Anatomical M-Mode allows the user to steer the sample volume to any angle they choose, rather than having the sample volume in a strict vertical position

Anatomical M-Mode is a modification to the standard M-Mode typically used in echocardiography; Anatomical M-Mode allows the user to steer the sample volume to any angle they choose, rather than having the sample volume in a strict vertical position.

Anatomical M-Mode can be used to place the sample volume through the papillary muscles which are located on the lateral wall in rodents such as mice, and therefore the other wall interrogated is the interventricular septum. Additional measurements were added to the Vevo 2100 software to allow for appropriate measurement of the lateral wall, resulting calculations giving the same values of the cardiac function as from the standard M-Mode imaging. These additional measurements are only available when an image is acquired in Anatomical M-Mode. This option is available for both the Vevo 2100 and Vevo 770 Imaging Systems.

A typical Anatomical M-Mode image with an angled sample volume. Standard measures of interventricular septum (IVS), left ventricle interior diameter (LVID), and lateral wall (LW), are made in systole and diastole.