Because of its high-resolution imaging and the ability to provide real-time visualization, the Vevo 770 can visualize and guide injections of cells, drugs, genetic material or metabolic agents into developing small animal embryos in utero. The system can also be used for extraction procedures.







Many neurobiological applications such as monitoring of embryonic or neonatal brain development, study of cell lineage, and the study of progressive neural degenerative diseases associated with mouse models can be complimented with the use of the Vevo 770 high-resolution imaging system. In addition, although ultrasound is unable to penetrate bone, the Vevo 770 successfully provides high-resolution images of the neonate mouse brain prior to ossification of the skull.

Features and Benefits of the Vevo 770 High-Resolution Imaging System for Neurobiology:
  • >  Real-time visualization of image-guided needle injections and extractions: Targeted needle injections of cells, genetic material, drugs and retroviruses can be visualized in real-time in small animal embryos through to adulthood.

  • >  Assists in study of cell lineage and fate in mouse embryos: The Vevo 770 can assist in the study of cell lineage and fate in mouse embryos using both retroviruses and trasfected cell lines expressing secreted proteins.

  • >  Monitor Small Animal Brain Development: Due to the extremely high-resolution images that can be derived, the Neurobiologist can image and study embryonic and neonatal brain development. The non-invasive nature of the system allows for longitudinal study of the same mouse.

  • >  The integrated image-guided needle injection system is easy to learn and to obtain results: The Vevo 770 is simple to use so that researchers can maximize their time performing post-imaging analysis. The integrated rail system and image-guided needle injection system are easily mounted, prepared and operated. Precision adjustments are easily made to ensure that the RMV Scanhead, the injection system, and the mouse table are all in alignment to most effectively ensure a successful procedure.



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