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In addition, VisualSonics has developed accompanying
accessories to ensure that the small animal is maintained in the
most stable state during imaging. Not only does this ensure the humane
treatment of the animal, it also ensures that the cardio-related
stress on the animal is minimized therefore ensuring a more "regulated" environment and consequently, a more accurate imaging result:
- > Integrated Rail System and
Mouse Handling Table is a system
for quickly and efficiently setting-up a comfortable environment
for effective imaging of a small animal. The
rail system is adjustable and aligns the RMV
scanhead and the mouse, which is placed on
a heated table once anesthetized. The table
is heated to ensure the stability of the mouse's
temperature during the procedure and allows
monitoring of the mouse's
ECG.
- > Integrated Isoflurane-Based
Anesthesia System is
a compact Isoflurane-based anesthesia system
for small animals. The system is available
in a desktop version or as a trolley-mounted
version. Once anesthetized in the chamber,
the mouse is placed on the heated table.
The anesthesia tubes and small-animal mask
are integrated into the table apparatus so
that the researcher can easily move the table
and maneuver the mouse without disrupting
the flow of anesthesia.
Features and Benefits of the Vevo 770 High-Resolution Imaging System for Cardiovascular Research:
- > Quantitative Evaluation of
Physiological Function and Development of
Mouse Heart: Real-time
evaluation and quantification of physiological
function of the developing mouse heart and
the associated major vessels.
- > Evaluation of cardiovascular
therapies: The Vevo 770 can also be used or evaluating the effectiveness
of cardiovascular therapies in mouse models.
The non-invasive nature of the system allows
longitudinal analysis (studying treatment
effectiveness in the same animal over time).
- > Reduce Stress on Animal Through
Heated Mouse Table: The heated table that the mouse rests on
during the imaging session is heated to ensure
stability of the animal's temperature and
to maintain as normal a heart rate as possible.
- > Extensive Measurement and
Annotation Functionality: The
Vevo software provides measurement and annotation
functionality that allows the cardiovascular
researcher to conduct comprehensive analysis
for monitoring and measuring the progression
of disease and the efficacy of therapeutics.
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