway
Gökhan M. Mutlu1, David Green2, Amy Bellmeyer1, Christina M. Baker1, Zach Burgess1, Nalini Rajamannan3, John W. Christman4, Nancy Foiles2, David W. Kamp1, Andrew J. Ghio5, Navdeep S. Chandel1, David A. Dean1, Jacob I. Sznajder1 and G.R. Scott Budinger J. Clin. Invest. 2007 Oct;117(10):2952-61 |
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Cardiac Specific Haploin sufficiency of ß-Catenin Attenuates Cardiac Hypertrophy But Enhances Fetal Gene Expression in Response to Aortic Constriction
Jiaxiang Qu1, Jibin Zhou1, Xian Ping Yi1,2, Baojun Dong1, Hanqiao Zheng1, Lisa M. Miller1, Xuejun Wang1, Michael D. Schneider4, Faqian Li1 Journal of Molecular and Cellular Cardiology. 2007 Sept; 43(3): 319-326; Epub 2007 Jun 21 |
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Noninvasive Ultrasonic Measurement Of Regional And Local Pulse-Wave Velocity In Mice
Ross Williams, Andrew Needles, Emmanuel Cherin, Yu-Qing Zhou, R. Mark Henkelman, S. Lee Adamson, And F. Stuart Foster Ultrasound in Med. & Biol. 2007 Sep;33(9):1368-75. Epub 2007 Jun 11 |
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Molecular Imaging of Inflammation in Atherosclerosis With Targeted Ultrasound Detection of Vascular Cell Adhesion Molecule-1
Beat A. Kaufmann, MD; John M. Sanders, BS; Christopher Davis, MD; Aris Xie, MS; Patrick Aldred, MS; Ian J. Sarembock, MB, ChB; Jonathan R. Lindner, MD Circulation. 2007 Jul 17;116(3):276-84. Epub 2007 Jun 25 |
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Morphological differences between guinea pig aortic and venous endothelial cells in situ
Kazuo Katoh, Yumiko Kano, Shigeo Ookawara Cell Biology International. 2007 Jun;31(6):554-64. Epub 2006 Dec 3 |
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Transitions in Early Embryonic Atrioventricular Valvular Function Correspond With Changes in Cushion Biomechanics That Are Predictable by Tissue Composition
Jonathan T. Butcher, Tim C. McQuinn, David Sedmera, Debi Turner, Roger R. Markwald Circulation Research. 2007 May 25;100(10):1503-11. Epub 2007 May 3 |
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Pulse doppler and M-mode to assess viability of cardiac allografts using heterotopic femoral heart transplantation in rats
Gordon CR, Lefebvre DR, Matthews MS, Strande LF, Marra SW, Guglielmi M, Skaf J, Hollenberg SM, Hewitt CW. Microsurgery. 2007 May 9; 27(4):240-4 |
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Reconsidering the Layer Thickness Distribution in Aortic Valve Cusps Using High-Frequency Ultrasound
Zamir Khan1,2, Derek R. Boughner1,2,3, and James C. Lacefield1,2 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro. 2007 April 12-15; PP. 868 - 871 |
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Characterization of circulatory disorders in {beta}-thalassemic mice by noninvasive ultrasound biomicroscopy
Stoyanova E, Trudel M, Felfly H, Garcia D, Cloutier G. Physiol Genomics. 2007 Mar 14;29(1):84-90. Epub 2006 Nov 28 |
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Increasing Peripheral Artery Intima Thickness From Childhood to Seniority
Osika W, Dangardt F, Gronros J, Lundstam U, Myredal A, Johansson M, Volkmann R, Gustavsson T, Gan LM, Friberg P Arteriosclerosis, Thrombosis, and Vascular Biology. 2007 Mar;27(3):671-6. Epub 2006 Dec 28 |
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Non-invasive real-time imaging of atherosclerosis in mice using ultrasound biomicroscopy
Gan LM, Gronros J, Hagg U, Wikstrom J, Theodoropoulos C, Friberg P, Fritsche-Danielson R. Atherosclerosis. 2007 Feb;190(2):313-20. Epub 2006 May 4 |
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Hemodynamics in the Mouse Aortic Arch as Assessed by MRI, Ultrasound and, Numerical Modeling
Feintuch A, Ruengsakulrach P, Lin A, Zhang J, Zhou Y, Bishop J, Davidson L, Courtman D, Foster FS, Steinman D, Henkelman RM, Ethier CR. Am J Physiol Heart Circ Physiol. 2007 Feb;292(2):H884-92. Epub 2006 Sep 29 |
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Pulse Wave Imaging in Murine Abdominal Aortas
Kana Fujikura,Jianwen Luo, Mathieu Pernot, Royd Fukumoto*, David Tilson III* and Elisa E. Konofagou Ultrasonics Symposium 2006 IEEE. 2006 Oct 2-6; PP. 868-871 |
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Rapid dilation of the abdominal aorta during infusion of angiotensin II detected by noninvasive high-frequency ultrasonography
Barisione C, Charnigo R, Howatt DA, Moorleghen JJ, Rateri DL, Daugherty A. J Vasc Surg. 2006 Aug;44(2):372-6 |
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Transgenic expression of Angiopoietin 1 in the liver leads to changes in lymphatic and blood vessel architecture
Haninec AL, Voskas D, Needles A, Brown AS, Stuart Foster F, Dumont DJ. Biochem Biophys Res Commun. 2006 Jul 14;345(4):1299-1307. Epub 2006 May 4 |
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Ultrahigh frame rate retrospective ultrasound microimaging and blood flow visualization in mice in vivo.
Emmanuel Chérin, Ross Williams, Andrew Needles, Godwin Liu, Christopher White, Allison S. Brown, Yu-Qing Zhou and F. Stuart Foster Ultrasound in Medicine & Biology. 2006 May; Vol 32, Issue 5, PP. 683-691 |
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Proximal to Middle Left Coronary Artery Flow Velocity Ratio, As Assessed Using Color Doppler Echocardiography, Predicts Coronary Artery Atherosclerosis in Mice
Julia Gro¨nros, Johannes Wikstro¨m, Ulrika Ha¨gg, Birger Wandt, Li-ming Gan Arterioscler Thromb Vasc Biol. 2006 May;26(5):1126-31. Epub 2006 Mar 2 |
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Evaluation of an Algorithm for Semiautomated Segmentation of Thin Tissue Layers in High-Frequency Ultrasound Images
Qiang Qiu, Joy Dunmore-Buyze, Derek R. Boughner, and James C. Lacefield IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 2006 Feb;vol.53, no.2, pg 324-34 |
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Functional and Morphologic Imaging of Coronary Atherosclerosis in Living Mice Using High-Resolution Color Doppler Echocardiography and Ultrasound Biomicroscopy
Johannes Wikström, MSc*, Julia Grönros, MSc*, Göran Bergström, MD, PhD and Li-ming Gan, MD, PhD J Am Coll Cardiol;2005 Aug 16;46(4):720-727; Published online 27 July 2005 |
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Gene expression profile and aortic vessel distensibility in voluntarily exercised spontaneously hypertensive rats: potential role of heat shock proteins
Hagg U, Johansson ME, Gronros J, Naylor AS, Jonsdottir IH, Bergstrom G, Svensson PA, Gan LM. Physiol Genomics. 2005 Aug 11;22(3):319-26. Epub 2005 May 24 |
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Introducing the German Mouse Clinic: open access platform for standardized phenotyping
Gailus-Durner V, Fuchs H, Becker L, Bolle I, Brielmeier M, Calzada-Wack J, Elvert R, Ehrhardt N, Dalke C, Franz TJ, Grundner-Culemann E, Hammelbacher S, Holter SM, Holzlwimmer G, Horsch M, Javaheri A, Kalaydjiev SV, Klempt M, Kling E, Kunder S, Lengger C, Lisse T, Mijalski T, Naton B, Pedersen V, Prehn C, Przemeck G, Racz I, Reinhard C, Reitmeir P, Schneider I, Schrewe A, Steinkamp R, Zybill C, Adamski J, Beckers J, Behrendt H, Favor J, Graw J, Heldmaier G, Hofler H, Ivandic B, Katus H, Kirchhof P, Klingenspor M, Klopstock T, Lengeling A, Muller W, Ohl F, Ollert M, Quintanilla-Martinez L, Schmidt J, Schulz H, Wolf E, Wurst W, Zimmer A, Busch DH, de Angelis MH. Nat Methods. 2005 Jun;2(6):403-4. |
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Noninvasive measurement of abdominal aortic aneurysms in intact mice by a high-frequency ultrasound imaging system
Martin-McNulty B, Vincelette J, Vergona R, Sullivan ME, Wang YX. Ultrasound Med Biol. 2005 Jun;31(6):745-9. |
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Non-invasive high-frequency vascular ultrasound elastography
Maurice RL, Daronat M, Ohayon J, Stoyanova E, Foster FS, Cloutier G. Phys Med Biol. 2005 Apr 7;50(7):1611-28. Epub 2005 Mar 22. |
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Three-dimensional visualization and thickness estimation of aortic valve cusps using high-frequency ultrasound
James C Lacefield, Jeff Weaver1, Jack R Spence3, Joy Dunmore-Buyze3 and Derek R Boughner2,3,4 Physiological Measurement. 2004 Feb;(25) 2004: 27-36 |
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Maternal cardiovascular changes during pregnancy and postpartum in mice
Alan Y. H. Wong1,2,3, Shathiyah Kulandavelu1,2,3, Kathie J. Whiteley1, Dawei Qu1, B. Lowell Langille1,2,4, and S. Lee Adamson1,2,3 American journal of physiology. Heart and circulatory physiology. 2002 Mar; 282: H918-H925 |
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Applications - Embryonic Cardiology
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Novel Genetic Approach for In Vivo Vascular Imaging in Mice
Benjamin B. Bartelle, César A. BerrÃos-Otero, Joe J. Rodriguez, Anne E. Friedland, Orlando Aristizábal, Daniel H. Turnbull Circulation Research. 2012 Mar 30;110(7):938-47. Epub 2012 Feb 28 |
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Ablation of Nkx2-5 at mid-embryonic stage results in premature lethality and cardiac malformation
Ryota Terada1, Sonisha Warren1, Jonathan T. Lu2, Kenneth R. Chien3, Andy Wessels4 and Hideko Kasahara1 Cardiovascular Research. 2011 Mar 8. [Epub ahead of print] |
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Regulation of Placental Growth by Aldosterone and Cortisol
Carine Gennari-Moser, Eliyahu V. Khankin, Simone Schüller, Geneviève Escher, Brigitte M. Frey, C.-Bettina Portmann, Marc U. Baumann, Andrea D. Lehmann, Daniel Surbek, S. Ananth Karumanchi, Felix J. Frey, and Markus G. Mohaup Endocrinology.2010 Nov 10. [Epub ahead of print] |
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Using Ultrasonography to Define Fetal-Maternal Relationships: Moving from Humans to Mice
Zhang, Jianhong; Croy, B Anne Comparative Medicine. 2009 Dec;59(6):527-33 |
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Outflow tract cushions perform a critical valve-like function in the early embryonic heart requiring BMPRIA-mediated signaling in cardiac neural crest
Aya Nomura-Kitabayashi1, Colin K.L. Phoon2, Satoshi Kishigami1, Julie Rosenthal3, Yasutaka Yamauchi4, Kuniya Abe4, Ken-ichi Yamamura4, Rajeev Samtani3, Cecilia W. Lo5, and Yuji Mishina6 American Journal of Physiology, Heart and Circulatory Physiology. 2009 Nov;297(5):H1617-28. Epub 2009 Aug 28 |
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Lmo4 and Clim1 Progressively Delineate Cortical Projection Neuron Subtypes during Development
Eiman Azim1,2,3, Sara J. Shnider1,2,3,4, Gustav Y. Cederquist1,2,3, U. Shivraj Sohur1,2,3 and Jeffrey D. Macklis1,2,3 Cerebral Cortex. 2009 Jul;19 Suppl 1:i62-9. Epub 2009 Apr 14 |
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In vivo virtual histology of mouse embryogenesis by ultrasound biomicroscopy and magnetic resonance imaging
P. Pallares 1 , M. E. Fernandez-Valle 2 and A. Gonzalez-Bulnes 3 Reproduction, Fertility and Development. 2009;21(2):283-92 |
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Fetal growth restriction triggered by polycyclic aromatic hydrocarbons is associated with altered placental vasculature and AhR-dependent changes in cell death
Detmar J, Rennie MY, Whiteley KJ, Qu D, Taniuchi Y, Shang X, Casper RF, Adamson SL, Sled JG, Jurisicova A. American Journal of Physiology, Endocrinology and Metabolism. 2008 Aug;295(2):E519-30. |
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Mouse heart valve structure and function: echocardiographic and morphometric analyses from the fetus through the aged adult
Robert B. Hinton, Jr., Christina M. Alfieri, Sandra A. Witt, Betty J. Glascock, Philip R. Khoury, D. Woodrow Benson, and Katherine E. Yutzey American Journal of Physiology, Heart and Circulatory Physiology. 2008 April 4;294: H2480-H2488 |
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Modest maternal caffeine exposure affects developing embryonic cardiovascular function and growth
Momoi N, Tinney JP, Liu LJ, Elshershari H, Hoffmann PJ, Ralphe JC, Keller BB, Tobita K American Journal of Physiology, Heart and Circulatory Physiology. 2008 May;294(5):H2248-56. |
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The netrin receptor UNC5B promotes angiogenesis in specific vascular beds
Navankasattusas S, Whitehead KJ, Suli A, Sorensen LK, Lim AH, Zhao J, Park KW, Wythe JD, Thomas KR, Chien CB, Li DY Development. 2008 Feb;135(4):659-67. |
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Uterine vascular function in a transgenic preeclampsia rat model
Verlohren S, Niehoff M, Hering L, Geusens N, Herse F, Tintu AN, Plagemann A, LeNoble F, Pijnenborg R, Muller DN, Luft FC, Dudenhausen JW, Gollasch M, Dechend R. Hypertension. 2008 Feb;51(2):547-53. |
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High-frequency ultrasonographic imaging of avian cardiovascular development
Tim C. McQuinn1 2Momka Bratoeva1, Angela DeAlmeida1, Mathieu Remond1, Robert P. Thompson1, David Sedmera1 3 4 Developmental Dynamics2007 Dec;236(12):3503-13 |
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Enhancing Repair of the Mammalian Heart
Maria Paola Santini, Lana Tsao, Laurent Monassier, Catherine Theodoropoulos, Janice Carter, Enrique Lara-Pezzi, Esfir Slonimsky, Ekaterina Salimova, Patrice Delafontaine, Yao-Hua Song, Martin Bergmann, Christian Freund, Ken Suzuki, and Nadia Rosenthal Circ. Res.2007 Jun 22;100(12):1732-40. Epub 2007 May 24 |
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Transitions in Early Embryonic Atrioventricular Valvular Function Correspond With Changes in Cushion Biomechanics That Are Predictable by Tissue Composition
Jonathan T. Butcher, Tim C. McQuinn, David Sedmera, Debi Turner, Roger R. Markwald Circulation Research. 2007 May 25;100(10):1503-11. Epub 2007 May 3 |
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Fgl2 deficiency causes neonatal death and cardiac dysfunction during embryonic and postnatal development in mice
Junwu Mu, Dawei Qu, Agata Bartczak, M. James Phillips, Justin Manuel, Wei He, Cheryl Koscik, Michael Mendicino, Li Zhang, David A. Clark, David R. Grant, Peter H. Backx, Gary A. Levy, and S. Lee Adamson Physiol. Genomics. 2007 Sept; 31(1): 53-62, Epub 2007 Jun 5 |
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Increased Ventricular Preload Is Compensated by Myocyte Proliferation in Normal and Hypoplastic Fetal Chick Left Ventricle
deAlmeida A, McQuinn T, Sedmera D. Circulation Research. 2007 May 11; Circ. Res. 2007 100: 1246-1248; Epub 2007 Apr 5 |
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Cardiovascular Developmental Insights from Embryos
BRADLEY B. KELLER, LI J. LIU, JOSEPH P. TINNEY AND KIMIMASA TOBITA Ann N Y Acad Sci. 2007 Apr;1101:377-88. Epub 2007 Feb 15. |
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Techniques et applications de l’échographie haute résolution non invasive (Techniques and applications of non-invasive high-resolution ultrasound imaging)
J-M Grégoire, S Serrière, G Georgesco, F Jamet, A Bleuzen, F Ossant, F Levassort, F Tranquart, F Patat Éditions Françaises de Radiologie, 2006 Dec; Vol 87 - N° 12-C2 |
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[High-resolution ultrasound imaging of the mouse]
G Renault, P Bonnin, C Marchiol-Fournigault, JM Gregoire, S Serrière, B Richard, D Fradelizi Éditions Françaises de Radiologie. 2006 Dec; Vol 87 - N° 12-C2 |
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Fetal mouse imaging using echocardiography: a review of current technology
Spurney CF, Lo CW, Leatherbury L. Echocardiography. 2006 Nov;23(10):891-9 |
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Developmental changes in hemodynamics of uterine artery, utero- and umbilicoplacental, and vitelline circulations in mouse throughout gestation
Junwu Mu1,2,3 and S. Lee Adamson1,2,3 American journal of physiology. Heart and circulatory physiology. 2006 Sep;291(3):H1421-8. Epub 2006 Apr 7 |
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Imaging Tools for the Developmental Biologist: Ultrasound Biomicroscopy of Mouse Embryonic Development
Phoon CK. Pediatric Research. 2006 Jul;60(1):14-21. Epub 2006 May 11 |
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Cardiovascular Function in Mice During Normal Pregnancy and in the Absence of Endothelial NO Synthase
Kulandavelu S, Qu D, Adamson SL. Hypertension. 2006 Jun;47(6):1175-82. Epub 2006 Apr 24 |
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Embryonic and Neonatal Phenotyping of Genetically Engineered Mice
Shathiyah Kulandavelu, Dawei Qu, Nana Sunn, Junwu Mu, Monique Y. Rennie, Kathie J. Whiteley, Johnathon R. Walls, Nicholas A. Bock, John C. H. Sun, Andrea Covelli, John G. Sled, and S. Lee Adamson ILAR Journal, 2006 Mar; 47(2):103-17 |
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High resolution ultrasound-guided microinjection for interventional studies of early embryonic and placental development in vivo in mice
John C. Slevin, Lois Byers, Marina Gertsenstein, Dawei Qu, Junwu Mu, Nana Sunn, John C.P. Kingdom, Janet Rossant and S. Lee Adamson BMC Developmental Biology,2006 Feb 27; 6:10 |
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Noninvasive Localization of Nuclear Factor of Activated T Cells c1-/- Mouse Embryos by Ultrasound Biomicroscopy-Doppler Allows Genotype-phenotype Correlation
Ji RP, Phoon CK. J Am Soc Echocardiogr. 2005 Dec;18(12):1415-21 |
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Developmental structure-function insights from Tbx5del/+ mouse model of Holt-Oram syndrome
Keller, BB. Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H975-6. |
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Arterial hemodynamics and mechanical properties after circulatory intervention in the chick embryo
Tang YD, Kuzman JA, Said S, Anderson BE, Wang X, Gerdes AM. Circulation. 2005 May;208(Pt 10):1877-85 |
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Current mouse models for studying cardiac dysfunctions: technical and imaging aspects
Laurent Monassier*, Catherine Theodoropoulos**, Andre Constantinesco*** Drug Discovery Today: Disease Models. 2004 Dec 17; Vol 1, Issue 3, PP 235-241 |
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Baf60c is essential for function of BAF chromatin remodelling complexes in heart development
HEIKO LICKERT, JUN K. TAKEUCHI, INGO VON BOTH, JOHNATHON R. WALLS, FIONNUALA MCAULIFFE, S. LEE ADAMSON, R. MARK HENKELMAN, JEFFREY L. WRAN, JANET ROSSANT & BENOIT G. BRUNEAU Nature2004 Nov 4;432(7013):107-12 |
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Biological effects of high-frequency ultrasound exposure during mouse organogenesis
Allison S. Brown*, Angela D. Reid*, Lisa Leamen*, Viviene Cucevic* and F. Stuart Foster*, † Ultrasound Med Biol. 2004 Sep;30(9):1223-32 |
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Developmental changes in left and right ventricular diastolic filling patterns in mice
Yu-Qing Zhou1, F. Stuart Foster2, Robert Parkes3, and S. Lee Adamson4 American Journal of Physiology. Heart and Circulatory Physiology. 2003 Oct;285(4):H1563-75. Epub 2003 Jun 12 |
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40-MHZ echocardiography scanner for cardiovascular assessment of mouse embryos
Aristizabal O, Christopher DA, Foster FS, Turnbull DH. Ultrasound Med Biol. 1998 Nov;24(9):1407-17. |
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Applications - Dermatological Imaging
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Applications - Ocular Imaging
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In Vivo High-Frequency, Contrast-Enhanced Ultrasonography of Uveal Melanoma in Mice: Imaging Features and Histopathologic Correlations
Qing Zhang1,2,3, Hua Yang1,3, Shin J. Kang1, Yanggan Wang4, Geoffrey D. Wang5, Tonya Coulthard6 and Hans E. Grossniklaus1,7 Investigative Ophthalmology and Visual Science. 2011 Jan 18. [Epub ahead of print] |
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Matrix Metalloproteinase 2 and 9 Dysfunction Underlie Vascular Stiffness in Circadian Clock Mutant Mice
Ciprian B. Anea; M. Irfan Ali; Jessica M. Osmond; Jennifer C. Sullivan; David W. Stepp; Ana M. Merloiu; R. Daniel Rudic Arteriosclerosis, Thrombosis, and Vascular Biology2010 Dec;30(12):2535-43. Epub 2010 Sep 9 |
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Blood velocity measurement in the posterior segment of the rabbit eye using combined spectral Doppler and power Doppler ultrasound
Walid Abdallah1, Amani Fawzi1,2, Hitenkumar Patel3, Grant Dagliyan3, Naoki Matsuoka1, Edward Grant4 and Mark Humayun1, 2, 5, 6 Graefe's Archive for Clinical and Experimental Opthalmology. 2010 Jan;248(1):93-101. Epub 2009 Oct 3 |
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Ultrasound-guided in utero injections allow studies of the development and function of the eye
Claudio Punzo and Constance L. Cepko Developmental dynamics. 2008 Apr;237(4):1034-42 |
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Measurement of Human Choroidal Melanoma Xenograft Volume in Rats Using High-Frequency Ultrasound
Rod D. Braun and Kerry S. Vistisen Investigative Ophthalmology and Visual Science. 2008 Jan;49(1):16-22 |
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Quantitation of Hemodynamic Function during Developmental Vascular Regression in the Mouse Eye
Brown AS, Leamen L, Cucevic V, Foster FS Invest Ophthalmol Vis Sci. 2005 Jul;46(7):2231-7. |
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Thermal assessment of 40-MHz pulsed Doppler ultrasound in human eye
Cucevic V, Brown AS, Foster FS. Ultrasound in medicine & biology. 2005 Apr;31(4):565-73 |
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In Vivo Assessment of Postnatal Murine Ocular Development by Ultrasound Biomicroscopy
Allison S. Brown A1, MingYu Zhang A1, Viviene Cucevic A1, Charles J. Pavlin A2, F. Stuart Foster A3 Current Eye Research, 2005 Jan;30(1):45-51 |
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In vivo imaging of embryonic development in the mouse eye by ultrasound biomicroscopy
Foster FS, Zhang M, Duckett AS, Cucevic V, Pavlin CJ. Investigative Ophthalmology & Visual Science. 2003 Jun;44(6):2361-6. |
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Applications - Abdominal Imaging
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Trimodal Gadolinium-Gold Microcapsules Containing Pancreatic Islet Cells Restore Normoglycemia in Diabetic Mice and Can Be Tracked by Using US, CT, and Positive-Contrast MR Imaging
Dian R. Arifin, PhD, Christopher M. Long, PhD, Assaf A. Gilad, PhD, Christophe Alric, PhD, Stéphane Roux, PhD, Olivier Tillement, PhD, Thomas W. Link, MS, Aravind Arepally, MD and Jeff W. M. Bulte, PhD Radiology.2011 Jul 6. [Epub ahead of print] |
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miR669a and miR669q prevent skeletal muscle differentiation in postnatal cardiac progenitors
Stefania Crippa1, Marco Cassano1, Graziella Messina3,4, Daniela Galli5, Beatriz G. Galvez6, Tomaz Curk7, Claudia Altomare8, Flavio Ronzoni5, Jaan Toelen2, Rik Gijsbers2, Zeger Debyser2, Stefan Janssens9, Blaz Zupan7, Antonio Zaza8, Giulio Cossu3,4, and Maurilio Sampaolesi1,5 The Journal of Cell Biology. 2011 Jun 27;193(7):1197-212. |
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Quantitative Estimates of the Variability of In Vivo Sonographic Measurements of the Mouse Aorta for Studies of Abdominal Aortic Aneurysms and Related Arterial Diseases
Uchechukwu K. Sampson, MBBS, MBA, MPH, MSc(Oxon)?, Prudhvidhar R. Perati, MSc, Petra A. Prins, MSc, Wellington Pham, PhD, Zhouwen Liu, MS, Frank E. Harrell Jr, PhD, MacRae F. Linton, MD, John C. Gore, PhD, Valentina Kon, MD and Sergio Fazio, MD, PhD Journal of Ultrasound in Medicine. 2011 Jun; vol.30, no.6, pp 773-784 |
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Assessing vesicoureteral reflux in live inbred mice via ultrasound with a microbubble contrast agent
Jose Paredes1, Sunder Sims-Lucas1, Hang Wang2, Weining Lu2, Brian Coley3, George K. Gittes1,4, and Carlton M. Bates1,5 American Journal of Physiology. Renal Physiology. 2011 May;300(5):F1262-5. Epub 2011 Feb 16 |
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Preclinical Models for Neuroblastoma: Establishing a Baseline for Treatment
Tal Teitz1, Jennifer J. Stanke1,2, Sara Federico2,3, Cori L. Bradley2, Rachel Brennan2, Jiakun Zhang2, Melissa D. Johnson4, Jan Sedlacik5, Madoka Inoue1, Ziwei M. Zhang4, Sharon Frase6, Jerold E. Rehg7, Claudia M. Hillenbrand5, David Finkelstein8, Christopher Calabrese4, Michael A. Dyer2,9,10, Jill M. Lahti1,11 PLoS One. 2011 Apr 29;6(4):e19133 |
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Non- invasive in vivo analysis of a murine aortic graft using high resolution ultrasound microimaging
Rowinska Z, Zander S, Zernecke A, Jacobs M, Langer S, Weber C, Merx MW, Koeppel TA European Journal of Radiology. 2011 Feb 17. [Epub ahead of print] |
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Telomerase Deficiency in Bone Marrow–Derived Cells Attenuates Angiotensin II–Induced Abdominal Aortic Aneurysm Formation
Hannes M. Findeisen; Florence Gizard; Yue Zhao; Dianne Cohn; Elizabeth B. Heywood; Karrie L. Jones; David H. Lovett; Deborah A. Howatt; Alan Daugherty; Dennis Bruemmer Arteriosclerosis, Thrombosis and Vascular Biology. 2011 Feb;31(2):253-60. Epub 2010 Nov 18 |
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Influences of Aortic Motion and Curvature on Vessel Expansion in Murine Experimental Aneurysms
Craig J. Goergen; Junya Azuma; Kyla N. Barr; Lars Magdefessel; Dara Y. Kallop; Alvin Gogineni; Amarjeet Grewall; Robby M. Weimer; Andrew J. Connolly; Ronald L. Dalman; Charles A. Taylor; Philip S. Tsao; Joan M. Greve Arteriosclerosis, Thrombosis and Vascular Biology. 2011 Feb;31(2):270-9. Epub 2010 Nov 11 |
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Spontaneous Pregnancy Loss Mediated by Abnormal Maternal Inflammation in Rats Is Linked to Deficient Uteroplacental Perfusion
Stephen J. Renaud, Tiziana Cotechini, Jill S. Quirt, Shannyn K. Macdonald-Goodfellow, Maha Othman and Charles H. Graham The Journal of Immunology. 2011 Feb 1;186(3):1799-808. Epub 2010 Dec 27 |
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Chronic Uremia Stimulates LDL Carbamylation and Atherosclerosis
Eugene O. Apostolov1,2, Debarti Ray1, Alena V. Savenka1, Sudhir V. Shah2,3 and Alexei G. Basnakian1,2,3 Journal of the American Society of Nephrology. 2010 Nov;21(11):1852-7. Epub 2010 Oct 14 |
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Enhanced Abdominal Aortic Aneurysm Formation in Thrombin-Activatable Procarboxypeptidase B–Deficient Mice
Geoffrey Schultz ; Maureen Tedesco ; Eiketsu Sho ; Toshihiko Nishimura ; Shadi Sharif ; Xiaoyan Du ; Timothy Myles ; John Morser ; Ronald L. Dalman ; and Lawrence L.K. Leung Arteriosclerosis, Thrombosis, and Vascular Biology. 2010 Jul;30(7):1363-70. Epub 2010 Apr 29 |
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Effect of microbubble size on fundamental mode high frequency ultrasound imaging in mice
Shashank Sirsi1, Jameel Feshitan1, James Kwan1, Shunichi Homma2 and Mark Borden1 Ultrasound in Medicine & Biology. 2010 Jun;36(6):935-48. Epub 2010 May 5 |
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High-Resolution Ultrasound Imaging. A Novel Technique for the Noninvasive in Vivo Analysis of Endometriotic Lesion and Cyst Formation in Small Animal Models
Matthias W. Laschke1, Christina K�rbel1, Jeannette Rudzitis-Auth1, Isabella Gashaw2, Michael Reinhardt2, Peter Hauff2, Thomas M. Zollner2, and Michael D. Menger1 The American Journal of Pathology. 2010 [Epub ahead of print] 2009 Dec 30. |
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Effects of Increased Renal Tubular Vascular Endothelial Growth Factor (VEGF) on Fibrosis, Cyst Formation, and Glomerular Disease
Samy Hakroush1, Marcus J. Moeller2, Franziska Theilig3, Brigitte Kaissling4, Tjeerd P. Sijmonsma5, Manfred Jugold6, Ann L. Akeson7, Milena Traykova-Brauch5, Hiltraud Hosser1, Brunhilde Hähnel1, Hermann-Josef Gröne5, Robert Koesters8 and Wilhelm Kriz1 The American Journal of Pathology. 2009 Nov;175(5):1883-95. Epub 2009 Oct 15 |
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Novel Use of Ultrasound to Examine Regional Blood Flow in the Mouse Kidney
Jennifer C. Sullivan1, Bin Wang1, Erika I Boesen1, Gerard D'Angelo2, Jennifer S. Pollock1, and David M. Pollock1 American Journal of Physiology, Renal Physiology. 2009 Jul;297(1):F228-35. Epub 2009 May 6 |
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Effective prostate cancer chemopreventive intervention with green tea polyphenols in the TRAMP model depends on the stage of the disease
Vaqar Mustafa Adhami, Imtiaz Ahmad Siddiqui, Sami Sarfaraz, Sabih Islam Khwaja, Bilal Bin Hafeez, Nihal Ahmad and Hasan Mukhtar Clinical Cancer Research. 2009 Mar 15;15(6):1947-53. Epub 2009 Mar 10 |
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Real-Time Quantitation of Renal Ischemia Using Targeted Microbubbles: In-vivo Measurement of P-selectin Expression
Sero Andonian, Tonya Coulthard, Arthur D Smith, Pravin S Singhal, and Benjamin R Lee Journal of endourology. 2009 Mar;23(3):373-8 |
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Regulation of Maternal and Fetal Hemodynamics by Heme Oxygenase in Mice
Hui Zhao, Ronald J. Wong, Timothy C. Doyle, Nihar Nayak, Hendrik J. Vreman, Christopher H. Contag, and David K. Stevenson Biology of Reproduction. 2008 Apr;78(4):744-51. Epub 2007 Dec 19 |
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Oncolytic Viral Therapy By Bladder Instillation Using An E1a, E1b Double-Restricted Adenovirus In An Orthotopic Bladder Cancer Model
Hua Wang, Makoto Satoh, Hisashi Abe, Makoto Sunamura, Takuya Moriya, Shigeto Ishidoya, Seiichi Saito, Hirofumi Hamada, And Yoichi Arai Urology, 2006 Sep;68(3):674-81. Epub 2006 Sep 18 |
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Induced Biliary Excretion of Listeria monocytogenes
Jonathan Hardy,1 Jeffrey J. Margolis,2 and Christopher H. Contag1,2,3 Infection and immunity. 2006 Mar;74(3):1819-27 |
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Applications - Reproductive Biology
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Sildenafil Citrate Rescues Fetal Growth in the Catechol-O-Methyl Transferase Knockout Mouse Model
Joanna L. Stanley, Irene J. Andersson, Rajan Poudel, Christian F. Rueda-Clausen, Colin P. Sibley, Sandra T. Davidge, Philip N. Baker Hypertension. 2012 Mar 5. [Epub ahead of print] |
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In vivo imaging of cumulus-oocyte-complexes and small ovarian follicles in cattle using ultrasonic biomicroscopy
L.F.M. Pfeifer1, L.G.B. Siqueira2, G.P. Adams3, R.A. Pierson4, J. Singh3 Animal Reproduction Science. 2012 Mar;131(1-2):88-94. Epub 2012 Mar 7 |
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Spontaneous Pregnancy Loss Mediated by Abnormal Maternal Inflammation in Rats Is Linked to Deficient Uteroplacental Perfusion
Stephen J. Renaud, Tiziana Cotechini, Jill S. Quirt, Shannyn K. Macdonald-Goodfellow, Maha Othman and Charles H. Graham The Journal of Immunology. 2011 Feb 1;186(3):1799-808. Epub 2010 Dec 27 |
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Size and spatial orientation of uterine tissue transplants on the peritoneum crucially determine the growth and cyst formation of endometriosis-like lesions in mice
Christina Körbel, Michael D. Menger and Matthias W. Laschke Human Reproduction. 2010 Oct;25(10):2551-8. Epub 2010 Aug 6 |
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Inhibition of Trophoblast-Induced Spiral Artery Remodeling Reduces Placental Perfusion in Rat Pregnancy
Stefan Verlohren; Nele Geusens; Jude Morton; Iris Verhaegen; Lydia Hering; Florian Herse; Joachim W. Dudenhausen; Dominik N. Muller; Friedrich C. Luft; Judith E. Cartwright; Sandra T. Davidge; Robert Pijnenborg; and Ralf Dechend Hypertension. 2010 Aug;56(2):304-10. Epub 2010 Jul 6 |
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High-Resolution Ultrasound Imaging. A Novel Technique for the Noninvasive in Vivo Analysis of Endometriotic Lesion and Cyst Formation in Small Animal Models
Matthias W. Laschke1, Christina K�rbel1, Jeannette Rudzitis-Auth1, Isabella Gashaw2, Michael Reinhardt2, Peter Hauff2, Thomas M. Zollner2, and Michael D. Menger1 The American Journal of Pathology. 2010 [Epub ahead of print] 2009 Dec 30. |
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Use of ultrasound biomicroscopy to image human ovaries in vitro
Baerwald, A.; Dauk, S.; Kanthan, R.; Singh, J. Ultrasound in Obstetrics & Gynecology. 2009 Aug;34(2):201-7 |
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Ovarian imaging in the mouse using ultrasound biomicroscopy (UBM): a validation study
Carmen N. Mircea 1 , Marla E. Lujan 1 , Rajesh S. Jaiswal 2 , Jaswant Singh 2 , Gregg P. Adams 2 and Roger A. Pierson 1 Reproduction, Fertility and Development. 2009;21(4):579-86 |
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Neural progenitors of the postnatal and adult mouse forebrain retain the ability to self-replicate, form neurospheres and undergo multipotent differentiation in vivo
Bettina Neumeister, Antje Grabosch, Onur Basak, Rolf Kemler and Verdon Taylor Stem Cells (Dayton, Ohio). 2009 Mar;27(3):714-23: 2008 Dec 18. [Epub ahead of print] |
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Progress toward
Pilar Pallares; Claudia Letelier; Antonio Gonzalez-Bulnes Fertility and Sterility. 2009 Feb;91(2):624-6. Epub 2008 Aug 9 |
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Ovarian Volume Measurements in Mice With High-Resolution Ultrasonography
Andrej Lyshchik, MD, PhD, Stephen B. Hobbs, Arthur C. Fleischer, MD, Dineo Khabele, MD, Deok-Soo Son, DVM, PhD, John C. Gore, PhD and Ronald R. Price, PhD J Ultrasound Med. 2007 Oct; 26(10), PP 1419-1425 |
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Biodegradable nanoparticles for targeted ultrasound imaging of breast cancer cells in vitro
Jun Liu, Jie Li, Thomas J Rosol, Xueliang Pan and Jeffrey L Voorhees PHYSICS IN MEDICINE AND BIOLOGY,2007 Aug 21;52(16):4739-47. Epub 2007 Jul 24 |
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3D Visualisation and Quantification by Microcomputed Tomography of Late Gestational Changes in the Arterial and Venous Feto-Placental Vasculature of the Mouse
M.Y. Rennie a, K.J. Whiteley b, S. Kulandavelu b,c, S.L. Adamson b,c, J.G. Sled Placenta. 2007 Aug-Sept; 28(8-9), PP 833-840; Epub 2007 Feb 23 |
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Developmental changes in hemodynamics of uterine artery, utero- and umbilicoplacental, and vitelline circulations in mouse throughout gestation
Junwu Mu1,2,3 and S. Lee Adamson1,2,3 American journal of physiology. Heart and circulatory physiology. 2006 Sep;291(3):H1421-8. Epub 2006 Apr 7 |
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Molecular and functional signature of heart hypertrophy during pregnancy
Eghbali M, Deva R, Alioua A, Minosyan TY, Ruan H, Wang Y, Toro L, Stefani E. Circ Res. 2005 Jun 10;96(11):1208-16. Epub 2005 May 19. |
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Ultrasonic detection and developmental changes in calcification of the placenta during normal pregnancy in mice
Akirav C, Lu Y, Mu J, Qu DW, Zhou YQ, Slevin J, Holmyard D, Foster FS, Adamson SL. Placenta. 2005 Feb-Mar;26(2-3):129-37. |
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Developmental changes in integrated ultrasound backscatter from embryonic blood in vivo in mice at high US frequency
Le Floc'h J, Cherin E, Zhang MY, Akirav C, Adamson SL, Vray D, Foster FS. Ultrasound Med Biol. 2004 Oct;30(10):1307-19. |
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Applications - Cancer Research
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Optical Imaging with Her2-Targeted Affibody Molecules Can Monitor Hsp90 Treatment Response in a Breast Cancer Xenograft Mouse Model
Stephanie M.W.Y. van de Ven1,2,4, Sjoerd G. Elias1,2,5, Carmel T. Chan1,2, Zheng Miao1,2, Zhen Cheng1,2, Abhijit De1,2,6, and Sanjiv S. Gambhir1,2,3 Clinical Cancer Research. 2012 Feb 15;18(4):1073-81. Epub 2012 Jan 10 |
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Modulation of the Tumor Microvasculature by Phosphoinositide-3 Kinase Inhibition Increases Doxorubicin Delivery In Vivo
Naseer Qayum1, Jaehong Im1, Michael R. Stratford1, Eric J. Bernhard2, W. Gillies McKenna1, and Ruth J. Muschel1 Clinical Cancer Research. 2012 Jan 1;18(1):161-9. Epub 2011 Nov 7 |
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Dual Inhibition of the PI3K/mTOR Pathway Increases Tumor Radiosensitivity by Normalizing Tumor Vasculature
Emmanouil Fokas1, Jae Hong Im1, Sally Hill1, Sabira Yameen1, Michael Stratford1, John Beech1, Wolfgang Hackl2, Sauveur-Michel Maira2, Eric J. Bernhard1, W. Gillies McKenna1, and Ruth J. Muschel1 Cancer Research. 2012 Jan 1;72(1):239-48. Epub 2011 Nov 22 |
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Volumetric and angiogenic evaluation of antitumor effects with acoustic liposome and high-frequency ultrasound
Tetsuya Kodama1, Noriko Tomita2, Yoko Yagishita3, Sachiko Horie4, Kenichi Funamoto2, Toshiyuki Hayase2, Maya Sakamoto5, and Shiro Mori5 Cancer Research. 2011 Nov 15;71(22):6957-64. Epub 2011 Oct 7 |
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Therapeutic Effect of Lenalidomide in a Novel Xenograft Mouse Model of Human Blastic NK Cell Lymphoma/Blastic Plasmacytoid Dendritic Cell Neoplasm
Alice Agliano1,2, Ines Martin-Padura1, Paola Marighetti1, Giuliana Gregato1, Angelica Calleri1, Celia Prior2, Miriam Redrado2, Alfonso Calvo2, and Francesco Bertolini1 Clinical Cancer Research. 2011 Oct 1;17(19):6163-73. Epub 2011 Aug 19 |
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Mutationally Activated BRAFV600E Elicits Papillary Thyroid Cancer in the Adult Mouse
Roch-Philippe Charles1,2, Gioia Iezza3, Elena Amendola4, David Dankort1,2, and Martin McMahon1,2 Cancer Research. 2011 Jun 1;71(11):3863-71. Epub 2011 Apr 21 |
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Proangiogenic Factor PlGF Programs CD11b+ Myelomonocytes in Breast Cancer during Differentiation of Their Hematopoietic Progenitors
Julien Laurent1, Eveline Faes-van\'t Hull1, Cedric Touvrey1, François Kuonen1, Qiang Lan1,5, Girieca Lorusso1,5, Marie-Agnès Doucey1, Laura Ciarloni1, Natsuko Imaizumi1, Gian Carlo Alghisi1, Ernesta Fagiani7, Khalil Zaman2, Roger Stupp4, Masabumi Shibuya8, Jean-François Delaloye3, Gerhard Christofori5,7, and Curzio Ruegg1,5,6 Cancer Research. 2011 Jun 1;71(11):3781-3791. Epub 2011 Apr 20 |
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Preclinical Models for Neuroblastoma: Establishing a Baseline for Treatment
Tal Teitz1, Jennifer J. Stanke1,2, Sara Federico2,3, Cori L. Bradley2, Rachel Brennan2, Jiakun Zhang2, Melissa D. Johnson4, Jan Sedlacik5, Madoka Inoue1, Ziwei M. Zhang4, Sharon Frase6, Jerold E. Rehg7, Claudia M. Hillenbrand5, David Finkelstein8, Christopher Calabrese4, Michael A. Dyer2,9,10, Jill M. Lahti1,11 PLoS One. 2011 Apr 29;6(4):e19133 |
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A perspective on vascular disrupting agents that interact with tubulin: preclinical tumor imaging and biological assessment
Ralph P. Mason, Dawen Zhao, Li Liu, Mary Lynn Trawick and Kevin G. Pinney Integrative Biology. 2011 Apr 1;3(4):375-87. Epub 2011 Feb 14 |
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Hepatocyte growth factor mobilizes non-bone marrow-derived circulating mesoangioblasts
Masayoshi Iwasaki1, Masamichi Koyanagi1, Hans Kossmann1, Nadejda Monsefi2, Stefan Rupp1,3, Janina Trauth1,3, Patrick Paulus4, Rebekka Goetz1,3, Stefan Momma5, Marc Tjwa1, Kisho Ohtani1, Reinhard Henschler6, Dietmar Schranz3, Giulio Cossu7, Kai Zacharowski4, Sven Martens2, Andreas M. Zeiher8 and Stefanie Dimmeler1 European Heart Journal. 2011 Mar;32(5):627-36. Epub 2010 Dec 29 |
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Tumor Angiogenic Marker Expression Levels during Tumor Growth: Longitudinal Assessment with Molecularly Targeted Microbubbles and US Imaging
Nirupama Deshpande, PhD, Ying Ren, MD1, Kira Foygel, PhD, Jarrett Rosenberg, PhD and Jürgen K. Willmann, MD Radiology. 2011 Mar;258(3):804-11. |
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Use of Macrophages to Target Therapeutic Adenovirus to Human Prostate Tumors
Munitta Muthana1, Athina Giannoudis5, Simon D. Scott6, Hsin-Yu Fang1, Seth B. Coffelt1, Fiona J. Morrow1, Craig Murdoch2, Julian Burton1, Neil Cross4, Bernard Burke7, Roshna Mistry8, Freddie Hamdy9, Nicola J. Brown3, Lindsay Georgopoulos8, Peter Hoskin10, Magnus Essand11, Claire E. Lewis1, and Norman J. Maitland8 Cancer Research. 2011 Mar 1;71(5):1805-15. Epub 2011 Jan 13. |
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HIF-1–Dependent Stromal Adaptation to Ischemia Mediates In Vivo Tumor Radiation Resistance
David L. Schwartz1,2, James Bankson3, Luc Bidaut3, Yi He1, Ryan Williams4, Robert Lemos4, Arun Kumar Thitai2, Junghwan Oh1, Andrei Volgin2, Suren Soghomonyan2, Hsin-Hsien Yeh2, Ryuichi Nishii2, Uday Mukhopadhay2, Mian Alauddin2, Ioseb Mushkudiani2, Norihito Kuno1, Sunil Krishnan1, William Bornman4, Stephen Y. Lai5, Garth Powis4, John Hazle3 and Juri Gelovani2 Molecular Cancer Research. 2011 Mar;9(3):259-70. Epub 2011 Mar 1. |
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Assessment and monitoring tumor vascularity with contrast-enhanced ultrasound maximum intensity persistence imaging
Pysz, Marybeth A. PhD; Foygel, Kira PhD; Panje, Cedric M. BS; Needles, Andrew BASc; Tian, Lu PhD; Willmann, Jürgen K. MD Investigative Radiology. 2011 Mar;46(3):187-95. |
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Fes Tyrosine Kinase Expression in the Tumor Niche Correlates with Enhanced Tumor Growth, Angiogenesis, Circulating Tumor Cells, Metastasis, and Infiltrating Macrophages
Shengnan Zhang1, Violeta Chitu2, E. Richard Stanley2, Bruce E. Elliott1, and Peter A. Greer1 Cancer Research. 2011 Feb 15;71(4):1465-73. Epub 2010 Dec 15. |
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Mitochondrial Targeting of Vitamin E Succinate Enhances Its Pro-apoptotic and Anti-cancer Activity via Mitochondrial Complex II
Lan-Feng Dong1, Victoria J. A. Jameson2, David Tilly3, Jiri Cerny4, Elahe Mahdavian5, Alvaro MarÃn-Hernández6, Luz Hernández-Esquivel6, Sara RodrÃguez-EnrÃquez6, Jan Stursa7, Paul K. Witting8, Bela Stantic9, Jakub Rohlena4, Jaroslav Truksa4, Katarina Kluckova4, Jeffrey C. Dyason10, Miroslav Ledvina7, Brian A. Salvatore5, Rafael Moreno-Sánchez6, Mark J. Coster3, Stephen J. Ralph1, Robin A. J. Smith2 and Jiri Neuzil1,10 The Journal of Biological Chemistry. 2011 Feb 4;286(5):3717-28. Epub 2010 Nov 8 |
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In Vivo High-Frequency, Contrast-Enhanced Ultrasonography of Uveal Melanoma in Mice: Imaging Features and Histopathologic Correlations
Qing Zhang1,2,3, Hua Yang1,3, Shin J. Kang1, Yanggan Wang4, Geoffrey D. Wang5, Tonya Coulthard6 and Hans E. Grossniklaus1,7 Investigative Ophthalmology and Visual Science. 2011 Jan 18. [Epub ahead of print] |
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Improved Detection of Regional Melanoma Metastasis Using 18F-6-Fluoro-N-[2-(Diethylamino)Ethyl] Pyridine-3-Carboxamide, a Melanin-Specific PET Probe, by Perilesional Administration
Delphine Denoyer1, Titaina Potdevin1, Peter Roselt1, Oliver C. Neels1, Laura Kirby1, Ivan Greguric2, Andrew Katsifis2, Donna S. Dorow1 and Rodney J. Hicks1,3 The Journal of Nuclear Medicine. 2011 Jan;52(1):115-22. Epub 2010 Dec 13. |
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SSTR2-based reporters for assessing gene transfer into non-small cell lung cancer: evaluation using an intrathoracic mouse model
S.P. Singh,1 L. Han,1 R. Murali,1 L. Solis,2 J. Roth,3 L. Ji,4 I. Wistuba,2 and V. Kundra1,5 Human Gene Therapy. 2011 Jan;22(1):55-64. Epub 2010 Dec 6 |
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Nox2 NADPH Oxidase Promotes Pathologic Cardiac Remodeling Associated with Doxorubicin Chemotherapy
Youyou Zhao1, Declan McLaughlin1, Emma Robinson1, Adam P. Harvey1, Michelle B. Hookham1, Ajay M. Shah2, Barbara J. McDermott1, and David J. Grieve1 Cancer Research. 2010 Nov 15;70(22):9287-97. Epub 2010 Sep 30. |
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Enzymatic Depletion of Tumor Hyaluronan Induces Antitumor Responses in Preclinical Animal Models
Curtis B. Thompson, H. Michael Shepard, Patrick M. O\'Connor, Salam Kadhim, Ping Jiang, Ryan J. Osgood, Louis H. Bookbinder, Xiaoming Li, Barry J. Sugarman, Robert J. Connor, Sinisa Nadjsombati and Gregory I. Frost Molecular Cancer Therapeutics. 2010 Nov;9(11):3052-64. Epub 2010 Oct 26 |
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Anti–αv Integrin Monoclonal Antibody Intetumumab Enhances the Efficacy of Radiation Therapy and Reduces Metastasis of Human Cancer Xenografts in Nude Rats
Shoucheng Ning1, Junqiang Tian1, Deborah J. Marshall2, and Susan J. Knox1 Cancer Research. 2010 Oct 1;70(19):7591-9. Epub 2010 Sep 14 |
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Notch3 in Human Breast Cancer Cell Lines Regulates Osteoblast-Cancer Cell Interactions and Osteolytic Bone Metastasis
Zhiyuan Zhang1,5, Hao Wang1, Sadakatsu Ikeda2, Frederic Fahey3, Diane Bielenberg4, Patrick Smits1 and Peter V. Hauschka1,5 The American Journal of Pathology. 2010 Sep;177(3):1459-69. Epub 2010 Jul 22 |
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Cytosolic Phospholipase A2 and Lysophospholipids in Tumor Angiogenesis
Amanda G. Linkous, Eugenia M. Yazlovitskaya, Dennis E. Hallahan Journal of the National Cancer Institute. 2010 Aug 20. [Epub ahead of print] |
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Murine echocardiography and ultrasound imaging
A Pistner, S Belmonte, T Coulthard, and B Blaxall Journal of Visualized Experiments : JoVE 2010 Aug 8;(42). pii: 2100 |
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Systemic Administration of Polymeric Nanoparticle-Encapsulated Curcumin (NanoCurc) Blocks Tumor Growth and Metastases in Preclinical Models of Pancreatic Cancer
Savita Bisht1, Masamichi Mizuma1, Georg Feldmann1,5, Niki A. Ottenhof1,6, Seung-Mo Hong1,2, Dipankar Pramanik1, Venugopal Chenna1, Collins Karikari1, Rajni Sharma1,2, Michael G. Goggins1,2,3,4, Michelle A. Rudek3, Rajani Ravi3, Amarnath Maitra7 and Anirban Maitra1,2,3 Molecular Cancer Therapeutics. 2010 Jul 20. [Epub ahead of print] |
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p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal
Zhen Zhao1,2, Johannes Zuber1, Ernesto Diaz-Flores3, Laura Lintault1,4, Scott C. Kogan5, Kevin Shannon3 and Scott W. Lowe1,4 Genes & Development. 2010 Jul 1;24(13):1389-402 |
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Radiosensitization and stromal imaging response correlates for the HIF-1 inhibitor PX-478 given with or without chemotherapy in pancreatic cancer
David L. Schwartz1,2, James A. Bankson3, Robert Lemos, Jr.4, Stephen Y. Lai5, Arun K. Thittai1, Yi He1, Galen Hostetter6, Michael J. Demeure6, Daniel D. Von Hoff6, and Garth Powis5 Molecular Cancer Therapeutics. 2010 Jul;9(7):2057-67. Epub 2010 Jun 29 |
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Inhibition of lung tumor growth by complex pulmonary delivery of drugs with oligonucleotides as suppressors of cellular resistance
Olga B. Garbuzenko1, Maha Saad1, Vitaly P. Pozharov1, Kenneth R. Reuhl2,3,4, Gediminas Mainelis3,5, and Tamara Minko1,3,4 Proceedings of the National Academy of Sciences of the United States of America. 2010 Jun 8;107(23):10737-42. Epub 2010 May 24 |
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Volume of Preclinical Xenograft Tumors Is More Accurately Assessed by Ultrasound Imaging Than Manual Caliper Measurements
Gregory D. Ayers, MS, Eliot T. McKinley, BSE, Ping Zhao, BS, Jordan M. Fritz, BS, Rebecca E. Metry, BS, Brenton C. Deal, BS, Katrina M. Adlerz, BS, Robert J. Coffey, MD and H. Charles Manning, PhD Journal of Ultrasound in Medicine. 2010 Jun;29(6):891-901 |
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Antiangiogenic Cancer Therapy: Monitoring with Molecular US and a Clinically Translatable Contrast Agent (BR55)
Marybeth A. Pysz, PhD, Kira Foygel, PhD, Jarrett Rosenberg, PhD, Sanjiv S. Gambhir, MD, PhD, Michel Schneider, PhD and Jürgen K. Willmann, MD Radiology. 2010 Jun 1. [Epub ahead of print] |
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Assessing therapeutic responses in Kras mutant cancers using genetically engineered mouse models
Mallika Singh, Anthony Lima, Rafael Molina, Patricia Hamilton, Anne C Clermont, Vidusha Devasthali, Jennifer D Thompson, Jason H Cheng, Hani Bou Reslan, Calvin C K Ho, Timothy C Cao, Chingwei V Lee, Michelle A Nannini, Germaine Fuh, Richard A D Carano, Hartmut Koeppen, Ron X Yu, William F Forrest, Gregory D Plowman & Leisa Johnson Nature Biotechnology. 2010 Jun;28(6):585-93. Epub 2010 May 23 |
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Serial Transcriptome Analysis and Cross-Species Integration Identifies Centromere-Associated Protein E as a Novel Neuroblastoma Target
Naomi J. Balamuth1, Andrew Wood1, Qun Wang1, Jayanti Jagannathan1, Patrick Mayes1, Zhe Zhang2, Zhongxue Chen2, Eric Rappaport3, Joshua Courtright1, Bruce Pawel4, Barbara Weber6, Richard Wooster6, Eric O. Sekyere7, Glenn M. Marshall7 and John M. Maris1,5 Cancer Research. 2010 Apr 1;70(7):2749-58. Epub 2010 Mar 16 |
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Correlation Between 2- and 3-Dimensional Assessment of Tumor Volume and Vascular Density by Ultrasonography in a Transgenic Mouse Model of Mammary Carcinoma
Lei Zhao, PhD, Yutian Zhan, MS, J. Lynn Rutkowski, PhD, Giora Z. Feuerstein, MD and Xinkang Wang, PhD Journal of Ultrasound in Medicine. 2010 Apr;29(4):587-95 |
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Correlation of Quantified Contrast-Enhanced Sonography With In Vivo Tumor Response
Misun Hwang, BS, Ghazal Hariri, MS, Andrej Lyshchik, MD, PhD, Dennis E. Hallahan, MD and Arthur C. Fleischer, MD Journal of Ultrasound in Medicine. 2010 Apr;29(4):597-607 |
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Lipid membrane editing with peptide cargo linkers in cells and synthetic nanostructures
Hua Pan, Jacob W. Myerson, Olena Ivashyna, Neelesh R. Soman, Jon N. Marsh, Joshua L. Hood, Gregory M. Lanza, Paul H. Schlesinger, and Samuel A. Wickline The FASEB Journal. 2010 Mar 24. [Epub ahead of print] |
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Targeted Contrast-Enhanced Ultrasound Imaging of Tumor Angiogenesis with Contrast Microbubbles Conjugated to Integrin-Binding Knottin Peptides
Jürgen K. Willmann 1, Richard H. Kimura 2, Nirupama Deshpande 1, Amelie M. Lutz 1, Jennifer R. Cochran 3, and Sanjiv S. Gambhir 2 The Journal of Nuclear Medicine. 2010 Mar;51(3):433-40. Epub 2010 Feb 11 |
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IFN-ß Restricts Tumor Growth and Sensitizes Alveolar Rhabdomyosarcoma to Ionizing Radiation
Thomas L. Sims1,4, Mackenzie McGee1, Regan F. Williams1,4, Adrianne L. Myers1,4, Lorraine Tracey1, J. Blair Hamner1,4, Catherine Ng1, Jianrong Wu2, M. Waleed Gaber5, Beth McCarville3, Amit C. Nathwani6 and Andrew M. Davidoff1,4 Molecular Cancer Therapeutics. 2010 Mar;9(3):761-71. Epub 2010 Mar 2 |
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Paracrine Regulation of Pancreatic Cancer Cell Invasion by Peripheral Nerves
Ziv Gil, Oren Cavel, Kaitlyn Kelly, Peter Brader, Avigail Rein, Sizhi P. Gao, Diane L. Carlson, Jatin P. Shah, Yuman Fong, Richard J. Wong Journal of the National Cancer Institute. 2010 Jan 12. [Epub ahead of print] |
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Quantifying Antivascular Effects of Monoclonal Antibodies to Vascular Endothelial Growth Factor: Insights from Imaging
James P.B. O'Connor1,2, Richard A.D. Carano3, Andrew R. Clamp2, Jed Ross3, Calvin C.K. Ho3, Alan Jackson1, Geoff J.M. Parker1, Chris J. Rose1, Franklin V. Peale4, Michel Friesenhahn5, Claire L. Mitchell1,2, Yvonne Watson1, Caleb Roberts1, Lynn Hope2, Sue Cheung1, Hani Bou Reslan3, Mary Ann T. Go6, Glenn J. Pacheco6, Xiumin Wu7, Tim C. Cao3, Sarajane Ross6, Giovanni A. Buonaccorsi1, Karen Davies1, Jurjees Hasan2, Paula Thornton2, Olivia del Puerto8, Napoleone Ferrara7, Nicholas van Bruggen3 and Gordon C. Jayson2 Clinical Cancer Research. 2009 Nov 2; 15(21):6674–82 |
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In vivo, Noninvasive, Label-Free Detection and Eradication of Circulating Metastatic Melanoma Cells Using Two-Color Photoacoustic Flow Cytometry with a Diode Laser
Ekaterina I. Galanzha 1, 2, Evgeny V. Shashkov 1, Paul M. Spring 2, James Y. Suen 2, and Vladimir P. Zharov 1, 2 Cancer Research. 2009 Oct 15;69(20):7926-34. Epub 2009 Oct 13 |
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Morphological ultrasound micro-imaging of thyroid in living mice
Marcello Mancini, Emilia Vergara, Giuliana Salvatore, Adelaide Greco, Giancarlo Troncone, Andrea Affuso, Raffaele Liuzzi, Paolo Salerno, Maria Scotto di Santolo, Massimo Santoro, Arturo Brunetti, and Marco Salvatore Endocrinology. 2009 Oct;150(10):4810-5. Epub 2009 Jul 9 |
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Inhibition of Hsp90 via 17-DMAG induces apoptosis in a p53-dependent manner to prevent medulloblastoma
Olivier Ayrault1, Michael D. Godeny2, Christopher Dillon2, Frederique Zindy1, Patrick Fitzgerald2, Martine F. Roussel1 and Helen M. Beere2 Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2009 Oct 6;106(40):17037-42. Epub 2009 Sep 23 |
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Inhibition of Tumor Growth Progression by Antiandrogens and mTOR Inhibitor in a Pten-Deficient Mouse Model of Prostate Cancer
Weisheng Zhang 1, Joe Zhu 1, Clay L. Efferson 2, Chris Ware 3, Jennifer Tammam 2, Minilik Angagaw 4, Jason Laskey 2, Kimberly A. Bettano 1, Shailaja Kasibhatla 2, John F. Reilly 3, Cyrille Sur 5, and Pradip K. Majumder 2 Cancer Research. 2009 Sep 15;69(18):7466-72. Epub 2009 Sep 8 |
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Tumor Vascular Changes Mediated by Inhibition of Oncogenic Signaling
Naseer Qayum 1, Ruth J. Muschel 1, Jae Hong Im 1, Lukxmi Balathasan 1, Cameron J. Koch 2, Sonal Patel 3, W. Gillies McKenna 1, and Eric J. Bernhard 1 Cancer Research. 2009 Aug 1;69(15):6347-54. Epub 2009 Jul 21 |
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Prostate-specific Klf6 Inactivation Impairs Anterior Prostate Branching Morphogenesis through Increased Activation of the Shh Pathway
Ching Ching Leow1, Bu-er Wang1, Jed Ross2, Sara M. Chan3, Jiping Zha3, Richard A. D. Carano2, Gretchen Frantz3, Michael M. Shen4, Frederic J. de Sauvage1, and Wei-Qiang Gao1 The Journal of biological chemistry. 2009 Jul 31;284(31):21057-65. Epub 2009 Jun 3 |
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Coregistration of ultrasonography and magnetic resonance imaging with a preliminary investigation of the spatial colocalization of vascular endothelial growth factor receptor 2 expression and tumor perfusion in a murine tumor model
Mary E. Loveless, Jennifer G. Whisenant, Kevin Wilson, Andrej Lyshchik, Tuhin K. Sinha, John C. Gore, Thomas E. Yankeelov Molecular Imaging. 2009 Jul-Aug;8(4):187-98 |
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Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer
Kenneth P. Olive 1, Michael A. Jacobetz 1, Christian J. Davidson 2, Aarthi Gopinathan 3, Dominick McIntyre 1, Davina Honess 1, Basetti Madhu 1, Mae A. Goldgraben 1, Meredith E. Caldwell 1, David Allard 1, Kristopher K. Frese 1, Gina DeNicola 3, Christine Feig 1, Chelsea Combs 2, Stephen P. Winter 1, Heather Ireland 1, Stefanie Reichelt 1, William J. Howat 1, Alex Chang 4, Mousumi Dhara 4, Lifu Wang 5, Felix Rückert 6, Robert Grützmann 6, Christian Pilarsky 6, Kamel Izeradjene 7, Sunil R. Hingorani 7, Pearl Huang 8, Susan E. Davies 9, William Plunkett 10, Merrill Egorin 11, Ralph H. Hruban 4, Nigel Whitebread 12, Karen McGovern 12, Julian Adams 12, Christine Iacobuzio-Donahue 4, John Griffiths 1, David A. Tuveson 1 Sciencexpress. 2009 Jun 12;324(5933):1457-61. Epub 2009 May 21 |
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Sunitinib and PF-562,271 (FAK/Pyk2 inhibitor) effectively block growth and recovery of human hepatocellular carcinoma in a rat xenograft model
Cedo M. Bagi,1 James Christensen,2 Darrel P. Cohen,2 Walter G. Roberts,3 Dean Wilkie,4 Terri Swanson,1 Theresa Tuthill5 and Catharine J. Andresen1 Cancer Biology & Therapy. 2009 May;8(9):856-65 |
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Complementarity of ultrasound and fluorescence imaging in an orthotopic mouse model of pancreatic cancer
Cynthia S Snyder1 , Sharmeela Kaushal1 , Yuko Kono2 , Hop S Tran Cao3 , Robert M Hoffman3,4 and Michael Bouvet1,3 BMC Cancer. 2009 Apr 8;9(1):106. [Epub ahead of print] |
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The selective hypoxia inducible factor-1 inhibitor PX-478 provides in vivo radiosensitization through tumor stromal effects
David L. Schwartz1,2, Garth Powis3, Arun Thitai-Kumar2, Yi He1, James Bankson4, Ryan Williams3, Robert Lemos3, Junghwan Oh1, Andrei Volgin2, Suren Soghomonyan2, Ryuichi Nishii2, Mian Alauddin2, Uday Mukhopadhay2, Zhenghong Peng3, William Bornmann3 and Juri Gelovani2 Molecular Cancer Therapeutics. 2009 Apr 1; 8(4):947–58 |
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Effective prostate cancer chemopreventive intervention with green tea polyphenols in the TRAMP model depends on the stage of the disease
Vaqar Mustafa Adhami, Imtiaz Ahmad Siddiqui, Sami Sarfaraz, Sabih Islam Khwaja, Bilal Bin Hafeez, Nihal Ahmad and Hasan Mukhtar Clinical Cancer Research. 2009 Mar 15;15(6):1947-53. Epub 2009 Mar 10 |
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Quantitative Ultrasound Characterization of Responses to Radiotherapy in Cancer Mouse Models
Roxana M. Vlad 1, 3, Sebastian Brand 5, Anoja Giles 3, Michael C. Kolios 1, 4, Gregory J. Czarnota 1, 2, 3 Clinical Cancer Research. 2009 Mar 15;15(6):2067-75. Epub 2009 Mar 10 |
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Cytosolic Phospholipase A2: Targeting Cancer through the Tumor Vasculature
Amanda Linkous, Ling Geng, Andrej Lyshchik, Dennis E. Hallahan, Eugenia M. Yazlovitskaya Clinical Cancer Research. 2009 Mar 1;15(5):1635-44. Epub 2009 Feb 24 |
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Suppression of Tumor Growth In vivo by the Mitocan {alpha}-tocopheryl Succinate Requires Respiratory Complex II
Lan-Feng Dong, Ruth Freeman, Ji Liu, Renata Zobalova, AlvaroMarin-Hernandez, Marina Stantic, Jakub Rohlena, Karel Valis, Sara Rodriguez-Enriquez, Bevan Butcher, Jacob Goodwin, Ulf T. Brunk, Paul K. Witting, RafaelMoreno-Sanchez, Immo E. Scheffler, Stephen J. Ralph, and Jiri Neuzil Clinical Cancer Research 2009 Mar 1;15(5):1593-600. Epub 2009 Feb 17 |
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A Method for Assessing the Microvasculature in a Murine Tumor Model Using Contrast-Enhanced Ultrasonography
Mary E. Loveless, MS, Xia Li, PhD, Jessica Huamani, MS, Andrej Lyshchik, MD, PhD, Benoit Dawant, PhD, Dennis Hallahan, MD, John C. Gore, PhD, Thomas E. Yankeelov, PhD Journal of ultrasound in medicine. 2008 Dec; 27(12):1699-709 |
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Interstitial Doppler Optical Coherence Tomography as a Local Tumor Necrosis Predictor in Photodynamic Therapy of Prostatic Carcinoma: An In vivo Study
Beau A. Standish, Kenneth K.C. Lee, Xiao Jin, Adrian Mariampillai, Nigel R. Munce, Michael F.G. Wood, Brian C. Wilson, I. Alex Vitkin, and Victor X.D. Yang Cancer Research. 2008 Dec 1;68(23):9987-95 |
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ODC1 Is a Critical Determinant of MYCN Oncogenesis and a Therapeutic Target in Neuroblastoma
Michael D. Hogarty1,2, Murray D. Norris5, Kimberly Davis1, Xueyuan Liu1, Nicholas F. Evageliou1, Candace S. Hayes7, Bruce Pawel3, Rong Guo4, Huaqing Zhao4, Eric Sekyere5, Joanna Keating5, Wayne Thomas5, Ngan Ching Cheng5, Jayne Murray5, Janice Smith5, Rosemary Sutton5, Nicola Venn5, Wendy B. London8, Allen Buxton8, Susan K. Gilmour7, Glenn M. Marshall5,6 and Michelle Haber5 Cancer Research. 2008 Dec 1;68(23):9735-45 |
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Molecular Imaging of Therapeutic Response to Epidermal Growth Factor Receptor Blockade in Colorectal Cancer
H. Charles Manning, Nipun B. Merchant, A. Coe Foutch, John M. Virostko, Shelby K. Wyatt, Chirayu Shah, Eliot T. McKinley, Jingping Xie, Nathan J. Mutic, M. Kay Washington, Bonnie LaFleur, Mohammed Noor Tantawy, Todd E. Peterson, M. Sib Ansari, Ronald M. Baldwin, Mace L. Rothenberg, Darryl J. Bornhop, John C. Gore, and Robert J. Coffey Clin. Cancer Res. 2008 Nov 15;14(22):7413-22 |
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Early therapy evaluation of combined anti-death receptor 5 antibody and gemcitabine in orthotopic pancreatic tumor xenografts by diffusion-weighted magnetic resonance imaging
Kim H, Morgan DE, Buchsbaum DJ, Zeng H, Grizzle WE, Warram JM, Stockard CR, McNally LR, Long JW, Sellers JC, Forero A, Zinn KR. Cancer Research. 2008 Oct 15;68(20):8369-76. |
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Ultrasound imaging of apoptosis in tumor response: novel preclinical monitoring of photodynamic therapy effects
Banihashemi B, Vlad R, Debeljevic B, Giles A, Kolios MC, Czarnota GJ. Cancer Research. 2008 Oct 15;68(20):8590-6. |
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Biomedical imaging in the safety evaluation of new drugs
Yi-Xiang J Wang and Sen-Xiang Yan Laboratory Animals. 2008 Oct;42(4):433-41. |
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Targeted Microbubbles for Imaging Tumor Angiogenesis: Assessment of Whole-Body Biodistribution with Dynamic Micro-PET in Mice
Jürgen K. Willmann, MD; Zhen Cheng, PhD; Corrine Davis, DVM, PhD; Amelie M. Lutz, MD; Meike L. Schipper, MD; Carsten H. Nielsen, BS; Sanjiv S. Gambhir, MD, PhD Radiology. 2008 Oct; 249(1): 212-9 |
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An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer
Georg Feldmann,, Volker Fendrich, Karen McGovern, Djahida Bedja, Savita Bisht, Hector Alvarez,, Jan-Bart M. Koorstra, Nils Habbe,, Collins Karikari, Michael Mullendore,, Kathleen L. Gabrielson, Rajni Sharma, William Matsui, and Anirban Maitra Molecular Cancer Therapeutics. 2008 Sep; 7(9):2725-35 |
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Dual-targeted Contrast Agent for US Assessment of Tumor Angiogenesis in Vivo
Jürgen K. Willmann, MD; Amelie M. Lutz, MD; Ramasamy Paulmurugan, PhD; Manishkumar R. Patel, PhD; Pauline Chu, BA; Jarrett Rosenberg, PhD; Sanjiv S. Gambhir, MD, PhD Radiology. 2008 Sep;248(3):936-44 |
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Vessel Fractions in Tumor Xenografts Depicted by Flow- or Contrast-Sensitive Three-Dimensional High-Frequency Doppler Ultrasound Respond Differently to Antiangiogenic Treatment
Moritz Palmowski, Jochen Huppert, Peter Hauff, Michael Reinhardt, Karin Schreiner, Michaela A. Socher, Peter Hallscheidt, Guenter W. Kauffmann, Wolfhard Semmler, and Fabian Kiessling Cancer Research. 2008 Sep 1;68(17):7042-9 |
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Imaging Hypoxia in Orthotopic Rat Liver Tumors with Iodine 124-labeled Iodoazomycin Galactopyranoside PET
Christopher C. Riedl,MD; Peter Brader,MD; Pat B. Zanzonico, PhD; Yun Shin Chun,MD; Yanghee Woo, MD; Paramjeet Singh, MD; Sean Carlin, PhD; Bixiu Wen,MD; C. Clifton Ling, PhD; Hedvig Hricak,MD; Yuman Fong, MD Radiology. 2008 Aug;248(2):561-70 |
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Attenuated multimutated herpes simplex virus-1 effectively treats prostate carcinomas with neural invasion while preserving nerve function
Kelly K, Brader P, Rein A, Shah JP, Wong RJ, Fong Y, Gil Z The Journal of the Federation of American Societies for Experimental Biology. 2008 Jun;22(6):1839-48. |
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MetMAb, the one-armed 5D5 anti-c-Met antibody, inhibits orthotopic pancreatic tumor growth and improves survival
Jin H, Yang R, Zheng Z, Romero M, Ross J, Bou-Reslan H, Carano RA, Kasman I, Mai E, Young J, Zha J, Zhang Z, Ross S, Schwall R, Colbern G, Merchant M Cancer Research. 2008 Jun 1;68(11):4360-8. |
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Volumetric high-frequency Doppler ultrasound enables the assessment of early antiangiogenic therapy effects on tumor xenografts in nude mice
Jugold M, Palmowski M, Huppert J, Woenne EC, Mueller MM, Semmler W, Kiessling F. Eur Radiol. 2008 Apr;18(4):753-8. Epub 2007 Dec 15 |
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Urocortin2 inhibits tumor growth via effects on vascularization and cell proliferation
Zhengrong Hao, Yan Huang, Jake Cleman, Ion S. Jovin, Wylie W. Vale, Tracy L. Bale, and Frank J. Giordano Proceedings of the National Academy of Sciences. 2008 March 11;105(10): 3939-3944 |
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Mitogen-activated protein kinase kinase signaling promotes growth and vascularization of fibrosarcoma
Yan Ding, Elissa A. Boguslawski, Bree D. Berghuis, John J. Young, Zhongfa Zhang, Kim Hardy, Kyle Furge, Eric Kort, Arthur E. Frankel, Rick V. Hay, James H. Resau and Nicholas S. Duesbery Molecular Cancer Therapeutics. 2008 March 1;7: 648-658. |
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{alpha}2{beta}1 integrin expression in the tumor microenvironment enhances tumor angiogenesis in a tumor cell-specific manner
Zhang Z, Ramirez NE, Yankeelov TE, Li Z, Ford LE, Qi Y, Pozzi A, Zutter MM Blood. 2008 Feb 15;111(4):1980-8. |
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US Imaging of Tumor Angiogenesis with Microbubbles Targeted to Vascular Endothelial Growth Factor Receptor Type 2 in Mice
Jürgen K. Willmann, MD; Ramasamy Paulmurugan, PhD; Kai Chen, PhD; Olivier Gheysens, MD; Martin Rodriguez-Porcel, MD; Amelie M. Lutz, MD; Ian Y. Chen, MSE; Xiaoyuan Chen, PhD; Sanjiv S. Gambhir, MD, PhD Radiology. 2008 Feb; 246(2):508-18. Epub 2008 Jan 7 |
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Measurement of Human Choroidal Melanoma Xenograft Volume in Rats Using High-Frequency Ultrasound
Rod D. Braun and Kerry S. Vistisen Investigative Ophthalmology and Visual Science. 2008 Jan;49(1):16-22 |
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Vitamin E analogues inhibit angiogenesis by selective induction of apoptosis in proliferating endothelial cells: the role of oxidative stress
Lan-Feng Dong, Emma Swettenham, Johanna Eliasson, Xiu-Fang Wang, Mikhal Gold, Yasmine Medunic, Marina Stantic, Pauline Low, LubomirPr ochazka, Paul K. Witting, Jaroslav Turanek, Emmanuel T. Akporiaye, Stephen J. Ralph, and Jiri Neuzil Cancer Research. 2007 Dec 15;67(24):11906-13. |
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TRA-8 anti-DR5 monoclonal antibody and gemcitabine induce apoptosis and inhibit radiologically validated orthotopic pancreatic tumor growth
Derosier LC, Vickers SM, Zinn KR, Huang Z, Wang W, Grizzle WE, Sellers J, Stockard CR Jr, Zhou T, Oliver PG, Arnoletti P, Lobuglio AF, Buchsbaum DJ. Mol Cancer Ther. 2007 Dec;6(12):3198-207. |
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Rapid reversal of interleukin-6-dependent epithelial invasion in a mouse model of microbially induced colon carcinoma
Theofilos Poutahidis1,5, Kevin M. Haigis2,6, Varada P. Rao1, Prashant R. Nambiar1, Christie L. Taylor1, Zhongming Ge1, Koichiro Watanabe1, Anne Davidson3,7, Bruce H. Horwitz4, James G. Fox1 and Susan E. Erdman1 Carcinogenesis. 2007 Dec;28(12):2614-23. Epub 2007 Aug 27 |
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Molecular Imaging Of Vascular Endothelial Growth Factor Receptor 2 Expression Using Targeted Contrast-Enhanced High-Frequency Ultrasonography
Lyshchik A, Fleischer AC, Huamani J, Hallahan DE, Brissova M, Gore JC J Ultrasound Med. 2007 Nov;26(11):1575-86. |
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Imaging of hypoxia-driven gene expression in an orthotopic liver tumor model
Peter Brader1, Christopher Cesare Riedl1, Yanghee Woo2, Vladimir Ponomarev1, Pat Zanzonico3, Bixiu Wen3, Shangde Cai4, Hedvig Hricak1, Yuman Fong2, Ronald Blasberg1,5 and Inna Serganova5 Molecular Cancer Therapeutics. 2007 Nov;6(11):2900-8. Epub 2007 Nov 7 |
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Ovarian Volume Measurements in Mice With High-Resolution Ultrasonography
Andrej Lyshchik, MD, PhD, Stephen B. Hobbs, Arthur C. Fleischer, MD, Dineo Khabele, MD, Deok-Soo Son, DVM, PhD, John C. Gore, PhD and Ronald R. Price, PhD J Ultrasound Med. 2007 Oct; 26(10), PP 1419-1425 |
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Microultrasound Molecular Imaging of Vascular Endothelial Growth Factor Receptor 2 in a Mouse Model of Tumor Angiogenesis
Joshua J. Rychak, James Graba, Alison M.Y. Cheung, Bina S. Mystry, Jonathan R. Lindner, Robert S. Kerbel, and F. Stuart Foster Molecular Imaging. 2007 Sep-Oct; 6(5): PP. 289–296 |
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Combination Treatment with TRA-8 Anti Death Receptor 5 Antibody and CPT-11 Induces Tumor Regression in an Orthotopic Model of Pancreatic Cancer
Derosier LC, Buchsbaum DJ, Oliver PG, Huang ZQ, Sellers JC, Grizzle WE, Wang W, Zhou T, Zinn KR, Long JW, Vickers SM Clin Cancer Res. 2007 Sep 15;13(18):5535s-43s |
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Biodegradable nanoparticles for targeted ultrasound imaging of breast cancer cells in vitro
Jun Liu, Jie Li, Thomas J Rosol, Xueliang Pan and Jeffrey L Voorhees PHYSICS IN MEDICINE AND BIOLOGY,2007 Aug 21;52(16):4739-47. Epub 2007 Jul 24 |
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Detecting Vascular Changes In Tumour Xenografts Using Micro-Ultrasound And Micro-Ct Following Treatment With VEGFR-2 Blocking Antibodies
ALISON M. Y. CHEUNG,* ALLISON S. BROWN,* VIVIENE CUCEVIC,* MARCIA ROY,* ANDREW NEEDLES,* VICTOR YANG,* DANIEL J. HICKLIN,‡ ROBERT S. KERBEL,† and F. STUART FOSTER* Ultrasound in Med. & Biol. 2007 Aug;33(8):1259-68. Epub 2007 Apr 30 |
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Ultrasound biomicroscopy permits in vivo characterization of zebrafish liver tumors
Goessling W, North TE, Zon LI. Nat Methods. 2007 Jul;4(7):551-3. Epub 2007 Jun 17 |
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Therapeutic effect of CS-706, a specific cyclooxygenase-2 inhibitor, on gallbladder carcinoma in BK5.ErbB-2 mice
Kiguchi K, Ruffino L, Kawamoto T, Franco E, Kurakata S, Fujiwara K, Hanai M, Rumi M, Digiovanni J. Mol Cancer Ther. 2007 Jun;6(6):1709-17. |
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Vitamin E Analogs, a Novel Group of
Jiri Neuzil, Marco Tomasetti, Yan Zhao, Lan-Feng Dong, Marc Birringer, Xiu-Fang Wang, Pauline Low, Kun Wu, Brian A. Salvatore, and Steven J. Ralph Molecular Pharmacology. 2007 May;71(5):1185-99. Epub 2007 Jan 12 |
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Design, calibration and evaluation of a robotic needle-positioning system for small animal imaging applications
Waspe AC, Cakiroglu HJ, Lacefield JC, Fenster A. Phys Med Biol. 2007 Apr 7;52(7):1863-78. Epub 2007 Mar 9. |
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A Peptide Conjugate of Vitamin E Succinate Targets Breast Cancer Cells with High ErbB2 Expression
Wang XF, Birringer M, Dong LF, Veprek P, Low P, Swettenham E, Stantic M, Yuan LH, Zobalova R, Wu K, Ledvina M, Ralph SJ, Neuzil J. Cancer Res. 2007 Apr 1;67(7):3337-44. |
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Functional Neoangiogenesis Imaging of Genetically Engineered Mouse Prostate Cancer Using Three-Dimensional Power Doppler Ultrasound
Jim W. Xuan,1, Michael Bygrave6, Hongyi Jiang1, Fatma Valiyeva1, Joy Dunmore-Buyze6, David W. Holdsworth2,6, Jonathan I. Izawa1, Glenn Bauman3, Madeleine Moussa4, Scott F. Winter7, Norman M. Greenberg7, Joseph L. Chin1, Maria Drangova2,6, Aaron Fenster2,3,6 and James C. Lacefield2,5,6 Cancer Research. 2007 Mar 15; 67, 2830-2839 |
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Ultrasonic characterization of whole cells and isolated nuclei
Taggart LR, Baddour RE, Giles A, Czarnota GJ, Kolios MC. Ultrasound Med Biol. 2007 Mar;33(3):389-401 |
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Blockade of Hedgehog Signaling Inhibits Pancreatic Cancer Invasion and Metastases: A New Paradigm for Combination Therapy in Solid Cancers
Georg Feldmann1,5, Surajit Dhara1,5, Volker Fendrich2, Djahida Bedja3, Robert Beaty1,5, Michael Mullendore1,5, Collins Karikari1,5, Hector Alvarez1,5, Christine Iacobuzio-Donahue1,5, Antonio Jimeno4, Kathleen L. Gabrielson3, William Matsui4 and Anirban Maitra1,4,5 Cancer Research. 2007 Mar 1;67(5):2187-96 |
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Secoisolariciresinol Diglucoside: Relevance to Angiogenesis and Cardioprotection against Ischemia-Reperfusion Injury
Suresh Varma Penumathsa, Srikanth Koneru, Mahesh Thirunavukkarasu, Lijun Zhan, Kailash Prasad, and Nilanjana Maulik The Journal of Pharmacology and experimental therapeutics. 2007 Feb;320(2):951-9. Epub 2006 Nov 28 |
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Therapy-Induced Acute Recruitment of Circulating Endothelial Progenitor Cells to Tumors
Shaked Y, Ciarrocchi A, Franco M, Lee CR, Man S, Cheung AM, Hicklin DJ, Chaplin D, Foster FS, Benezra R, Kerbel RS. Science. 2006 Sep 22;313(5794):1785-7 |
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The Use of Targeted Mouse Models for Preclinical Testing of Novel Cancer Therapeutics
Kenneth P. Olive and David A. Tuveson Clinical Cancer Research2006 Sept 15; Vol. 12, 5277-5287 |
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Rapamycin improves lymphoproliferative disease in murine autoimmune lymphoproliferative syndrome (ALPS)
David T. Teachey, Dana A. Obzut, Kelly Axsom, John K. Choi, Kelly C. Goldsmith, Junior Hall, Jessica Hulitt, Catherine S. Manno, John M. Maris, Nicholas Rhodin, Kathleen E. Sullivan, Valerie I. Brown, and Stephan A. Grupp Blood. 2006 Sept 15; Vol.108; No.6; 1965-1971. Epub June 6, 2006 |
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Characterization of Digital Waveforms Using Thermodynamic Analogs: Detection of Contrast-Targeted Tissue In Vivo
Michael S. Hughes, Member, IEEE, Jon N. Marsh, Member, IEEE, Hyuing Zhang, Adam K. Woodson, John S. Allen, Elizabeth K. Lacy, Cordelia Carradine, Gregory M. Lanza, and Samuel A. Wickline IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2006 Sep;53(9):1609-16 |
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Oncolytic Viral Therapy By Bladder Instillation Using An E1a, E1b Double-Restricted Adenovirus In An Orthotopic Bladder Cancer Model
Hua Wang, Makoto Satoh, Hisashi Abe, Makoto Sunamura, Takuya Moriya, Shigeto Ishidoya, Seiichi Saito, Hirofumi Hamada, And Yoichi Arai Urology, 2006 Sep;68(3):674-81. Epub 2006 Sep 18 |
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Volume measurement variability in three-dimensional high-frequency ultrasound images of murine liver metastases
Wirtzfeld LA, Graham KC, Groom AC, Macdonald IC, Chambers AF, Fenster A, Lacefield JC. Phys Med Biol. 2006 May 21;51(10):2367-81. Epub 2006 Apr 26. |
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Nanosecond pulsed electric fields cause melanomas to self-destruct
Richard Nuccitellia, bUwe Pliquetta, Xinhua Chena, Wentia Forda, R. James Swansona, Stephen J. Beebea, c, Juergen F. Kolba and Karl H. Schoenbacha Biochem Biophys Res Commun. 2006 May 5;343(2):351-60. Epub 2006 Mar 10 |
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Phospholipase C-{delta}1 Is a Critical Target for Tumor Necrosis Factor Receptor-Mediated Protection against Adriamycin-Induced Cardiac Injury
Lien YC, Noel T, Liu H, Stromberg AJ, Chen KC, St Clair DK. Cancer Res. 2006 Apr 15;66(8):4329-38. |
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Targeted anti-vascular endothelial growth factor receptor-2 therapy leads to short-term and long-term impairment of vascular function and increase in tumor hypoxia
Franco M, Man S, Chen L, Emmenegger U, Shaked Y, Cheung AM, Brown AS, Hicklin DJ, Foster FS, Kerbel RS. Cancer Research. 2006 Apr 1;66(7):3639-48. |
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Validation of Ultrasonography to Evaluate Murine Orthotopic Oral Cavity Tumors
Pezold JC, Zinn K, Talbert MA, Desmond R, Rosenthal EL. ORL J Otorhinolaryngol Relat Spec.2006 Apr; 68(3):159-63. Epub 2006 Feb 6 |
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Fibroblast-derived MT1-MMP promotes tumor progression in vitro and in vivo
Wenyue Zhang, Lynn M Matrisian, Kenn Holmeck, Catherine C Vick and Eben L Rosenthal BMC Cancer2006 March 6; 6:52 |
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Establishment of a serum tumor marker for preclinical trials of mouse prostate cancer models
Huizen IV, Wu G, Moussa M, Chin JL, Fenster A, Lacefield JC, Sakai H, Greenberg NM, Xuan JW Clin Cancer Res. 2005 Nov 1;11(21):7911-9 |
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The use of three-dimensional ultrasound micro-imaging to monitor prostate tumor development in a transgenic prostate cancer mouse model
Wu G, Wang L, Yu L, Wang H, Xuan JW. Tohoku J Exp Med. 2005 Nov;207(3):181-9. |
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Ultrasonic Molecular Imaging of Primordial Angiogenic Vessels in Rabbit and Mouse Models With v3-integrin Targeted Nanoparticles Using Information-Theoretic Signal Detection: Results at High Frequency and in the Clinical Diagnostic Frequency Range
M. Hughes, J. N. Marsh, Jeffrey Arbeit, Robert Neumann,R. W. Fuhrhop, G. M. Lanza, and S. A. Wickline IEEE Ultrasonics Symposium. 2005 Sept 18-21; Vol: 1, PP. 617- 620 |
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Chemopreventive and Therapeutic Efficacy of Orally Active Tyrosine Kinase Inhibitors in a Transgenic Mouse Model of Gallbladder Carcinoma
Kaoru Kiguchi1, Lynnsie Ruffino1, Toru Kawamoto1,2, Tetsuo Ajiki1 and John DiGiovanni1 Clinical Cancer Research2005 Aug 1; Vol. 11, 5572-5580 |
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A new three-dimensional ultrasound microimaging technology for preclinical studies using a transgenic prostate cancer mouse model
Wirtzfeld LA, Wu G, Bygrave M, Yamasaki Y, Sakai H, Moussa M, Izawa JI, Downey DB, Greenberg NM, Fenster A, Xuan JW, Lacefield JC. Cancer Res. 2005 Jul 15;65(14):6337-45. |
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Three-dimensional High-Frequency Ultrasound Imaging for Longitudinal Evaluation of Liver Metastases in Preclinical Models
Graham KC, Wirtzfeld LA, Mackenzie LT, Postenka CO, Groom AC, Macdonald IC, Fenster A, Lacefield JC, Chambers AF. Cancer Research. 2005 Jun 15;65(12):5231-7. |
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Three-dimensional ultrasound biomicroscopy for xenograft growth analysis
Cheung AM, Brown AS, Hastie LA, Cucevic V, Roy M, Lacefield JC, Fenster A, Foster FS. Ultrasound Med Biol. 2005 Jun;31(6):865-870. |
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High-frequency Doppler ultrasound monitors the effects of antivascular therapy on tumor blood flow.
Goertz DE, Yu JL, Kerbel RS, Burns PN, Foster FS. Cancer Research. 2002 Nov 15;62(22):6371-5. |
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Ultrasound Imaging of Apoptosis: DNA-Damage Effects Visualized
Gregory J. Czarnota, Michael C. Kolios, John W. Hunt, Michael D. Sherar Methods in Molecular Biology. 2002 Apr 30; vol. 203, pp. 257-277. |
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Ultrasound backscatter microscope analysis of mouse melanoma progression
Turnbull DH, Ramsay JA, Shivji GS, Bloomfield TS, From L, Sauder DN, Foster FS. Ultrasound Med Biol. 1996 Oct; 22(7):845-53. |
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Applications - Developmental Biology
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Spontaneous Pregnancy Loss Mediated by Abnormal Maternal Inflammation in Rats Is Linked to Deficient Uteroplacental Perfusion
Stephen J. Renaud, Tiziana Cotechini, Jill S. Quirt, Shannyn K. Macdonald-Goodfellow, Maha Othman and Charles H. Graham The Journal of Immunology. 2011 Feb 1;186(3):1799-808. Epub 2010 Dec 27 |
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Regulation of Placental Growth by Aldosterone and Cortisol
Carine Gennari-Moser, Eliyahu V. Khankin, Simone Schüller, Geneviève Escher, Brigitte M. Frey, C.-Bettina Portmann, Marc U. Baumann, Andrea D. Lehmann, Daniel Surbek, S. Ananth Karumanchi, Felix J. Frey, and Markus G. Mohaup Endocrinology.2010 Nov 10. [Epub ahead of print] |
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Inhibition of Trophoblast-Induced Spiral Artery Remodeling Reduces Placental Perfusion in Rat Pregnancy
Stefan Verlohren; Nele Geusens; Jude Morton; Iris Verhaegen; Lydia Hering; Florian Herse; Joachim W. Dudenhausen; Dominik N. Muller; Friedrich C. Luft; Judith E. Cartwright; Sandra T. Davidge; Robert Pijnenborg; and Ralf Dechend Hypertension. 2010 Aug;56(2):304-10. Epub 2010 Jul 6 |
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Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos
Slobodan Beronja1,2, Geulah Livshits1,2, Scott Williams1 & Elaine Fuchs1 Nature Medicine. 2010 Jul;16(7):821-7. Epub 2010 Jun 6 |
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Ventricular Rotation Is Independent of Cardiac Looping: A Study in Mice With Situs Inversus Totalis Using Speckle-Tracking Echocardiography
Lowell H. Frank MDa,c, Qing Yu MDa, Richard Francis PhDa, Xin Tian PhDb, Rajeev Samtania, David J. Sahn MDd, Linda Leatherbury MDa,c and Cecilia W. Lo PhDa,e Journal of the American Society of Echocardiography. 2010 Jan 22. [Epub ahead of print] |
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Developmental Regulation Of Cardiovascular Function Is Dependent On Both Genotype And Environment
Brian S Knight, Nana Sunn, Craig E Pennell, S. Lee Adamson1, and Stephen J Lye2 American Journal of Physiology. Heart and Circulatory Physiology. 2009 Dec;297(6):H2234-41. Epub 2009 Sep 25 |
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Folate rescues lithium-, homocysteine- and Wnt3A-induced vertebrate cardiac anomalies
Mingda Han1, Maria C. Serrano1, Rosana Lastra-Vicente1, Pilar Brinez1, Ganesh Acharya2, James C. Huhta1, Ren Chen3 and Kersti K. Linask1 Disease models & mechanisms. 2009 Sep-Oct;2(9-10):467-78. Epub 2009 Jul 28 |
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Lmo4 and Clim1 Progressively Delineate Cortical Projection Neuron Subtypes during Development
Eiman Azim1,2,3, Sara J. Shnider1,2,3,4, Gustav Y. Cederquist1,2,3, U. Shivraj Sohur1,2,3 and Jeffrey D. Macklis1,2,3 Cerebral Cortex. 2009 Jul;19 Suppl 1:i62-9. Epub 2009 Apr 14 |
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In vivo virtual histology of mouse embryogenesis by ultrasound biomicroscopy and magnetic resonance imaging
P. Pallares 1 , M. E. Fernandez-Valle 2 and A. Gonzalez-Bulnes 3 Reproduction, Fertility and Development. 2009;21(2):283-92 |
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Hypoxia induces dilated cardiomyopathy in the chick embryo: mechanism, intervention, and long-term consequences
Andrei Tintu1,2, Ellen Rouwet3, Stefan Verlohren1,4, Joep Brinkmann1, Shakil Ahmad5, Fatima Crispi6, Marc van Bilsen7, Peter Carmeliet8, Anne Cathrine Staff9, Marc Tjwa10, Irene Cetin11, Eduard Gratacos6, Edgar Hernandez-Andrade6, Leo Hofstra12, Michael Jacobs2, Wouter H. Lamers13, Ingo Morano14, Erdal Safak15, Asif Ahmed5, Ferdinand le Noble1 PloS One. 2009;4(4):e5155. Epub 2009 Apr 9 |
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Embryonic caffeine exposure induces adverse effects in adulthood
Christopher C. Wendler, Melissa Busovsky-McNeal, Satish Ghatpande, April Kalinowski, Kerry S. Russell, and Scott A. Rivkees The FASEB Journal. 2009 Apr;23(4):1272-8. Epub 2008 Dec 16 |
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Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis
Jing Gao, Mindy C. DeRouen, Chih-Hsin Chen, Michael Nguyen, Ngon T. Nguyen, Hiroyuki Ido, Kenji Harada, Kiyotoshi Sekiguchi, Bruce A. Morgan, Jeffery H. Miner, Anthony E. Oro, and M. Peter Marinkovich Genes & Development. 2008 Aug 1; 22(15):2111-24 |
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Transcriptional coactivators PGC-1{alpha} and PGC-1{beta} control overlapping programs required for perinatal maturation of the heart
Ling Lai, Teresa C. Leone, Christoph Zechner, Paul J. Schaeffer, Sean M. Kelly, Daniel P. Flanagan, Denis M. Medeiros, Attila Kovacs, and Daniel P. Kelly Genes & Development. 2008 Jul 15;22(14):1948-61 |
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Cystic Adenomatoid Malformations Are Induced by Localized FGF10 Overexpression in Fetal Rat Lung
Sílvia Gonzaga, Tiago Henriques-Coelho, Marcus Davey, Philip W. Zoltick, Adelino F. Leite-Moreira, Jorge Correia-Pinto and Alan W. Flake American Journal of Respiratory Cell and Molecular Biology. 2008 Apr 17, Vol. 39, pp. 346-355, 2008 |
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Regulation of Maternal and Fetal Hemodynamics by Heme Oxygenase in Mice
Hui Zhao, Ronald J. Wong, Timothy C. Doyle, Nihar Nayak, Hendrik J. Vreman, Christopher H. Contag, and David K. Stevenson Biology of Reproduction. 2008 Apr;78(4):744-51. Epub 2007 Dec 19 |
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Ultrasound-guided in utero injections allow studies of the development and function of the eye
Claudio Punzo and Constance L. Cepko Developmental dynamics. 2008 Apr;237(4):1034-42 |
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Enhancing Repair of the Mammalian Heart
Maria Paola Santini, Lana Tsao, Laurent Monassier, Catherine Theodoropoulos, Janice Carter, Enrique Lara-Pezzi, Esfir Slonimsky, Ekaterina Salimova, Patrice Delafontaine, Yao-Hua Song, Martin Bergmann, Christian Freund, Ken Suzuki, and Nadia Rosenthal Circ. Res.2007 Jun 22;100(12):1732-40. Epub 2007 May 24 |
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Transitions in Early Embryonic Atrioventricular Valvular Function Correspond With Changes in Cushion Biomechanics That Are Predictable by Tissue Composition
Jonathan T. Butcher, Tim C. McQuinn, David Sedmera, Debi Turner, Roger R. Markwald Circulation Research. 2007 May 25;100(10):1503-11. Epub 2007 May 3 |
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Fgl2 deficiency causes neonatal death and cardiac dysfunction during embryonic and postnatal development in mice
Junwu Mu, Dawei Qu, Agata Bartczak, M. James Phillips, Justin Manuel, Wei He, Cheryl Koscik, Michael Mendicino, Li Zhang, David A. Clark, David R. Grant, Peter H. Backx, Gary A. Levy, and S. Lee Adamson Physiol. Genomics. 2007 Sept; 31(1): 53-62, Epub 2007 Jun 5 |
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Increased Ventricular Preload Is Compensated by Myocyte Proliferation in Normal and Hypoplastic Fetal Chick Left Ventricle
deAlmeida A, McQuinn T, Sedmera D. Circulation Research. 2007 May 11; Circ. Res. 2007 100: 1246-1248; Epub 2007 Apr 5 |
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Cardiovascular Developmental Insights from Embryos
BRADLEY B. KELLER, LI J. LIU, JOSEPH P. TINNEY AND KIMIMASA TOBITA Ann N Y Acad Sci. 2007 Apr;1101:377-88. Epub 2007 Feb 15. |
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Initial Experience with High Frequency Ultrasound for the Newborn C57BL Mouse
Alok K. Bose, M.D.*, James W. Mathewson, M.D.*, Brent E. Anderson, B.S.†, Allyson M. Andrews, B.A.*, A. Martin Gerdes, Ph.D.†, M. Benjamin Perryman, Ph.D.† and Paul D. Grossfeld, M.D.* Echocardiography. 2007 Apr; Vol 24, Issue 4, PP. 412-419 |
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3D Visualisation and Quantification by Microcomputed Tomography of Late Gestational Changes in the Arterial and Venous Feto-Placental Vasculature of the Mouse
M.Y. Rennie a, K.J. Whiteley b, S. Kulandavelu b,c, S.L. Adamson b,c, J.G. Sled Placenta. 2007 Aug-Sept; 28(8-9), PP 833-840; Epub 2007 Feb 23 |
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Sequential Alterations of Tracheal Mechanical Properties in the Neonatal Lamb: Effect of Mechanical Ventilation
Thomas L. Miller, PhD, Yan Zhu, MD, Allison R. Altman, BS,Kevin Dysart, MD and Thomas H. Shaffer, PhD Pediatric Pulmonology2007 Feb; 42(2), PP 141–149 |
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Fetal mouse imaging using echocardiography: a review of current technology
Spurney CF, Lo CW, Leatherbury L. Echocardiography. 2006 Nov;23(10):891-9 |
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Developmental changes in hemodynamics of uterine artery, utero- and umbilicoplacental, and vitelline circulations in mouse throughout gestation
Junwu Mu1,2,3 and S. Lee Adamson1,2,3 American journal of physiology. Heart and circulatory physiology. 2006 Sep;291(3):H1421-8. Epub 2006 Apr 7 |
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Imaging Tools for the Developmental Biologist: Ultrasound Biomicroscopy of Mouse Embryonic Development
Phoon CK. Pediatric Research. 2006 Jul;60(1):14-21. Epub 2006 May 11 |
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Layer acquisition by cortical GABAergic interneurons is independent of Reelin signaling
Pla R, Borrell V, Flames N, Marin O. J Neurosci. 2006 Jun 28;26(26):6924-34. |
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Cardiovascular Function in Mice During Normal Pregnancy and in the Absence of Endothelial NO Synthase
Kulandavelu S, Qu D, Adamson SL. Hypertension. 2006 Jun;47(6):1175-82. Epub 2006 Apr 24 |
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Embryonic and Neonatal Phenotyping of Genetically Engineered Mice
Shathiyah Kulandavelu, Dawei Qu, Nana Sunn, Junwu Mu, Monique Y. Rennie, Kathie J. Whiteley, Johnathon R. Walls, Nicholas A. Bock, John C. H. Sun, Andrea Covelli, John G. Sled, and S. Lee Adamson ILAR Journal, 2006 Mar; 47(2):103-17 |
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High resolution ultrasound-guided microinjection for interventional studies of early embryonic and placental development in vivo in mice
John C. Slevin, Lois Byers, Marina Gertsenstein, Dawei Qu, Junwu Mu, Nana Sunn, John C.P. Kingdom, Janet Rossant and S. Lee Adamson BMC Developmental Biology,2006 Feb 27; 6:10 |
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Noninvasive Localization of Nuclear Factor of Activated T Cells c1-/- Mouse Embryos by Ultrasound Biomicroscopy-Doppler Allows Genotype-phenotype Correlation
Ji RP, Phoon CK. J Am Soc Echocardiogr. 2005 Dec;18(12):1415-21 |
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A Gja1 missense mutation in a mouse model of oculodentodigital Dysplasia
Ann M. Flenniken1,*, Lucy R. Osborne1,2,3,*, Nicole Anderson4, Nadia Ciliberti5, Craig Fleming1, Joanne E. I. Gittens6, Xiang-Qun Gong6, Lois B. Kelsey1, Crystal Lounsbury7, Luisa Moreno8, Brian J. Nieman9,10, Katie Peterson1, Dawei Qu8, Wendi Roscoe7, Qing Shao7, Dan Tong6, Gregory I. L. Veitch6,7, Irina Voronina1, Igor Vukobradovic1, Geoffrey A. Wood1, Yonghong Zhu11, Ralph A. Zirngibl3, Jane E. Aubin1,3, Donglin Bai6, Benoit G. Bruneau3,11,12, Marc Grynpas1,13, Janet E. Henderson14, R. Mark Henkelman9,10, Colin McKerlie1,13,15, John G. Sled9,10, William L. Stanford1,4,5, Dale W. Laird6,7, Gerald M. Kidder6, S. Lee Adamson1,12,16 and Janet Rossant1,3,† Development, 2005 Oct;132(19):4375-86 |
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Developmental structure-function insights from Tbx5del/+ mouse model of Holt-Oram syndrome
Keller, BB. Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H975-6. |
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Abnormal cardiac inflow patterns during postnatal development in a mouse model of Holt-Oram syndrome
Zhou YQ, Zhu Y, Bishop J, Davidson L, Henkelman RM, Bruneau BG, and Foster FS. Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H992-H1001. Epub 2005 Apr 22 |
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Quantitation of Hemodynamic Function during Developmental Vascular Regression in the Mouse Eye
Brown AS, Leamen L, Cucevic V, Foster FS Invest Ophthalmol Vis Sci. 2005 Jul;46(7):2231-7. |
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Arterial hemodynamics and mechanical properties after circulatory intervention in the chick embryo
Tang YD, Kuzman JA, Said S, Anderson BE, Wang X, Gerdes AM. Circulation. 2005 May;208(Pt 10):1877-85 |
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Ultrasonic detection and developmental changes in calcification of the placenta during normal pregnancy in mice
Akirav C, Lu Y, Mu J, Qu DW, Zhou YQ, Slevin J, Holmyard D, Foster FS, Adamson SL. Placenta. 2005 Feb-Mar;26(2-3):129-37. |
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In Vivo Assessment of Postnatal Murine Ocular Development by Ultrasound Biomicroscopy
Allison S. Brown A1, MingYu Zhang A1, Viviene Cucevic A1, Charles J. Pavlin A2, F. Stuart Foster A3 Current Eye Research, 2005 Jan;30(1):45-51 |
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TGF-beta-dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome
Connie M. Ng, Alan Cheng, Loretha A. Myers, Francisco Martinez-Murillo, Chunfa Jie, Djahida Bedja, Kathleen L. Gabrielson, Jennifer M.W. Hausladen, Robert P. Mecham, Daniel P. Judge, Harry C. Dietz Journal of Clinical Investigation. 2004 Dec 1 ; 114(11): 1586-1592 |
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Baf60c is essential for function of BAF chromatin remodelling complexes in heart development
HEIKO LICKERT, JUN K. TAKEUCHI, INGO VON BOTH, JOHNATHON R. WALLS, FIONNUALA MCAULIFFE, S. LEE ADAMSON, R. MARK HENKELMAN, JEFFREY L. WRAN, JANET ROSSANT & BENOIT G. BRUNEAU Nature2004 Nov 4;432(7013):107-12 |
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Developmental changes in integrated ultrasound backscatter from embryonic blood in vivo in mice at high US frequency
Le Floc'h J, Cherin E, Zhang MY, Akirav C, Adamson SL, Vray D, Foster FS. Ultrasound Med Biol. 2004 Oct;30(10):1307-19. |
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Biological effects of high-frequency ultrasound exposure during mouse organogenesis
Allison S. Brown*, Angela D. Reid*, Lisa Leamen*, Viviene Cucevic* and F. Stuart Foster*, † Ultrasound Med Biol. 2004 Sep;30(9):1223-32 |
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Developmental changes in left and right ventricular diastolic filling patterns in mice
Yu-Qing Zhou1, F. Stuart Foster2, Robert Parkes3, and S. Lee Adamson4 American Journal of Physiology. Heart and Circulatory Physiology. 2003 Oct;285(4):H1563-75. Epub 2003 Jun 12 |
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In vivo imaging of embryonic development in the mouse eye by ultrasound biomicroscopy
Foster FS, Zhang M, Duckett AS, Cucevic V, Pavlin CJ. Investigative Ophthalmology & Visual Science. 2003 Jun;44(6):2361-6. |
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Applications for multifrequency ultrasound biomicroscopy in mice from implantation to adulthood
Zhou YQ, Foster FS, Qu DW, Zhang M, Harasiewicz KA, Adamson SL. Physiol Genomics. 2002 Aug 14;10(2):113-26. |
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In vivo ultrasound biomicroscopy in developmental biology
Daniel H. Turnbull, F. Stuart Foster Trends in Biotechnology. 2002 Aug 1;20(8):S29-33. |
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40-MHZ echocardiography scanner for cardiovascular assessment of mouse embryos
Aristizabal O, Christopher DA, Foster FS, Turnbull DH. Ultrasound Med Biol. 1998 Nov;24(9):1407-17. |
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Ultrasound backscatter microscope analysis of early mouse embryonic brain development
Turnbull DH, Bloomfield TS, Baldwin HS, Foster FS, Joyner AL. Proc Natl Acad Sci U S A. 1995 Mar 14;92(6):2239-43. |
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Applications - Neurobiology
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Neuregulin-1 potentiates agrin-induced acetylcholine receptor clustering through muscle-specific kinase phosphorylation
Shyuan T. Ngo1, Rebecca N. Cole3, Nana Sunn2, William D. Phillips3, and Peter G. Noakes1,2 Journal of Cell Science. 2012 Feb 10. [Epub ahead of print] |
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Laforin and malin knockout mice have normal glucose disposal and insulin sensitivity
Anna A. DePaoli-Roach1, Dyann M. Segvich1, Catalina M. Meyer1, Yasmeen Rahimi1, Carolyn A. Worby2, Matthew S. Gentry3 and Peter J. Roach1 Human Molecular Genetics. 2012 Jan 4. [Epub ahead of print] |
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Peripheral Nervous System Progenitors Can Be Reprogrammed to Produce Myelinating Oligodendrocytes and Repair Brain Lesions
Ellen Binder1, Marion Rukavina2, Hessameh Hassani3, Marlen Weber1, Hiroko Nakatani3, Tobias Reiff1, Carlos Parras3, Verdon Taylor2,4, and Hermann Rohrer1 The Journal of Neuroscience. 2011 Apr 27;31(17):6379-6391 |
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In Vivo Imaging of Cerebral Hemodynamics Using High-Frequency Micro-Ultrasound
John Sun1, Liis Lindvere1,2, Martijn E. van Raaij1, Adrienne Dorr1, Bojana Stefanovic1,2, and F. Stuart Foster1,2 Cold Spring Harbor Protocols. 2010 Sep 1;2010(9):pdb.prot5495 |
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Ultrasound Imaging of Regenerating Rat Sciatic Nerves In Situ
Damien P. Kuffler Journal of Neuroscience Methods. 2010 Mar 6. [Epub ahead of print] |
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Origin and Molecular Specification of Globus Pallidus Neurons
Sandrina N�brega-Pereira1,2, Diego Gelman1, Giorgia Bartolini1, Ram�n Pla1, Alessandra Pierani3 and Oscar Mar�n1 The Journal of Neuroscience. 2010 Feb 24;30(8):2824-34 |
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Area-specific temporal control of corticospinal motor neuron differentiation by COUP-TFI
Giulio Srubek Tomassy1, Elvira De Leonibus1,2, Denis Jabaudon3,4, Simona Lodato1, Christian Alfano1, Andrea Mele2, Jeffrey D. Macklis3, and Mich�le Studer1,5 Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2010 Feb 23;107(8):3576-3581. Epub 2010 Feb 2 |
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Paracrine Regulation of Pancreatic Cancer Cell Invasion by Peripheral Nerves
Ziv Gil, Oren Cavel, Kaitlyn Kelly, Peter Brader, Avigail Rein, Sizhi P. Gao, Diane L. Carlson, Jatin P. Shah, Yuman Fong, Richard J. Wong Journal of the National Cancer Institute. 2010 Jan 12. [Epub ahead of print] |
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Novel subtype-specific genes identify distinct subpopulations of callosal projection neurons
Bradley J. Molyneaux, Paola Arlotta, Ryann M. Fame, Jessica L. MacDonald, Kyle L. MacQuarrie and Jeffrey D. Macklis The Journal of Neuroscience. 2009 Sep 30;29(39):12343-54 |
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High-resolution ultrasonography of the cutaneous nerve branches in the hand and wrist
A Stokvis, J W van Neck, C F van Dijke, A van Wamel, and J H Coert Journal of Hand Surgery (European Volume). 2009 Dec;34(6):766-71. Epub 2009 Sep 28 |
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Lmo4 and Clim1 Progressively Delineate Cortical Projection Neuron Subtypes during Development
Eiman Azim1,2,3, Sara J. Shnider1,2,3,4, Gustav Y. Cederquist1,2,3, U. Shivraj Sohur1,2,3 and Jeffrey D. Macklis1,2,3 Cerebral Cortex. 2009 Jul;19 Suppl 1:i62-9. Epub 2009 Apr 14 |
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Early-Life Sodium Exposure Unmasks Susceptibility to Stroke in Hyperlipidemic, Hypertensive Heterozygous Tg25 Rats Transgenic for Human Cholesteryl Ester Transfer Protein
Julius L. Decano MD, Jason C. Viereck MD, PhD, Ann C. McKee MD, James A. Hamilton PhD, Nelson Ruiz-Opazo PhD, and Victoria L.M. Herrera MD Circulation. 2009 Mar 24;119(11):1501-9. Epub 2009 Mar 9 |
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Neural progenitors of the postnatal and adult mouse forebrain retain the ability to self-replicate, form neurospheres and undergo multipotent differentiation in vivo
Bettina Neumeister, Antje Grabosch, Onur Basak, Rolf Kemler and Verdon Taylor Stem Cells (Dayton, Ohio). 2009 Mar;27(3):714-23: 2008 Dec 18. [Epub ahead of print] |
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Chemokine Signaling Controls Intracortical Migration and Final Distribution of GABAergic Interneurons
Guillermina Lopez-Bendito, Juan Antonio Sánchez-Alcañiz, Ramón Pla, Víctor Borrell, Esther Picó, Miguel Valdeolmillos, and Oscar Marín The Journal of Neuroscience. 2008 Feb 13;28(7):1613-24 |
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Delineation of Multiple Subpallial Progenitor Domains by the Combinatorial Expression of Transcriptional Codes
Nuria Flames,1 Ramón Pla,1 * Diego M. Gelman,1 * John L. R. Rubenstein,2 Luis Puelles,3,4 and Oscar Marín1 The Journal of Neuroscience. 2007 Sep 5;27(36):9682-95 |
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Layer acquisition by cortical GABAergic interneurons is independent of Reelin signaling
Pla R, Borrell V, Flames N, Marin O. J Neurosci. 2006 Jun 28;26(26):6924-34. |
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Fezl is required for the birth and specification of corticospinal motor neurons
Molyneaux BJ, Arlotta P, Hirata T, Hibi M, Macklis JD Neuron. 2005 Sep 15;47(6):817-31 |
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Neuronal Subtype-Specific Genes that Control Corticospinal Motor Neuron Development In Vivo
Paola Arlotta1,3, Bradley J. Molyneaux1, 3, Jinhui Chen1, 4, Jun Inoue2, Ryo Kominami2 and Jeffrey D. Macklis, 1 Neuron. 2005 Jan 20; Vol 45, Issue 2, PP. 207-221 |
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Transgenic rescue of neurogenic atrophy in the nmd mouse reveals a role for Ighmbp2 in dilated cardiomyopathy
Terry P. Maddatu, Sean M. Garvey, David G. Schroeder, Thomas G. Hampton and Gregory A. Cox Human Molecular Genetics2004 Jun 1;13(11):1105-15. Epub 2004 Apr 6 |
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Ultrasound backscatter microscope analysis of early mouse embryonic brain development
Turnbull DH, Bloomfield TS, Baldwin HS, Foster FS, Joyner AL. Proc Natl Acad Sci U S A. 1995 Mar 14;92(6):2239-43. |
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Applications - Cell Death
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Dysferlin Deficiency and the Development of Cardiomyopathy in a Mouse Model of Limb-Girdle Muscular Dystrophy 2B
Thomas H. Chase, Gregory A. Cox, Lisa Burzenski, Oded Foreman and Leonard D. Shultz The American Journal of Pathology. 2009 Dec;175(6):2299-308. Epub 2009 Oct 29 |
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Quantitative Ultrasound Characterization of Responses to Radiotherapy in Cancer Mouse Models
Roxana M. Vlad 1, 3, Sebastian Brand 5, Anoja Giles 3, Michael C. Kolios 1, 4, Gregory J. Czarnota 1, 2, 3 Clinical Cancer Research. 2009 Mar 15;15(6):2067-75. Epub 2009 Mar 10 |
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Imaging Hypoxia in Orthotopic Rat Liver Tumors with Iodine 124-labeled Iodoazomycin Galactopyranoside PET
Christopher C. Riedl,MD; Peter Brader,MD; Pat B. Zanzonico, PhD; Yun Shin Chun,MD; Yanghee Woo, MD; Paramjeet Singh, MD; Sean Carlin, PhD; Bixiu Wen,MD; C. Clifton Ling, PhD; Hedvig Hricak,MD; Yuman Fong, MD Radiology. 2008 Aug;248(2):561-70 |
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Vitamin E analogues inhibit angiogenesis by selective induction of apoptosis in proliferating endothelial cells: the role of oxidative stress
Lan-Feng Dong, Emma Swettenham, Johanna Eliasson, Xiu-Fang Wang, Mikhal Gold, Yasmine Medunic, Marina Stantic, Pauline Low, LubomirPr ochazka, Paul K. Witting, Jaroslav Turanek, Emmanuel T. Akporiaye, Stephen J. Ralph, and Jiri Neuzil Cancer Research. 2007 Dec 15;67(24):11906-13. |
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Ultrasonic characterization of whole cells and isolated nuclei
Taggart LR, Baddour RE, Giles A, Czarnota GJ, Kolios MC. Ultrasound Med Biol. 2007 Mar;33(3):389-401 |
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The fluid and elastic nature of nucleated cells: Implications from the cellular backscatter response
Ralph E. Baddour and Michael C. Kolios Journal of the Acoustical Society of America. 2007 Jan; 121(1): EL16-EL22; Epub 2006 Dec 8 |
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Monitoring Structural Changes In Cells With High-frequency Ultrasound Signal Statistics
A. S. Tunis,*‡ G. J. Czarnota,†‡§ A. Giles‡ M. D. Sherar,*†‡_ J. W. Hunt,*‡ And M. C. Kolios* Ultrasound in Med. & Biol.,2005 Aug;31(8):1041-9 |
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High-frequency ultrasound scattering from microspheres and single cells
R. E. Baddour1, M. D. Sherar1, J. W. Hunt1, G. J. Czarnota2, and M. C. Kolios3 The Journal of the Acoustical Society of America. 2005 Feb; 117(2): 934-943 |
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Applications - Additional Applications
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Lipid phosphate phosphatase 3 enables efficient thymic egress
Béatrice Bréart1, Willy D. Ramos-Perez1, Alejandra Mendoza1, Abdelghaffar K. Salous2, Michael Gobert1, Yong Huang3, Ralf H. Adams4,5, Juan J. Lafaille1, Diana Escalante-Alcalde6, Andrew J. Morris2, and Susan R. Schwab1 The Journal of Experimental Medicine. 2011 Jun 6;208(6):1267-78. Epub 2011 May 16 |
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Tendon adhesion measured by a video-assisted gliding test in a chicken model
S.-C. Fu, L.-K. Hung, Y.-W. Lee, T.-Y. Mok, K.-M. Chan The Journal of Hand Surgery (European Volume). 2011 Jan;36(1):40-7. Epub 2010 Sep 3 |
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Nonlinear contrast imaging with an array-based micro-ultrasound system
Needles A, Arditi M, Rognin NG, Mehi J, Coulthard T, Bilan-Tracey C, Gaud E, Frinking P, Hirson D, Foster FS Ultrasound in Medicine and Biology. 2010 Dec;36(12):2097-106. |
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High-Throughput Doppler Toolbox for Preclinical Drug Development
Karim Azer1, Michael C. Desiderio1, Christopher Tong2, Michelle Bunzel3, Barry R. Campbell3, Diane Shevell4, Matthew Walker III3 Journal of the Association for Laboratory Automation (JALA). 2010 Aug; vol.15 issue 4, 287-296 |
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Ultrasound-assisted non-viral gene transfer to the salivary glands
Michael J Passineau PhD1, Lee Zourelias1, Laurie Machen BS1, Paul C Edwards DDS2, and Raymond L Benza MD1 Gene Therapy. 2010 May 27. [Epub ahead of print] |
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Morphological study of acoustic liposomes using transmission electron microscopy
Tetsuya Kodama1, Noriko Tomita1, Sachiko Horie1, Nicolas Sax1, Hiroko Iwasaki1, Ryo Suzuki2, Kazuo Maruyama2, Shiro Mori3 and Fukumoto Manabu4 Journal of Electron Microscopy. 2010;59(3):187-96. Epub 2009 Nov 11 |
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Comparison of gene delivery techniques for therapeutic angiogenesis ultrasound-mediated destruction of carrier microbubbles versus direct intramuscular injection
Jeremy Kobulnik, Michael A. Kuliszewski, Duncan J. Stewart, Jonathan R. Lindner, and Howard Leong-Poi Journal of the American College of Cardiology (JACC). 2009 Oct 27;54(18):1735-42 |
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iPS Programmed Without c-MYC Yield Proficient Cardiogenesis for Functional Heart Chimerism
Almudena Martinez-Fernandez ; Timothy J. Nelson ; Satsuki Yamada ; Santiago Reyes ; Alexey E. Alekseev ; Carmen Perez-Terzic ; Yasuhiro Ikeda ; and Andre Terzic Circulation Research. 2009 Sep 25;105(7):648-56. Epub 2009 Aug 20 |
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Paired Box Gene 8-Peroxisome Proliferator-Activated Receptor-γ Fusion Protein and Loss of Phosphatase and Tensin Homolog Synergistically Cause Thyroid Hyperplasia in Transgenic Mice
Ericka Diallo-Krou, Jingcheng Yu, Lesley A. Colby, Ken Inoki, John E. Wilkinson, Dafydd G. Thomas, Thomas J. Giordano, and Ronald J. Koenig Endocrinology. 2009 Nov;150(11):5181-90. Epub 2009 Sep 24 |
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Efficient Regulation of VEGF Expression by Promoter-Targeted Lentiviral shRNAs Based on Epigenetic Mechanism. A Novel Example of Epigenetherapy
Mikko P. Turunen ; Tiia Lehtola ; Suvi E. Heinonen ; Genet S. Assefa ; Petra Korpisalo ; Roseanne Girnary ; Christopher K. Glass ; Sami Väisänen ; and Seppo Ylä-Herttuala Circulation Research. 2009 Sep 11;105(6):604-9. Epub 2009 Aug 20 |
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High-Frequency Ultrasound to Grade Disease Progression in Murine Models of Duchenne Muscular Dystrophy
Nabeel Ahmad, MSc, Mike Bygrave, BSc, Rethy Chhem, MD, PhD, Lisa Hoffman, PhD, Ian Welch, DVM, Robert Grange, PhD, Aaron Fenster, PhD, David Hill, PhD and Ting-Yim Lee, PhD Journal of ultrasound in medicine. 2009 Jun;28(6):707-16 |
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Induction of factor VIII-specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia A
S. Madoiwa1; T. Yamauchi; E. Kobayashi2; Y. Hakamata2; M. Dokai1; N. Makino1; Y. Kashiwakura1; A. Ishiwata1; T. Ohmori1; J. Mimuro1; Y. Sakata1 Journal of Thrombosis and Haemostasis. 2009 May;7(5):811-24. Epub 2009 Feb 12 |
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Ultrasound and Doppler micro-imaging in a model of rheumatoid arthritis in mice
Gaëlle Clavel 1, Carmen Marchiol-Founigault 2, Gilles Renault 2, Marie-Christophe Boissier 2, Didier Fradelizi 2 and Natacha Bessis 2* Annals of the Rheumatic Diseases. 2008 Dec; 67: 1765 - 1772 |
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Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis
Jing Gao, Mindy C. DeRouen, Chih-Hsin Chen, Michael Nguyen, Ngon T. Nguyen, Hiroyuki Ido, Kenji Harada, Kiyotoshi Sekiguchi, Bruce A. Morgan, Jeffery H. Miner, Anthony E. Oro, and M. Peter Marinkovich Genes & Development. 2008 Aug 1; 22(15):2111-24 |
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Experimental autoimmune prostatitis induces chronic pelvic pain
Rudick CN, Schaeffer AJ, Thumbikat P American Journal of Physiology, Regulatory, Integrative and Comparative Physiology. 2008 Apr;294(4):R1268-75. |
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Targeting Notch signaling in autoimmune and lymphoproliferative disease
David T Teachey, Alix E Seif, Valerie I. Brown, Marlo Bruno, Ralph M Bunte, Yueh J Chang, John K Choi, Jonathan D Fish, Junior Hall, Gregor S Reid, Theresa Ryan, Cecilia Sheen, Patrick Zweidler-McKay, and Stephan A. Grupp Blood. 2008 Jan 15;111(2):705-14. |
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Inhibition of N-Ethylmaleimide-Sensitive Factor Protects Against Myocardial Ischemia/Reperfusion Injury
John W. Calvert, Susheel Gundewar, Munekazu Yamakuchi, Pierce C. Park, William M. Baldwin III, David J. Lefer, Charles J. Lowenstein Circ Res. 2007 Dec 7;101(12):1247-54; Epub 2007 Oct 11 |
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Sensitive ultrasonic delineation of steroid treatment in living dystrophic mice with energy-based and entropy-based radio frequency signal processing
Wallace KD, Marsh JN, Baldwin SL, Connolly AM, Keeling R, Lanza GM, Wickline SA, Hughes MS. IEEE Trans Ultrason Ferroelectr Freq Control. 2007 Nov;54(11):2291-9. |
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Multispectral photoacoustic imaging of fluorochromes in small animals
Daniel Razansky, Claudio Vinegoni, and Vasilis Ntziachristos Optics Letters,2007 Oct 1;32(19):2891-3 |
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Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection
Noma T, Lemaire A, Naga Prasad SV, Barki-Harrington L, Tilley DG, Chen J, Le Corvoisier P, Violin JD, Wei H, Lefkowitz RJ, Rockman HA. J Clin Invest. 2007 Sep 4;117(9):2445-58 |
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High frequency ultrasound imaging of a single-species biofilm
H. Shemesh, D.E. Goertz, L.W.M. van der Sluis, N. de Jong, M.K. Wu and P.R. Wesselink Journal of Dentistry,2007 Aug; 35(8):673-8. Epub 2007 Jul 2 |
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Morphological differences between guinea pig aortic and venous endothelial cells in situ
Kazuo Katoh, Yumiko Kano, Shigeo Ookawara Cell Biology International. 2007 Jun;31(6):554-64. Epub 2006 Dec 3 |
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Adhesion is prerequisite, but alone insufficient, to elicit stem cell pluripotency
Phillip Karpowicz,1 Tomoyuki Inoue,2 Sue Runciman,2 Brian Deveale,2 Raewyn Seaberg,2 Marina Gertsenstein,3 Lois Byers,3 Yojiro Yamanaka,3 Sandra Tondat,3 John Slevin,3 Seiji Hitoshi,4 Janet Rossant,3 and Derek van der Kooy2 The Journal of Neuroscience. 2007 May 16;27(20):5437-47 |
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An ultrasound imaging method for in vivo tracheal bulk and Young's moduli of elasticity
Miller TL, Altman AR, Tsuda T, Shaffer TH. J Biomech. 2007 May;40(7):1615-21. Epub 2006 Oct 11. |
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Sequential Alterations of Tracheal Mechanical Properties in the Neonatal Lamb: Effect of Mechanical Ventilation
Thomas L. Miller, PhD, Yan Zhu, MD, Allison R. Altman, BS,Kevin Dysart, MD and Thomas H. Shaffer, PhD Pediatric Pulmonology2007 Feb; 42(2), PP 141–149 |
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Excitation of polymer-shelled contrast agents with high-frequency ultrasound
Ketterling JA, Mamou J, Allen JS 3rd, Aristizábal O, Williamson RG, Turnbull DH. J Acoust Soc Am. 2007 Jan;121(1):EL48-53. |
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High-Resolution Ultrasound Elastography of Articular Cartilage in Vitro
Daniel T. Ginat MD, Gilberto Hung BS, Thomas R. Gardner MCE and Elisa E. Konofagou PhD 28th Annual International Conference of the Engineering in Medicine and Biology Society (EMBS)2006 Aug 30 - Sept 06; Supplement: PP 6644 - 6647 |
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Vascularized organoid engineered by modular assembly enables blood perfusion
Alison P. McGuigan and Michael V. Sefton PNAS. 2006 Aug 1;103(31):11461-6. Epub 2006 Jul 24 |
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Validation of a 40 MHz B-scan ultrasound biomicroscope for the evaluation of osteoarthritis lesions in an animal model
Spriet MP, Girard CA, Foster SF, Harasiewicz K, Holdsworth DW, Laverty S. Osteoarthritis Cartilage. 2005 Feb;13(2):171-9. |
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Thermal assessment of 40-MHz ultrasound at soft tissue-bone interfaces
AS Duckett , AD Reid, L Leamen , V Cucevic , FS Foster Ultrasound Med Biol. 2004 May;30(5):665-73. |
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Applications for multifrequency ultrasound biomicroscopy in mice from implantation to adulthood
Zhou YQ, Foster FS, Qu DW, Zhang M, Harasiewicz KA, Adamson SL. Physiol Genomics. 2002 Aug 14;10(2):113-26. |
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Challenges in Small Animal Noninvasive Imaging
Balaban, R. and V. Hampshire ILAR Journal2001 Jul; 42(3): 248-263 |
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Ultrasound Imaging: Principles and Applications in Rodent Research
Coatney, R. et al. ILAR Journal2001 Jul; 42(3): 233-247. |
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Techniques - Overviews and Multi-Modality Imaging
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Evaluation of imaging technologies to correct for photon attenuation in the overlying tissue for in vivo bone strontium measurements
C M Heirwegh1,3, D R Chettle1 and A Pejović-Milić1,2 Physics in Medicine and Biology. 2010 Feb 21;55(4):1083-98. Epub 2010 Jan 28 |
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Micro-Positron Emission Tomography in the Evaluation of Trypanosoma cruzi-Induced Heart Disease: Comparison with Other Modalities
Cibele M. Prado, Eugene J. Fine, Wade Koba, Dazhi Zhao, Marcos A. Rossi, Herbert B. Tanowitz, and Linda A. Jelicks The American Journal of Tropical Medicine and Hygiene. 2009 Nov;81(5):900-5 |
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Feasibility of Functional Cardiac MR Imaging in Mice Using A Clinical 3 Tesla Whole Body Scanner
Alexander C Bunck, Markus A Engelen, Bernhard Schnackenburg, Juliane Furkert, Christoph Bremer, Walter Heindel, Jorg Stypmann, and David Maintz Investigative Radiology. 2009 Oct 15. [Epub ahead of print] |
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In vivo, Noninvasive, Label-Free Detection and Eradication of Circulating Metastatic Melanoma Cells Using Two-Color Photoacoustic Flow Cytometry with a Diode Laser
Ekaterina I. Galanzha 1, 2, Evgeny V. Shashkov 1, Paul M. Spring 2, James Y. Suen 2, and Vladimir P. Zharov 1, 2 Cancer Research. 2009 Oct 15;69(20):7926-34. Epub 2009 Oct 13 |
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A new 15-50 MHz array-based micro-ultrasound scanner for preclinical imaging
F. Stuart Foster1, James Mehi2, Marc Lukacs1, Desmond Hirson2, Chris White2, Chris Chaggares2 and Andrew Needles2 Ultrasound in Medicine & Biology. 2009 Oct;35(10):1700-8. Epub 2009 Aug 3 |
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Complementarity of ultrasound and fluorescence imaging in an orthotopic mouse model of pancreatic cancer
Cynthia S Snyder1 , Sharmeela Kaushal1 , Yuko Kono2 , Hop S Tran Cao3 , Robert M Hoffman3,4 and Michael Bouvet1,3 BMC Cancer. 2009 Apr 8;9(1):106. [Epub ahead of print] |
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Left Ventricular Functional Assessment in Mice: Feasibility of High Spatial and Temporal Resolution ECG-gated Blood Pool SPECT
Bennett B. Chin, MD, Scott D. Metzler, PhD, Anthony Lemaire, MD, Antonio Curcio, MD, Sreekanth Vemulapalli, BS, Kim L. Greer, CNMT, Neil A. Petry, MS, Timothy G. Turkington, PhD, R. Edward Coleman, MD, Howard Rockman, MD, and Ronald J. Jaszczak, PhD Radiology. 2007 Nov;245(2):440-8 |
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Multispectral photoacoustic imaging of fluorochromes in small animals
Daniel Razansky, Claudio Vinegoni, and Vasilis Ntziachristos Optics Letters,2007 Oct 1;32(19):2891-3 |
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Anatomical phenotyping in the brain and skull of a mutant mouse by magnetic resonance imaging and computed tomography
Brian J. Nieman1,2, Ann M. Flenniken3, S. Lee Adamson3,4, R. Mark Henkelman1,2 and John G. Sled1,2 Physiological Genomics. 2006 Jan 12;24(2):154-62 |
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Fast spin-echo for multiple mouse magnetic resonance phenotyping
Nieman BJ, Bock NA, Bishop J, Sled JG, Josette Chen X, Mark Henkelman Magn Reson Med. 2005 Sep;54(3):532-7 |
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Considerations for Setting up a Small-Animal Imaging Facility
Brenda A. Klaunberg, MS, VMD & Martin J. Lizak, PhD Lab Animal2004 Mar;33(3):28-34 |
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Ultrasound-guided left-ventricular catheterization: a novel method of whole mouse perfusion for microimaging
Zhou YQ, Davidson L, Henkelman RM, Nieman BJ, Foster FS, Yu LX, Chen XJ. Nature Biotechnology; Lab Invest. 2004 Mar;84(3):385-9. |
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A new ultrasound instrument for in vivo microimaging of mice
Foster FS, Zhang MY, Zhou YQ, Liu G, Mehi J, Cherin E, Harasiewicz KA, Starkoski BG, Zan L, Knapik DA, Adamson SL. Ultrasound in Medicine & Biology. 2002 Sep;28(9):1165-72. |
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Applications for multifrequency ultrasound biomicroscopy in mice from implantation to adulthood
Zhou YQ, Foster FS, Qu DW, Zhang M, Harasiewicz KA, Adamson SL. Physiol Genomics. 2002 Aug 14;10(2):113-26. |
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Advances in ultrasound biomicroscopy
F. Stuart Foster, Charles J. Pavlin, Kasia A. Harasiewicz, Donald A. Christopher And Daniel H. Turnbull Ultrasound Med Biol. 2000 Jan;26(1):1-27 |
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Techniques - Imaging Physics
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Tendon adhesion measured by a video-assisted gliding test in a chicken model
S.-C. Fu, L.-K. Hung, Y.-W. Lee, T.-Y. Mok, K.-M. Chan The Journal of Hand Surgery (European Volume). 2011 Jan;36(1):40-7. Epub 2010 Sep 3 |
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A new 15-50 MHz array-based micro-ultrasound scanner for preclinical imaging
F. Stuart Foster1, James Mehi2, Marc Lukacs1, Desmond Hirson2, Chris White2, Chris Chaggares2 and Andrew Needles2 Ultrasound in Medicine & Biology. 2009 Oct;35(10):1700-8. Epub 2009 Aug 3 |
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A method for differentiating targeted microbubbles in real time using subharmonic micro-ultrasound and interframe filtering
A. Needles, O. Couture and F.S. Foster Ultrasound in Medicine & Biology. 2009 Sep;35(9):1564-73. Epub 2009 Jul 25 |
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Increased shear rate resistance and fastest kinetics of erythrocyte aggregation in diabetes measured with ultrasound
Guy Cloutier, Audrey Zimmer, François T.H. Yu, and Jean-Louis Chiasson Diabetes Care. 2008 Jul;31(7):1400-2 |
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Left Ventricular Functional Assessment in Mice: Feasibility of High Spatial and Temporal Resolution ECG-gated Blood Pool SPECT
Bennett B. Chin, MD, Scott D. Metzler, PhD, Anthony Lemaire, MD, Antonio Curcio, MD, Sreekanth Vemulapalli, BS, Kim L. Greer, CNMT, Neil A. Petry, MS, Timothy G. Turkington, PhD, R. Edward Coleman, MD, Howard Rockman, MD, and Ronald J. Jaszczak, PhD Radiology. 2007 Nov;245(2):440-8 |
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Multispectral photoacoustic imaging of fluorochromes in small animals
Daniel Razansky, Claudio Vinegoni, and Vasilis Ntziachristos Optics Letters,2007 Oct 1;32(19):2891-3 |
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Model for the ultrasound reflection from micro-beads and cells distributed in layers on a uniform surface
O Couture , E Cherin and F S Foster Physics in Medicine and Biology. 2007 Jul 21;52(14):4189-204. Epub 2007 Jun 15 |
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Properties of an entropy-based signal receiver with an application to ultrasonic molecular imaging
M. S. Hughes, J. E. McCarthy , J. N. Marsh, J. M. Arbeit, R. G. Neumann, R. W. Fuhrhop, K. D. Wallace, and D. R. Znidersic, B. N. Maurizi , S. L. Baldwin, G. M. Lanza, and S. A. Wickline The Journal of the Acoustical Society of America,2007 Jun;121(6):3542-57 |
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Interframe Clutter Filtering For High Frequency Flow Imaging
Andrew Needles,* David E. Goertz,† Alison M. Cheung,* And F. Stuart Foster* Ultrasound in Med. & Biol., 2007 Apr; Vol. 33, No. 4, pp. 591–600, 2007. |
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Nonlinear ultrasound propagation through layered liquid and tissue-equivalent media: computational and experimental results at high frequency
Williams R, Cherin E, Lam TY, Tavakkoli J, Zemp RJ, Foster FS. Phys Med Biol. 2006 Nov 21;51(22):5809-24. Epub 2006 Oct |
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Characterization of Digital Waveforms Using Thermodynamic Analogs: Detection of Contrast-Targeted Tissue In Vivo
Michael S. Hughes, Member, IEEE, Jon N. Marsh, Member, IEEE, Hyuing Zhang, Adam K. Woodson, John S. Allen, Elizabeth K. Lacy, Cordelia Carradine, Gregory M. Lanza, and Samuel A. Wickline IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2006 Sep;53(9):1609-16 |
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Vascularized organoid engineered by modular assembly enables blood perfusion
Alison P. McGuigan and Michael V. Sefton PNAS. 2006 Aug 1;103(31):11461-6. Epub 2006 Jul 24 |
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Nanoparticles as image enhancing agents for ultrasonography
Liu J, Levine AL, Mattoon JS, Yamaguchi M, Lee RJ, Pan X, Rosol TJ. Phys Med Biol. 2006 May 7;51(9):2179-89. Epub 2006 Apr 10 |
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Investigating perfluorohexane particles with high-frequency ultrasound
Couture O, Bevan PD, Cherin E, Cheung K, Burns PN, Foster FS. Ultrasound Med Biol. 2006 Jan;32(1):73-82. |
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Comparison of Two Approaches to Volume Quantification for Free-Hand Ultrasound Scanning of Mouse Hearts
C. Garson, Y. Li, and J. Hossack IEEE Ultrasonics Symposium. 2005 Sept 18-21; Vol 1, PP. 491 - 494 |
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High-frequency ultrasound scattering from microspheres and single cells
R. E. Baddour1, M. D. Sherar1, J. W. Hunt1, G. J. Czarnota2, and M. C. Kolios3 The Journal of the Acoustical Society of America. 2005 Feb; 117(2): 934-943 |
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High Frequency Nonlinear B-Scan Imaging of Microbubble Contrast Agents
David E. Goertz, Emmanuel Cherin, Andrew Needles, Raffi Karshafian, Allison S. Brown, Peter N. Burns, and F. Stuart Foster IEEE Ultrasonics, Ferroelectrics, And Frequency Control Society. 2005 Jan; Vol. 52, Issue 1 |
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Biological effects of high-frequency ultrasound exposure during mouse organogenesis
Allison S. Brown*, Angela D. Reid*, Lisa Leamen*, Viviene Cucevic* and F. Stuart Foster*, † Ultrasound Med Biol. 2004 Sep;30(9):1223-32 |
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Thermal assessment of 40-MHz ultrasound at soft tissue-bone interfaces
AS Duckett , AD Reid, L Leamen , V Cucevic , FS Foster Ultrasound Med Biol. 2004 May;30(5):665-73. |
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Techniques - Image-Guided Injection
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Neuregulin-1 potentiates agrin-induced acetylcholine receptor clustering through muscle-specific kinase phosphorylation
Shyuan T. Ngo1, Rebecca N. Cole3, Nana Sunn2, William D. Phillips3, and Peter G. Noakes1,2 Journal of Cell Science. 2012 Feb 10. [Epub ahead of print] |
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Lipid phosphate phosphatase 3 enables efficient thymic egress
Béatrice Bréart1, Willy D. Ramos-Perez1, Alejandra Mendoza1, Abdelghaffar K. Salous2, Michael Gobert1, Yong Huang3, Ralf H. Adams4,5, Juan J. Lafaille1, Diana Escalante-Alcalde6, Andrew J. Morris2, and Susan R. Schwab1 The Journal of Experimental Medicine. 2011 Jun 6;208(6):1267-78. Epub 2011 May 16 |
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Peripheral Nervous System Progenitors Can Be Reprogrammed to Produce Myelinating Oligodendrocytes and Repair Brain Lesions
Ellen Binder1, Marion Rukavina2, Hessameh Hassani3, Marlen Weber1, Hiroko Nakatani3, Tobias Reiff1, Carlos Parras3, Verdon Taylor2,4, and Hermann Rohrer1 The Journal of Neuroscience. 2011 Apr 27;31(17):6379-6391 |
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SSTR2-based reporters for assessing gene transfer into non-small cell lung cancer: evaluation using an intrathoracic mouse model
S.P. Singh,1 L. Han,1 R. Murali,1 L. Solis,2 J. Roth,3 L. Ji,4 I. Wistuba,2 and V. Kundra1,5 Human Gene Therapy. 2011 Jan;22(1):55-64. Epub 2010 Dec 6 |
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Temporal Characterization of the Functional Density of the Vasa Vasorum by Contrast-Enhanced Ultrasonography Maximum Intensity Projection Imaging
Sang Chol Lee, MD1,2, Chad L. Carr, MD1, Brian P. Davidson, MD1, Dilantha Ellegala, MD1, Aris Xie, MS1, Azzdine Ammi, PhD1, Todd Belcik, BS, RDCS1, Jonathan R. Lindner, MD1 The American College of Cardiology Foundation JACC Cardiovascular Imaging. 2010 Dec;3(12):1265-72 |
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Notch3 in Human Breast Cancer Cell Lines Regulates Osteoblast-Cancer Cell Interactions and Osteolytic Bone Metastasis
Zhiyuan Zhang1,5, Hao Wang1, Sadakatsu Ikeda2, Frederic Fahey3, Diane Bielenberg4, Patrick Smits1 and Peter V. Hauschka1,5 The American Journal of Pathology. 2010 Sep;177(3):1459-69. Epub 2010 Jul 22 |
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Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos
Slobodan Beronja1,2, Geulah Livshits1,2, Scott Williams1 & Elaine Fuchs1 Nature Medicine. 2010 Jul;16(7):821-7. Epub 2010 Jun 6 |
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Origin and Molecular Specification of Globus Pallidus Neurons
Sandrina N�brega-Pereira1,2, Diego Gelman1, Giorgia Bartolini1, Ram�n Pla1, Alessandra Pierani3 and Oscar Mar�n1 The Journal of Neuroscience. 2010 Feb 24;30(8):2824-34 |
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Area-specific temporal control of corticospinal motor neuron differentiation by COUP-TFI
Giulio Srubek Tomassy1, Elvira De Leonibus1,2, Denis Jabaudon3,4, Simona Lodato1, Christian Alfano1, Andrea Mele2, Jeffrey D. Macklis3, and Mich�le Studer1,5 Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2010 Feb 23;107(8):3576-3581. Epub 2010 Feb 2 |
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Novel subtype-specific genes identify distinct subpopulations of callosal projection neurons
Bradley J. Molyneaux, Paola Arlotta, Ryann M. Fame, Jessica L. MacDonald, Kyle L. MacQuarrie and Jeffrey D. Macklis The Journal of Neuroscience. 2009 Sep 30;29(39):12343-54 |
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Reduced Vessel Elasticity Alters Cardiovascular Structure and Function in Newborn Mice
Jessica E. Wagenseil; Chris H. Ciliberto ; Russell H. Knutsen ; Marilyn A. Levy ; Attila Kovacs ; and Robert P. Mecham Circulation Research. 2009 May 22;104(10):1217-24. Epub 2009 Apr 16 |
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Induction of factor VIII-specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia A
S. Madoiwa1; T. Yamauchi; E. Kobayashi2; Y. Hakamata2; M. Dokai1; N. Makino1; Y. Kashiwakura1; A. Ishiwata1; T. Ohmori1; J. Mimuro1; Y. Sakata1 Journal of Thrombosis and Haemostasis. 2009 May;7(5):811-24. Epub 2009 Feb 12 |
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microRNA-1 negatively regulates expression of the hypertrophy-associated genes calmodulin and Mef2a
Sadakatsu Ikeda, Aibin He, Sek Won Kong, Jun Lu, Rafael Bejar, Natalya Bodyak, Kyu-Ho Lee, Qing Ma, Peter M. Kang, Todd R. Golub, and William T. Pu Molecular and Cell Biology 2009 Apr;29(8):2193-204. Epub 2009 Feb 2 |
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Neural progenitors of the postnatal and adult mouse forebrain retain the ability to self-replicate, form neurospheres and undergo multipotent differentiation in vivo
Bettina Neumeister, Antje Grabosch, Onur Basak, Rolf Kemler and Verdon Taylor Stem Cells (Dayton, Ohio). 2009 Mar;27(3):714-23: 2008 Dec 18. [Epub ahead of print] |
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High-resolution magnetic resonance histology of the embryonic and neonatal mouse: A 4D atlas and morphologic database
Alexandra E. Petiet, Matthew H. Kaufman, Matthew M. Goddeeris, Jeffrey Brandenburg, Susan A. Elmore, and G. Allan Johnson Proceedings of the National Academy of Sciences of the United States of America. 2008 Aug 26;105(34):12331-6 |
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Cystic Adenomatoid Malformations Are Induced by Localized FGF10 Overexpression in Fetal Rat Lung
Sílvia Gonzaga, Tiago Henriques-Coelho, Marcus Davey, Philip W. Zoltick, Adelino F. Leite-Moreira, Jorge Correia-Pinto and Alan W. Flake American Journal of Respiratory Cell and Molecular Biology. 2008 Apr 17, Vol. 39, pp. 346-355, 2008 |
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Ultrasound-guided in utero injections allow studies of the development and function of the eye
Claudio Punzo and Constance L. Cepko Developmental dynamics. 2008 Apr;237(4):1034-42 |
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Chemokine Signaling Controls Intracortical Migration and Final Distribution of GABAergic Interneurons
Guillermina Lopez-Bendito, Juan Antonio Sánchez-Alcañiz, Ramón Pla, Víctor Borrell, Esther Picó, Miguel Valdeolmillos, and Oscar Marín The Journal of Neuroscience. 2008 Feb 13;28(7):1613-24 |
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Delineation of Multiple Subpallial Progenitor Domains by the Combinatorial Expression of Transcriptional Codes
Nuria Flames,1 Ramón Pla,1 * Diego M. Gelman,1 * John L. R. Rubenstein,2 Luis Puelles,3,4 and Oscar Marín1 The Journal of Neuroscience. 2007 Sep 5;27(36):9682-95 |
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Design, calibration and evaluation of a robotic needle-positioning system for small animal imaging applications
Waspe AC, Cakiroglu HJ, Lacefield JC, Fenster A. Phys Med Biol. 2007 Apr 7;52(7):1863-78. Epub 2007 Mar 9. |
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Targeted gene transfer to fetal rat lung interstitium by ultrasound-guided intrapulmonary injection
Henriques-Coelho T, Gonzaga S, Endo M, Zoltick PW, Davey M, Leite-Moreira AF, Correia-Pinto J, Flake AW. Mol Ther. 2007 Feb;15(2):340-7. |
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Layer acquisition by cortical GABAergic interneurons is independent of Reelin signaling
Pla R, Borrell V, Flames N, Marin O. J Neurosci. 2006 Jun 28;26(26):6924-34. |
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Embryonic and Neonatal Phenotyping of Genetically Engineered Mice
Shathiyah Kulandavelu, Dawei Qu, Nana Sunn, Junwu Mu, Monique Y. Rennie, Kathie J. Whiteley, Johnathon R. Walls, Nicholas A. Bock, John C. H. Sun, Andrea Covelli, John G. Sled, and S. Lee Adamson ILAR Journal, 2006 Mar; 47(2):103-17 |
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High resolution ultrasound-guided microinjection for interventional studies of early embryonic and placental development in vivo in mice
John C. Slevin, Lois Byers, Marina Gertsenstein, Dawei Qu, Junwu Mu, Nana Sunn, John C.P. Kingdom, Janet Rossant and S. Lee Adamson BMC Developmental Biology,2006 Feb 27; 6:10 |
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Anatomical phenotyping in the brain and skull of a mutant mouse by magnetic resonance imaging and computed tomography
Brian J. Nieman1,2, Ann M. Flenniken3, S. Lee Adamson3,4, R. Mark Henkelman1,2 and John G. Sled1,2 Physiological Genomics. 2006 Jan 12;24(2):154-62 |
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Image-Guided Cardiac Cell Delivery Using High-Resolution Small-Animal Ultrasound
Rodriguez-Porcel M, Gheysens O, Chen IY, Wu JC, Sam Gambhir S. Molecular Therapy. 2005 Dec;12(6):1142-7. Epub 2005 Aug 18 |
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Fezl is required for the birth and specification of corticospinal motor neurons
Molyneaux BJ, Arlotta P, Hirata T, Hibi M, Macklis JD Neuron. 2005 Sep 15;47(6):817-31 |
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Fast spin-echo for multiple mouse magnetic resonance phenotyping
Nieman BJ, Bock NA, Bishop J, Sled JG, Josette Chen X, Mark Henkelman Magn Reson Med. 2005 Sep;54(3):532-7 |
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Closed-Chest Cell Injections into Mouse Myocardium Guided by High-Resolution Echocardiography
Springer ML, Sievers RE, Viswanathan MN, Yee MS, Foster E, Grossman W, Yeghiazarians Y. American Journal of Physiology - Heart Circ Physiol. 2005 Sep;289(3):H1307-14. Epub 2005 May 20 |
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Neuronal Subtype-Specific Genes that Control Corticospinal Motor Neuron Development In Vivo
Paola Arlotta1,3, Bradley J. Molyneaux1, 3, Jinhui Chen1, 4, Jun Inoue2, Ryo Kominami2 and Jeffrey D. Macklis, 1 Neuron. 2005 Jan 20; Vol 45, Issue 2, PP. 207-221 |
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Ultrasound-guided left-ventricular catheterization: a novel method of whole mouse perfusion for microimaging
Zhou YQ, Davidson L, Henkelman RM, Nieman BJ, Foster FS, Yu LX, Chen XJ. Nature Biotechnology; Lab Invest. 2004 Mar;84(3):385-9. |
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Ultrasound backscatter microscope analysis of early mouse embryonic brain development
Turnbull DH, Bloomfield TS, Baldwin HS, Foster FS, Joyner AL. Proc Natl Acad Sci U S A. 1995 Mar 14;92(6):2239-43. |
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Techniques - Visualization of Vascularity
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A method for differentiating targeted microbubbles in real time using subharmonic micro-ultrasound and interframe filtering
A. Needles, O. Couture and F.S. Foster Ultrasound in Medicine & Biology. 2009 Sep;35(9):1564-73. Epub 2009 Jul 25 |
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Tumor Vascular Changes Mediated by Inhibition of Oncogenic Signaling
Naseer Qayum 1, Ruth J. Muschel 1, Jae Hong Im 1, Lukxmi Balathasan 1, Cameron J. Koch 2, Sonal Patel 3, W. Gillies McKenna 1, and Eric J. Bernhard 1 Cancer Research. 2009 Aug 1;69(15):6347-54. Epub 2009 Jul 21 |
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Detectability of small blood vessels with high-frequency power Doppler and selection of wall filter cut-off velocity for microvascular imaging
Stephen Z. Pinter, James C. Lacefield Ultrasound in Medicine & Biology. 2009 Jul;35(7):1217-28. Epub 2009 Apr 25 |
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Intravascular Ultrasound (IVUS): A Potential Arthroscopic Tool for Quantitative Assessment of Articular Cartilage
Yan-Ping Huang1 and Yong-Ping Zheng1,2 The open biomedical engineering journal. 2009 Jun 26;3:13-20 |
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Cytosolic Phospholipase A2: Targeting Cancer through the Tumor Vasculature
Amanda Linkous, Ling Geng, Andrej Lyshchik, Dennis E. Hallahan, Eugenia M. Yazlovitskaya Clinical Cancer Research. 2009 Mar 1;15(5):1635-44. Epub 2009 Feb 24 |
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Ultrasound and Doppler micro-imaging in a model of rheumatoid arthritis in mice
Gaëlle Clavel 1, Carmen Marchiol-Founigault 2, Gilles Renault 2, Marie-Christophe Boissier 2, Didier Fradelizi 2 and Natacha Bessis 2* Annals of the Rheumatic Diseases. 2008 Dec; 67: 1765 - 1772 |
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Mitogen-activated protein kinase kinase signaling promotes growth and vascularization of fibrosarcoma
Yan Ding, Elissa A. Boguslawski, Bree D. Berghuis, John J. Young, Zhongfa Zhang, Kim Hardy, Kyle Furge, Eric Kort, Arthur E. Frankel, Rick V. Hay, James H. Resau and Nicholas S. Duesbery Molecular Cancer Therapeutics. 2008 March 1;7: 648-658. |
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In Vivo Measurement of Flow-Mediated Vasodilation in Living Rats using High-Resolution Ultrasound
Christian Heiss1, Richard E. Sievers2, Nicolas Amabile1, Tony Y Momma3, Qiumei Chen2, Shobha Natarajan1, Yerem Yeghiazarians1, and Matthew L. Springer1* Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H1086-93. Epub 2007 Nov 30 |
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Inhibition of N-Ethylmaleimide-Sensitive Factor Protects Against Myocardial Ischemia/Reperfusion Injury
John W. Calvert, Susheel Gundewar, Munekazu Yamakuchi, Pierce C. Park, William M. Baldwin III, David J. Lefer, Charles J. Lowenstein Circ Res. 2007 Dec 7;101(12):1247-54; Epub 2007 Oct 11 |
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Microultrasound Molecular Imaging of Vascular Endothelial Growth Factor Receptor 2 in a Mouse Model of Tumor Angiogenesis
Joshua J. Rychak, James Graba, Alison M.Y. Cheung, Bina S. Mystry, Jonathan R. Lindner, Robert S. Kerbel, and F. Stuart Foster Molecular Imaging. 2007 Sep-Oct; 6(5): PP. 289–296 |
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Detecting Vascular Changes In Tumour Xenografts Using Micro-Ultrasound And Micro-Ct Following Treatment With VEGFR-2 Blocking Antibodies
ALISON M. Y. CHEUNG,* ALLISON S. BROWN,* VIVIENE CUCEVIC,* MARCIA ROY,* ANDREW NEEDLES,* VICTOR YANG,* DANIEL J. HICKLIN,‡ ROBERT S. KERBEL,† and F. STUART FOSTER* Ultrasound in Med. & Biol. 2007 Aug;33(8):1259-68. Epub 2007 Apr 30 |
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Molecular Imaging of Inflammation in Atherosclerosis With Targeted Ultrasound Detection of Vascular Cell Adhesion Molecule-1
Beat A. Kaufmann, MD; John M. Sanders, BS; Christopher Davis, MD; Aris Xie, MS; Patrick Aldred, MS; Ian J. Sarembock, MB, ChB; Jonathan R. Lindner, MD Circulation. 2007 Jul 17;116(3):276-84. Epub 2007 Jun 25 |
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Therapy-Induced Acute Recruitment of Circulating Endothelial Progenitor Cells to Tumors
Shaked Y, Ciarrocchi A, Franco M, Lee CR, Man S, Cheung AM, Hicklin DJ, Chaplin D, Foster FS, Benezra R, Kerbel RS. Science. 2006 Sep 22;313(5794):1785-7 |
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Ultrahigh frame rate retrospective ultrasound microimaging and blood flow visualization in mice in vivo.
Emmanuel Chérin, Ross Williams, Andrew Needles, Godwin Liu, Christopher White, Allison S. Brown, Yu-Qing Zhou and F. Stuart Foster Ultrasound in Medicine & Biology. 2006 May; Vol 32, Issue 5, PP. 683-691 |
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Targeted anti-vascular endothelial growth factor receptor-2 therapy leads to short-term and long-term impairment of vascular function and increase in tumor hypoxia
Franco M, Man S, Chen L, Emmenegger U, Shaked Y, Cheung AM, Brown AS, Hicklin DJ, Foster FS, Kerbel RS. Cancer Research. 2006 Apr 1;66(7):3639-48. |
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Fibroblast-derived MT1-MMP promotes tumor progression in vitro and in vivo
Wenyue Zhang, Lynn M Matrisian, Kenn Holmeck, Catherine C Vick and Eben L Rosenthal BMC Cancer2006 March 6; 6:52 |
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Ultrasonic Molecular Imaging of Primordial Angiogenic Vessels in Rabbit and Mouse Models With v3-integrin Targeted Nanoparticles Using Information-Theoretic Signal Detection: Results at High Frequency and in the Clinical Diagnostic Frequency Range
M. Hughes, J. N. Marsh, Jeffrey Arbeit, Robert Neumann,R. W. Fuhrhop, G. M. Lanza, and S. A. Wickline IEEE Ultrasonics Symposium. 2005 Sept 18-21; Vol: 1, PP. 617- 620 |
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High-frequency, nonlinear flow imaging of microbubble contrast agents
Goertz DE, Needles A, Burns PN, Foster FS. IEEE Trans Ultrason Ferroelectr Freq Control. 2005 Mar;52(3):495-502. |
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High-frequency Doppler ultrasound monitors the effects of antivascular therapy on tumor blood flow.
Goertz DE, Yu JL, Kerbel RS, Burns PN, Foster FS. Cancer Research. 2002 Nov 15;62(22):6371-5. |
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