Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca²⁺ release channel
Naohiro Yamaguchi¹, Nobuyuki Takahashi², Le Xu¹, Oliver Smithies² and Gerhard Meissner^1
11Department of Biochemistry and Biophysics and ²Department of Pathology and Laboratory Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
J. Clin. Invest. 117:1344-1353 (2007)

Micro-ultrasound imaging assessment of carotid plaque characteristics in apolipoprotein-E knockout mice.
Ni M, Zhang M, Ding SF, Chen WQ, Zhang Y.
The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong, PR China.
Atherosclerosis. 2007 Sep 15; [Epub ahead of print]

Progressive Troponin I Loss Impairs Cardiac Relaxation and Causes Heart Failure in Mice.
Liu J, Du J, Zhang C, Walker JW, Huang X.
Biomedical Science, Florida Atlantic University, Boca Raton, Florida.
Am J Physiol Heart Circ Physiol. 2007 May 25.

Reconsidering the Layer Thickness Distribution in Aortic Valve Cusps Using High-Frequency Ultrasound
Zamir Khan^1,2, Derek R. Boughner^1,2,3, and James C. Lacefield^1,2
1University of Western Ontario, London, ON, Canada
²Robarts Research Institute, London, ON, Canada
³London Health Sciences Centre, London, ON, Canada
IEEE, June 2007

Measurements of Aneurysm Morphology Determined by 3-D Micro-Ultrasound Imaging as Potential Quantitative Biomarkers in a Mouse Aneurysm Model
Goldberg A, Pakkiri P, Dai E, Lucas A, Fenster A.
Robarts Research Institute, London, Ontario, Canada; Department of Biophysics, University of Western Ontario, London, Ontario, Canada.
Ultrasound Med Biol. 2007 Jun 27; [Epub ahead of print]

Cardiac Specific Haploin sufficiency of ß-Catenin Attenuates Cardiac Hypertrophy But Enhances Fetal Gene Expression in Response to Aortic Constriction
Jiaxiang Qu¹, Jibin Zhou¹, Xian Ping Yi^1,2, Baojun Dong¹, Hanqiao Zheng¹, Lisa M. Miller¹, Xuejun Wang¹, Michael D. Schneider⁴, Faqian Li^1
1Sanford Research/USD, Cardiovascular Research Institute, The University of South Dakota and Sanford Health, Sioux Falls, SD, ²Department of Pathology, Zhongshan University the Fifth Affiliated Hospital, P. R. China., ⁴Department of Medicine, Department of Cell Biology, and Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas.

Cardiac repolarization is prolonged in CD4C/HIV transgenic mice
Judith Brouillette^a,b, Scott A. Grandy^a,b, Paul Jolicoeur^c, Céline Fiset^a,b
aResearch Center, Montreal Heart Institute, 5000 Belanger Street, Montreal, Quebec, Canada H1T 1C8
^bFaculty of Pharmacy, University of Montreal, Canada
^cClinical Research Institute of Montreal, Canada
J Mol Cell Cardiol. 2007 May 18; [Epub ahead of print]

Cardiovascular Developmental Insights from Embryos
BRADLEY B. KELLER, LI J. LIU, JOSEPH P. TINNEY AND KIMIMASA TOBITA
Division of Pediatric Cardiology, Department of Pediatrics, Children’s Hospital of Pittsburgh Heart Center, Pittsburgh, Pennsylvania, USA
Ann N Y Acad Sci. 2007 Apr;1101:377-88. Epub 2007 Feb 15.

Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity.
Trivedi CM, Luo Y, Yin Z, Zhang M, Zhu W, Wang T, Floss T, Goettlicher M, Noppinger PR, Wurst W, Ferrari VA, Abrams CS, Gruber PJ, Epstein JA.
Department of Cell and Developmental Biology, 1156 Basic Research Building II, University of Pennsylvania School of Medicine, 421 Curie Boulevard, Philadelphia, Pennsylvania 19104, USA.
Nat Med. 2007 Mar;13(3):324-31. Epub 2007 Feb 18.

Proteasome inhibition attenuates infarct size and preserves cardiac function in a murine model of myocardial ischemia-reperfusion injury.
Stansfield WE, Moss NC, Willis MS, Tang R, Selzman CH.
Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Ann Thorac Surg. 2007 Jul;84(1):120-5.

Comparative Study of High-resolution Microimaging with 30-MHz Scanner for Evaluating Cardiac Function in Mice.
Okajima K, Abe Y, Fujimoto K, Fujikura K, Girard EE, Asai T, Kwon SH, Jin Z, Nakamura Y, Yoshiyama M, Homma S.
Department of Medicine, Division of Cardiology, Columbia University, New York, New York.
J Am Soc Echocardiogr. 2007 Jun 22; [Epub ahead of print]

Deleterious effects of lack of cardiac PAI-1 after coronary occlusion in mice and their pathophysiologic determinants.
Zaman AK, Fujii S, Schneider DJ, Taatjes DJ, Lijnen HR, Sobel BE.
Cardiovascular Research Institute, University of Vermont, Colchester Research Facility, Colchester, VT
Histochem Cell Biol. 2007 Jun 19; [Epub ahead of print]

Ultrasound biomicroscopy permits in vivo characterization of zebrafish liver tumors.
Goessling W, North TE, Zon LI.
Stem Cell Program, Hematology/Oncology, Children's Hospital and Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, Massachusetts
Nat Methods. 2007 Jun 17; [Epub ahead of print]

Therapeutic effect of CS-706, a specific cyclooxygenase-2 inhibitor, on gallbladder carcinoma in BK5.ErbB-2 mice.
Kiguchi K, Ruffino L, Kawamoto T, Franco E, Kurakata S, Fujiwara K, Hanai M, Rumi M, Digiovanni J.
Department of Carcinogenesis, The University of Texas M. D. Anderson Cancer Center, Science Park-Research Division, Smithville, TX
Mol Cancer Ther. 2007 Jun;6(6):1709-17.

Pulse doppler and M-mode to assess viability of cardiac allografts using heterotopic femoral heart transplantation in rats.
Gordon CR, Lefebvre DR, Matthews MS, Strande LF, Marra SW, Guglielmi M, Skaf J, Hollenberg SM, Hewitt CW.
Division of Surgical Research, Department of Surgery, Robert Wood Johnson Medical School, Cooper
Microsurgery. 2007;27(4):240-4.

Myocardial Elastography At Both High Temporal And Spatial Resolution For The Detection Of Infarcts
JIANWEN LUO,^* KANA FUJIKURA,^* SHUNICHI HOMMA,^† and ELISA E. KONOFAGOU^*‡
*Department of Biomedical Engineering; ^†Department of Medicine; and ‡Department of Radiology, Columbia University, New York, NY, USA
Ultrasound in Med. 2007 Jun 12; [Epub ahead of print]

NON-INVASIVE ULTRASONIC MEASUREMENT OF REGIONAL AND LOCAL PULSE-WAVE VELOCITY IN MICE.
Williams R, Needles A, Cherin E, Zhou YQ, Henkelman RM, Adamson SL, Foster FS.
Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
Ultrasound Med Biol. 2007 Jun 8; [Epub ahead of print]

Fgl2 deficiency causes neonatal death and cardiac dysfunction during embryonic and postnatal development in mice.
Mu J, Qu D, Bartczak A, Phillips MJ, Manuel J, He W, Koscik C, Mendicino M, Zhang L, Clark DA, Grant DR, Backx PH, Levy GA, Adamson SL.
Samuel Lunenfeld Research Institute of Mount Sinai Hospital, Toronto, Canada.
Physiol Genomics. 2007 Jun 5; [Epub ahead of print]

An ultrasound imaging method for in vivo tracheal bulk and Young's moduli of elasticity.
Miller TL, Altman AR, Tsuda T, Shaffer TH.
Department of Pediatrics, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.
J Biomech. 2007;40(7):1615-21. Epub 2006 Oct 11.

Dysregulation of Cardiogenesis, Cardiac Conduction, and Cell Cycle in Mice Lacking miRNA-1-2
Yong Zhao^{1, 2, 3, 8}, Joshua F. Ransom^{1, 2, 3, 8}, Ankang Li^{6, 7}, Vasanth Vedantham^{1, 4}, Morgan von Drehle¹, Alecia N. Muth¹, Takatoshi Tsuchihashi^{1, 2, 3} Michael T. McManus⁵, Robert J. Schwartz⁶ and Deepak Srivastava^{1, 2, 3
1}Gladstone Institute of Cardiovascular Disease, 1650 Owens Street, San Francisco, CA 94158, USA
²Department of Pediatrics (Cardiology), University of California, San Francisco, San Francisco, CA 94143, US
. ³Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94143, USA
⁴Department of Internal Medicine (Cardiology), University of California, San Francisco, San Francisco, CA 94143, USA
⁵Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA
⁶Institute of Biosciences and Technology, Texas A & M Health Science Center, Baylor College of Medicine, Houston, TX 77030, USA
⁷Graduate Program in Cardiovascular Sciences, Baylor College of Medicine, Houston, TX 77030, USA
Cell, Volume 129, Issue 2, 20 April 2007, Pages 303-317

Overexpression of Bone Morphogenetic Protein 10 in Myocardium Disrupts Cardiac Postnatal Hypertrophic Growth
Hanying Chen^‡1, Weidong Yong^‡1, Shuxun Ren^§, Weihua Shen^‡, Yongzheng He^‡, Karen A. Cox^¶, Wuqiang Zhu^‡, Wei Li^‡, Mark Soonpaa^‡, R. Mark Payne^‡, Diego Franco^||, Loren J. Field^‡, Vicki Rosen^¶, Yibin Wang^§, and Weinian Shou^‡2
‡Herman B. Wells Center for Pediatric Research, Department of Pediatrics, Division of Pediatric Cardiology, Indiana University School of Medicine, Indianapolis, Indiana 46202, the ^§Departments of Anesthesiology, Physiology, and Medicine, Molecular Biology Institute, University of California, Los Angeles, California 90095, the ^¶Department of Developmental Biology, Harvard School of Dental Medicine, Boston, Massachusetts 02115, and the ^||Department of Experimental Biology, University of Jaen, 23071 Jaen, Spain
J. Biol. Chem., Vol. 281, Issue 37, 27481-27491, September 15, 2006

Enhancing Repair of the Mammalian Heart
Maria Paola Santini, Lana Tsao, Laurent Monassier, Catherine Theodoropoulos, Janice Carter, Enrique Lara-Pezzi, Esfir Slonimsky, Ekaterina Salimova, Patrice Delafontaine, Yao-Hua Song, Martin Bergmann, Christian Freund, Ken Suzuki, and Nadia Rosenthal
European Molecular Biology Laboratory (M.P.S., J.C., E.L.-P., E. Slonimsky, E. Salimova, N.R.), Mouse Biology Unit Monterotondo (Rome), Italy; Beth Israel Deaconess Medical Center, Cardiovascular Division (L.T.), Boston, Mass; Mouse Clinical Institute (L.M.), Illkirch Cedex, France; VisualSonics Inc (C.T.), Toronto, Ontario, Canada; Tulane University Health Sciences Center, Section of Cardiology (P.D., Y.-H.S.), New Orleans, La; Franz Volhart Clinic at MDC (M.B., C.F.), Charite’ Campus Buch, University Medicine Berlin, Germany; Harefield Heart Science Centre (K.S.), Imperial College London, UK; and the University of Cambridge (J.C.), Addenbrookes Hospital, Cambridge, UK.
Circ. Res. published online May 24, 2007;

Pulsed-high intensity focused ultrasound enhanced tPA mediated thrombolysis in a novel in vivo clot model: A pilot study
Michael J. Stone ^a,d, Victor Frenkel ^a, Sergio Dromi ^a, Peter Thomas ^b, Ryan P. Lewis ^a, King C.P. Li ^a, McDonald Horne III ^c, Bradford J. Wood ^a
aDiagnostic Radiology Department, Clinical Center, National Institutes of Health,
^bDivision of Bioengineering and Physical Science, Office of Research Services, National Institutes of Health, Bethesda,
^cDepartment of Laboratory Medicine, Clinical Center, National Institutes of Health, Howard Hughes Medical Institute Research Scholars Program, USA
Thrombosis Research, 2007, March 2007

Transitions in Early Embryonic Atrioventricular Valvular Function Correspond With Changes in Cushion Biomechanics That Are Predictable by Tissue Composition
Jonathan T. Butcher, Tim C. McQuinn, David Sedmera, Debi Turner, Roger R. Markwald
Circ. Res., published online May 3, 2007

ECG-Gated, Mechanical And Electromechanical Wave Imaging Of Cardiovascular Tissues In Vivo
MATHIEU PERNOT,^* KANA FUJIKURA,^* SIMON D. FUNG-KEE-FUNG,^* and ELISA E. KONOFAGOU^*†
*Department of Biomedical Engineering
^†Department of Radiology, Columbia University, New York
Ultrasound in Med. & Biol., Vol. 33, No. 7, pp. xxx, 2007

Kruppel-like factor 15 is a regulator of cardiomyocyte hypertrophy
Sudeshna Fisch^*, Susan Gray^*, Stephane Heymans^†, Saptarsi M. Haldar^‡, Baiqiu Wang^‡, Otmar Pfister, Lei Cui, Ajay Kumar^*, Zhiyong Lin^‡, Sucharita Sen-Banerjee^*, Hiranmoy Das^‡, Christine A. Petersen, Ulrike Mende^*, Barbara A. Burleigh, Yan Zhu_, Yigal Pinto^†, Ronglih Liao, and Mukesh K. Jain^‡*
‡Case Cardiovascular Research Institute, Case Western Reserve University School of Medicine
^*Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115
^†Experimental and Molecular Cardiology/CARIM, University of Maastricht, Maastricht, The Netherlands; and _Division of Cardiovascular Research, Caritas St. Elizabeth’s Medical Center, Tufts University School of Medicine, Boston
PNAS, April 24, 2007, vol. 104, No. 17

Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy
Michael H. Radke^*, Jun Peng^†, Yiming Wu^†, Mark McNabb^†, O. Lynne Nelson^‡, Henk Granzier^†, and Michael Gotthardt^*†
*Department of Neuromuscular and Cardiovascular Cell Biology, Max-Delbru¨ ck-Center for Molecular Medicine, Berlin-Buch, Germany
^†Department of Veterinary and Comparative Anatomy, Pharmacology, and Physiology
^‡Department of Veterinary Clinical Sciences, Washington State University, Pullman, WA
PNAS, February 27, 2007, V. 104, no. 9

Myocardial Infarct Size Measurement in the Mouse Chronic Infarction Model: Comparison of Area- and Length-Based Approaches
Junya Takagawa¹, Yan Zhang¹, Maelene L. Wong¹, Richard E. Sievers¹, Neel K. Kapasi¹, Yan Wang², Yerem Yeghiazarians¹, Randall J. Lee¹, William Grossman¹, and Matthew L. Springer^1
1University of California, San Francisco, Department of Medicine, Division of Cardiology, San Francisco, California, U.S.A
²FivePrime Therapeutics, Inc., San Francisco, California, U.S.A
J Appl Physiol., March 8, 2007

Detecting Vascular Changes In Tumour Xenografts Using Micro-Ultrasound And Micro-Ct Following Treatment With VEGFR2 Blocking Antibodies
ALISON M. Y. CHEUNG,^* ALLISON S. BROWN,^* VIVIENE CUCEVIC,^* MARCIA ROY,^* ANDREW NEEDLES,^* VICTOR YANG,^* DANIEL J. HICKLIN,^‡ ROBERT S. KERBEL,^† and F. STUART FOSTER^*
*Imaging Research and †Molecular and Cell Biology, Sunnybrook and Women’s College Health Sciences Centre, Toronto, ON, Canada; and ^‡ImClone Systems, New York, NY, USA
Ultrasound in Med. & Biol., Vol. 33, No. x, pp. xxx, 2007

Toll-like receptor stimulation in cardiomyoctes decreases contractility and initiates an NF-kappaB dependent inflammatory response
John H. Boyd, Sumeet Mathur, Yingjin Wang, Ryon M. Bateman, Keith R. Walley
Critical Care Research Laboratories, St. Paul's Hospital, University of British Columbia, 1081 Burrard Street, Vancouver, BC, Canada, V6Z 1Y6
Cardiovascular Research, 72 (2006) 384–393

Progressive Troponin I Loss Impairs Cardiac Relaxation and Causes Heart Failure in Mice
Jing Liu, Jianfeng Du, Chi Zhang, Jeffery W. Walker, Xupei Huang
Department of Biomedical Science and Center for Molecular Biology and Biotechnology, Florida Atlantic University, Boca Raton, FL
Am J Physiol Heart Circ Physiol., May 25, 2007.

Characterization of circulatory disorders in ß-thalassemic mice by noninvasive ultrasound biomicroscopy
Ekatherina Stoyanova¹, Marie Trudel², Hady Felfly², Damien Garcia² and Guy Cloutier^1
1 University of Montreal Hospital Research Center, Montreal, Quebec, Canada
² Clinical Research Institute of Montreal, Montreal, Quebec, Canada
Physiol. Genomics 29: 84-90, 2007.

S100A1 gene therapy preserves in vivo cardiac function after myocardial infarction.
Pleger ST, Remppis A, Heidt B, Volkers M, Chuprun JK, Kuhn M, Zhou RH, Gao E, Szabo G, Weichenhan D, Muller OJ, Eckhart AD, Katus HA, Koch WJ, Most P.
Medizinische Universitatsklinik und Poliklinik III, Otto Meyerhof Zentrum, Universitat zu Heidelberg, Germany.
Mol Ther. 2005 Dec;12(6):1120-9. Epub 2005 Sep 15.

Design, calibration and evaluation of a robotic needle-positioning system for small animal imaging applications.
Waspe AC, Cakiroglu HJ, Lacefield JC, Fenster A.
Biomedical Engineering Graduate Program, University of Western Ontario, London, Ontario
Phys Med Biol. 2007 Apr 7;52(7):1863-78. Epub 2007 Mar 9.

Increased Ventricular Preload Is Compensated by Myocyte Proliferation in Normal and Hypoplastic Fetal Chick Left Ventricle.
Dealmeida A, McQuinn T, Sedmera D.
Department of Cell Biology and Anatomy, Pediatric Cardiology , Medical University of South Carolina, Charleston; Institute of Anatomy, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Circ Res. 2007 Apr 5; [Epub ahead of print]

Targeted gene transfer to fetal rat lung interstitium by ultrasound-guided intrapulmonary injection.
Henriques-Coelho T, Gonzaga S, Endo M, Zoltick PW, Davey M, Leite-Moreira AF, Correia-Pinto J, Flake AW.
The Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Mol Ther. 2007 Feb;15(2):340-7.

Quantification and mri validation of regional contractile dysfunction in mice post myocardial infarction using high resolution ultrasound.
Li Y, Garson CD, Xu Y, Beyers RJ, Epstein FH, French BA, Hossack JA.
Ultrasound Med Biol. 2007 Apr 13; [Epub ahead of print]

Morphological and functional evaluation of murine heterotopic cardiac grafts using ultrasound biomicroscopy.
Zhou YQ, Bishay R, Feintuch A, Tao K, Golding F, Zhu W, West LJ, Henkelman RM.
Ultrasound Med Biol. 2007 Apr 13; [Epub ahead of print]

Interframe Clutter Filtering For High Frequency Flow Imaging.
Andrew Needles,^* David E. Goertz,^† Alison M. Cheung,^* And F. Stuart Foster^*
*Sunnybrook Health Sciences Centre, Toronto, Canada; and ^†Erasmus Medical Center, Rotterdam, The Netherlands
Ultrasound in Med. & Biol., Vol. 33, No. 4, pp. 591–600, 2007.

A Peptide Conjugate of Vitamin E Succinate Targets Breast Cancer Cells with High ErbB2 Expression.
Wang XF, Birringer M, Dong LF, Veprek P, Low P, Swettenham E, Stantic M, Yuan LH, Zobalova R, Wu K, Ledvina M, Ralph SJ, Neuzil J.
Apoptosis Research Group and Genomics Research Centre, School of Medical Science, Griffith University, Southport, Queensland, Australia.
Cancer Res. 2007 Apr 1;67(7):3337-44.

Upregulation of gamma-catenin compensates for the loss of beta-catenin in adult cardiomyocytes.
Zhou J, Qu J, Yi XP, Graber K, Huber L, Wang X, Gerdes AM, Li F.
Cardiovascular Research Institute, South Dakota Health Research Foundation, Sioux Falls, SD
Am J Physiol Heart Circ Physiol. 2007 Jan;292(1):H270-6. Epub 2006 Aug 25.

Initial Experience with High Frequency Ultrasound for the Newborn C57BL Mouse.
Alok K. Bose, M.D.^*, James W. Mathewson, M.D.^*, Brent E. Anderson, B.S.^†, Allyson M. Andrews, B.A.^*, A. Martin Gerdes, Ph.D.^†, M. Benjamin Perryman, Ph.D.^† and Paul D. Grossfeld, M.D.^*
*Division of Cardiology, University of California at San Diego and Children's Hospital of San Diego, San Diego, California, ^†The Cardiovascular Research Institute–South Dakota Health Research Foundation, University of South Dakota and Sioux Valley Hospital, South Dakota
Echocardiography, Volume 24 Issue 4 Page 412 - April 2007

Myostatin does not regulate cardiac hypertrophy or fibrosis.
Cohn RD, Liang HY, Shetty R, Abraham T, Wagner KR.
McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, USA.
Neuromuscul Disord. 2007 Mar 1; [Epub ahead of print]

The host immune response is essential for the beneficial effect of adult stem cells after myocardial ischemia.
Tolar J, Wang X, Braunlin E, McElmurry RT, Nakamura Y, Bell S, Xia L, Zhang J, Hu Q, Panoskaltsis-Mortari A, Zhang J, Blazar BR.
Cancer Center and Department of Pediatrics, Division of Hematology-Oncology, Blood and Marrow Transplantation, University of Minnesota, Minneapolis, Minn., USA.
Exp Hematol. 2007 Apr;35(4):682-90.

Evaluation of an algorithm for semiautomated segmentation of thin tissue layers in high-frequency ultrasound images.
Qiu Q, Dunmore-Buyze J, Boughner DR, Lacefield JC.
University of Western Ontario, London, Ontario
IEEE Trans Ultrason Ferroelectr Freq Control. 2006 Feb;53(2):324-34

Functional Neoangiogenesis Imaging of Genetically Engineered Mouse Prostate Cancer Using Three-Dimensional Power Doppler Ultrasound.
Jim W. Xuan,¹, Michael Bygrave⁶, Hongyi Jiang¹, Fatma Valiyeva¹, Joy Dunmore-Buyze⁶, David W. Holdsworth^2,6, Jonathan I. Izawa¹, Glenn Bauman³, Madeleine Moussa⁴, Scott F. Winter⁷, Norman M. Greenberg⁷, Joseph L. Chin¹, Maria Drangova^2,6, Aaron Fenster^2,3,6 and James C. Lacefield^2,5,6
Departments of ¹ Surgery, ² Medical Biophysics, ³ Oncology, ⁴ Pathology, and ⁵ Electrical and Computer Engineering, University of Western Ontario and ⁶ Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada; and ⁷ Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington
Cancer Research 67, 2830-2839, March 15, 2007

A point mutation (R192H) in the C-terminus of human cardiac troponin I causes diastolic dysfunction in transgenic mice.
Du J, Zhang C, Liu J, Sidky C, Huang XP.
Department of Biomedical Science and Center for Molecular Biology and Biotechnology, Florida Atlantic University.
Arch Biochem Biophys. 2006 Dec 15;456(2):143-50. Epub 2006 Sep 5

Nonlinear ultrasound propagation through layered liquid and tissue-equivalent media: computational and experimental results at high frequency.
Williams R, Cherin E, Lam TY, Tavakkoli J, Zemp RJ, Foster FS.
Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto.
Phys Med Biol. 2006 Nov 21;51(22):5809-24. Epub 2006 Oct

Ultrasonic characterization of whole cells and isolated nuclei.
Taggart LR, Baddour RE, Giles A, Czarnota GJ, Kolios MC.
Ontario Cancer Institute/Princess Margaret Hospital, University Health Network, Toronto, ON, Canada.
Ultrasound Med Biol. 2007 Mar;33(3):389-401

Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens.
Smith RR, Barile L, Cho HC, Leppo MK, Hare JM, Messina E, Giacomello A, Abraham MR, Marban E.
Division of Cardiology, Johns Hopkins University, Baltimore, MD, USA.
Circulation. 2007 Feb 20;115(7):896-908. Epub 2007 Feb 5

Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3beta activity.
Trivedi CM, Luo Y, Yin Z, Zhang M, Zhu W, Wang T, Floss T, Goettlicher M, Noppinger PR, Wurst W, Ferrari VA, Abrams CS, Gruber PJ, Epstein JA.
University of Pennsylvania School of Medicine, Pennsylvania, USA.
Nat Med. 2007 Mar;13(3):324-331. Epub 2007 Feb 18

S100A1 Gene Therapy Preserves in Vivo Cardiac Function after Myocardial Infarction.
Sven T. Pleger^1,2, Andrew Remppis¹, Beatrix Heidt¹, Mirko Völkers¹, J. Kurt Chuprun², Matthew Kuhn², Rui-Hai Zhou², Erhe Gao², Gabor Szabo³, Dieter Weichenhan¹, Oliver J. Müller¹, Andrea D. Eckhart², Hugo A. Katus¹, Walter J. Koch² and Patrick Most^1,2
1Medizinische Universitätsklinik und Poliklinik III, Otto Meyerhof Zentrum, Universität zu Heidelberg, INF 350, 69115 Heidelberg, Germany
²Center for Translational Medicine, Jefferson Medical College, 1025 Walnut Street, Philadelphia, PA 19107, USA
³Chirurgische Klinik der Universität Heidelberg, Abteilung für Herzchirurgie, INF 110, 69120 Heidelberg, Germany
MOLECULAR THERAPY. Vol. 12, No. 6, December 2005.

Sequential Alterations of Tracheal Mechanical Properties in the Neonatal Lamb: Effect of Mechanical Ventilation
Thomas L. Miller, PhD, Yan Zhu, MD, Allison R. Altman, BS,Kevin Dysart, MD and Thomas H. Shaffer, PhD
Pediatric Pulmonology. 42:141–149 (2007)

3D Visualisation and Quantification by Microcomputed Tomography of Late Gestational Changes in the Arterial and Venous Feto-Placental Vasculature of the Mouse.
M.Y. Rennie a, K.J. Whiteley b, S. Kulandavelu b,c, S.L. Adamson b,c, J.G. Sled
University of Toronto, Toronto, ON, Canada
Placenta. 2007 Feb 23; [Epub ahead of print]

Heat Shock Protein 90 and ErbB2 in the Cardiac Response to Doxorubicin Injury.
Kathleen Gabrielson, Djahida Bedja, Scott Pin, Allison Tsao, Lucio Gama, Bibo Yuan, and Nicole Muratore
Johns Hopkins University School of Medicine, Baltimore, Maryland
Cancer Res. 2007; 67: (4). February 15, 2007, 1436–41

Muscle Ring Finger 1, but not Muscle Ring Finger 2, Regulates Cardiac Hypertrophy In Vivo.
Monte S. Willis, Christopher Ike, Luge Li, Da-Zhi Wang, David J. Glass, Cam Patterson.
University of North Carolina, Chapel Hill, NC.
Circulation Research, 2007, In Press

Excitation of polymer-shelled contrast agents with high-frequency ultrasound.
Ketterling, J. A.; Mamou, J.; Allen, J. S.; Aristizabal, O.; Williamson, R. G.; Turnbull, D. H.
Journal of the Acoustical Society of America. Jan. 2007, PP. EL48-53

High-Resolution Myocardial Perfusion in Mice with High-Frequency Echocardiographic Detection of a Depot Contrast Agent.
Beat A. Kaufmann, MDab, Miles Lankford, BSb, Carolyn Z. Behm, MDb, Brent A. French, PhDb, Alexander L. Klibanov, PhDb, Yaqin Xu, MD, PhDb, Jonathan R. Lindner.
J of Am Society of Echo. Volume 20, Issue 2, PP. 136-143 (February 2007)

Secoisolariciresinol Diglucoside: Relevance to Angiogenesis and Cardioprotection against Ischemia-Reperfusion Injury.
Penumathsa SV, Koneru S, Thirunavukkarasu M, Zhan L, Prasad K, Maulik N.
Molecular Cardiology and Angiogenesis Laboratory, Department of Surgery, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT
J Pharmacol Exp Ther. 2006 Nov 28; [Epub ahead of print]

Doppler ultrasound in mice.
Stypmann J.
Department of Cardiology and Angiology, Hospital of the University of Munster, Germany.
Echocardiography.2007 Jan;24(1):97-112.

Detection of murine infarcts using myocardial elastography at both high temporal and spatial resolution.
Jianwen Luo Kana Fujikura Konofagou, E.E., Columbia University, New York
Conference Proceedings, Annual International Conference of the IEEE Engineering in Medicine and Biology Society,2006

Increasing Peripheral Artery Intima Thickness From Childhood to Seniority
Osika W, Dangardt F, Gronros J, Lundstam U, Myredal A, Johansson M, Volkmann R, Gustavsson T, Gan LM, Friberg P
Department of Metabolism and Cardiovascular Research/Clinical Physiology, Sahlgrenska University Hospital, Goteborg, Sweden; Department of Cardiology, Orebro University Hospital, Department of Physiology and Pharmacology, Goteborg University, Sweden; Department of Surgery, Sahlgrenska University Hospital/Ostra, Goteborg, Sweden; Department of Internal Medicine, Varberg Hospital, Sweden; Department of Signals and Systems, Chalmers University of Technology, Goteborg, Sweden.
Arterioscler Thromb Vasc Biol 2006 Dec 28; [Epub ahead of print]

Imaging kidney in conscious rats with high-frequency ultrasound and detection of two cases of unilateral congenital hydronephrosis.
Wang YX, Betton G, Floettmann E, Fantham E, Ridgwell G.
AstraZeneca Pharmaceuticals, Alderley Park, Macclesfield, Cheshire, UK.
Ultrasound Med Biol. 2006 Dec 21; [Epub ahead of print]

Techniques et applications de l’échographie haute résolution non invasive (Techniques and applications of non-invasive high-resolution ultrasound imaging).
J-M Grégoire, S Serrière, G Georgesco, F Jamet, A Bleuzen, F Ossant, F Levassort, F Tranquart, F PatatJ-M Grégoire, S Serrière, G Georgesco, F Jamet, A Bleuzen, F Ossant, F Levassort, F Tranquart, F Patat.
Laboratoire UltraSons Signaux et Instrumentation (LUSSI) ; INSERM.
Éditions Françaises de Radiologie, Vol 87 - N° 12-C2 - Décembre 2006

L’échographie haute résolution de la souris (High-resolution ultrasound imaging of the mouse)
G Renault, P Bonnin, C Marchiol-Fournigault, JM Gregoire, S Serrière, B Richard, D Fradelizi
Institut Cochin, Paris, France.
Éditions Françaises de Radiologie, Vol 87 - N° 12-C2 - Décembre 2006

Characterization of circulatory disorders in {beta}-thalassemic mice by non-invasive ultrasound biomicroscopy.
Stoyanova E, Trudel M, Felfly H, Garcia D, Cloutier G.
Laboratory of Biorheology and Medical Ultrasonics, University of Montreal Hospital Research Center, Montreal, Canada.
Physiol Genomics 2006, Nov 28; [Epub ahead of print]

Integrin-linked kinase expression is elevated in human cardiac hypertrophy and induces hypertrophy in transgenic mice.
Lu H, Fedak PW, Dai X, Du C, Zhou YQ, Henkelman M, Mongroo PS, Lau A, Yamabi H, Hinek A, Husain M, Hannigan G, Coles JG.
Cancer Research Program, Research Institute, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada..
Circulation. 2006 Nov 21;114(21):2271-9. Epub 2006 Nov 6.

Validation of the Wall Motion Score and Myocardial Performance Indices As Novel Techniques to Assess Cardiac Function in Mice Post Myocardial Infarction
Zhang Y, Takagawa J, Sievers R, Khan MF, Viswanathan M, Springer ML, Foster E, Yeghiazarians Y.
Medicine, Division of Cardiology, University of California, San Francisco, San Francisco, California, United States.
Am J Physiol Heart Circ Physiol 2006 Oct 6;

Fetal mouse imaging using echocardiography: a review of current technology.
Spurney CF, Lo CW, Leatherbury L.
Division of Cardiology, Children's National Medical Center, Washington, DC.
Echocardiography 2006 Nov;23(10):891-9

Characterization of Digital Waveforms Using Thermodynamic Analogs: Detection of Contrast-Targeted Tissue In Vivo.
Michael S. Hughes, Member, IEEE, Jon N. Marsh, Member, IEEE, Hyuing Zhang, Adam K. Woodson, John S. Allen, Elizabeth K. Lacy, Cordelia Carradine, Gregory M. Lanza, and Samuel A. Wickline,
Washington University School of Medicine MO
IEEE transactions on ultrasonics, ferroelectrics, and frequency control vol. 53, no. 9, september 2006

Hemodynamics in the Mouse Aortic Arch as Assessed by MRI, Ultrasound and Numerical Modeling.
Feintuch A, Ruengsakulrach P, Lin A, Zhang J, Zhou Y, Bishop J, Davidson L, Courtman D, Foster FS, Steinman D, Henkelman RM, Ethier CR.
Mouse Imaging Centre, Hospital for Sick Children, Toronto, Canada.
Am J Physiol Heart Circ Physiol 2006 Sep 29;

Therapy-Induced Acute Recruitment of Circulating Endothelial Progenitor Cells to Tumors
Shaked Y, Ciarrocchi A, Franco M, Lee CR, Man S, Cheung AM, Hicklin DJ, Chaplin D, Foster FS, Benezra R, Kerbel RS.
Department of Molecular and Cellular Biology Research, Sunnybrook Health Sciences Centre, Toronto
SCIENCE VOL 313 22 SEPTEMBER 2006, PP. 1785 – 1787.

The Use of Targeted Mouse Models for Preclinical Testing of Novel Cancer Therapeutics
Kenneth P. Olive and David A. Tuveson
University of Vermont, Cardiovascular Research Institute Burlington, VT, USA.
Clinical Cancer Research Vol. 12, 5277-5287, September 15, 2006

Insulin resistance increases PAI-1 in the heart.
Burton E. Sobel *, David J. Schneider, Yong-Ho Lee, Richard E. Pratley
University of Vermont, Cardiovascular Research Institute Burlington, VT, USA.
Biochemical and Biophysical Research Communications 346., 2006 102–107.

Layer acquisition by cortical GABAergic interneurons is independent of Reelin signaling.
Pla R, Borrell V, Flames N, Marin O.
Instituto de Neurociencias de Alicante, Consejo Superior de Investigaciones Cientificas and Universidad Miguel Hernandez, 03550 Sant Joan d'Alacant, Spain.
J Neurosci. 2006 Jun 28;26(26):6924-34.

Rapid dilation of the abdominal aorta during infusion of angiotensin II detected by noninvasive high-frequency ultrasonography.
Barisione C, Charnigo R, Howatt DA, Moorleghen JJ, Rateri DL, Daugherty A.
Cardiovascular Research Center, University of Kentucky, Lexington, KY; Division of Cardiology and Laboratory of Cardiovascular Biology, Department of Internal Medicine, University of Genova, Genova, Italy.
J Vasc Surg. 2006 Aug;44(2):372-6.

Overexpression of Bone Morphogenetic Protein 10 in Myocardium Disrupts Cardiac Postnatal Hypertrophic Growth.
Hanying Chen, Weidong Yong, Shuxun Ren, Weihua Shen, Yongzheng He, Karen A. Cox, Wuqiang Zhu, Wei Li, Mark Soonpaa, R. Mark Payne, Diego Franco, Loren J. Field, Vicki
Journal Of Biological Chemistry JBC Papers in Press, June 23, 2006.

Improved Cardiac Function in Infarcted Mice After Treatment With Pluripotent Embryonic Stem Cells.
TIMOTHY J. NELSON, ZHI-DONG GE, JORDAN VAN ORMAN, MATTHEW BARRON,DIANE RUDY-REIL, TIMOTHYA. HACKER, RAVI MISRA, STEPHEN A. DUNCAN, JOHN A. AUCHAMPACH, AND JOHN W. LOUGH
Department of Cell Biology, Neurobiology, and Anatomy and the Cardiovascular Center Medical College of Wisconsin, Department of Pharmacology and Toxicology and the Cardiovascular Center Medical
Milwaukee, Wisconsin
The Anatomical Record Part A 288A:1216–1224 (2006)

Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts.
Zimmermann WH, Melnychenko I, Wasmeier G, Didie M, Naito H, Nixdorff U, Hess A, Budinsky L, Brune K, Michaelis B, Dhein S, Schwoerer A, Ehmke H, Eschenhagen T.
Institute of Experimental and Clinical Pharmacology, University Medical Center Hamburg-Eppendorf, Germany. w.zimmermann@uke.uni-hamburg.de
Nat Med. 2006 Apr;12(4):452-8. Epub 2006 Apr 2

Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction.
Perrino C, Prasad SV, Mao L, Noma T, Yan Z, Kim HS, Smithies O, Rockman HA.
Duke University Medical Center, Durham, North Carolina, USA.
J Clin Invest. 2006 Jun;116(6):1547-60.

Transgenic expression of Angiopoietin 1 in the liver leads to changes in lymphatic and blood vessel architecture.
Haninec AL, Voskas D, Needles A, Brown AS, Stuart Foster F, Dumont DJ.
Divisions of Molecular and Cellular Biology Research, Sunnybrook and Women's Research Institute, Toronto, Ont., Canada;
Department of Medical Biophysics, University of Toronto, Toronto, Ont., Canada.
Biochem Biophys Res Commun. 2006 Jul 14;345(4):1299-1307. 2006 May 4

Rapamycin improves lymphoproliferative disease in murine autoimmune lymphoproliferative syndrome (ALPS).
Teachey DT, Obzut DA, Axsom K, Choi JK, Goldsmith KC, Hall J, Hulitt J, Manno CS, Maris JM, Rhodin N, Sullivan KE, Brown VI, Grupp SA.
University of PA School of Medicine/The Children's Hospital of Philadelphia.
Blood. 2006 Jun 6.

Competitive displacement of phosphoinositide-3 kinase from {beta}-adrenergic receptor kinase-1 improves post-infarction adverse myocardial remodeling.
Curcio A, Noma T, Naga Prasad SV, Wolf MJ, Lemaire A, Perrino C, Mao L, Rockman HA.
Department of Medicine, Cell biology and Genetics, Duke University Medical Center, Durham, North Carolina, United States.
Am J Physiol Heart Circ Physiol. 2006 May 12.

Gene expression profile and aortic vessel distensibility in voluntarily exercised spontaneously hypertensive rats: potential role of heat shock proteins.
Ulrika Hägg¹, Maria E. Johansson1, Julia Grönros¹, Andrew S. Naylor¹, Ingibjörg H. Jonsdottir^1,3, Göran Bergström^1,2, Per-Arne Svensson⁴ and Li-ming Gan1,^2
1 Department of Physiology, Institute of Physiology and Pharmacology, Göteborg University;² Department of Clinical Physiology, Cardiovascular Institute, Sahlgrenska University Hospital, Göteborg, Sweden
Physiol. Genomics , 22: 319-326, May 24, 2005

Phospholipase C-delta1 is a critical target for tumor necrosis factor receptor-mediated protection against adriamycin-induced cardiac injury.
Lien YC, Noel T, Liu H, Stromberg AJ, Chen KC, St Clair DK.
Graduate Center for Toxicology, Department of Statistics, University of Kentucky, Lexington, Kentucky 40536, USA.
Cancer Res. 2006 Apr 15;66(8):4329-38.

Imaging Tools for the Developmental Biologist: Ultrasound Biomicroscopy of Mouse Embryonic Development.
Phoon CK.
Pediatric Cardiology Program, New York University School of Medicine, New York, NY 10016.
Pediatric Research, 2006 May 11;

Volume measurement variability in three-dimensional high-frequency ultrasound images of murine liver metastases.
Wirtzfeld LA, Graham KC, Groom AC, Macdonald IC, Chambers AF, Fenster A, Lacefield JC.
Biomedical Engineering Graduate Program, University of Western Ontario, Imaging Research Laboratories, Robarts Research Institute, London, Ontario.
Phys Med Biol. 2006 May 21;51(10):2367-81. Epub 2006 Apr 26.

Non-invasive real-time imaging of atherosclerosis in mice using ultrasound biomicroscopy.
Gan LM, Gronros J, Hagg U, Wikstrom J, Theodoropoulos C, Friberg P, Fritsche-Danielson R.
Department of Physiology, Institute of Physiology and Pharmacology, The Sahlgrenska Academy, Goteborg University, Goteborg, Sweden; Department of Clinical Physiology, Institute of Cardiovascular Disease, The Sahlgrenska Academy, Goteborg University, Goteborg, Sweden; AstraZeneca, R&D, Molndal, Sweden.
Atherosclerosis. 2006 May 3;

Ultrahigh frame rate retrospective ultrasound micro-imaging and blood flow visualization in mice in vivo.
Emmanuel Chérin, Ross Williams, Andrew Needles, Godwin Liu, Christopher White, Allison S. Brown, Yu-Qing Zhou and F. Stuart Foster
Ultrasound in Medicine & Biology, Volume 32, Issue 5 , May 2006, PP. 683-691

Emerging imaging techniques.
McVeigh ER.
Laboratory of Cardiac Energetics, NHLBI, National Institutes of Health, Bethesda, MD, USA. emcveigh@nih.gov
Circ Res. 2006 Apr 14;98(7):879-86.

Emilin1 links TGF-beta maturation to blood pressure homeostasis.
Zacchigna L, Vecchione C, Notte A, Cordenonsi M, Dupont S, Maretto S, Cifelli G, Ferrari A, Maffei A, Fabbro C, Braghetta P, Marino G, Selvetella G, Aretini A, Colonnese C, Bettarini U, Russo G, Soligo S, Adorno M, Bonaldo P, Volpin D, Piccolo S, Lembo G, Bressan GM.
Developmental Signaling Laboratory, Department of Histology Microbiology and Medical Biotechnologies, University of Padua, viale Colombo 3, 35121 Padua, Italy.
Cell 2006 Mar 10;124(5):893-5.

Investigating perfluorohexane particles with high-frequency ultrasound.
Couture O, Bevan PD, Cherin E, Cheung K, Burns PN, Foster FS.
Imaging Research, Sunnybrook Health Sciences Centre, Toronto
Ultrasound Med Biol. 2006 Jan;32(1):73-82.

Nanosecond pulsed electric fields cause melanomas to self-destruct.
Richard Nuccitelli^a, ^bUwe Pliquett^a, Xinhua Chen^a, Wentia Ford^a, R. James Swansona, Stephen J. Beebe^{a, c}, Juergen F. Kolb^a and Karl H. Schoenbach^a
aFrank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA, bBioElectroMed Corp., Norfolk, VA
^cEastern Virginia Medical School, Norfolk, VA
Received 11 February 2006. Available online 10 March 2006.
Biochem Biophys Res Commun. 2006 Mar 10; [Epub ahead of print]

Cardiovascular Function in Mice During Normal Pregnancy and in the Absence of Endothelial NO Synthase.
Kulandavelu S, Qu D, Adamson SL.
Samuel Lunenfeld Research Institute at Mount Sinai Hospital, and Departments of Physiology, and Obstetrics and Gynecology, University of Toronto, Toronto, Ontario, Canada.
Hypertension. 2006 Apr 24.

Nanoparticles as image enhancing agents for ultrasonography.
Liu J, Levine AL, Mattoon JS, Yamaguchi M, Lee RJ, Pan X, Rosol TJ.
Biomedical Engineering Department, The Ohio State University, Columbus, OH
Phys Med Biol. 2006 May 7;51(9):2179-89

Developmental changes in hemodynamics of the uterine artery, the utero- and umbilico-placental, and vitelline circulations in the mouse throughout gestation.
Mu J, Adamson SL.
Departments of Obstetrics and Gynecology and Physiology, University of Toronto, Samuel Lunenfeld Research Institute of Mount Sinai Hospital, Toronto, Canada.
Am J Physiol Heart Circ Physiol. 2006 Apr 7;

Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome.
Jennifer P. Habashi,1* Daniel P. Judge,2* Tammy M. Holm,1 Ronald D. Cohn,1 Bart L. Loeys,1 Timothy K. Cooper,1,3 Loretha Myers,1 Erin C. Klein,1 Guosheng Liu,3 Carla Calvi,2 Megan Podowski,2 Enid R. Neptune,2 Marc K. Halushka,4 Djahida Bedja,3 Kathleen Gabrielson,3 Daniel B. Rifkin,5 Luca Carta,6 Francesco Ramirez,6 David L. Huso,3 Harry C. Dietz1,2†
1Howard Hughes Medical Institute and Department of Pediatrics, 2Department of Medicine, 3Department of Molecular and Comparative Pathobiology, 4Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. 5Departments of Cell Biology and Medicine, New York University School of Medicine, New York, NY 10016, USA. 6Child Health Institute of New Jersey, University of Medicine and Dentistry of New Jersey–Robert Wood Johnson Medical School, New Brunswick, NJ 08903,
Science. 2006 Apr 7;312(5770):117-21.

Targeted anti-vascular endothelial growth factor receptor-2 therapy leads to short-term and long-term impairment of vascular function and increase in tumor hypoxia.
Franco M, Man S, Chen L, Emmenegger U, Shaked Y, Cheung AM, Brown AS, Hicklin DJ, Foster FS, Kerbel RS.
Molecular and Cellular Biology Research, Sunnybrook and Women's College Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada M4N 3M5.
Cancer Research, 2006 Apr 1;66(7):3639-48.

Evaluation of an algorithm for semi-automated segmentation of thin tissue layers in high-frequency ultrasound images
Qiang Qiu; Dunmore-Buyze, J.; Boughner, D. R.; and Lacefield, J. C.
Robarts Res. Inst., Western Ontario Univ., London, Ont.
IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency, Vol. 53, Feb. 2006

Validation of Ultrasonography to Evaluate Murine Orthotopic Oral Cavity Tumors
Pezold JC, Zinn K, Talbert MA, Desmond R, Rosenthal EL.
Department of Surgery, Division of Otolaryngology - Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, Ala., USA.
ORL J Otorhinolaryngol Relat Spec. 2006 Feb 6;68(3):159-163

Fibroblast-derived MT1-MMP promotes tumor progression in vitro and in vivo
Wenyue Zhang, Lynn M Matrisian, Kenn Holmeck, Catherine C Vick and Eben L Rosenthal
Department of Surgery, Division of Otolaryngology - Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, Ala., USA.
BMC Cancer 6 March 2006, 6:52 doi:10.1186/1471-2407-6-52

Embryonic and Neonatal Phenotyping of Genetically Engineered Mice
Shathiyah Kulandavelu, Dawei Qu, Nana Sunn, Junwu Mu, Monique Y. Rennie,
Kathie J. Whiteley, Johnathon R. Walls, Nicholas A. Bock, John C. H. Sun, Andrea Covelli, John G. Sled, and S. Lee Adamson
Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario
ILAR Journal, March 2006, Vol. 47, #2

High resolution ultrasound-guided microinjection for interventional studies of early embryonic and placental development in vivo in mice
John C. Slevin, Lois Byers, Marina Gertsenstein, Dawei Qu, Junwu Mu, Nana Sunn, John C.P. Kingdom, Janet Rossant and S. Lee Adamson
BMC Developmental Biology, 2006, 6:10 doi:10.1186/1471-213X-6-10, February 2006

Neurogenic Mechanisms Contribute to Hypertension in Mice With Disruption of the K-Cl Cotransporter KCC3.
Rust MB, Faulhaber J, Budack MK, Pfeffer C, Maritzen T, Didie M, Beck FX, Boettger T, Schubert R, Ehmke H, Jentsch TJ, Hubner CA.
Zentrum fur Molekulare Neurobiologie Hamburg, Universitat Hamburg; Institut fur Vegetative Physiologie und Pathophysiologie, Institut fur Experimentelle und Klinische Pharmakologie, and Institut fur Humangenetik, Universitatsklinikum Hamburg-Eppendorf, Hamburg; Physiologisches Institut, Ludwig-Maximilians-Universitat Munchen; and Institut fur Physiologie, Universitat Rostock, Germany.
Circ Res, 2006 Mar 3;98(4):549-56.

The administration of human ghrelin attenuates development of cardiac cachexia in rats with heart
Y Akashi¹, J Springer¹, S Palus¹, R Datta², H Halem², J Dong², M
Culler², S Anker^1
1 Angewandte Kachexieforschung, Charité
² IPSEN, Milford, Massachusetts, USA
Akt Ernähr Med 2006; 31

Imaging the Cardiovascular System: Seeing Is Believing
Thomas K. Borg,, James A. Stewart, Jr., and Michael A. Sutton
1 Department of Cell and Developmental Biology and
2 Department of Mechanical Engineering and Anatomy, University of South Carolina, Columbia, SC
Microscopy and Microanalysis 11, 189–199, 2005.

The Proximal to Middle Left Coronary Artery Flow Velocity Ratio, As Assessed Using Color Doppler Echocardiography, Predicts Coronary Artery Atherosclerosis in Mice
Julia Gro¨nros, Johannes Wikstro¨m, Ulrika Ha¨gg, Birger Wandt, Li-ming Gan
Department of Physiology, Institute of Physiology and Pharmacology, and the Department of Clinical Physiology, Cardiovascular Institute, The Sahlgrenska Academy, Goteborg University, Sweden.
Arterioscler Thromb Vasc Biol, 2006 Mar 2;

Neurogenic Mechanisms Contribute to Hypertension in Mice With Disruption of the K-Cl Cotransporter KCC3
Rust MB, Faulhaber J, Budack MK, Pfeffer C, Maritzen T, Didie M, Beck FX, Boettger T, Schubert R, Ehmke H, Jentsch TJ, Hubner CA.
Zentrum fur Molekulare Neurobiologie Hamburg, Universitat Hamburg; Institut fur Vegetative Physiologie und Pathophysiologie, Institut fur Experimentelle und Klinische Pharmakologie, and Institut fur Humangenetik, Universitatsklinikum Hamburg-Eppendorf, Hamburg; Physiologisches Institut, Ludwig-Maximilians-Universitat Munchen; and Institut fur Physiologie, Universitat Rostock, Germany
Circ Res, 2006 Jan 19; [Epub ahead of print]

Monitoring Structural Changes In Cells With High-frequency Ultrasound Signal Statistics
A. S. Tunis,*‡ G. J. Czarnota,†‡§ A. Giles‡ M. D. Sherar,*†‡_ J. W. Hunt,*‡ And M. C. Kolios*
§ Departments of *Medical Biophysics and †Radiation Oncology, University of Toronto, Toronto, ONT, Canada;
‡ Ontario Cancer Institute/Princess Margaret Hospital, University Health Network, Toronto, ONT, Canada;
§ Department of Physics, Ryerson University, Toronto, ONT, Canada; and _London Regional Cancer Centre/London
Health Sciences Centre and Department of Oncology, University of Western Ontario, London, ONT, Canada
Ultrasound in Med. & Biol., Vol. 31, No. 8, pp. 1041–1049, 2005

Low thyroid function leads to cardiac atrophy with chamber dilatation, impaired myocardial blood flow, loss of arterioles, and severe systolic dysfunction.
Jennifer L. Lucitti*, Kimimasa Tobita and Bradley B. Keller
Division of Pediatric Cardiology, Department of Pediatrics, Children’s Hospital of Pittsburgh of UPMC
The Journal of Experimental Biology, 2005 Nov 15;112(20):3122-30.

Arterial hemodynamics and mechanical properties after circulatory intervention in the chick embryo.
Tang YD, Kuzman JA, Said S, Anderson BE, Wang X, Gerdes AM.
Cardiovascular Research Institute, South Dakota Health Research Foundation, University of South Dakota School of Medicine, Sioux Valley Hospitals and Health Systems, Sioux Falls, SD, USA.
Circulation., 208, 1877-1885, 2005

NAD(P)H Oxidase and Multidrug Resistance Protein Genetic Polymorphisms Are Associated With Doxorubicin-Induced Cardiotoxicity
Leszek Wojnowski, MD; Bettina Kulle, PhD; Markus Schirmer, MD; Gregor Schlüter, MD; Albrecht Schmidt, MD; Albert Rosenberger, PhD; Stefan Vonhof, MD; Heike Bickeböller, PhD; Mohammad Reza Toliat, PhD; Eun-Kyung Suk, PhD; Mladen Tzvetkov, PhD; Anke Kruger, PhD; Silvia Seifert, MSc; Marita Kloess, PhD; Heidi Hahn, MD; Markus Loeffler, MD; Peter Nürnberg, PhD; Michael Pfreundschuh, MD; Lorenz Trümper, MD; Jürgen Brockmöller, MD; Gerd Hasenfuss, MD
From the Department of Pharmacology, University Mainz, Mainz, Germany (L.W., A.K.); Departments of Genetic Epidemiology (B.K., A.R., H.B.), Clinical Pharmacology (L.W., M.S., M.T., J.B.), Human Genetics, (G.S., S.S., H.H.), Cardiology and Pneumonology (A.S., S.V., G.H.), and Hematology and Oncology (L.T.), University Göttingen, Göttingen, Germany; Gene Mapping Center, Max-Delbrück Center, Berlin, Germany (M.R.T., E.S., P.N.); Cologne Center for Genomics, University of Cologne, Cologne, Germany (M.R.T., P.N.); Institute for Medical Informatics, Statistics, and Epidemiology, Leipzig, Germany (M.K., M.L.); Department of Internal Medicine I, University of Saarland, Homburg, Germany (M.P.); and Departments of Biostatistics and Mathematics, University of Oslo, Oslo, Norway (B.K.).
Circulation 2005 Dec 13;112(24):3754-62. Epub 2005