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Dr. Gambhir is a recognized world leader in the area of molecular imaging of cancer. His laboratory at Stanford University is at the center of bringing together scientists from different disciplines in order to advance the field of molecular imaging. His lab pioneered the use of reporter gene technologies for living animals and then applied this to imaging gene therapy, imaging cell trafficking, developing mouse models of cancer, stem cell imaging, imaging of intra-cellular networks, as well as several other areas. He has also translated several approaches to clinical molecular imaging.
His research interests are directed at the development of techniques to study various molecular/biochemical events taking place in living animals and humans, in their natural state, at the cellular and sub-cellular levels.
Dr. Gambhir is the Director of the Stanford School of Medicine Program in Molecular Imaging. He is a Professor of Radiology and Bioengineering and Head of the Division of Nuclear Medicine. He holds a B.S. in Physics from Arizona State University and a Ph.D. in Biomathematics and M.D., both from University of California Los Angeles.
His accomplishments include
over 260 published papers and more than 16 patents awarded or pending and he has been lauded with awards both nationally and internationally including the 2008 Tesla Medal presented by the United Kingdom Royal College of Radiologists in England for his work in Multimodality Molecular Imaging of Living Subjects as well as the Paul C. Aebersold Award (2006) by the Society of Nuclear Medicine and the Hounsfield Medal (2006) by Imperial College London.
Recent Publications
- > Abhijit De X Z Lewis S S Gambhir. Noninvasive Imaging of Lentiviral Mediated Reporter Gene Expression in Living Mice. Molecular Therapy. 2003; 7(5): 681-691
- > D. Wu and S.S. Gambhir. Positron Emission Tomorgraphy in Diagnosis and Management of Invasive Breast Cancer: Current Status and Future Perspectives. Clinical Breast Cancer. 2003; 4(Suppl 1): S55-S63
- > I. Hildebrandt, M. Iyer, E. Wagner, S.S. Gambhir. Optical Imaging of Transferrin Targeted PEI/DNA Complexes in Living Subjects. Gene Therapy. 2003; 10():
758 - 764
- > M. Inubushi, J. Wu, S.S. Gambhir, G. Sundaresan, N. Satyamurthy, M. Namavari, S. Yee, J.R. Barrio, D. Stout, A. Chatziioannou, L. Wu, H.R. Schelbert. PET Reporter Gene Expression Imaging in Rat Myocardium. Circulation. 2003; 107(2): 326-332
- > P. Dubey, H. Su, N. Adonai, S. Du, A. Rosato, J. Braun, S.S. Gambhir, O. Witte. Quantitative Imaging of the T Cell Anti-Tumor Response by Positron Emission Tomography. Proceedings of the National Academy of Science (USA). 2003; 100(3): 1232-1237
- > P. Ray, A. Wu, S.S. Gambhir. Optical Bioluminescence and Positron Emission Tomography Imaging of a Novel Fusion Reporter Gene in Tumor Xenografts of Living Mice. Cancer Research. 2003; 63(): 1160 - 1165
- > R. Paulmurugan and S.S. Gambhir. Monitoring Protein-Protein Interactions Using Split Synthetic Renilla Luciferase Protein Fragment Assisted Complementation. Analytical Chemistry. 2003; 75(7): 1584-1589
- > T. Massoud and S.S. Gambhir. Molecular Imaging in Living Subjects: Seeing Fundamental Biological Processes in a New Light. Genes & Development. 2003; 17(5): 545 - 580
- > A. Pantuck, F. Berger, A. Zisman, D. Nguyen, C. Tso, J. Matherly, S.S. Gambhir, A. Belldegrun. CL1-SR93: A Non-invasive Molecular Imaging Model of Prostate Cancer Suicide Gene Therapy using Positron Emission Tomography. Journal of Urology. 2002; 168(3): 1193-8
- > A. Pantuck, J. Matherly, A. Zisman, D. Nguyen, F. Berger, S.S. Gambhir, M. Black, A. Belldegrun, L. Wu. Optimizing Prostate Cancer Suicide Gene Therapy using Herpes Simplex Virus Thymidine Kinase Active Site Variants. Human Gene Therapy. 2002; 13(): 777-789
- > D.H. Silverman, S.S. Gambhir, H.W. Huang, J. Schwimmer, S. Kim, G.W. Small, J. Chodosh, J. Czernin, M.E. Phelps. Evaluating Early Dementia With and Without Assessment of Regional Cerebral Metabolism by PET: A Comparison of Predicted Costs and Benefits. Journal of Nuclear Medicine. 2002; 43(2): 253-266
- > F. Berger, Y.P. Lee, AM. Loening, A. Chatziioannou, C.L. Tso, S. Freedland, R. Leahy, J.R. Liberman, A. Beldegrun, C.L. Sawyers, S.S. Gambhir. Whole Body Skeletal Imaging in Mice Utilizing MicroPET and MicroCAT: New Tools for Small Animal Bone Imaging. European Journal of Nuclear Medicine. 2002; 29(9):
1225-1236
- > J. Wu, M. Inubushi, G. Sundaresan, H. Schelbert, S.S. Gambhir. Optical Imaging of Cardiac Reporter Gene Expression in Living Rats. Circulation. 2002; 105():
1631-1634
- > J. Wu, M. Inubushi, G. Sundaresan, H.R. Schelbert, S.S. Gambhir . Positron Emission Tomography Imaging of Cardiac Reporter Gene Expression in Living Rats. Circulation. 2002; 106( 2): 180-183
- > Annals of Letters to the editor. K.C. Park, J. Schwimmer, S.S. Gambhir.
Surgery. 2002; 235(2): 309-10
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